Side effects of treatment and quality of life among patients with schizophrenia

2011 ◽  
Vol 26 (S2) ◽  
pp. 1450-1450
Author(s):  
J. Ben Thabet ◽  
I. Feki ◽  
R. Sallemi ◽  
J. Masmoudi ◽  
L. Zouari ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Negative Symptoms ◽  
Rating Scale ◽  
Treatment Compliance ◽  
University Hospital ◽  
Average Score ◽  
Treatment Side Effects ◽  
Impaired Quality

The aim of our study was to assess the treatment side effects and their implications on quality of life in a population of schizophrenic patients.We included 50 patients with schizophrenia treated at Hthe psychiatry department of the university hospital in Sfax (Tunisia). We used the PANSS, the UKU side effect rating scale and the SF-36 to assess, respectively, the severity of disease, the treatment side effects and the quality of life. The statistical analysis was carried out by software SPSS.The assessment of quality of life revealed a global average score of 59.11 and an alteration in 54% of patients. Impaired quality of life was significantly correlated with irregular follow-up (p = 0.02), bad treatment compliance (p = 0.016) and polytherapy (p = 0.024). The presence of side effects which affect either moderately or severely daily activity was significantly correlated with impaired quality of life (p = 0.007). The presence of side effects was correlated in a significant way with altered quality of life (p = 0,007).Our study showed a relatively high frequency of side effects of treatment in patients with schizophrenia. They were correlated with impaired quality of life. They are also factors of bad compliance. Reduction and prevention of side effects requires the use of atypical antipsychotics which are better tolerated and more active on negative symptoms. However, they pose the problem of high costs. But it must be noted here that the overall cost of disease is higher with conventional antipsychotics than with atypical ones.

scholarly journals Quality of life, symptoms and dietary habits in oncology outpatients with malnutrition: A cross-sectional study

2021 ◽  
Vol 38 (2) ◽  
Author(s):  
Mira Sonneborn-Papakostopoulos ◽  
Clara Dubois ◽  
Viktoria Mathies ◽  
Mara Heß ◽  
Nicole Erickson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
At Risk ◽  
Side Effects ◽  
Dietary Habits ◽  
Nutritional Assessment ◽  
Mini Nutritional Assessment ◽  
University Hospital ◽  
Cross Sectional ◽  
European Organization

AbstractCancer-related malnutrition has a high prevalence, reduces survival and increases side effects. The aim of this study was to assess oncology outpatients and risk of malnutrition. Reported symptoms and quality of life (QoL) in patients found to be at risk of malnutrition or malnourished were compared to patients without malnutrition. Using a standardized questionnaire, the European Organization for Research and Treatment of Cancer Questionnaire for Quality of Life and the Mini Nutritional Assessment (MNA), patients in an outpatient cancer clinic undergoing chemotherapy treatment at a German University Hospital were assessed for nutrition, risk of malnutrition and quality of life. Based on the MNA, 39 (45.9%) patients were categorized as malnourished or at risk for malnutrition. Loss of appetite (n = 37.6%, p < 0.001) and altered taste sensation (n = 30,3%, p < 0.001) were the symptoms most frequently associated with reduced food intake. Patients with risk of malnutrition scored lower on the global health status (n = 48.15%, p = 0.001). Side effects of cancer treatments lead to a higher risk of malnutrition and as a consequence lower QoL. These side effects should be addressed more efficiently in cancer care.

scholarly journals BIOBRAN MGN-3

2012 ◽  
Vol 20 (01) ◽  
pp. 13-16
Author(s):  
Ahmad Ijaz Masood ◽  
RABEETA SHEIKH ◽  
RANA ATIQUE ANWER
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Hair Loss ◽  
White Blood Cells ◽  
Food Supplement ◽  
Severe Nausea ◽  
Treatment Side Effects ◽  
Group A ◽  
Group B

Objective: The aim of study was to assess the effect of Biobran in reducing of chemotherapy induced side effects in termsof tiredness, anorexia, vomiting and hair loss and quality of life in terms of weight loss. Setting: Radiotherapy Department, NishtarHospital Multan. Material and Methods: Fifty patients of breast cancer were enrolled randomly in two groups. Group-A patients weregiven 3 gram dose of Biobran MGN-3 per day one week before and one week after chemotherapy. Group-B patient were givenchemotherapy alone. Total six cycles of chemotherapy were given. No multivitamin or food supplements were given during this study.Chemotherapy induced side effects (tiredness, anorexia, and vomiting, hair loss) were assessed by questionnaire to the patients beforestart of each cycle. Weight was checked before each cycle to assess weight gain or loss. White blood cells were checked by completeblood count just before and one week after chemotherapy. Results: Between six months, 50 patients were enrolled in RadiotherapyDepartment, Nishtar Hospital Multan. There was a significant reduction in tiredness and anorexia in group-A patients. 20 (80%) patients ofgroup-A felt increase in their diet and no tiredness without any appetizer or multivitamin. But group-B patients demanded for appetizer dueto severe anorexia after chemotherapy except 3 (12%) patients who didn’t use any appetizer or food supplement. In group-A, 15 (60%)patients didn’t need any anti-emetic as compared to group-B all patient (100%) experienced severe nausea during and afterchemotherapy. Group-A patients experienced less hair fall 7 (28%) patients as compared to other group which is 25 (100%) patients.Conclusions: The study showed that, by helping to optimize the immune system, Biobran MGN-3 can not only help maximize treatmentsuccess, but also minimize treatment side effects and improve quality of life during treatment and in recovery.

scholarly journals When Eating Becomes Torturous: Understanding Nutrition-Related Cancer Treatment Side Effects among Individuals with Cancer and Their Caregivers

Nutrients ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 356
Author(s):  
Brandy-Joe Milliron ◽  
Lora Packel ◽  
Dan Dychtwald ◽  
Cynthia Klobodu ◽  
Laura Pontiggia ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Cancer Treatment ◽  
Food Preferences ◽  
Treatment Side Effects ◽  
Food And Nutrition ◽  
Loss Of Appetite ◽  
Living With Cancer ◽  
Depth Interviews

Individuals living with cancer often experience multiple nutrition-related side effects from cancer treatment, including changes in taste and smell, nausea, diarrhea, loss of appetite, and pain during eating. These side effects can profoundly impact nutritional status and quality of life. The purpose of this study was to explore experiences with nutrition-related cancer treatment side effects among cancer patients and their family caregivers, the way they manage such side effects, and the resulting changes in food preferences and behaviors. Structured surveys and in-depth interviews were conducted. Interviews focused on the presence and management of treatment side effects, how those changes influenced food preferences, and the extent to which they interfered with quality of life. Most patients (72%) reported treatment side effects; 61% reported that these side effects impacted their eating and drinking. Common side effects included fatigue (58%), dry mouth (30%), nausea (24%), constipation (20%) and diarrhea (20%). Six overarching qualitative themes were identified: Spiral of side effects; Pain of eating; Burden of eating; Loss of taste/change in taste; Symptom management; and Solutions. The authors conclude with implications for food and nutrition practice—moving beyond traditional recommendations of what to eat or avoid—to consider the overall patient and caregiver experience.

scholarly journals Managing two decades of visceral leishmaniasis and HIV co-infection: a case report that illustrates the urgent research needs in the field

Sexual Health ◽  
2017 ◽  
Vol 14 (3) ◽  
pp. 286 ◽  
Author(s):  
Melissa L. Kelly ◽  
Angie N. Pinto ◽  
Dan Suan ◽  
Debbie Marriott ◽  
David A. Cooper ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Case Report ◽  
Side Effects ◽  
Visceral Leishmaniasis ◽  
Liver Failure ◽  
Infected Patient ◽  
Poor Quality ◽  
Research Needs ◽  
Treatment Side Effects

Visceral leishmaniasis and HIV co-infection presents diagnostic, monitoring and treatment challenges. This is a report of a co-infected patient who developed multiple complications and treatment side-effects, including renal and liver failure, pancytopenia with recurrent sepsis, along with anal cancer, depression and poor quality-of-life spanning over two decades. Urgent research specific to this cohort is needed.

Impact of Providing Audiotapes of Primary Adjuvant Treatment Consultations to Women With Breast Cancer: A Multisite, Randomized, Controlled Trial

2003 ◽  
Vol 21 (22) ◽  
pp. 4138-4144 ◽  
Author(s):  
Thomas F. Hack ◽  
Tom Pickles ◽  
Barry D. Bultz ◽  
J. Dean Ruether ◽  
Lorna M. Weir ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Patient Satisfaction ◽  
Side Effects ◽  
Adjuvant Treatment ◽  
Mood State ◽  
Controlled Trial ◽  
Information Provision ◽  
Average Score

Purpose: Women with breast cancer were provided with an audiotape of their primary adjuvant treatment consultation, and the following patient outcomes were measured at 12 weeks postconsultation: perceived degree of information provision, audiotape satisfaction and use, communication satisfaction with oncologist, mood state, and cancer-specific quality of life. Patients and Methods: Participants included 628 women newly diagnosed with breast cancer and 40 oncologists from six cancer centers in Canada. The patients were block randomized to one of four consultation groups: standard care control, not audiotaped; audiotaped, no audiotape given; audiotaped, patient given audiotape; and audiotaped, patient offered choice of receiving audiotape or not. Results: Patients receiving the consultation audiotape had significantly better recall of having discussed side effects of treatment than patients who did not receive the audiotape. Audiotape benefit was not significantly related to patient satisfaction with communication, mood state, or quality of life at 12 weeks postconsultation, and was not significantly affected by choice of receiving the audiotape. Patients rated the audiotape intervention positively, with an average score of 83.9 of 100. Conclusion: Audiotape provision benefits patients by facilitating their perception of being informed about treatment side effects, but does not significantly influence patient satisfaction with communication, mood state, or quality of life.

scholarly journals Quality of life and distress assessed with self and external assessment screening tools in patients with hematologic malignancies attending treatment in an acute hospital

2020 ◽  
Vol 29 (12) ◽  
pp. 3375-3385
Author(s):  
Bianca Senf ◽  
Kirsten Grabowski ◽  
Natascha Spielmann ◽  
Jens Fettel
Keyword(s):  
Quality Of Life ◽  
Rating Scale ◽  
Hematologic Malignancies ◽  
Self Report ◽  
Screening Tools ◽  
University Hospital ◽  
Screening Instruments ◽  
Treatment Needs ◽  
Close Link

Abstract Purpose In this study, we examined distress levels and quality of life (QoL) of patients with hematologic malignancies under treatment in an acute setting. We used external- and self-assessment instruments for distress. Additionally, we investigated the relation between distress and QoL as well as whether highly distressed patients differed from less distressed patients concerning their QoL. Methods A cross-sectional study with patients of the Medical Clinic II of the University Hospital Frankfurt was conducted. One hundred and nine patients were assessed with an expert rating scale and completed self-report questionnaires. Data were exploratively analyzed and group comparisons between patients who scored above the cut-off of the respective screening instruments and those who did not were conducted. Results Patients with hematologic malignancies experience high levels of distress and low QoL. Especially, role and social functioning are affected. Patients suffer most from fatigue, appetite loss, and insomnia. Using established cut-offs, all screening instruments were able to differentiate between patients regarding distress and QoL. Patients scoring above the cut-off were significantly more distressed and had a lower QoL. There was a medium-to-strong correlation between distress and QoL indicators. Conclusion Cancer-specific screening instruments seem to be able to identify treatment needs more specifically. They also allowed a better differentiation concerning QoL. The close link between distress and QoL needs to be recognized to enable a holistic approach to treatment and thereby optimize the quality of treatment.

Worry about quality of life for younger versus older adult thyroid cancer survivors.

2019 ◽  
Vol 37 (27_suppl) ◽  
pp. 157-157
Author(s):  
Stefanie Marie Thomas ◽  
David Reyes-Gastelum ◽  
Joel Milam ◽  
Kimberly Ann Miller ◽  
Anamara Ritt-Olson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Decision Making ◽  
Thyroid Cancer ◽  
Side Effects ◽  
Age Differences ◽  
Amount Of Information ◽  
Treatment Side Effects ◽  
Younger Age ◽  
Multivariable Analyses

157 Background: Thyroid cancer is one of the most common cancers in young adults, age 18-39 years. Since this population has distinct medical and developmental needs, it is important to understand age differences in worry about quality of life. Methods: Thyroid cancer patients diagnosed between 2014-15 were accrued from the Surveillance, Epidemiology and End Results Program (SEER) registries of Georgia and Los Angeles County and surveyed between 2017-18. The primary outcome was patient reported worry about quality of life. Covariates for this analysis included age (categorized 18-25, 26-39, 40-64, and 65-79), involvement in surgical decision making (low, just right, high) and amount of information received on treatment side effects (low, just right, high). Race/ethnicity, sex, and tumor characteristics were also evaluated. Multivariable analyses were used to assess associations between worry about quality of life and independent variables. Results: In the cohort of 2,632 patients, 39.8% were somewhat to very much worried about quality of life not being the same as before thyroid cancer diagnosis, 15.1% reported low involvement in surgical decision making, and 32.6% reported low amount of information regarding side effects. Younger age was associated with high worry about quality of life (p < 0.001), low involvement in decision making (p < 0.001) and low amount of information on treatment side effects (p < 0.001). In multivariable analyses, high worry was significantly associated with female sex (Odds ratio [OR]: 1.29 95% confidence Interval [CI]:1.04-1.59), non-white, non-Hispanic race/ethnicity (OR: 1.64 CI: 1.38-1.95), positive lymph nodes (OR: 1.41 CI: 1.14-1.75) and younger age (ages 18-25 years OR: 2.34 CI: 1.45-3.76; ages 26-39 years OR: 2.26 CI: 1.68-3.05; and ages 40-64 years OR:1.94 CI 1.50-2.51). Age differences remained significant after adding either involvement in decision-making or information received. Conclusions: Young adults report higher worry about quality of life. Controlling for decision-making involvement or information received about side effects did not eliminate age differences in worry. Ongoing psychosocial support addressing quality of life worries among younger survivors is needed.

scholarly journals ANALYSIS OF NON-CELIAC GLUTEN SENSITIVITY IN PATIENTS WITH ENDOMETRIOSIS

2021 ◽  
Vol 7 (5) ◽  
Author(s):  
Giulienny Maria Antunes Gonçalves ◽  
Eduardo Euzieres Granzotto ◽  
Renato Mitsunori Nisihara ◽  
Jan Pawel Andrade Pachnicki ◽  
Lucas Marin Dall’Stella, ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rating Scale ◽  
Instant Messaging ◽  
Average Score ◽  
Gastrointestinal Symptom Rating Scale ◽  
Informed Consent Form ◽  
Gastrointestinal Complaints ◽  
Relationship Of ◽  
The Impact

Overview and Aims: Identify patients with surgically confirmed endometriosis and with gastrointestinal symptomatology by assessing whether there is clinical improvement of these from the adoption of gluten-free diet (GFD). Study design: They were invited to participate in the study by the researchers through telephone calls and instant messaging applications after selection in the clinics of attending physicians. Population: Through the GSRS (Gastrointestinal Symptom Rating Scale) questionnaire, the relationship of GFD adherence to symptomatology attenuation and benefit in the quality of life of 48 patients was analyzed. Methods: Inclusion criteria: female patients with surgical confirmation of endometriosis who agreed to participate in the study in accordance with the Informed Consent Form (ICF). Exclusion criteria: patients who already performed GFD, patients diagnosed with celiac disease, gluten allergy or non-celiac sensitivity to gluten, presence of gastrointestinal comorbidities, severe diseases or cognitive alterations that prevented the study from being performed. The patients who obtained the top 20 scores were invited to adopt GFD for one month, among those selected, only 12 proposed to participate in the diet. However, three of these presented personal complications that prevented the continuation of the same. After this period, a new questionnaire was applied to measure the impact of the diet on quality of life. Results: Nine patients finished the proposed period for the diet, with the average score obtained in the pre-diet questionnaire reducing from 57.2 to 36 in the post-diet. Conclusion: There was an improvement in gastrointestinal complaints of most patients and consequently in quality of life with GFD.

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