Searching for enhanced iron fortification of formula milk via nanoparticles and Isotope Pattern Deconvolution

2018 ◽  
Vol 148 ◽  
pp. 165-171 ◽  
Author(s):  
Sonia Fernández-Menéndez ◽  
Rafaella Regina Alves Peixoto ◽  
Belén Fernández-Colomer ◽  
Marta Costa Romero ◽  
Alfredo Sanz-Medel ◽  
...  
Keyword(s):  
Iron Fortification ◽  
Formula Milk ◽  
Isotope Pattern

Speciation and isotope pattern deconvolution for inductively coupled plasma-mass spectrometry quantitative studies of mineral metabolism and supplementation

2010 ◽  
Vol 82 (2) ◽  
pp. 447-460 ◽  
Author(s):  
Alfredo Sanz-Medel ◽  
Maria Luisa Fernández-Sánchez ◽  
Héctor González Iglesias ◽  
José Blas López-Sastre
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Mineral Metabolism ◽  
Speciation Analysis ◽  
Human Breast Milk ◽  
Formula Milk ◽  
Inductively Coupled ◽  
Isotope Pattern ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

Human breast milk can be considered as “ideal” food for the correct development of newborn babies and, for those that are not breast-fed, formula milk has to be used instead. Ideally, the composition of such formula milk preparations should closely resemble that of maternal human milk. Considerable differences between both in the total content of trace elements such as Fe, Cu, Se, Zn, and I and in their chemical form in both milk types have been demonstrated. Speciation analysis in milk whey was carried out first by high-performance liquid chromatography (HPLC) with inductively coupled plasma-mass spectrometry (ICP-MS) elemental detection and showed that the observed element distribution patterns were very different in the investigated human and formula milks. Using complementary molecular mass techniques (i.e., MALDI-TOF), the identity and chemical characterization of some biomolecules (e.g., protein) with which metals are associated in each fraction was also established (by a typical heteroatom-tagged proteomics protocol). Attempts to assess the nutritional value of elemental supplements in formula milk with the aid of quantitative chemical speciation, using stable isotopes in combination with ICP-MS and isotope pattern deconvolution (IPD), proved to be successful to differentiate and quantify endogenous (natural) and exogenous (supplemented) Se or Fe trace levels. In particular, the application of such ICP-MS based techniques to study Se bioavailability from formula milk and metabolism in Se-supplemented lactating rats is discussed in detail. Quantification of selenospecies of endogenous (natural) and exogenous (supplement) Se in rat’s urine is demonstrated and relevant information on possible Se biotransformations and its final catabolism from such results is discussed.

Across The “Sweetiest” Properties Of Human Breast Milk: Focus On Oligosaccharides

2020 ◽  
Vol 16 ◽  
Author(s):  
Flaminia Bardanzellu ◽  
Alessandra Reali ◽  
Maria Antonietta Marcialis ◽  
Vassilios Fanos
Keyword(s):  
Breast Milk ◽  
Active Role ◽  
Individual Variability ◽  
Human Breast Milk ◽  
Formula Milk ◽  
Target Organs ◽  
Lactating Mothers ◽  
Neonatal Nutrition ◽  
Genetic And Environmental Factors ◽  
Systemic Infections

Introduction: Breast Milk (BM), containing nutrients and bioactive components, represents the best source for neonatal nutrition and determines short- and long- term benefits. Human milk oligosaccharides (HMOs) play an active role in these pathophysiological mechanisms. In fact; they influence the shaping of breastfed infant’s gut microbiota, promote intestinal development, confer protection against intestinal or systemic infections modulating immune system; moreover, HMOs determine extra-intestinal effects on several target organs, i.e reducing necrotizing enterocolitis rate or improving brain development. Aims: In this review, we analyze the great inter- and intra-individual variability of BM HMOs, investigating maternal, genetic and environmental factors modulating their composition. Moreover, we provide an update regarding HMOs’ unique properties, underlining their complex interaction with intestinal microbiota and host-derived metabolites. The possible HMOs’ influence on extra-intestinal bacterial communities, potentially influencing newborns’ and even lactating mothers’ health, have been hypothesized. Finally, recognized HMOs’ crucial role, we underline the promising opportunities showed by their addition in formula milk, useful to create dairy products more similar to maternal milk itself.

Levels of Trace Elements in Human Breast Milk in Jordan: a Comparison with Infant Formula Milk Powder

2021 ◽  
Author(s):  
Yahya R. Tahboub ◽  
Adnan M. Massadeh ◽  
Nihaya A. Al-sheyab ◽  
Diab El shrafat ◽  
Israa A. Nsserat
Keyword(s):  
Trace Elements ◽  
Breast Milk ◽  
Infant Formula ◽  
Milk Powder ◽  
Human Breast Milk ◽  
Human Breast ◽  
Formula Milk ◽  
Infant Formula Milk

scholarly journals Breastfeeding in Refugee Camps: A Child and Maternal Right?

2021 ◽  
Author(s):  
Aleisha Ebrahimi
Keyword(s):  
Human Rights ◽  
Best Interests ◽  
Refugee Camps ◽  
International Human Rights Law ◽  
Human Rights Law ◽  
Human Right ◽  
International Human Rights ◽  
Formula Milk ◽  
International Human ◽  
Milk Marketing

Abstract In recognition of the health benefits breastfeeding offers for both mother and child, breastfeeding has been acknowledged in various International Human Rights Law instruments. Furthermore, against the backdrop of aggressive formula milk marketing campaigns, significant soft law provisions contained within the International Code of Marketing of Breast-milk Substitutes 1981 regulate and control the promotion of breastmilk substitutes. Refugee camps, however, remain aligned with pre-code practice, as formula milk is often one of the first donations to arrive in camps. Mothers, who are still affected by historical formula marketing campaigns, receive formula milk and perceive its availability and distribution as an endorsement over breastfeeding. In this article, International Human Rights Law is analysed, within the framework of the principle of the best interests of the child, to determine if the choice to breastfeed should be protected as a human right and how the indiscriminate supply of formula milk interacts with this choice in refugee camps.

scholarly journals Magnetron Sputtering Thin Films as Tool to Detect Triclosan in Infant Formula Powder: Electronic Tongue Approach

Coatings ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 336
Author(s):  
Cátia Magro ◽  
Margarida Sardinha ◽  
Paulo A. Ribeiro ◽  
Maria Raposo ◽  
Susana Sério
Keyword(s):  
Thin Films ◽  
Infant Formula ◽  
Tap Water ◽  
Milk Powder ◽  
Electronic Tongue ◽  
Principal Component ◽  
Formula Milk ◽  
Straight Line ◽  
Multi Walled Carbon Nanotubes ◽  
Walled Carbon Nanotubes

Triclosan (TCS) is being detected in breast milk and in infants of puerperal women. The harmful effects caused by this compound on living beings are now critical and thus it is pivotal find new tools to TCS monitoring. In the present study, an electronic tongue (e-tongue) device comprising an array of sputtered thin films based on Multi-Walled Carbon Nanotubes and titanium dioxide was developed to identify TCS concentrations, from 10−15 to 10−5 M, in both water and milk-based solutions. Impedance spectroscopy was used for device signal transducing and data was analyzed by principal component analysis (PCA). The e-tongue revealed to be able to distinguish water from milk-based matrices through the two Principal Components (PC1 and PC2), which represented 67.3% of the total variance. The PC1 values of infant formula milk powder prepared with tap water (MT) or mineral water (MMW) follows a similar exponential decay curve when plotted with the logarithm of concentration. Therefore, considering the TCS concentration range between 1015 and 10−9 M, the PC1 values are fitted by a straight line and values of −1.9 ± 0.2 and of 7.6 × 10−16 M were calculated for the sensor sensitivity and sensor resolution, respectively. Additionally, a strong correlation (R = 0.96) between MT and MMW PC1 data was found. These results have shown that the proposed device corresponds to a promisor method for the detection of TCS in milk-based solutions.

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