Influence of maternal excess weight before pregnancy on breastfeeding and weaning: pooled analyses of four population-based cohorts born between 1982-2015

2021 ◽  
pp. 1-20
Author(s):  
Thaynã Ramos Flores ◽  
Gregore I Mielke ◽  
Alicia Matijasevich ◽  
Iná S Santos ◽  
Mariângela Freitas da Silveira ◽  
...  

Abstract Purpose: To investigate the associations of maternal excess weight before pregnancy with (1) weaning at age 3mo, (2) duration of exclusive breastfeeding at age 6mo, (3) duration of any breastfeeding at age 12mo; and (4) to compare the magnitude of these associations over four decades. Methods: Data were from participants in the Pelotas (Brazil) Birth Cohorts born in 1982 (N=5,334), 1993 (N=1,442), 2004 (N=4,092) and 2015 (N=4,102). Maternal pre-pregnancy weight was collected after the delivery and breastfeeding status was assessed when children were three and 12 months old. Results: Only in the most recent cohort (2015), women with excess weight [body mass index (BMI) ≥ 25 kg/m2) before pregnancy had higher risk of discontinuing exclusive breastfeeding within the first six months post-partum than women with normal weight [HR= 1.22 (95%CI 1.15; 1.30)]. Duration of any type of breastfeeding until 12 months of age was not affected by pre-pregnancy weight. Conclusion: Excess weight before pregnancy is associated with exclusive breastfeeding only in the most recent birth cohort coinciding with increases in weight excess and breastfeeding over time.

SLEEP ◽  
2019 ◽  
Vol 43 (3) ◽  
Author(s):  
I Jaussent ◽  
C M Morin ◽  
H Ivers ◽  
Y Dauvilliers

Abstract Study Objectives To document the rates of persistent, remitted, and intermittent excessive daytime sleepiness (EDS) in a longitudinal 5-year community study of adults and to assess how changes in risk factors over time can predict improvement of daytime sleepiness (DS). Methods Participants were recruited in 2007–2008 as part of a population-based epidemiological study implemented in Canada. They completed postal assessments at baseline and at each yearly follow-up. An Epworth Sleepiness Scale total score >10 indicated clinically significant EDS; a 4-point reduction between two consecutive evaluations defined DS improvement. Socio-demographic, lifestyle, health characteristics, and sleep-related measures (e.g. insomnia symptoms, sleep duration, sleep medication) were self-reported at each time point. Cox proportional-hazard models were used to predict EDS and DS remissions over 5 years. Results Among the 2167 participants, 33% (n = 714) met criteria for EDS at baseline, of whom 33% had persistent EDS, 44% intermittent EDS, and 23% remitted EDS over the follow-up. Furthermore, 61.4% of 2167 initial participants had stable DS, 27.1% sustained DS improvement and 8.5% transient improvement over the follow-up. The main predictors of EDS remission or DS improvement were normal weight, taking less hypnotics, having hypertension, increased nighttime sleep duration, and decreased insomnia, and depressive symptoms. Conclusions EDS waxes and wanes over time with frequent periods of remission and is influenced by behavioral characteristics and changes in psychological, metabolic, and nighttime sleep patterns. Targeting these predictors in future interventions is crucial to reduce DS in the general adult population.


2019 ◽  
Vol 48 (Supplement_1) ◽  
pp. i16-i25 ◽  
Author(s):  
Alicia Matijasevich ◽  
Cesar G Victora ◽  
Mariangela F Silveira ◽  
Fernando C Wehrmeister ◽  
Bernardo L Horta ◽  
...  

Abstract Background Brazil experienced important progress in maternal and child health in recent decades. We aimed at describing secular trends as well as socioeconomic and ethnic inequalities in reproductive history indicators (birth spacing, previous adverse perinatal outcome, parity and multiple births) over a 33-year span. Methods Four population-based birth cohort studies included all hospital births in 1982, 1993, 2004 and 2015 in Pelotas, Southern Brazil. Information on reproductive history was collected through interviews. Indicators were stratified by family income quintiles and skin colour. Absolute and relative measures of inequality were calculated. Results From 1982 to 2015, the proportion of primiparae increased from 39.2% to 49.6%, and median birth interval increased by 23.2 months. Poor women were more likely to report short intervals and higher parity, although reductions were observed in all income and ethnic groups. History of previous low birthweight was inversely related to income and increased by 7.7% points (pp) over time—more rapidly in the richest (12.1 pp) than in the poorest quintile (0.4 pp). Multiple births increased from 1.7% to 2.7%, with the highest increase observed among the richest quintile and for white women (220% and 70% increase, respectively). Absolute and relative income and ethnic-related inequalities for short birth intervals increased, whereas inequalities for previous low birthweight decreased over time. Conclusions In this 33-year period there were increases in birth intervals, multiple births and reports of previous low-birthweight infants. These trends may be explained by increased family planning coverage, assisted reproduction and a rise in preterm births, respectively. Our results show that socioeconomic and ethnic inequalities in health are dynamic and vary over time, within the same location.


Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1518
Author(s):  
Erika Cortés-Macías ◽  
Marta Selma-Royo ◽  
Cecilia Martínez-Costa ◽  
Maria Carmen Collado

Breastfeeding is critical for adequate neonatal microbial and immune system development affecting neonate health outcomes in the short and long term. There is a great interest in ascertaining which are the maternal factors contributing to the milk microbiota and the potential relevance for the developing infant. Thus, our study aimed to characterize the effect of mixed and exclusive breastfeeding practices on the milk microbiota and to determine the impact of pre-pregnancy body mass index (BMI) and weight gain over pregnancy on its composition. Breast milk samples from 136 healthy women were collected within the first month post-partum and milk microbiota profiling was analyzed by 16S rRNA gene sequencing. Information on breastfeeding habits and maternal-infant clinical data were recorded. Breastfeeding practices (exclusive vs. mixed), maternal pre-gestational BMI, and weight gain over pregnancy contributed to the milk microbiota variation. Pre-gestational normal-weight women with exclusive breastfeeding habits harbored a significantly higher abundance of Bifidobacterium genus, and also, higher alpha-diversity compared to the rest of the women. Our results confirm the importance of controlling weight during pregnancy and breastfeeding practices in terms of milk microbiota. Further studies to clarify the potential impact of these maternal factors on milk and infant development and health will be necessary.


2011 ◽  
Vol 27 (suppl 3) ◽  
pp. s435-s443 ◽  
Author(s):  
Antônio Ignácio de Loyola Filho ◽  
Josélia O. A. Firmo ◽  
Elizabeth Uchôa ◽  
Maria Fernanda Lima-Costa

This study examined differences in the use of medications in two birth cohorts (born from 1916 to 1926 and from 1927 to 1937) among older elderly in the population-based cohort study in Bambuí, Minas Gerais State, Brazil. The study used data on participants who were 71-81 years of age in the baseline survey in 1997 (n = 492) and in the 11th wave, in 2008 (n = 620). The number of medications currently consumed (mean = 4.6 and 3.4, respectively) and prevalence of polypharmacy (46.6% and 29.1%, respectively) were higher in the more recent cohort as compared to the earlier one. These differences were independent of gender, age, schooling, number of medical visits in the previous 12 months, and number of chronic conditions. The more recent cohort showed significant differences in the use of psychoactive drugs, lipid modifying agents, drugs for diabetes, and antithrombotic agents, as well as changes in drugs used for arterial hypertension. In general, these changes are consistent with those observed in elderly populations in high-income countries.


2018 ◽  
Vol 24 (6) ◽  
pp. 446-449
Author(s):  
Taciane Gomes do Prado ◽  
Julio Cesar da Costa ◽  
Maria Raquel de Oliveira Bueno ◽  
Mariana Biagi Batista ◽  
Marcelo Romanzini ◽  
...  

ABSTRACT Introduction: In view of the growing prevalence of childhood excess weight and obesity In Brazil In recent decades, it is necessary to observe how this phenomenon occurs in the period of transition to adolescence. Objective: To verify the tracking of excess weight between childhood and adolescence in schoolchildren of both sexes. Methods: The study has a longitudinal design and the data used are part of a prospective study carried out from 2002 to 2005. Participants included 397 schoolchildren of both sexes (211 boys and 186 girls). The nutritional status was determined by the body mass index, and the participants were divided into the following groups: Normal Weight to Normal Weight, Normal Weight to Excess Weight, Excess Weight to Excess Weight, Excess Weight to Normal Weight. The tracking was analyzed using the intraclass correlation coefficient (ICC) and Kappa (k) index. Results: A significant difference (P <0.05) was observed between all variables (age and anthropometric indicators) between 2002 and 2005 for boys and girls. The ICC indicated tracking classified as high (ICC = 0.87) for the BMI values, and the tracking percentage showed that 87% of the subjects remained in the same category of normal weight and excess weight. The values of k = 0.68 show good tracking (P <0.001), indicating a strong maintenance of the subjects in the normal and excess weight categories. Conclusion: The tracking percentage was high, indicating that both boys and girls maintained the classification of excess weight during the period analyzed. Level of Evidence II; Lesser quality prospective study (eg, patients enrolled at different points in their disease or <80% followup).


2019 ◽  
Vol 48 (Supplement_1) ◽  
pp. i72-i79 ◽  
Author(s):  
Iná S Santos ◽  
Fernando C Barros ◽  
Bernardo L Horta ◽  
Ana M B Menezes ◽  
Diego Bassani ◽  
...  

Abstract Background Brazil has made substantial improvements in the duration of breastfeeding. We use data from four population-based cohorts to examine how trends and inequalities in breastfeeding indicators changed over time in a Brazilian city. Methods Data from four birth cohorts, each including all births in a calendar year (1982, 1993, 2004 and 2015) in the city of Pelotas were used. Information on breastfeeding was collected when children were aged between 3 and 20 months. The prevalences of continued breastfeeding at 1 year of age and of exclusive breastfeeding at 3 months were calculated according to family income, maternal skin colour and sex. Results Prevalence of breastfeeding at 12 months increased from 16% to 41% in the 33-year period. The prevalence of exclusive breastfeeding at 3 months increased from 7% in 1993 to 45% in 2015. Increases in exclusive breastfeeding at 3 months were seen in all socioeconomic groups, but the 2015 rates remain highest (57.2%) among the women in the richest quintile, and lowest among those in the poorest quintile (34.6%). Black mothers were more likely to breastfeed at 12 months than Whites in the four cohorts. In the earlier cohorts, breastfeeding at 12 months was more common among the poor, but by 2015 these differences had disappeared. Conclusions There were important positive changes in breastfeeding practices during this period, but less than half of the children in 2015 were receiving the full benefits of breast milk. Improved breastfeeding practices are being adopted by high-income women to a greater extent than by poor women.


2021 ◽  
pp. flgastro-2020-101745
Author(s):  
Rebecca K Grant ◽  
William M Brindle ◽  
Andrew J Robertson ◽  
Alexander R Robertson ◽  
Gareth-Rhys Jones ◽  
...  

ObjectiveIncreases in incidence of collagenous colitis (CC) have been documented across Europe; however, previous data from NHS Lothian (1998–2003) demonstrated this to be a low-prevalence area. We aimed to assess incidence of CC in NHS Lothian over time by comparing a more recent cohort (2013–2018) with our existing cohort.MethodsAll histologically confirmed diagnoses of CC between 2013 and 2018 were obtained from the NHS Lothian colorectal pathology department (Western General Hospital, Edinburgh). Case record review was performed to obtain relevant demographic and clinical data. Data were also collected regarding the availability of colonoscopy in NHS Lothian.Results224 cases of CC were diagnosed between 2013 and 2018, compared with 25 between 1998 and 2003. Mean annual incidence rose from 0.5/100 000 population to 4.3/100 000 population. Incidence in females ≥60 years old rose from 2.3/100 000 population to 22.4/100 000 population (p<0.001). The total number of colonoscopies performed increased by 179.1% from 15 262 (1998–2003) to 42 600 (2013–2018), with the number of CC cases per 1000 colonoscopies performed rising from 1.7 to 5.3 (p<0.001).ConclusionWe describe the increasing incidence of CC in Southeast Scotland, with temporal trends comparable to other European countries. The increase is particularly marked in older females and parallels increasing numbers of colonoscopies being performed.


2018 ◽  
Vol 35 (2) ◽  
pp. 292-300 ◽  
Author(s):  
Misty A. W. Hawkins ◽  
Janna Colaizzi ◽  
Sarah Rhoades-Kerswill ◽  
Emily D. Fry ◽  
Natalie G. Keirns ◽  
...  

Background: Exclusive breastfeeding for 6 months is recommended; however, women with obesity have lower exclusive breastfeeding rates than their normal weight peers. The impact of the timing of maternal excess adiposity onset is unknown. Research aim: We examined whether the timing of onset of excess weight was related to exclusive breastfeeding duration. Methods: Snowball sampling was used for the cross-sectional Breastfeeding Opinions, Outcomes, Behaviors, and Services online survey. The sample was 1,570 mothers who reported their breastfeeding and weight history. Exclusive breastfeeding duration (for first biological child only) was calculated in months and dichotomously (0=< 6 months exclusive breastfeeding; 1=⩾ 6 months exclusive breastfeeding). Participants self-reported their excess weight onset (0=before/during puberty or 1=after puberty). Results: Analysis of covariance results indicated that earlier onset of excess weight was associated with shorter exclusive breastfeeding ( F (1, 1518) = 11.29, p<.001, η2=.01). Those with excess adiposity onset before or during puberty were 1.6 times more likely to experience exclusive breastfeeding failure (< 6 months exclusive breastfeeding) than those with onset after puberty ( OR = 1.57, β = .46, Wald = 11.81, p = .001). Conclusion: Earlier onset of excess adiposity had an adverse influence on exclusive breastfeeding duration. Women with a history of excess adiposity before or during puberty who want to breastfeed may require additional intervention to promote their breastfeeding success.


2017 ◽  
Vol 68 (7) ◽  
pp. 1438-1441 ◽  
Author(s):  
Sorin Berbece ◽  
Dan Iliescu ◽  
Valeriu Ardeleanu ◽  
Alexandru Nicolau ◽  
Radu Cristian Jecan

Obesity represents a global health problem. According to the latest studies released by the World Health Organisation (WHO), 1.7 billion currently in excess of normal weight individuals, of which approx. 75% are overweight (body mass index - BMI 25 to 30). The common form of excess adipose tissue manifestation in overweight individuals is localized fat deposits with high (abdominal) or low (buttocks and thighs) disposition. Although the overweight can be corrected relatively easy by changing behavioral habits or food, a constant physical exercises program or following a diet food are not accessible to all through the efforts of will, financial and time involved. Several methods have been studied and tested over time to eliminate more or less invasive fat deposits with varying efficacy and adverse effects. Chemical lipolysis using phosphatidylcholine as the basic substance was initially used in hypercholesterolemia and its complications and was rapidly adopted in mesotherapy techniques for the treatment of fat deposits. This study reveals the results obtained using Dermastabilon on a sample of 16 patients, the time allocated to treatment and discomfort being minimal, and rapid and notable results. There were no side effects.


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