scholarly journals Frontal sinus asymmetry: Is it an effect of cranial asymmetry? X-ray analysis of 469 normal adult human frontal sinus

2015 ◽  
Vol 06 (04) ◽  
pp. 511-514 ◽  
Author(s):  
Ayhan Kanat ◽  
Ugur Yazar ◽  
Bulent Ozdemir ◽  
Zerrin O. Coskun ◽  
Ozlem Erdivanli
Keyword(s):  
Frontal Sinus ◽  
Hemispheric Dominance ◽  
Rank Test ◽  
X Rays ◽  
Signed Rank ◽  
Significant Difference ◽  
Signed Rank Test ◽  
Left And Right ◽  
The Right ◽  
The Relationship

ABSTRACT Background and Aims: There is no study in the literature that investigates an asymmetric morphological feature of the frontal sinus (FS). Materials and Methods: Four hundred and sixty-nine consecutive direct X-rays of FSs were analyzed for the asymmetry between the right and left sides. When an asymmetry in the height and contour of the FS existed, this difference was quantified. Results: Of the 469 patients, X-rays of 402 patients (85.7%), there was an asymmetry between right and left sides of the FS. Of these 235 (50.1%) were dominant on the left side, whereas 167 (35.6%) were dominant on the right, the sinuses of remaining 67 patients (14.3%) was symmetric. Statistical Analysis: The comparisons between parameters were performed using Wilkinson signed rank test. The relationship between handedness and sinus asymmetry was also examined by two proportions test. There is statistically significant difference between the dominance of left and right FS. Conclusions: Hemispheric dominance may have some effect (s) of on sinus asymmetry of the human cranium. Surgeons sometimes enter the cranium through the FS and knowledge of asymmetric FS is important to minimize surgical complications.

Effect of Beconase nasal spray on olfactory function in post-nasal polypectomy patients: a prospective controlled trial

1995 ◽  
Vol 109 (10) ◽  
pp. 941-944 ◽  
Author(s):  
Mohammed El Naggar ◽  
Savita Kale ◽  
Chris Aldren ◽  
Frank Martin
Keyword(s):  
Nasal Spray ◽  
Controlled Trial ◽  
University Of Pennsylvania ◽  
Rank Test ◽  
Nasal Sinus ◽  
Signed Rank ◽  
Significant Difference ◽  
Signed Rank Test ◽  
The Right ◽  
The University

AbstractNumerous studies have postulated the possible benefit of corticosteroids on olfaction in patients with nasal/sinus disease. Twenty-nine patients with bilateral nasal polyps were included in our study using strict selection criteria to reduce other aetiologies of olfactory dysfunction. The University of Pennsylvania Smell Identification Test (UPSIT) was performed pre-operatively on the right and left nostrils separately. Following intranasal polypectomy the patients received a six-week course of beclomethasone nasal spray (Beconase) to one nostril only, with the other acting as a control. The UPSIT scores were again obtained for each nostril separately. Wilcoxon Signed Rank test revealed no statistically significant difference in UPSIT scores between treated and untreated nostrils (p = 0.31; power 70 per cent; ES = 0.47). We conclude that topical beclomethasone does not improve olfaction following nasal polypectomy.

Frenotomy in Infants with Tongue-Tie and Breastfeeding Problems

2018 ◽  
Vol 35 (4) ◽  
pp. 706-712 ◽  
Author(s):  
Anjana Srinivasan ◽  
Alex Al Khoury ◽  
Svetlana Puzhko ◽  
Carole Dobrich ◽  
Meira Stern ◽  
...  
Keyword(s):  
Medical Community ◽  
Rank Test ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Before And After ◽  
Signed Rank Test ◽  
Breastfeeding Counseling ◽  
The Right ◽  
Breastfeeding Problems ◽  
Numeric Rating

Background: Infant tongue-tie can cause breastfeeding problems, which may be improved by frenotomy. However, controversy exists among the medical community. Research aim: To examine the influence of frenotomy on infants with posterior ankyloglossia, by quantifying the changes in breastfeeding and maternal nipple pain using standardized tools. Methods: Newborns ( N = 30) below 12 weeks of age were recruited from the Herzl–Goldfarb Breastfeeding Clinic between April 2014 and April 2015. Diagnosis of posterior ankyloglossia was made clinically. Frenotomy was performed. Mothers received breastfeeding counseling before and after the procedure. Pain and breastfeeding were assessed before the procedure, immediately after the procedure, and after 2 days, 7 days and 14 days. Breastfeeding was assessed using the LATCH Tool and by subjective questioning. Maternal nipple pain was assessed using the Numeric Rating System. Results: No complications were reported with frenotomy. There was a significant improvement in LATCH score immediately post-frenotomy, with an increase in median scores from 7.5 to 8.5 ( p < .0001, Wilcoxon signed rank test). There was a significant decrease in median pain score immediately post-frenotomy, from 3.0 on the left nipple and 3.25 on the right nipple, to 0 bilaterally ( p < .0001, Wilcoxon signed rank test). Subjective improvement in breastfeeding was reported by 90% of mothers immediately after frenotomy and 83% of mothers at Day 14. Conclusion: Frenotomy for posterior ankyloglossia may improve breastfeeding and nipple pain.

scholarly journals Effectiveness of Picture Story Books Reading to Increase Kindness in Children Aged 5-6 Years

2018 ◽  
Vol 12 (1) ◽  
pp. 89 ◽  
Author(s):  
Giyati Retnowati ◽  
Rose Mini Agoes Salim ◽  
Airin Y Saleh
Keyword(s):  
Test Score ◽  
Measurement Instrument ◽  
Rank Test ◽  
Average Score ◽  
Storybook Reading ◽  
Signed Rank ◽  
Significant Difference ◽  
Before And After ◽  
Post Test ◽  
Signed Rank Test

This research aimed to determine the effectiveness of picture in storybook reading to increase kindness in children. This research involved 31 children aged 5-6 years; they were taken from the kindergarten in Bandung as the participants. The intervention was done by reading eight picture books in eight days. The kindness was measured using a measurement instrument created by the researcher, in the form of nine coloured cards that described the behaviour of kindness. The measurement was also done by seeing through the kindness tree and observation sheets that filled out by the teacher. The data analysis using the Wilcoxon Signed-rank test shows a significant difference in the average score of kindness (p<0,05) before and after picture storybook reading. Two weeks after the intervention, the improvement on all kindness behaviours with the post-test score is greater than pre-test score that still can be found. Observation through kindness tree and observational sheets shows the same result.

Differential expression of c-Met between primary and metastatic sites in clear-cell renal cell carcinoma (ccRCC) and its association with PD-L1 expression.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 4573-4573 ◽  
Author(s):  
Aly-Khan A. Lalani ◽  
Laurence Albiges ◽  
Kathryn P. Gray ◽  
Soumitro Pal ◽  
Jean-Christophe Pignon ◽  
...  
Keyword(s):  
Clear Cell ◽  
Rank Test ◽  
Preclinical Models ◽  
Cell Renal Cell Carcinoma ◽  
Primary Tumors ◽  
Signed Rank ◽  
Programmed Death ◽  
Signed Rank Test ◽  
Metastatic Sites ◽  
The Relationship

4573 Background: Preclinical models show that c-Met promotes survival of renal cancer cells through the regulation of programmed death-ligand 1 (PD-L1). The relationship between c-Met and PD-L1 in human ccRCC is not well characterized. We compared c-Met expression between primary and metastatic sites in ccRCC tissues and evaluated the association with PD-L1 expression. Methods: Pairedprimary and metastatic samples from 45 ccRCC patients were included. Areas with predominant and highest Fuhrman nuclear grade (FNG) were selected. c-Met expression was evaluated by IHC using an anti-Met monoclonal antibody (MET4 Ab, VARI) and calculated by a combined score (CS, 0-300) as: intensity of c-Met staining (0-3) x % of positive cells (0-100). PD-L1 expression was previously assessed by IHC (PMID: 26014095). c-Met expression (average c-Met CS) between paired primary and metastatic samples were compared using Wilcoxon signed-rank test. Associations of c-Met expression with PD-L1 expression (+/-) and other clinical features were assessed with Wilcoxon rank-sum tests. Results: Our cohort included 45 primary ccRCCs and 54 corresponding metastases. c-Met expression was higher in metastatic sites compared to primary (c-Met CS: 55 vs. 28, p=0.0003) and was numerically-greater in PD-L1+ vs. PD-L1- tumors. Higher c-Met expression was associated with higher FNG and T-stage in both primary and metastatic sites (Table). Conclusions: Higher c-Met expression in metastases compared to paired primary tumors in our cohort of ccRCC suggests that testing for biomarkers of response to c-Met inhibitors should be conducted in metastases. Although the observation of higher c-Met expression in PD-L1+ tumors requires further investigation, it supports exploring these targets in combination trials. [Table: see text]

Comparison of Pediatric Voice Handicap Index Scores with Perceptual Voice Analysis in Patients following Airway Reconstruction

2009 ◽  
Vol 118 (8) ◽  
pp. 581-586 ◽  
Author(s):  
Alessandro de Alarcon ◽  
Susan Baker Brehm ◽  
Lisa N. Kelchner ◽  
Jareen Meinzen-Derr ◽  
Janet Middendorf ◽  
...  
Keyword(s):  
Voice Quality ◽  
Voice Handicap Index ◽  
Rank Test ◽  
Perceptual Evaluation ◽  
Signed Rank ◽  
Airway Reconstruction ◽  
Signed Rank Test ◽  
Expert Ratings ◽  
Relationship Of ◽  
The Relationship

Objectives We performed a retrospective review to compare a subjective parental proxy-derived voice handicap survey to an observer-derived method of measuring voice perturbation in children who have undergone airway reconstruction. The main outcome measures were the Pediatric Voice Handicap Index (pVHI) total score and the Overall Severity score on the Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V). Methods The percent Overall Severity CAPE-V score (score divided by 100) and the percent pVHI score (score divided by 92) were calculated. A Wilcoxon signed rank test was used to compare CAPE-V scores with the pVHI total scores. The relationship between the pVHI scores and the CAPE-V scores was investigated with a Spearman correlation. Subgroup analysis was performed to determine the relationship of surgery type to CAPE-V and pVHI scores. Results Fifty subjects with a history of airway surgery who were evaluated between 2005 and 2008 were identified. Forty-two of the 50 subjects had complete data for review. Their median age was 7.1 years (range, 3.3 to 17.9 years). Their pVHI total scores had a median of 30 (range, 1 to 80). Their Overall Severity CAPE-V scores had a median of 50.5 (range, 0 to 98). Their median CAPE-V percent was higher than their median pVHI percent (50.5% versus 32.6%; p = 0.0003). A weak correlation was found between the Overall Severity CAPE-V score and the pVHI total score (rho = 0.41; p = 0.0003). There was a trend toward higher Overall Severity CAPE-V scores in patients who underwent cricotracheal resection. The total number of airway surgeries was significantly correlated with the Overall Severity CAPE-V score (rho = 0.6; p < 0.0001) but not with the pVHI score. Conclusions Children who undergo airway reconstruction often have a resulting voice disturbance that can affect their lives in multiple dimensions. The results of this study revealed a weak-to-fair correlation between the parent-reported pVHI total score and expert ratings of voice quality using the CAPE-V. In this patient population, both of these tools provided important information regarding the relationship of the severity of voice disturbance to its handicapping effects.

scholarly journals Analisis Perbandingan Kinerja Keuangan Bank Umum BUMN Dan Bank Umum Swasta Yang Terdaftar Di Bursa Efek Indonesia Tahun 2011 - 2015

2019 ◽  
Vol 1 (1) ◽  
pp. 27-40
Author(s):  
Hotman Fredy ◽  
Yetty Murni ◽  
Muhidin
Keyword(s):  
Financial Performance ◽  
Stock Exchange ◽  
Sample Selection ◽  
Rank Test ◽  
Private Bank ◽  
Signed Rank ◽  
Significant Difference ◽  
Private Banks ◽  
Signed Rank Test ◽  
The Government

The purpose of this research is to determine whether there are significant differences in the CAR, NPL, ROA, ROE, NIM, BOPO, and LDR between government bank compared to private banks in Indonesia Stock Exchange (IDX) the periode of 2011-2015. Method of sample selection was done by purposive sampling, the samples obtained from government banks such as BNI, BRI, BTN, and Mandiri bank, while from private banks such as BCA, CIMB Niaga, Danamon, and Permata bank. Data analysis methods is hypothesis testing using two different test mean (paired sample t-test) and wilcoxon signed rank test. The results showed that the financial performance of the ratio for CAR, NPL, ROA, NIM, BOPO, and LDR there is no significant difference between the government banks and private bank. While the financial performance of the ROE ratio there are significant differences between the government banks and private banks

scholarly journals SHARE VALUE DIFFERENCES PT. KIMIA FARMA TBK TOWARDS THE ACQUISITION OF SHARE EVENTS IN PT. PHAPROS TBK

2021 ◽  
Vol 11 (3) ◽  
pp. 247-258
Author(s):  
Revi Candra ◽  
Elmiliyani Wahyuni-S ◽  
Nailatul Hanifah
Keyword(s):  
Intrinsic Value ◽  
Market Value ◽  
Rank Test ◽  
Book Value ◽  
Value Differences ◽  
Signed Rank ◽  
Significant Difference ◽  
Before And After ◽  
Signed Rank Test ◽  
Quantitative Descriptive

TThis study aims to determine whether there is a difference in the value of the shares of PT. Kimia Farma Tbk. after the acquisition of PT. Phapros Tbk. The data used is the value of shares consisting of book value, market value, and the intrinsic value of shares of PT. Kimia Farma Tbk, which was taken ten months before the acquisition of PT. Phapros Tbk. by PT Kimia Farma Tbk. This study is a comparative study with a quantitative descriptive approach, data analysis using the Wilcoxon signed-rank test. The results of this study indicate that the book value of PT. Kimia Farma Tbk. which has a significant difference before and after the acquisition, while the indicators of the stock market value and the intrinsic value of PT. Kimia Farma Tbk. does not have a significant difference before and after the acquisition event. 

scholarly journals PERBEDAAN PENGARUH MEDIA BUKU POP-UP DAN LEAFLET TERHADAP PENGETAHUAN MENARKE PADA ANAK PEREMPUAN PUBERTAS AWAL

2021 ◽  
Vol 3 (3) ◽  
pp. 226
Author(s):  
Khairun Nisa’ Dewi ◽  
Rize Budi Amalia ◽  
Budi Utomo
Keyword(s):  
Test Data ◽  
Rank Test ◽  
Group Method ◽  
Group Design ◽  
Signed Rank ◽  
Significant Difference ◽  
Wilcoxon Signed Rank Test ◽  
Post Test ◽  
Signed Rank Test ◽  
Book Group

Abstrak Latar Belakang :Menarke merupakan kondisi fisiologis berupa menstruasi pertama yang dialami perempuan. Kurangnya pengetahuan mengenai menarke berdampak pada ketidaksiapan dalam menghadapi menarke.  Pendidikan kesehatan reproduksi dengan media yang sesuai dapat menjadi upaya meningkatkan pengetahuan tentang menarke. Penelitian ini bertujuan untuk menganalisis perbedaan pengaruh pemberian media buku pop-up dan leaflet terhadap peningkatan pengetahuan tentang menarke pada anak perempuan usia pubertas awal. Metode: Penelitian ini merupakan jenis kuasi experimental dengan pendekatan pretest-post test control group design. Jumlah sampel sebanyak 44 anak perempuan usia pubertas awal yang terbagi kedalam kelompok dengan intervensi media buku pop-up dan kelompok dengan intervensi media leaflet. Pengukuran pengetahuan tentang menarke menggunakan kuesioner pre-test dan post-test. Hasil: Uji Wilcoxon Signed Rank Test data pretest-postest pengetahuan pada kelompok yang diberi media leaflet (p=0,001) dan pretest-postest kelompok yang diberi media leaflet (p=0,001). Uji Mann Whitney U-Test data postest kelompok buku pop-up dan kelompok leaflet (p=0.002) (p < 0,05). Kesimpulan: Buku pop-up merupakan media yang lebih efektif dari leaflet untuk meningkatkan pengetahuan tentang menarke pada anak perempuan usia pubertas awal .Abstract Background: Menarche is physiological condition, the first menstruation that happen to women. Lack of knowledge can lead to unreadiness menstrual behaviour. Menstrual education by using visual media can be useful to increase menarche knowlede. This study aims to compare educational media of pop-up book and leaflet to increasing knowledge about menarche. Methods: The type of research was quasi experiment using pretest-posttest group design. The samples taken from 44 female students of SDN Banjarejo I dan II Bojonegoro. Samples consisting of 22 students as leaflet group  and 22 students as pop-up book group. Method of measuring knowledge using pretest and postest questionnaire. Result: Wilcoxon Signed Rank Test indicate there was significant difference between pretest-posttest leaflet group (p=0,001) and pretest-postest pop-up book group (p=0,001). The result of Mann Whitney U-Test indicate there was significant difference of knowledge (p=0,002) beetween postest leaflet group and postest pop-up book group. Conclusion: The conclusion of this study was the pop-up book was found more effective than leaflet in improving menarche knowledge

scholarly journals Comparative evaluation of a new frugal binocular indirect ophthalmoscope

Eye ◽  
2021 ◽  
Author(s):  
Obaid Kousha ◽  
Sharma Ganesananthan ◽  
Bayan Shahin ◽  
John Ellis ◽  
Andrew Blaikie
Keyword(s):  
Low Cost ◽  
Optical Quality ◽  
Ease Of Use ◽  
Rank Test ◽  
Design Characteristic ◽  
Signed Rank ◽  
Significant Difference ◽  
Signed Rank Test ◽  
Solar Powered ◽  
Indirect Ophthalmoscope

Abstract Objectives We compare the optical quality and design characteristic a new low cost solar powered binocular indirect ophthalmoscope (BIO), Holo, to Keeler BIO. Methods Twenty-four participants each examined 10 simulation eyes using both the Holo and the Keeler BIO with a 30-diopter condensing lens. Number of Lea symbols printed on the retina of simulation eyes seen and time taken to identify them was recorded. Stereoacuity of 12 participants was tested while using the BIOs. Using 7-point Likert scale, participants gave feedback on design characteristic of both BIOs. Results There was no statistical difference in number of Lea symbols correctly identified (15.63/20 for Holo vs. 15/20 for Keeler BIO, p = 0.366, paired t test) or time taken to correctly identify each symbol (Holo 0.39 s faster; 95% confidence interval −2.24 to 3.03 s, p = 0.763) using each device. 12 out of 12 participants achieved stereoacuity of 60 arcsec using the Holo while with the Keeler BIO 11 achieved 60 arcsec and one 90 arcsec. There was no statistically significant difference in the scores for clarity of view, quality of illumination, field of view, binocularity, eye strain and robustness between the two devices. The Holo, scored higher for ease of use (6.5 vs. 6, p = 0.00488, Wilcoxon signed-rank test), comfort of wear (6 vs. 5, p = 0.000337) and portability (7 vs. 6, p = 0.000148). Conclusion The Holo has the potential to be a clinically useful yet affordable diagnostic tool suitable for the first time of equipping eye care workers in low resource settings with a BIO at volume.

scholarly journals Switching from Intravitreal Ranibizumab to Bevacizumab for Age-Related Macular Degeneration

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Kisaburo Yamada ◽  
Kenichi Kimoto ◽  
Hirofumi Kono ◽  
Toshiaki Kubota
Keyword(s):  
Macular Degeneration ◽  
Intravitreal Bevacizumab ◽  
Age Related Macular Degeneration ◽  
Rank Test ◽  
Intravitreal Ranibizumab ◽  
Age Related ◽  
Signed Rank ◽  
Significant Difference ◽  
Signed Rank Test ◽  
Ranibizumab Treatment

Purpose. To report our experiences in patients with age-related macular degeneration (AMD) treated initially with intravitreal ranibizumab and then switched to bevacizumab. Methods. We retrospectively reviewed the records of 7 patients (7 eyes) who were treated with monthly injections of intravitreal ranibizumab and then switched to injections of bevacizumab (every 6 weeks) for six months. The best-corrected visual acuity measurements (BCVA) and optical coherence tomography (OCT) were performed at the baseline examination and then at each visit. The Wilcoxon signed-rank test was used for the statistical analysis. Results. Following three monthly ranibizumab treatments, there was no significant difference in the BCVA, while the foveal retinal thickness (FRT) significantly decreased (). Switching from ranibizumab to bevacizumab resulted in maintenance (57.2%) of the BCVA and a further decrease in the FRT () after 6 months. Conclusions. Switching to intravitreal bevacizumab may be effective in patients who wish to discontinue intravitreal ranibizumab treatment due to the high cost.

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