scholarly journals Beyond Coronary Calcification, Family History, and C-Reactive Protein

2016 ◽  
Vol 67 (21) ◽  
pp. 2480-2487 ◽  
Author(s):  
Purav Mody ◽  
Parag H. Joshi ◽  
Amit Khera ◽  
Colby R. Ayers ◽  
Anand Rohatgi
2005 ◽  
Vol 90 (12) ◽  
pp. 6418-6423 ◽  
Author(s):  
Peter C. Y. Tong ◽  
Chung-Shun Ho ◽  
Vincent T. F. Yeung ◽  
Maggie C. Y. Ng ◽  
Wing-Yee So ◽  
...  

Context: Age-related declines in testosterone and IGF-I are associated with deposition of visceral fat, a component of the metabolic syndrome (MES). Objective: Testosterone and IGF-I may interact with familial disposition to diabetes mellitus to increase the association with MES. Design: We conducted a cross-sectional cohort study. Setting: The study was conducted in a university teaching hospital. Subjects: Study subjects included 179 middle-aged men with a family history of diabetes (FH) (aged 39.1 ± 8.1 yr) and 128 men without FH (aged 43.8 ± 8.5 yr). Main Outcome Measures: Clinical characteristics, frequency of MES using the World Health Organization criteria with Asian definitions of obesity (body mass index ≥ 25 kg/m2), and serum levels of total testosterone, IGF-I, and high-sensitive C-reactive protein (hs-CRP) were measured. Results: Men with FH had higher frequency of MES than those without FH [39.1 vs. 23.4% (P = 0.004)]. On multivariate analysis, smoking (former and current smokers), low total testosterone, and IGF-I but elevated hs-CRP levels explained 35% of the MES variance in men with FH. The frequency of MES increased with declining tertiles of total testosterone and IGF-I but increasing tertiles of hs-CRP. After adjustment for age and smoking history, subjects with all three risk factors had a 13-fold increase in risk association with MES compared with those without hormonal and inflammatory risk factors. These risk associations were not found in men without FH in whom only smoking (ex and current) and low total testosterone level were independent predictors for MES, which explained 14% of the variance. Conclusions: Clustering of FH, hormonal abnormalities, and high hs-CRP is associated with MES in Chinese middle-aged men.


1999 ◽  
Vol 144 ◽  
pp. 17
Author(s):  
M. Margaglione ◽  
G. Cappucci ◽  
D. Colaizzo ◽  
G. Vecchione ◽  
E. Grandone ◽  
...  

Stroke ◽  
2006 ◽  
Vol 37 (8) ◽  
pp. 2001-2006 ◽  
Author(s):  
Riyaz Somani ◽  
Peter J. Grant ◽  
Kirti Kain ◽  
Andrew J. Catto ◽  
Angela M. Carter

2020 ◽  
Vol 17 (1) ◽  
pp. 3-8
Author(s):  
Md Mahboob Morshed ◽  
Md Joynul Islam ◽  
Fariha Haseen ◽  
Khandokar Shaheed Hussain ◽  
Muhammad Kamrul Amin ◽  
...  

Background: Haemoglobina and CRP level may be related with the in-hospital outcome of acute coronary syndrome patients. Objective: The purpose of the present study was to correlate haemoglobin and CRP level with in-hospital outcome of patient with acute coronary syndrome. Methodology: This cross-sectional study was conducted in the Department of Cardiology at Mymensingh Medical College, Mymensingh, Bangladesh from December 2010 to November 2011 for a period of two (02) years. Patients of ACS who were presented within 12 hours of chest pain were included as study population. Study population were categorized in four groups according to the level of hemoglobin and C-reactive protein. Blood sample was collected for baseline laboratory investigations. Result: The mean age of the population was 52.18±8.88 years. Arrhythmia was more common in Group 1 which was 5(71.4%) cases and 6(46.2%) cases in VT and AF respectively. Arrhythmia was significantly correlated with age, sex, diabetes mellitus & CRP. Death was significantly correlated with age, diabetes mellitus, hypertension & CRP. Heart failure was significantly correlated with family history of IHD, CRP & Hemoglobin. Bleeding was only significantly correlated with CRP. No significant association was revealed between the types of arrhythmia and age, sex, smoking, diabetes, dyslipidaemia, family history of IHD and hypertension (P = 0.087). Only heart failure was strongly and significantly correlated with hemoglobin level (p=0.000). Bleeding (p=0.003), heart failure (p=0.022) and death (p=0.016) were significantly correlated with CRP level. Conclusion: In conclusion there is a correlation of haemoglobin and CRP level with in-hospital outcome of patient with acute coronary syndrome. Journal of Science Foundation 2019;17(1):3-8


Circulation ◽  
2002 ◽  
Vol 106 (10) ◽  
pp. 1189-1191 ◽  
Author(s):  
Thomas J. Wang ◽  
Martin G. Larson ◽  
Daniel Levy ◽  
Emelia J. Benjamin ◽  
Michelle J. Kupka ◽  
...  

Author(s):  
Yonatan Esli Alexander Tidja ◽  
Sjahjenny Mustokoweni ◽  
Tania Ardiani Saleh

Introduction: Bone and joint tuberculosis are specific infection inflammation of Mycobacterium tuberculosis, mostly affected bone and joint confirmed by acceleration of vascular supply to vertebrae and growth line of long bone. The aim of this study is to know clinical profile of bone and joint tuberculosis’ patients. Methods: This study was conducted using descriptive observational method, samples were tested by observation descriptive test. Results: The average ages of bone and joint tuberculosis hospitalized patients of RSUD Dr. Soetomo Surabaya are 35-44 years. There are 22 cases on male (55%) and 18 cases on female (45%) with 29 subjects of Hb’s abnormal number (72.5%), 15 subjects of abnormal leucocytes (37.5%), 20 subjects of abnormal thrombocyte (50%), 34 subjects of abnormal ESR (94.4%), 20 patients of abnormal C-reactive protein (54.1%), 11 subjects of abnormal serum creatinine (28.9%), 13 subjects of abnormal sodium level (35.1%), 15 patients of abnormal potassium level (40.5%), and 16 patients of abnormal chloride level (43.2%). There are 16 subjects with smoking history (40%), 29 subjects of positive tuberculosis history (72.5%), 6 subjects with positive tuberculosis family history (15%), 30 subjects of pain as main problems (75%), 5 subjects of swelling or pus as main problems (12.5%), 5 subjects of extremities disability as main problems (12.5%). Dominant location of infection is vertebrae (95%) which are suffered by 38 subjects with thoracal as the main level of infection, suffered by 15 subjects (50%). Other levels of infection are lumbal with 12 subjects (40%), cervical with 3 subjects (10%), and pelvis or thigh with 2 subjects (5%). Conclusion: From 40 subjects, bone and joint tuberculosis mostly suffered by elderly, male risks more than female. Most of hematology tests results were abnormal. Most subjects suffered abnormal C-reactive protein. Most subjects’ hematology tests were BUN, creatinine serum, and electrolyte normal. Number of subjects with smoking habits was dominant. Most subjects were having tuberculosis history but negative family history. Most subjects complained about pain with vertebrae level thoracal as dominant location of infection.


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