scholarly journals Monitoring the effects of iodine prophylaxis in the adult population of southern Italy with deficient and sufficient iodine intake levels: a cross-sectional, epidemiological study

2017 ◽  
Vol 117 (1) ◽  
pp. 170-175 ◽  
Author(s):  
Daniela Bonofiglio ◽  
Stefania Catalano ◽  
Anna Perri ◽  
Marta Santoro ◽  
Lorenza Siciliano ◽  
...  

AbstractI prophylaxis is the most effective strategy to eradicate I deficiency disorders, but it has been shown to affect the thyroid disease pattern. In this study, we assessed the frequency of thyroid disorders in an adult population living in two areas of southern Italy after implementing I prophylaxis. To this aim, a cross-sectional, population-based study including 489 subjects from an I-deficient rural and an I-sufficient urban area of southern Italy was conducted. Thyroid ultrasound was performed on all participants, and urine and blood samples were collected from each subject. The levels of thyroid-stimulating hormone (TSH), thyroglobulin (TgAb) and thyroperoxidase antibodies (TPOAb), urinary I excretion (UIE), and thyroid volume and echogenicity were evaluated. We found that the median UIE was higher in the urban than in the rural area (P=0·004), whereas the prevalence of subjects affected by goitre was higher in the rural compared with the urban area (P=0·003). Positive TgAb rather than TPOAb were more frequent in subjects from the urban area compared with the rural area (P=0·009). The hypoechoic pattern at thyroid ultrasound (HT-US) was similar between the two areas, but TgAb were significantly higher (P=0·01) in HT-US subjects from the urban area. The frequency of elevated TSH did not differ between the two screened populations, and no changes were found for TgAb positivity in subjects with high TSH in the urban compared with the rural area. Our findings support that the small risks of I supplementation are far outweighed by the substantial benefits of correcting I deficiency, although continued monitoring of populations is necessary.

Author(s):  
Govind Maakhni ◽  
Shavinder Singh ◽  
Deepshikha Kamra

Background: In India, fast foods are becoming part of our daily lifestyle. Foods prepared in restaurants are very high in trans fats (TFs). Also, alarmingly about 400,000 tonnes of snacks, which are largely prepared in TFs are consumed every year. According to recent studies, TFs levels are 5 to 12 times higher in the oils consumed in India as compared to the world standard. The WHO recommends that TFs intake be less than 1 percent of total caloric intake. The objective of the study was to assess the consumption of TFs and fats in foods by the population in urban and rural areas.Methods: This was a community-based cross-sectional study. All adult females above 18 years of age who took an active part in kitchen were interviewed. Their dietary patterns were assessed. The sampling was done using a systematic random sampling technique and 200 participants each in rural and urban areas were selected.Results: 12 percent participants in the urban area and 9 percent participants in the rural area were exceeding WHO limit of less than 1 percent TFs consumption. The median value of TFs consumption was higher in urban area (0.575 grams/day) than in rural area (0.427 grams/day).Conclusions: The study concludes that 12 percent participants in the urban area and 9 percent participants in the rural area were exceeding TFs consumption. Therefore, a proactive approach to ensure that these WHO regulations have the full intended effect needs to be taken.


2021 ◽  
Author(s):  
Juanjuan zhang ◽  
Yeqing Gu ◽  
Ge Meng ◽  
Qing Zhang ◽  
Li Liu ◽  
...  

Abstract Background & AimsThe protective effect of onion against thyroid hypofunction has been reported in animal studies. However, in humans, the association between onion consumption and subclinical hypothyroidism are unclear. The study sought to explore the association between habitual onion intake and subclinical hypothyroidism among adult population from an iodine-replete area.ObjectiveWe aimed to investigate the relationship between dietary onion intake and subclinical hypothyroidism in Chinese populationMethodsA cross-sectional study (6,515 men and 5,290 women) was performed in Tianjin, China. Frequency of onion consumption was assessed using a valid self-administered food frequency questionnaire. Serum free triiodothyronine (FT3), free thyroxine (FT4), and thyroid-stimulating hormone (TSH) were determined by chemiluminescence immunoassay. Subclinical hypothyroidism was diagnosed with TSH >4.78 IU/mL. Multiple logistic regression was used to evaluate the association of onion intake with subclinical hypothyroidism.ResultsThe prevalence of subclinical hypothyroidism was 2.56% in men and 7.18% in women, respectively. In women, the fully adjusted odds ratios [95% confidence interval (CI)] of having subclinical hypothyroidism across increasing frequency of onion intake were 1.00 (reference) for <1 time/week, 0.99 (0.74-1.34) for 1-3 times/week, 0.73 (0.53-1.01) for 4-6 times/week, and 0.66 (0.46-0.95) for ≥7times/week (P for trend <0.01). However, we observed no significant association between onion intake and subclinical hypothyroidism in men. Stratified analyses suggested a potential effect modification by age; the odds ratios (95% CI) across extreme quartiles was 0.43 (0.20, 0.87) in <40 women and 1.05 (0.49, 2.28) in >60 women.ConclusionsFrequent consumption of onion is inversely associated with subclinical hypothyroidism in adult women from an iodine-replete area. Further studies are needed to explore the casual relationship.


2015 ◽  
Vol 42 (7) ◽  
pp. 622-631 ◽  
Author(s):  
Mario Aimetti ◽  
Stefano Perotto ◽  
Anna Castiglione ◽  
Giulia M. Mariani ◽  
Francesco Ferrarotti ◽  
...  

2007 ◽  
Vol 92 (3) ◽  
pp. 841-845 ◽  
Author(s):  
Bjørn O. Åsvold ◽  
Trine Bjøro ◽  
Tom I. L. Nilsen ◽  
Lars J. Vatten

Abstract Context: The association between thyroid function and blood pressure is insufficiently studied. Objective: The objective of the investigation was to study the association between TSH within the reference range and blood pressure. Design and Setting: This was a cross-sectional, population-based study. Subjects: A total of 30,728 individuals without previously known thyroid disease were studied. Main Outcome Measures: The main outcome measures were mean systolic and diastolic blood pressure and pulse pressure and odds ratio for hypertension (&gt;140/90 mm Hg or current or previous use of antihypertensive medication), according to categories of TSH. Results: Within the reference range of TSH (0.50–3.5 mU/liter), there was a linear increase in blood pressure with increasing TSH. The average increase in systolic blood pressure was 2.0 mm Hg [95% confidence interval (CI) 1.4–2.6 mm Hg] per milliunit per liter increase in TSH among men, and 1.8 mm Hg (95% CI 1.4–2.3 mm Hg) in women. The corresponding increase in diastolic blood pressure was 1.6 mm Hg (95% CI 1.2–2.0 mm Hg) in men and 1.1 mm Hg (95% CI 0.8–1.3 mm Hg) in women. Comparing TSH of 3.0–3.5 mU/liter (upper part of the reference) with TSH of 0.50–0.99 mU/liter (lower part of the reference), the odds ratio for hypertension was 1.98 (95% CI 1.56–2.53) in men and 1.23 (95% CI 1.04–1.46) in women. Conclusion: Within the reference range of TSH, we found a linear positive association between TSH and systolic and diastolic blood pressure that may have long-term implications for cardiovascular health.


Rheumatology ◽  
2020 ◽  
Vol 59 (9) ◽  
pp. 2556-2562 ◽  
Author(s):  
Raúl Cortés Verdú ◽  
José M Pego-Reigosa ◽  
Daniel Seoane-Mato ◽  
Mercedes Morcillo Valle ◽  
Deseada Palma Sánchez ◽  
...  

Abstract Objectives Prevalence of SLE varies among studies, being influenced by study design, geographical area and ethnicity. Data about the prevalence of SLE in Spain are scarce. In the EPISER2016 study, promoted by the Spanish Society of Rheumatology, the prevalence estimate of SLE in the general adult population in Spain has been updated and its association with sociodemographic, anthropometric and lifestyle variables has been explored. Methods Population-based multicentre cross-sectional study, with multistage stratified and cluster random sampling. Participants were contacted by telephone to carry out a questionnaire for the screening of SLE. Investigating rheumatologists evaluated positive results (review of medical records and/or telephone interview, with medical visit if needed) to confirm the diagnosis. To calculate the prevalence and its 95% CI, the sample design was taken into account and weighing was calculated considering age, sex and geographic origin. Multivariate logistic regression models were defined to analyse which sociodemographic, anthropometric and lifestyle variables included in the telephone questionnaire were associated with the presence of SLE. Results 4916 subjects aged 20 years or over were included. 16.52% (812/4916) had a positive screening result for SLE. 12 cases of SLE were detected. The estimated prevalence was 0.21% (95% CI: 0.11, 0.40). SLE was more prevalent in the rural municipalities, with an odds ratio (OR) = 4.041 (95% CI: 1.216, 13.424). Conclusion The estimated prevalence of SLE in Spain is higher than that described in most international epidemiological studies, but lower than that observed in ethnic minorities in the United States or the United Kingdom.


2017 ◽  
Vol 6 (4) ◽  
pp. 7-13 ◽  
Author(s):  
V K Khanal ◽  
R Upreti ◽  
U Oli ◽  
A K Sunny ◽  
A Ghimire ◽  
...  

Injury is a serious public health threat as it is one of the leading cause of death globally. This study aims to assess the prevalence of injury, pattern of injury and its associated factors among people residing in a rural area of Aurabani VDC of Eastern Nepal. A population based cross sectional study was carried out among 552 people residing in selected wards with door to door visit. The prevalence of minor injury was 3.1% and major was 0.4% per year in the study.Most common mode of injury was fall and most common type was incised wound. Injuries mostly occurred in extremities, in morning time, autumn season and in roads while most of the injuries were accidental in nature. 


Author(s):  
Kaushik Tripura ◽  
Kaushik Nag ◽  
Nabarun Karmakar ◽  
Anjan Datta ◽  
Partha Bhattacharjee

Background: Diabetes mellitus, a major lifestyle disease is undoubtedly the most challenging public health problem of 21st century with a worldwide prevalence of 387 million (8.3%).  The objective of this study was to get an estimate of the prevalence of diabetes mellitus and associated factors in a sample of adult population in a peri-urban area of West Tripura.Methods: In a cross-sectional study, prevalence of diabetes mellitus was found among adult population of a peri-urban area (Dukli) of west Tripura from April 2016 to May 2016. Multistage random sampling was followed to include 76 participants. Taking house as a sampling unit, every 5th house was chosen for this study. From every selected house, one adult participant was chosen by simple random sampling until desired sample size was attained. Collected data was compiled and analyzed with the help of statistical package for social sciences (SPSS 16.0.). Chi-square, Fischer exact test was applied to find out association.Results: The mean age of the study participants was 42.21±17.65 years, comprised of 23.7% male and 76.3% female. The prevalence of diabetes mellitus was 17.1% among study participants. Diabetes was found highest in 39-58-year age group (37.5%). Males were more affected with diabetes mellitus (22.2%) compared to females (15.5%). The study also revealed a significant association of diabetes mellitus with family history of diabetes mellitus (p value 0.00).Conclusions: Present study showed very high prevalence of diabetes mellitus among adult population. Healthy lifestyle measures might reduce burden of diabetes mellitus which could be evaluated in future research.


e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Indo Mamesah ◽  
Josefien S. M. Saerang ◽  
Laya M. Rares

Abstract: Visual impairment is defined as a functional limitation of the eye/eyes or visual system and can manifest in decreased visual acuity or contrast sensitivity, visual field loss, photophobia, visual distortion, visual perceptual difficulties, or a combination of them. Examination of the eye and vision assessment are very important to detect conditions that can cause blindness and serious systemic conditions, which cause problems in school performance, or at a more severe level, life threatening. This study aimed to obtain the occurence of refractive anomalies among junior high school students in rural areas. This was an analytical observational study with a cross-sectional design. The study was conducted in SMP I Wori (rural area) and SMP I Airmadidi (urban area). There were 60 respondents; 30 respondents of each school. Distributions of respondent genders were nearly the same for both schools; the number of females was higher than males. The majority of SMP I Airmadidi students were 11 years old (36.7%), meanwhile the majority of SMP Wori students were 13 years (50%). Most student complaints in SMP I Airmadidi were itchy eyes and drowsiness (16.7%), meanwhile in SMP I Wori was headache (18.4%). Visual impairment was found in 16.6% of students of SMP I Airmadidi, meanwhile in SMP I there was no student with refractive anomaly. Conclusion: There was no refractive anomaly found among students of rural area, however, among students of urban area myopia was the refractive anomaly found.Keywords: refractive anomalyAbstrak: Gangguan penglihatan didefinisikan sebagai suatu keterbatasan fungsional pada mata atau kedua mata atau sistem visual yang dapat bermanifestasi terhadap penurunan ketajaman penglihatan atau sensitifitas kontras, hilangnya lapangan penglihatan, photofobia, distorsi visual, kesulitan perseptual visual atau kombinasi dari semua diatas. Pemeriksaan mata dan penilaian penglihatan sangat penting untuk mendeteksi kondisi yang dapat menyebabkan kebutaan dan kondisi sistemik serius, yang memicu masalah performa di sekolah, atau pada tingkat yang lebih berat, mengancam kehidupan anak. Penelitian ini bertujuan untuk mengetahui gambaran kelainan refraksi pada anak SMP di daerah pedesaan. Jenis penelitian ini analitik observasional dengan desain potong lintang. Penelitian dilakukan di SMPN I Wori (daerah luar Minahasa Utara/pedesaan) dan SMPN I Airmadidi (kota Kabupaten Minahasa Utara), dan diperoleh 60 responden penelitian. Distribusi jenis kelamin responden kedua sekolah hampir sama dimana jumlah perempuan lebih banyak dari laki-laki. Usia terbanyak di SMPN I Airmadidi ialah 11 tahun (36,7%) sedangkan di SMPN Wori 13 tahun (50%). Keluhan terbanyak siswa di SMPN I Airmadidi ialah mata gatal dan rasa kantuk (16,7%), sedangkan di SMPN I Wori ialah sakit kepala (18, 4%). Gangguan penglihatan ditemukan pada responden di SMPN I Airmadidi sebanyak 16,6 % sedangkan di SMPN I tidak ditemukan kelainan visus. Simpulan: Tidak ditemukan adanya gangguan refraksi pada siswa SMP di daerah pedesaan. Kelainan refraksi miopia ditemukan pada siswa SMP di perkotaan.Kata kunci: gangguan refraksi


2021 ◽  
Vol 8 ◽  
Author(s):  
Fatemeh Dehghani Firouzabadi ◽  
Ahmad Jayedi ◽  
Elaheh Asgari ◽  
Zahra Akbarzadeh ◽  
Nasim Janbozorgi ◽  
...  

Objective: We aimed to evaluate the association between the dietary and lifestyle inflammation score (DLIS) and metabolic syndrome (MetS) and its components in a sample of Iranian adults.Design: Population-based cross-sectional study.Setting: General adult population living in Tehran, Iran.Subjects: We included 827 adult men and women with an age range of 18–59 years who were referred to health centers in different districts of Tehran, Iran. Dietary intake was assessed by a semiquantitative food frequency questionnaire with 168 items. The DLIS was calculated based on four components, including dietary inflammation score, physical activity, cigarette smoking, and general obesity. Higher DLIS represents a more proinflammatory diet and lifestyle. The odds ratio (OR) and 95% confidence interval (CI) of the MetS across quartiles of the DLIS was calculated by using logistic regression analysis, controlling for age, sex, energy intake, marital status, education status, and occupation.Results: A total of 827 participants (31% men) were included, with a mean age of 44.7 ± 10.7 years. The prevalence of the MetS was 30.5%. The DLIS ranged between −2.35 and +3.19 (mean ± SD: 0.54 ± 1.09). There was a significant positive association between the DLIS and odds of MetS (OR fourthvs.thefirstquartile: 1.57, 95% CI: 1.01–2.45) in the fully adjusted model.Conclusion: Our results showed a significant positive association between the DLIS and odds of MetS. The results of the present crosssectional study suggested that having a more proinflammatory lifestyle can be associated with MetS. More prospective studies are needed to confirm the findings.


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