Effect of Beconase nasal spray on olfactory function in post-nasal polypectomy patients: a prospective controlled trial

1995 ◽  
Vol 109 (10) ◽  
pp. 941-944 ◽  
Author(s):  
Mohammed El Naggar ◽  
Savita Kale ◽  
Chris Aldren ◽  
Frank Martin

AbstractNumerous studies have postulated the possible benefit of corticosteroids on olfaction in patients with nasal/sinus disease. Twenty-nine patients with bilateral nasal polyps were included in our study using strict selection criteria to reduce other aetiologies of olfactory dysfunction. The University of Pennsylvania Smell Identification Test (UPSIT) was performed pre-operatively on the right and left nostrils separately. Following intranasal polypectomy the patients received a six-week course of beclomethasone nasal spray (Beconase) to one nostril only, with the other acting as a control. The UPSIT scores were again obtained for each nostril separately. Wilcoxon Signed Rank test revealed no statistically significant difference in UPSIT scores between treated and untreated nostrils (p = 0.31; power 70 per cent; ES = 0.47). We conclude that topical beclomethasone does not improve olfaction following nasal polypectomy.

2015 ◽  
Vol 06 (04) ◽  
pp. 511-514 ◽  
Author(s):  
Ayhan Kanat ◽  
Ugur Yazar ◽  
Bulent Ozdemir ◽  
Zerrin O. Coskun ◽  
Ozlem Erdivanli

ABSTRACT Background and Aims: There is no study in the literature that investigates an asymmetric morphological feature of the frontal sinus (FS). Materials and Methods: Four hundred and sixty-nine consecutive direct X-rays of FSs were analyzed for the asymmetry between the right and left sides. When an asymmetry in the height and contour of the FS existed, this difference was quantified. Results: Of the 469 patients, X-rays of 402 patients (85.7%), there was an asymmetry between right and left sides of the FS. Of these 235 (50.1%) were dominant on the left side, whereas 167 (35.6%) were dominant on the right, the sinuses of remaining 67 patients (14.3%) was symmetric. Statistical Analysis: The comparisons between parameters were performed using Wilkinson signed rank test. The relationship between handedness and sinus asymmetry was also examined by two proportions test. There is statistically significant difference between the dominance of left and right FS. Conclusions: Hemispheric dominance may have some effect (s) of on sinus asymmetry of the human cranium. Surgeons sometimes enter the cranium through the FS and knowledge of asymmetric FS is important to minimize surgical complications.


2018 ◽  
Vol 35 (4) ◽  
pp. 706-712 ◽  
Author(s):  
Anjana Srinivasan ◽  
Alex Al Khoury ◽  
Svetlana Puzhko ◽  
Carole Dobrich ◽  
Meira Stern ◽  
...  

Background: Infant tongue-tie can cause breastfeeding problems, which may be improved by frenotomy. However, controversy exists among the medical community. Research aim: To examine the influence of frenotomy on infants with posterior ankyloglossia, by quantifying the changes in breastfeeding and maternal nipple pain using standardized tools. Methods: Newborns ( N = 30) below 12 weeks of age were recruited from the Herzl–Goldfarb Breastfeeding Clinic between April 2014 and April 2015. Diagnosis of posterior ankyloglossia was made clinically. Frenotomy was performed. Mothers received breastfeeding counseling before and after the procedure. Pain and breastfeeding were assessed before the procedure, immediately after the procedure, and after 2 days, 7 days and 14 days. Breastfeeding was assessed using the LATCH Tool and by subjective questioning. Maternal nipple pain was assessed using the Numeric Rating System. Results: No complications were reported with frenotomy. There was a significant improvement in LATCH score immediately post-frenotomy, with an increase in median scores from 7.5 to 8.5 ( p < .0001, Wilcoxon signed rank test). There was a significant decrease in median pain score immediately post-frenotomy, from 3.0 on the left nipple and 3.25 on the right nipple, to 0 bilaterally ( p < .0001, Wilcoxon signed rank test). Subjective improvement in breastfeeding was reported by 90% of mothers immediately after frenotomy and 83% of mothers at Day 14. Conclusion: Frenotomy for posterior ankyloglossia may improve breastfeeding and nipple pain.


2018 ◽  
Vol 12 (1) ◽  
pp. 89 ◽  
Author(s):  
Giyati Retnowati ◽  
Rose Mini Agoes Salim ◽  
Airin Y Saleh

This research aimed to determine the effectiveness of picture in storybook reading to increase kindness in children. This research involved 31 children aged 5-6 years; they were taken from the kindergarten in Bandung as the participants. The intervention was done by reading eight picture books in eight days. The kindness was measured using a measurement instrument created by the researcher, in the form of nine coloured cards that described the behaviour of kindness. The measurement was also done by seeing through the kindness tree and observation sheets that filled out by the teacher. The data analysis using the Wilcoxon Signed-rank test shows a significant difference in the average score of kindness (p<0,05) before and after picture storybook reading. Two weeks after the intervention, the improvement on all kindness behaviours with the post-test score is greater than pre-test score that still can be found. Observation through kindness tree and observational sheets shows the same result.


2019 ◽  
Vol 1 (1) ◽  
pp. 27-40
Author(s):  
Hotman Fredy ◽  
Yetty Murni ◽  
Muhidin

The purpose of this research is to determine whether there are significant differences in the CAR, NPL, ROA, ROE, NIM, BOPO, and LDR between government bank compared to private banks in Indonesia Stock Exchange (IDX) the periode of 2011-2015. Method of sample selection was done by purposive sampling, the samples obtained from government banks such as BNI, BRI, BTN, and Mandiri bank, while from private banks such as BCA, CIMB Niaga, Danamon, and Permata bank. Data analysis methods is hypothesis testing using two different test mean (paired sample t-test) and wilcoxon signed rank test. The results showed that the financial performance of the ratio for CAR, NPL, ROA, NIM, BOPO, and LDR there is no significant difference between the government banks and private bank. While the financial performance of the ROE ratio there are significant differences between the government banks and private banks


Sari Pediatri ◽  
2017 ◽  
Vol 19 (1) ◽  
pp. 14
Author(s):  
Devi Andarwati Roboth ◽  
Djatnika Setiabudi ◽  
Meita Dhamayanti

Latar belakang. Insidens kehamilan remaja terus meningkat. Reduksi risiko komprehensif terbukti efektif meningkatkan pengetahuan, sikap, dan perilaku mencegah kehamilan remaja. Beberapa penelitian membuktikan edukasi abstinensia efektif mencegah kehamilan remaja, namun sebagian lagi tidak.Tujuan. Membandingkan dan menganalisis efektivitas reduksi risiko komprehensif dan edukasi abstinensia dalam meningkatkan pengetahuan, sikap, dan perilaku mencegah kehamilan remaja.Metode. Randomized controlled trial dilakukan sejak Maret sampai April 2017 pada 179 remaja usia 13−18 tahun, di dua sekolah menengah Kabupaten Bandung yang diberikan intervensi reduksi risiko komprehensif dan edukasi abstinensia. Kkuesioner pre dan post test digunakan untuk mengukur efektivitas kedua intervensi. Wilcoxon signed rank test digunakan untuk melihat efektivitas intervensi pada masing-masing kelompok. Mann-Withney U digunakan untuk membandingkan efektivitas kedua intervensi.Hasil. Intevensi reduksi risiko komprehensif bermakna lebih efektif meningkatkan komponen pengetahuan nilai KAP sebesar 19,03% (p<0,001), komponen sikap 8,11% (p<0,001), komponen perilaku 33,33% (p=0,012), serta12,50% (p<0,001) nilai KAP keseluruhan. Edukasi abstinensia meningkatkan komponen pengetahuan 4,55%, sikap 0,00%, perilaku 16,67%, serta nilai KAP keseluruhan 3,077%.Kesimpulan. Intervensi reduksi risiko komprehensif lebih efektif meningkatkan pengetahuan, sikap, dan keterampilan mencegah kehamilan remaja dibandingkan intervensi edukasi abstinensia.


2021 ◽  
Vol 11 (3) ◽  
pp. 247-258
Author(s):  
Revi Candra ◽  
Elmiliyani Wahyuni-S ◽  
Nailatul Hanifah

TThis study aims to determine whether there is a difference in the value of the shares of PT. Kimia Farma Tbk. after the acquisition of PT. Phapros Tbk. The data used is the value of shares consisting of book value, market value, and the intrinsic value of shares of PT. Kimia Farma Tbk, which was taken ten months before the acquisition of PT. Phapros Tbk. by PT Kimia Farma Tbk. This study is a comparative study with a quantitative descriptive approach, data analysis using the Wilcoxon signed-rank test. The results of this study indicate that the book value of PT. Kimia Farma Tbk. which has a significant difference before and after the acquisition, while the indicators of the stock market value and the intrinsic value of PT. Kimia Farma Tbk. does not have a significant difference before and after the acquisition event. 


2021 ◽  
Vol 3 (3) ◽  
pp. 226
Author(s):  
Khairun Nisa’ Dewi ◽  
Rize Budi Amalia ◽  
Budi Utomo

Abstrak Latar Belakang :Menarke merupakan kondisi fisiologis berupa menstruasi pertama yang dialami perempuan. Kurangnya pengetahuan mengenai menarke berdampak pada ketidaksiapan dalam menghadapi menarke.  Pendidikan kesehatan reproduksi dengan media yang sesuai dapat menjadi upaya meningkatkan pengetahuan tentang menarke. Penelitian ini bertujuan untuk menganalisis perbedaan pengaruh pemberian media buku pop-up dan leaflet terhadap peningkatan pengetahuan tentang menarke pada anak perempuan usia pubertas awal. Metode: Penelitian ini merupakan jenis kuasi experimental dengan pendekatan pretest-post test control group design. Jumlah sampel sebanyak 44 anak perempuan usia pubertas awal yang terbagi kedalam kelompok dengan intervensi media buku pop-up dan kelompok dengan intervensi media leaflet. Pengukuran pengetahuan tentang menarke menggunakan kuesioner pre-test dan post-test. Hasil: Uji Wilcoxon Signed Rank Test data pretest-postest pengetahuan pada kelompok yang diberi media leaflet (p=0,001) dan pretest-postest kelompok yang diberi media leaflet (p=0,001). Uji Mann Whitney U-Test data postest kelompok buku pop-up dan kelompok leaflet (p=0.002) (p < 0,05). Kesimpulan: Buku pop-up merupakan media yang lebih efektif dari leaflet untuk meningkatkan pengetahuan tentang menarke pada anak perempuan usia pubertas awal .Abstract Background: Menarche is physiological condition, the first menstruation that happen to women. Lack of knowledge can lead to unreadiness menstrual behaviour. Menstrual education by using visual media can be useful to increase menarche knowlede. This study aims to compare educational media of pop-up book and leaflet to increasing knowledge about menarche. Methods: The type of research was quasi experiment using pretest-posttest group design. The samples taken from 44 female students of SDN Banjarejo I dan II Bojonegoro. Samples consisting of 22 students as leaflet group  and 22 students as pop-up book group. Method of measuring knowledge using pretest and postest questionnaire. Result: Wilcoxon Signed Rank Test indicate there was significant difference between pretest-posttest leaflet group (p=0,001) and pretest-postest pop-up book group (p=0,001). The result of Mann Whitney U-Test indicate there was significant difference of knowledge (p=0,002) beetween postest leaflet group and postest pop-up book group. Conclusion: The conclusion of this study was the pop-up book was found more effective than leaflet in improving menarche knowledge


Eye ◽  
2021 ◽  
Author(s):  
Obaid Kousha ◽  
Sharma Ganesananthan ◽  
Bayan Shahin ◽  
John Ellis ◽  
Andrew Blaikie

Abstract Objectives We compare the optical quality and design characteristic a new low cost solar powered binocular indirect ophthalmoscope (BIO), Holo, to Keeler BIO. Methods Twenty-four participants each examined 10 simulation eyes using both the Holo and the Keeler BIO with a 30-diopter condensing lens. Number of Lea symbols printed on the retina of simulation eyes seen and time taken to identify them was recorded. Stereoacuity of 12 participants was tested while using the BIOs. Using 7-point Likert scale, participants gave feedback on design characteristic of both BIOs. Results There was no statistical difference in number of Lea symbols correctly identified (15.63/20 for Holo vs. 15/20 for Keeler BIO, p = 0.366, paired t test) or time taken to correctly identify each symbol (Holo 0.39 s faster; 95% confidence interval −2.24 to 3.03 s, p = 0.763) using each device. 12 out of 12 participants achieved stereoacuity of 60 arcsec using the Holo while with the Keeler BIO 11 achieved 60 arcsec and one 90 arcsec. There was no statistically significant difference in the scores for clarity of view, quality of illumination, field of view, binocularity, eye strain and robustness between the two devices. The Holo, scored higher for ease of use (6.5 vs. 6, p = 0.00488, Wilcoxon signed-rank test), comfort of wear (6 vs. 5, p = 0.000337) and portability (7 vs. 6, p = 0.000148). Conclusion The Holo has the potential to be a clinically useful yet affordable diagnostic tool suitable for the first time of equipping eye care workers in low resource settings with a BIO at volume.


2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Kisaburo Yamada ◽  
Kenichi Kimoto ◽  
Hirofumi Kono ◽  
Toshiaki Kubota

Purpose. To report our experiences in patients with age-related macular degeneration (AMD) treated initially with intravitreal ranibizumab and then switched to bevacizumab. Methods. We retrospectively reviewed the records of 7 patients (7 eyes) who were treated with monthly injections of intravitreal ranibizumab and then switched to injections of bevacizumab (every 6 weeks) for six months. The best-corrected visual acuity measurements (BCVA) and optical coherence tomography (OCT) were performed at the baseline examination and then at each visit. The Wilcoxon signed-rank test was used for the statistical analysis. Results. Following three monthly ranibizumab treatments, there was no significant difference in the BCVA, while the foveal retinal thickness (FRT) significantly decreased (). Switching from ranibizumab to bevacizumab resulted in maintenance (57.2%) of the BCVA and a further decrease in the FRT () after 6 months. Conclusions. Switching to intravitreal bevacizumab may be effective in patients who wish to discontinue intravitreal ranibizumab treatment due to the high cost.


2020 ◽  
Vol 12 (1) ◽  
pp. 113-122
Author(s):  
Ni Luh Krishna Ratna Sari ◽  
Hamidah Hamidah ◽  
Adijanti Marheni

Peredaran narkoba tidak hanya terjadi di berbagai tempat umum, namun juga di dalam suatu lembaga pemasyarakatan. Bagi narapidana yang merupakan mantan pecandu narkoba di lembaga pemasyarakatan, hal ini dapat mempengaruhi potensi mengalami kekambuhan yang menjadi semakin tinggi. Salah satu upaya yang dapat dilakukan untuk menurunkan potensi mengalami kekambuhan adalah dengan pemberian terapi kognitif perilaku. Tujuan dari penelitian ini adalah menguji efektivitas terapi kognitif perilaku untuk menurunkan potensi kekambuhan pada narapidana mantan pecandu narkoba di salah satu lembaga pemasyarakatan di Bali. Penelitian ini menggunakan metode kuantitatif ekperimen dengan one group pretest-posttest design. Teknik sampling yang digunakan adalah pusposive sampling. Data dianalisis menggunakan uji beda Wilcoxon signed-rank test. Hasil penelitian menunjukkan nilai negative ranks = 3 dengan nilai Z= -1.604 dan Asymp. Sig. = 0.109 (p>0.05). Hal ini berarti tidak ada perbedaan yang signifikan potensi kekambuhan narapidana mantan pecandu narkoba di lembaga pemasyarakatan sebelum dan setelah diberikan terapi kognitif perilaku. Meskipun begitu, angka negative ranks menunjukkan bahwa seluruh skor posttest lebih rendah dari skor pretest sehingga dapat disimpulkan bahwa terapi kognitif perilaku dapat menurunkan potensi kekambuhan pada narapidana mantan pecandu narkoba di lembaga pemasyarakatan.  Drug trafficking not only occurs in various public places but also in prison. For the former drug addicts prisoners, this can affect the potential of relapse to become even higher. One effort to reduce the potential of relapse is by giving cognitive behavioral therapy. The purpose of this study was to examine the effectiveness of cognitive- behavioral therapy to reduce the potential of relapse in former drug addicts at one of the prisons in Bali. This study uses quantitative methods with one group pretest-posttest design. The sampling technique used is purposive sampling. Data were analyzed using a Wilcoxon signed-rank test. The results showed the value of negative ranks = 3 with Z values = -1.604 and Asymp. Sig. = 0.109 (p> 0.05). It means there is no significant difference in the potential relapse of the former drug addicts prisoners before and after cognitive-behavioral therapy program. However, negative ranks score indicates that all of the posttest scores are lower than the pretest score. So it can be concluded that cognitive-behavioral therapy can reduce the potential of relapse in former drug addicts prisoners.


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