scholarly journals Enhanced antibacterial activity of streptomycin against some human pathogens using green synthesized silver nanoparticles

2015 ◽  
Vol 1 (2) ◽  
pp. 106-115 ◽  
Author(s):  
Raj Kumar Salar ◽  
Pooja Sharma ◽  
Naresh Kumar
2019 ◽  
Vol 18 (01) ◽  
pp. 1850011 ◽  
Author(s):  
S. Balasubramanian ◽  
U. Jeyapaul ◽  
S. Mary Jelastin Kala

In the present study, bio-meditated silver nanoparticles have been synthesized using Jasminum auriculatum stem extracts. The silver nanoparticles were confirmed using UV-visible and FT-IR spectra. The size and morphology of silver nanoparticles were confirmed using XRD, SEM and EDAX techniques. The antibacterial activity of green synthesized silver nanoparticles was assessed by disc diffusion method against human pathogens. The antibacterial studies indicate that green synthesized silver nanoparticles have several pharmaceutical applications for the management of deadly human pathogens.


AMB Express ◽  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Susanna Gevorgyan ◽  
Robin Schubert ◽  
Mkrtich Yeranosyan ◽  
Lilit Gabrielyan ◽  
Armen Trchounian ◽  
...  

AbstractThe application of green synthesis in nanotechnology is growing day by day. It’s a safe and eco-friendly alternative to conventional methods. The current research aimed to study raw royal jelly’s potential in the green synthesis of silver nanoparticles and their antibacterial activity. Royal jelly served as a reducing and oxidizing agent in the green synthesis technology of colloidal silver nanoparticles. The UV–Vis maximum absorption at ~ 430 nm and fluorescence emission peaks at ~ 487 nm confirmed the presence of Ag NPs. Morphology and structural properties of Ag NPs and the effect of ultrasound studies revealed: (i) the formation of polydispersed and spherical particles with different sizes; (ii) size reduction and homogeneity increase by ultrasound treatment. Antibacterial activity of different concentrations of green synthesized Ag NPs has been assessed on Gram-negative S. typhimurium and Gram-positive S. aureus, revealing higher sensitivity on Gram-negative bacteria.


Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 3790
Author(s):  
Pratama Jujur Wibawa ◽  
Muhammad Nur ◽  
Mukhammad Asy’ari ◽  
Wijanarka Wijanarka ◽  
Heru Susanto ◽  
...  

This research aimed to enhance the antibacterial activity of silver nanoparticles (AgNPs) synthesized from silver nitrate (AgNO3) using aloe vera extract. It was performed by means of incorporating AgNPs on an activated carbon nanoparticle (ACNPs) under ultrasonic agitation (40 kHz, 2 × 50 watt) for 30 min in an aqueous colloidal medium. The successful AgNPs synthesis was clarified with both Ultraviolet-Visible (UV-Vis) and Fourier Transform Infrared (FTIR) spectrophotometers. The successful AgNPs–ACNPs incorporation and its particle size analysis was performed using Transmission Electron Microscope (TEM). The brown color suspension generation and UV-Vis’s spectra maximum wavelength at around 480 nm confirmed the existence of AgNPs. The particle sizes of the produced AgNPs were about 5 to 10 nm in the majority number, which collectively surrounded the aloe vera extract secondary metabolites formed core-shell like nanostructure of 8.20 ± 2.05 nm in average size, while ACNPs themselves were about 20.10 ± 1.52 nm in average size formed particles cluster, and 48.00 ± 8.37 nm in average size as stacking of other particles. The antibacterial activity of the synthesized AgNPs and AgNPs-immobilized ACNPs was 57.58% and 63.64%, respectively (for E. coli); 61.25%, and 93.49%, respectively (for S. aureus). In addition, when the AgNPs-immobilized ACNPs material was coated on the cotton and polyester fabrics, the antibacterial activity of the materials changed, becoming 19.23% (cotton; E. coli), 31.73% (polyester; E. coli), 13.36% (cotton; S. aureus), 21.15% (polyester; S. aureus).


2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Asra Parveen ◽  
Manjunath S. Yalagatti ◽  
Venkataraman Abbaraju ◽  
Raghunandan Deshpande

Antimicrobial study of biofunctionalized silver nanoparticles has been done with the emphasis on its mechanism on both gram positive and negative bacteria. The biofunctionalized silver nanoparticles are employed considering their importance in green chemistry with respect to easy synthesis, usefulness, and economic synthetic procedure involved. The stability of these nanoparticles was determined by zeta potential analyzer. The probable mechanism of antibacterial activity was performed on Proteus mirabilis by field emission scanning electron microscopy (FESEM) and energy dispersive spectroscopy (EDAX) study which does not show the presence of silver. The free radicals generated by silver nanoparticles were responsible for lethal antibacterial activity by rupturing the cell surface which causes improper nutrient and signal supply. Free radical scavenging efficacy of silver nanoparticles was confirmed by 1,1-Diphenyl-2-picrylhydrazyl (DPPH) method. AgNP enhanced the membrane leakage of reducing sugars by destroying the proteins existing on the cell wall. These nanoparticles are found to be toxic against human pathogens and are highly effective on Staphylococcus aureus. The effect of silver nanoparticles is concentration dependent and independent of the type of strains used.


2013 ◽  
Vol 4 (7) ◽  
pp. 881-888 ◽  
Author(s):  
N. Shanmugam ◽  
P. Rajkamal ◽  
S. Cholan ◽  
N. Kannadasan ◽  
K. Sathishkumar ◽  
...  

Author(s):  
Pandiarajan. P ◽  
Andrew Pradeep ◽  
Januja J ◽  
Dhurairaj Satheesh

The Emergence of Human Pathogens with Antibiotic resistance genes has shifted the focus towards the plant origin antimicrobial drugs with advanced nano-based methods. Screening of phytochemical components is done using various biochemical methods. UVvisible spectrophotometer is utilized to determine the silver Nanoparticle's size, shape, and its stable nature in the aqueous colloidal solution. FT-IR spectral analysis to identify the bio molecules responsible for the reduction of Ag+ ions. The extracts of Carica papaya leaves were found to be rich in Vitamins, Phenols, Proteolytic enzymes which acts as excellent Antimicrobial agent. Antibacterial activity of crude extracts and silver Nanoparticles synthesized from Carica papaya leaves was evaluated against chosen clinical isolates, which shows the effective zone of inhibition lesser side effects. Though crude extract has shown significant results, silver nanoparticles synthesized using specific key phytochemical component would have the better inhibiting capacity.


2017 ◽  
Vol 6 (7) ◽  
pp. 5441 ◽  
Author(s):  
Geetha Venugopal

In the present study, Psidium guajava leaves were taken for synthesizing silver nanoparticles and checked their antibacterial activity against E.coli, Klebsiella, Pseudomonas, Staphylococcus and Acinetobacter. The plant extract was analysed for the detection of the presence of protein, carbohydrate, flavonoids, terpenoids, glycosides, steroids, saponins, phenols and tannins. In this present study, the antibacterial activity of green synthesized silver nanoparticles from guava leaf shows the zone of inhibition against all the five pathogens.


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