scholarly journals The relationship between major polyphenolic acids and stigmasterol to antioxidant activity in different extracts of Myrmecodia platytyrea

2018 ◽  
Vol 115 ◽  
pp. 94-99 ◽  
Author(s):  
S. Agatonovic-Kustrin ◽  
D.W. Morton ◽  
H.H. Mizaton ◽  
H. Zakaria
Keyword(s):  
Antioxidant Activity ◽  
The Relationship ◽  
Polyphenolic Acids

Statistical Analysis of the Relationship Between Antioxidant Activity and the Structure of Flavonoid Compounds

2019 ◽  
Vol 70 (9) ◽  
pp. 3103-3107 ◽  
Author(s):  
Ioana Glevitzky ◽  
Gabriela Alina Dumitrel ◽  
Mirel Glevitzky ◽  
Bianca Pasca ◽  
Pavel Otrisal ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Activities ◽  
Basic Structure ◽  
Oh Groups ◽  
Flavonoid Compounds ◽  
Chi Squared ◽  
Potential Link ◽  
Van Der Waals Surface ◽  
The Relationship ◽  
Phenolic Oh Groups

Using different methods of statistics, this paper aims to highlight the potential link between the antioxidant activity of flavonoids and the corresponding molecular descriptors. By calculating the descriptors (van der Waals surface (A), molar volume (V), partition coefficient (LogP), refractivity (R), polarizability (a), forming heat (Hformation), hydration energy (Ehidr), the dipole moment (mt)), together with antioxidant activities (RSA) calculated or taken from the literature, number of phenolic -OH groups and the presence (2) or absence (1) of C2=C3 double bond) for 29 flavonoid compounds and by intercorrelation between the studied parameters, the link between the number of phenolic groups grafted to the basic structure of flavonoids and their antioxidant activity was confirmed. Simultaneously, by using the chi-squared test and the intercorrelations matrix, a satisfactorily correlation coefficient (r2=0.5678; r=0.7536) between the structure of the flavonoids and their activity was obtained, fact that confirms the correlation of the antioxidant activity with the number of -OH phenolic groups.

PROSPECTS FOR USING ASTRAGALUS ONOBRYCHIS AS A SOURCE OF NATURAL ANTIOXIDANTS

2021 ◽  
pp. 47-53
Author(s):  
Pozdnyakovа Т.А. ◽  
Kuleshovа Е.S. ◽  
Bubenchikov R.A.
Keyword(s):  
Antioxidant Activity ◽  
Free Radicals ◽  
Chemical Interaction ◽  
Raw Materials ◽  
Natural Antioxidants ◽  
The Body ◽  
Plant Raw Materials ◽  
Total Antioxidant ◽  
Promising Source ◽  
The Relationship

The predominance of synthetic and genetically modified foods in the diet of a modern person often leads to disruption of natural metabolic processes and the accumulation of toxic free radicals in the body, which provokes the development of various diseases. Natural antioxidants from medicinal plants can help maintain health and stop the processes of peroxidation. In our opinion, Аstragalus onobrychis can become a promising source of natural antioxidants. The aim of this study was to establish the antioxidant activity in extracts from the herb Astragalus onobrychis. In order to obtain objective and reliable results during our research, we used two methods: the method of titrimetry and spectrophotometry of free radicals. The titrimetric method is based on the chemical interaction between an oxidizing agent (potassium permanganate) and natural antioxidants present in extracts from plant raw materials, since they exhibit the properties of reducing agents. The spectrophotometric method makes it possible to assess the value of antioxidant activity and the duration of the reaction by assessing the interaction of 2,2-diphenyl-1-picrylhydrazil with plant antioxidants. To establish the relationship between the antioxidant activity and the presence of phenolic compounds in the plant, the content of flavonoids and hydroxycinnamic acids in the herb Astragalus onobrychis was determined. As a result of the studies, the total antioxidant activity of extracts from the herb Astragalus onobrychis was established and it was revealed that its value depends on the type of extractant used, since this factor is associated with the content of various groups of natural antioxidants in the extraction. The data obtained indicate the prospects of using the herb Astragalus onobrychis as a source of natural antioxidants.

scholarly journals Chemometrics Application for Grouping and Determinating Volatile Compound which related to Antioxidant Activity of Turmeric Essential Oil (Curcuma longa L)

2020 ◽  
pp. 1
Author(s):  
Rosy Islamadina ◽  
Adelin Can ◽  
Abdul Rohman
Keyword(s):  
Antioxidant Activity ◽  
Essential Oil ◽  
Curcuma Longa ◽  
Principal Component ◽  
Correlated Variables ◽  
And Cluster Analysis ◽  
The Relationship ◽  
Essential Oil Compounds ◽  
Chemical Contents

Turmeric essential oil is known to have antioxidant activity. Various in vitro antioxidantactivity assays has been carried out. Related to this research, it tries to examine the antioxidantpotential of turmeric essential oil and see the composition that is responsible for antioxidant activitycombine with chemometrics. The research method used was a narrative review of 60 articlesobtained from several databases. The review conducted on profiling essential oil compounds thatidentified using GC-MS and evaluation of the antioxidant activity of turmeric essential oil with themost commonly used method including scavenging radical 2,2 diphenyl-1-picrylhydrazyl (DPPH)and 2,2-azinobis (3-ethylbenzothiazoline-6 sulfonic acid (ABTS). Analysis methods used forgrouping various multivariate data subjects and determaining the relationship between thevariables were Principal Component Analysis (PCA) and Cluster Analysis (CA). According to thereview, turmeric essential oils are proven to have potential antioxidant activity and have variationsin chemical contents. PCA was success for grouping subjects with various correlated variables,determining variables wich the most influential and correlation between variables. CA method canbe used to group samples without requiring mutually correlated variables.

scholarly journals Antioxidant and the Dwarfing Candidate Gene of “Nantongxiaofangshi” (Diospyros kaki Thunb.)

2019 ◽  
Vol 2019 ◽  
pp. 1-14
Author(s):  
Yuhan Dong ◽  
Peihong Wang ◽  
Mengting Jiang ◽  
Shenchun Qu
Keyword(s):  
Antioxidant Activity ◽  
Functional Role ◽  
Growth Inhibitor ◽  
Signal Transduction Pathways ◽  
Diospyros Kaki ◽  
Phenological Stages ◽  
Related Research ◽  
Plant Growth Inhibitor ◽  
The Relationship

The aims of this work were to identify genes related to dwarfing for subsequent dwarfing-related research in persimmon and evaluate the relationship between antioxidant activity, dwarf, and hormones of persimmon trees for analyzing the possible dwarf mechanism oxidation factors. In the present study, a transcriptome analysis of “Nantongxiaofangshi” was used to identify and clone 22 candidate genes related to gibberellin signal transduction pathways and synthetic pathway. The expression of these genes was assessed in two persimmon cultivars, “Dafangshi” and “Nantongxiaofangshi,” by RT-qPCR at different phenological stages and in response to the exogenous application of GA3 (GA treatment) and PAZ (paclobutrazol, a plant growth inhibitor, also called PP333). The results revealed differential expression of 14 of these 22 genes in the two varieties. Subsequently, endogenous hormone levels were assessed of the two varieties, along with the number of internodes and internode length. The results suggested that the persimmon could be used as a valuable and powerful natural candidate for providing information on the functional role of dwarfing.

scholarly journals Antioxidant Activity of Metabolites from Coleonema Album (Rutaceae)

2006 ◽  
Vol 1 (5) ◽  
pp. 1934578X0600100 ◽  
Author(s):  
Lindy L. Esterhuizen ◽  
Riaan Meyer ◽  
Ian A. Dubery
Keyword(s):  
Antioxidant Activity ◽  
South African ◽  
Structural Information ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Active Components ◽  
Bioassay Guided Fractionation ◽  
The Relationship

Coleonema album, a member of the South African ‘Fynbos’ biome, was evaluated for its antioxidant and free radical scavenging activity. Ethanol- and acetone-based extracts from plant material obtained from two different geographical areas were analysed. A bioassay-guided fractionation methodology was followed for screening of active compounds. The 1,1-diphenyl-2-picrylhydrazyl (DPPH)-TLC method revealed the presence of a number of antioxidants which were quantified by the DPPH-spectrophotometric assay and the oxygen radical absorbance capacity (ORAC) assay. The C. album extracts possessed significant in vitro antioxidant activity, a large portion of which appeared to be contributed by the phenolic compounds. In contrast, the reducing power of the extracts could not be correlated with the observed antioxidant activity. Identification and structural information of the active components were obtained by a combination of preparative TLC and LC-MS which revealed the presence of coumarin aglycones and glycosides. The results of this study indicate that C. album contains strong antioxidants that warrant further investigation into the relationship between the structure and activity of the active coumarin metabolites.

scholarly journals Phytochemical Profile and Antioxidant Activity of Aerial and Underground Parts of Salvia bulleyana Diels. Plants

Metabolites ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 497
Author(s):  
Izabela Grzegorczyk-Karolak ◽  
Marta Krzemińska ◽  
Anna K. Kiss ◽  
Monika A. Olszewska ◽  
Aleksandra Owczarek
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Liquid Chromatography ◽  
Rosmarinic Acid ◽  
Root Extract ◽  
Ionization Mass ◽  
Antioxidant Power ◽  
Salvianolic Acid ◽  
Promising Source ◽  
Polyphenolic Acids

Plants have been used for medical purposes since ancient times. However, a detailed analysis of their biological properties and their associated active compounds is needed to justify their therapeutic use in modern medicine. The aim of the study was to identify and quantify the phenolics present in hydromethanolic extracts of the roots and shoots of the Chinese Salvia species, Salvia bulleyana. The qualitative and quantitative analyses were carried out by ultrahigh-performance liquid chromatography with electrospray ionization mass spectrometry detection (UHPLC-PDA-ESI-MS), and high-performance liquid chromatography with photodiode array (HPLC-PDA) detection. The extracts of S. bulleyana were also screened for their antioxidant activity using ferric ion (Fe3+) reducing antioxidant power (FRAP), 1,1-diphenyl-2-picrylhydrazyl (DPPH), diammonium 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonate) cation (ABTS), superoxide radical anion (O2•–), and inhibition of lipid peroxidation assays. The S. bulleyana extracts were found to contain 38 substances, of which 36 were phenols, with a total level of 14.4 mg/g DW (dry weight) in shoots, and 23.1 mg/g DW in roots. Twenty-eight phenols were polyphenolic acids or their derivatives, the most abundant in shoots being rosmarinic acid, and in roots, salvianolic acid K followed by rosmarinic acid. The other major phenolic acids were caffeic acid, caffeoyl-threonic acids, isomers of lithospermic acid, salvianolic acid F, salvianolic acid B, and yunnaneic acid E. In addition to polyphenolic acids, nine flavonoids were detected in the shoot extract. While both extracts showed significant antioxidant activity, the shoot extract, containing both polyphenolic acids and flavonoids, demonstrated a slightly greater antioxidant potential in some of the anti-radical tests than the roots. However, the root extract proved to be slightly more effective in the lipid peroxidation inhibition test. Thus, S. bulleyana was demonstrated as a promising source of antioxidants, and worthy of further more detailed studies.

scholarly journals Total antioxidant activity of low density lipoproteins and the relationship with α-tocopherol status

FEBS Letters ◽  
1995 ◽  
Vol 365 (2-3) ◽  
pp. 164-166 ◽  
Author(s):  
Nicholas J. Miller ◽  
George Paganga ◽  
Sheila Wiseman ◽  
Wim Van Nielen ◽  
Lilian Tijburg ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Low Density Lipoproteins ◽  
Low Density ◽  
Total Antioxidant Activity ◽  
Total Antioxidant ◽  
The Relationship

scholarly journals The Relationship between Antioxidant Activity and Total Phenolic Content in Cereals and Legumes

2015 ◽  
Vol 8 (3) ◽  
pp. 173-179 ◽  
Author(s):  
Yu-Wei Luo ◽  
Qian Wang ◽  
Jing Li ◽  
Xiao-Xiao Jin ◽  
Zhen-Ping Hao
Keyword(s):  
Antioxidant Activity ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Total Phenolic ◽  
The Relationship

scholarly journals Total Flavonoid Content and Antioxidant Activity of Temu Mangga (Curcuma mangga Val. & Zijp) and its Classification with Chemometrics

2020 ◽  
pp. 4
Author(s):  
Yuniar Intan Hartono ◽  
Indah Widyastuti ◽  
Hanna Zaidah Luthfah ◽  
Rosy Islamadina ◽  
Adelin Theresia Can ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Methanolic Extract ◽  
Antioxidant Activities ◽  
Total Flavonoid ◽  
Total Flavonoid Content ◽  
Flavonoid Content ◽  
The Relationship ◽  
Phenolic And Flavonoid ◽  
Phenolic And Flavonoid Compounds

Indonesia is a rich country in terms of its biodiversity. Herbs that are widely used tomaintain a healthy body comes from the Zingiberaceae family, including temu mangga. Temu mangga(Curcuma mangga Val. & Zijp) is effective for relieving gastric pain, diarrhea, menstrual pain, acneand ulcers, and increasing appetite. Besides, temu mangga is considered to have antioxidant activitydue to the presence of the phenolic and flavonoid compounds. This study aims to determine thecorrelation and classification of temu mangga from various places based on total flavonoid contentand antioxidant activities. The samples were extracted with methanol, then tested for totalflavonoid content by AlCl3 method and antioxidant activity by DPPH free radical capture method.Analysis was performed using correlation coefficient value and chemometrics PCA (PrincipalComponent Analysis) and CA (Cluster Analysis) to see the relationship between total flavonoidcontent with their antioxidant activity and to see their classification. Total flavonoid content ofmethanolic extract of temu mangga gives a moderate correlation to its antioxidant activity with r =-0.6085 and clustering samples successfully determined by PCA and CA which resulted in 4 groups.Keywords: Curcuma mangga Val. & Zijp, Methanolic Extract, Flavonoid, Antioxidant, PCA, CA

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