Psychiatric Assessment of Anxiety and Depression in Medical Patient

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
D. Telles-Correia ◽  
A. Barbosa ◽  
I. Mega

Anxiety and depression are very common in patients with medical illness and can be associated to a reduction in quality of life and a poor clinical evolution.The actual concept of anxiety is based on many theoretical models as Goldstein's anxiety model, State/trate anxiety model, Lazarus' transactional stress model. The concept of depression is based on models such as Beck's Cognitive Model and Seligman's learned helplessness model of depression.The link between anxiety/depression and medical illness can be of two kinds: biological (immunological, neuroendocrine, inflammatory systems) and behavioural (coping strategies, adherence to medical advice and prescription, etc).A dimensional approach should be used to access anxiety and depression in medical once the thresholds of depression and anxiety that are associated with medical outcomes are not known.Both self report and rating scale/interview measurements have certain advantages as well as certain inherent disadvantages. Neither approach is universally better than other.Some of the most used instruments are Hamilton Anxiety Scale (HAM), Hamilton Depression Scale (HDS), Montgomery and Asberg Depression Rating Scale (MADRS), Hospital Anxiety and Depression Scale (HADS), Beck Depression Inventory (BDI), and State Trait Anxiety Inventory (STAI).The only scale validated exclusively to access depression and anxiety in medical population, and that can overcome the influence that medical disease has in depression and anxiety is HADS.

2019 ◽  
Vol 28 (1) ◽  
pp. 49-59
Author(s):  
Sanchary Prativa ◽  
Farah Deeba

This study aimed at examining the relationship between parenting styles and depression in adolescents. Convenient sampling was used to collect 100 adolescents (Mean age = 15.25 years, Sd = 0.90) from two colleges of Dhaka city, Bangladesh. Parental Attitude Questionnaire (PAQ) was used to measure parenting styles and two other self-report measures, Hospital Anxiety and Depression Scale (HADS) and Short Mood and Feelings Questionnaire (SMFQ) were used to assess depression in adolescents. From multiple regression analysis significant relationship was found between parenting style and adolescents’ depression measured by one self-rating scale. The overall regression model for investigating the relationship between parenting style and depression in adolescent was significant with HADS, (F = 3.77, p = 0.007) but not significant with SMFQ scores (F = 0.880, p = 0.454). For the dependent variable of depression measured by HADS, the strongest predictors were authoritative parenting style (β = –0.28, p = 0.03) and monthly income of the family which is also significant (β = 0.25, p = 0.01). Implications of the findings for child rearing and research are discussed. Dhaka Univ. J. Biol. Sci. 28(1): 49-59, 2019 (January)


2007 ◽  
Vol 101 (1) ◽  
pp. 291-301 ◽  
Author(s):  
Ana Luiza Camozzato ◽  
Maria Paz Hidalgo ◽  
Sônia Souza ◽  
Márcia L. F. Chaves

The association among items of the self-reported version of the Hamilton Depression Scale (Carroll Rating Scale), answered according to a memory of a maximally disturbing event experienced, and respondents' sex was examined in a nonclinical sample of 320 college students, 164 women ( M age = 21.7 yr., SD = 3.6) and 156 men ( M age = 23.5 yr., SD = 5.8). An assessment of sex bias was also evaluated. Multiple regression analysis showed that statements regarding unhappiness, urge to cry, dizziness and faintness, and waking in the middle of the night were significantly associated with women. Removal of these items from the Carroll Rating Scale Total scores eliminated the sex differences in depression rates. Items that displayed significant sex bias were those regarding behavior and emotions commonly attributed to women within the general population.


2021 ◽  
Vol 12 ◽  
Author(s):  
Chun-Yan Yang ◽  
Hong-Jiao Xu ◽  
Shan-Shan Liu ◽  
Yue-Jing Wu ◽  
Yun Long ◽  
...  

Background: In China, intergenerational rearing is a ubiquitous phenomenon based on unique national conditions. This study aimed to explore family dynamics in intergenerational rearing families as well as their correlation with older household members' anxiety and depression.Methods: The elderly from intergenerational (n = 141) and non-intergenerational rearing families (n = 266) were investigated using the following scales: the general information questionnaire, Self-Rating Scale of Systemic Family Dynamics, Geriatric Depression Scale, and Self-Rating Anxiety Scale.Results: Scores from the four dimensions (family atmosphere, system logic, individuation, and the concept of disease) of the structure of family dynamics were computed. The comparison of these dimensions scores and the total scores of grandparents' anxiety and depression for the two groups were not statistically significant (p > 0.05). In Pearson's correlation analysis, no significant correlation between the family atmosphere dimension and the total score of the grandparents' depression and anxiety scales was observed. The system logic aspect was negatively correlated with depression and anxiety scale scores. The individual dimension was positively correlated with the anxiety scale scores. The disease concept dimension was positively correlated with depression and anxiety scale scores. Hence, the results were statistically significant.Conclusion: There were no significant differences in terms of family dynamics and risk of anxiety and depression among grandparents between the two family types. The system logic, individuation, and disease concept dimensions were correlated with their anxiety and depression.


2000 ◽  
Vol 45 (4) ◽  
pp. 357-362 ◽  
Author(s):  
Jack Haggarty ◽  
Zack Cernovsky ◽  
Patricia Kermeen ◽  
Harold Merskey

Objective: To determine the rates of depression, anxiety, and alcohol abuse, using modern nosology, in a random sample of residents aged 14 to 85 years living in an Arctic community. Method: A cross-sectional 2-step survey of randomly selected households was undertaken, using a self-report questionnaire to screen for anxiety, depression, and alcohol abuse. The survey included the Hospital Anxiety and Depression Scale (HADS) and Ewing and Roose's 4-question alcohol screening instrument (the CAGE questionnaire). Cut-off scores for the HADS and CAGE were found by comparing HADS and CAGE scores with scores on the Structured Clinical Interview for the DSM-III-R (SCID) in a stratified subs ample. Results: Estimated rates of depression and anxiety were 26.5% and 19.0% respectively within the past week, and estimated rates of lifetime alcohol abuse were 30.5%. Conclusions: The estimated prevalence of psychiatric disorders in this Arctic community is higher than that indicated in previous findings on Native mental health.


2016 ◽  
Vol 20 (12) ◽  
pp. 1039-1046 ◽  
Author(s):  
Katie Grogan ◽  
Jessica Bramham

Objective: Given that the diagnosis of adulthood ADHD depends on the retrospective self-report of childhood ADHD symptoms, this study aimed to establish whether current mood affects the accuracy of retrospective self-ratings of childhood ADHD. Method: Barkley’s Adult ADHD Rating Scale (BAARS) was used to assess the retrospective self- and parent-reports of childhood ADHD symptoms of 160 adults with ADHD and 92 adults without ADHD. Self-rated current mood was also measured using the Hospital Anxiety and Depression Scale (HADS). Results: Higher BAARS self-ratings correlated with higher HADS self-ratings. Strongest correlations were evident between hyperactive/impulsive symptoms and anxiety symptoms. There was no relationship between current mood and accuracy of self-report. Conclusion: Current mood does not affect the accuracy of retrospective self-ratings of ADHD. Future research should aim to provide new measures of anxiety in ADHD to avoid the double counting of hyperactive/impulsive and anxiety symptoms.


2021 ◽  
Vol 5 (10) ◽  
pp. 648-653
Author(s):  
O.V. Kotova ◽  
◽  
A.A. Belyaev ◽  
E.S. Akarachkova ◽  
◽  
...  

Depressive disorder, or depression, is one of the most common psychiatric diseases affecting millions worldwide. Anxiety disorders are also common. Most patients with anxiety refer to general practitioners with the signs of vegetative dysfunction. Anxiety per se occurs in 40% and is associated with depression (mixed anxiety-depressive disorder) IN 26%. Comorbidity of anxiety and depression is relatively high, and the extent of this comorbidity changes with aging. This paper reviews diagnostic and treatment modalities for anxiety and depression. Their diagnosis includes clinical examination and questionnaire. This paper describes Neuro Scanner, an application that includes four scales to diagnose anxiety and depression, i.e., the Veyn Scale, Spielberg Trait Anxiety scale, Hospital Anxiety and Depression Scale (HADS), and Montgomery–Asberg Depression Rating Scale (MADRS). To date, a large amount of data illustrating a significant genetic, neurobiological, and symptomatic similarity of depression and anxiety has been accumulated. This phenomenon accounts for the efficacy of the same drugs (e.g., antidepressants, anxiolytics, neuroleptics, etc.). KEYWORDS: anxiety, depression, comorbidity, anhedonia, diagnosis, Neuro Scanner, anti-depressants, anxiolytics, cognitive behavioral therapy. FOR CITATION: Kotova O.V., Belyaev A.A., Akarachkova E.S. State-of-the-art diagnostic and treatment modalities for anxiety and depression. Russian Medical Inquiry. 2021;5(10):648–653 (in Russ.). DOI: 10.32364/2587-6821-2021-5-10-648-653.


2017 ◽  
Vol 41 (S1) ◽  
pp. S3-S4
Author(s):  
J. Rabinowitz

Response to antidepressants in major depressive disorder is highly variable and determinants are not well understood. Presentation will provide clinical trial data on time to response and determinants of response to antidepressant treatment. Data is from the Innovative Medicines Initiative funded NEWMEDS collaboration, a large public-private collaboration which assembled the largest dataset of individual patient level information from randomized placebo-controlled trials of antidepressant drugs. Studies were conducted by four large pharmaceutical companies. Dataset includes placebo-controlled trials of citalopram, duloxetine, escitalopram, quetiapine and sertraline in adults with MDD. We examined patient and trial-design-related determinants of outcome as measured by change on Hamilton Depression Scale or Montgomery–Asberg Depression Rating Scale in 34 placebo-controlled trials (drug, n = 8260; placebo, n = 3957). While it is conventional for trials to be 6–8 weeks long, data presented will show that drug-placebo differences were observable at week 4 with nearly the same sensitivity and lower dropout rates. Having any of these attributes was significantly associated with greater drug vs. placebo differences on symptom improvement: female, patients being middle aged, increasing proportion of patients on placebo, excluding all patients from centers with high placebo response regardless of active treatment response, using active run in periods and including self-report measures. Proof of concept trials can be shorter and efficiency improved by selecting enriched populations based on clinical and demographic variables, ensuring adequate balance of placebo patients, and carefully selecting and monitoring centers. In addition to improving drug discovery, patient exposure to placebo and experimental treatments can be reduced.Disclosure of interestI have received research grant(s) support and/or travel support and/or speaker fees and/or consultant fees from Takeda, Minerva, Intra-cellular Therapies, Janssen (J&J), Eli Lilly, Pfizer, BiolineRx, Roche, Abraham Pharmaceuticals, Pierre Fabre, Minerva and Amgen.


PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248314
Author(s):  
Yu-Ting Wu ◽  
Wan-Yu Huang ◽  
Chew-Teng Kor ◽  
Ko-Hung Liu ◽  
Ting-Yu Chen ◽  
...  

Introduction Studies on the association between adiponectin and leptin and anxiety and depression among postmenopausal women are limited. Therefore, the present study specifically evaluates the mutual relationships between adiponectin and leptin and anxiety and depression in postmenopausal women. Participants and design In this cross-sectional study, a total of 190 women aged 40–65 years were enrolled. Depression symptoms were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D), and anxiety symptoms were evaluated using the Hamilton Anxiety Rating Scale (HAM-A). Fasting specimens were collected to measure sex hormone, glucose, insulin, and adipokine levels. Multiple linear regression analysis was performed to evaluate the associations between depression and anxiety and adipocyte-derived hormones. Settings The study was performed in a hospital medical center. Results Among 190 enrolled postmenopausal women, Spearman’s rank correlation analysis revealed significant correlations between CES-D and HAM-A (r = 0.715, P < 0.0001), between CES-D and adiponectin (p = 0.009) and leptin (p = 0.015), and between HAM-A and adiponectin (p = 0.01) and leptin (p = 0.001). The subjects with CES-D ≥ 16 and with HAM-A ≥ 18 had higher adiponectin levels than those with CES-D < 16 and HAM-A < 18, respectively. After adjusting for age, body mass index, exercise, alanine amino transferase and parameters of lipid profiles, Log adiponectin levels were found to be significantly associated with both CES-D and HAM-A, and Log leptin levels were only significantly associated with HAM-A. Conclusions The data show that adiponectin and leptin levels are significantly associated with depression and anxiety symptoms. These results suggest that higher adiponectin and lower leptin levels may serve as potential markers related to anxiety and mood in postmenopausal women. More future research that is designed to deal with the important confounders (e.g., population heterogeneity) is needed to investigate comprehensively on these associations.


2021 ◽  
Vol 26 (2) ◽  
pp. 367-380
Author(s):  
Teona Serafimova ◽  
Maria Loades ◽  
Daisy Gaunt ◽  
Esther Crawley

Background: One in three adolescents with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) have mental health problems. Multi-informant perspectives are key to psychological assessment. Understanding parent-child agreement is crucial to accurate diagnosis, particularly where severe fatigue limits self-report. Methods: Agreement on the revised children’s anxiety and depression scale (RCADs) was assessed between parents and children with CFS/ME ( n = 93) using Bland-Altman plots, cross tabulations and regression analyses. Results: Diagnostic thresholds were met more frequently based on child-report. Parent- and child-report had similar sensitivity and specificity on RCADS compared to gold-standard diagnostic interviews. Regression analysis found similar accuracy between both reports. For anxiety diagnoses, odds ratio (OR) for child-report was 1.10 (CI = 1.06–1.14), and 1.10 (CI = 1.05–1.14) for parent-report. For depression, OR for child report was 1.26 (CI = 1.11–1.43), while for parent-report is was 1.25 (CI = 1.10–1.41). For total score, OR for child-report was 1.10 (CI = 1.05–1.13) while OR for parent-report was 1.09 (CI = 1.05–1.13). Conclusions: Reasonable agreement was observed between parent- and child-report of mental health symptoms in paediatric CFS/ME. While parent-report can facilitate psychological evaluation in CFS/ME, this is not a substitute for a child’s own report.


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