Serum immunoglobulins in patients with chronic tonsillitis

AbstractSerum immunoglobulin (IgG, IgA and IgM) levels were determined in patients with chronic tonsillitis before and one month after tonsillectomy. The preoperative levels of serum IgG, IgA and IgM were significantly higher when compared with the controls. The increase may be due to repeated antigenic stimulation. The post-operative levels for the three immunoglobulins were decreased; however, a significant reduction was observed for IgG only where the mean value was comparable with the control group. The data confirm that tonsillectomy does not disturb the humoral immune system of the body.

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The Effect of Propanolol on C-Reactive Protein in Patients with Severe Burns at Dr Soetomo Hospital Surabaya

Jurnal Rekonstruksi dan Estetik ◽

10.20473/jre.v4i1.24352 ◽

2021 ◽

Vol 4 (1) ◽

pp. 27

Author(s):

Muhammad Aulia U H ◽

Iswinarno Doso Saputro ◽

Magda Rosalina Hutagalung

Keyword(s):

Treatment Group ◽

Albumin Level ◽

Mean Value ◽

The Body ◽

Control Group ◽

Control Group Design ◽

Severe Burns ◽

Hypermetabolic State ◽

Post Test ◽

The Mean

Background: The incidence of burns in Indonesia progressively increases with the increase in its population and industries. From January to September 2000, 158 patients were treated in the burn unit of Dr Soetomo Hospital with a mortality rate reaching 5,8%. Burns have a direct effect in causing both local and systemic changes in the body, not occurring in other injuries. In severe burns, a hypermetabolic state can occur, which increases cardiac workload and causes muscle atrophy and other morbidities. The purpose of this study is to examine the effect of propranolol on the hypermetabolic state in severely burned patients by measuring various clinical & laboratory parameters.Methods : This is an experimental study using pre and post test control group design with the objective of assessing the treatment outcome with oral propranolol given in 15 consecutive days for burn patients involving 25%- 60% TBSA. Measurements were taken three times, on day 0, 7 and 14.Results : Obtained 16 samples divided into 2 groups. In the treatment group, there was a significant decrease in CRP levels on days 0, 7 and 14 (p <0.05). The Mid Arm Circumference variable did not obtain a significant decreasing on days 0, 7 and 14. The albumin level studied showed a significant decreasing on day 0 & 7 days with a value of p = 0.045. From the comparison between the two groups, there were significant differences in CRP levels on days 0 & 14, with the mean value of the treatment group -5.12 + 2.88 and the mean value of the control group 2.86 + 7.37, and the value of p = 0.019.Conclusions: This study successfully proved that the administration of propranolol can overcome the effects of hypermetabolism which is characterized by decreasing in CRP levels.

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HUMORAL IMMUNE RESPONSE OF CHILDREN WITH SHIGELLOSIS AND INFECTED WITH CYTOMEGALOVIRUS

Експериментальна і клінічна медицина ◽

10.35339/ekm.2019.85.04.09 ◽

2019 ◽

Vol 85 (4) ◽

pp. 62-66

Author(s):

S.M. Bukiy

Keyword(s):

Immune Response ◽

Immune System ◽

Comparative Analysis ◽

Young Children ◽

Humoral Immune Response ◽

Control Group ◽

Cmv Infection ◽

Humoral Immune ◽

Humoral Immune System ◽

Diagnostic Criterion

A comparative analysis of the humoral immune response in shigellosis in 90 children aged four to ten years infected with cytomegolovirus (CMV) was performed. It was found that shigellosis in young children on the background of CMV infection is characterized by torpid changes in the parameters of the main classes of immunoglobulins in the dynamics of the disease. with the exception of serum IgG. The IgG content in patients with shigellosis and infected with CMV is significantly higher both in comparison with the control group. and in children without concomitant infection. The revealed features of the response of the humoral immune system can be an auxiliary diagnostic criterion for the infection of CMV in children with shigellosis. as well as the cause of the development of an unfavorable course of the disease. which requires further investigation.

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Generated Immune Responses and Antibody-Mediated Immunity Against Corona Virus Disease-19: An Updated Review

Disease and Diagnosis ◽

10.34172/ddj.2020.07 ◽

2020 ◽

Vol 9 (4) ◽

pp. 163-171

Author(s):

Faezeh Malekzadeh ◽

Shaghayegh Kermaninezhad ◽

Amin Reza Nikpoor ◽

Mohammad Ali Vahidipour ◽

Ali Salimi Asl

Keyword(s):

Immune System ◽

Virus Disease ◽

Chronic Phase ◽

Immunoglobulin M ◽

The Body ◽

Igg Antibodies ◽

Igg Antibody ◽

Humoral Immune ◽

Humoral Immune System

Coronavirus disease 2019 (COVID-19) is a new pathogen which has become an uncontrollable pandemic. On the other hand, the humoral immune system, as a defensive line, protects the body by producing antibodies. Immunoglobulin M (IgM) and G (IgG) are considered as the most important antibodies that are produced by the immune system of the host. Previous evaluations on the production of IgM and IgG antibodies by patients suffering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection specifies that IgM is an acute phase antibody and increases on the first days of infection. Then, as the chronic phase begins, the level of the IgM decreases and switches to the production of IgG. In addition, the durability of the IgG antibody shows the duration of the immunity against COVID-19. Thus, the present review article focused on the antibody production mechanism in studies conducted on COVID-19 patients, the protection role of antibodies, and their stability.

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Effect of High Plane of Nutrition on Blood Biochemical Profile and Onset of Puberty in Prepubertal HF X Kankrej Crossbred Heifers

THE INDIAN JOURNAL OF VETERINARY SCIENCES AND BIOTECHNOLOGY ◽

10.21887/ijvsbt.15.2.4 ◽

2019 ◽

Vol 15 (02) ◽

pp. 14-17

Author(s):

K K Hadiya ◽

A J Dhami ◽

D V Chaudhari ◽

P M Lunagariya

Keyword(s):

Body Weight ◽

Treatment Group ◽

Plasma Levels ◽

Age Of Onset ◽

The Body ◽

Monthly Interval ◽

Control Group ◽

Blood Biochemical ◽

Lower Protein ◽

The Mean

This study was initiated on 24 prepubertal Holstein x Kankrej crossbred heifers of nearly identical age (7-9 months) and body weight (130-140 kg) at University farm to evaluate the effect of high plane of nutrition on blood biochemical and minerals profile and the age at puberty. Twelve heifers were managed under routine farm feeding (control) and the rest 12 under ideal optimum feeding regime (treatment) that included extra 1 kg concentrate, 30 g min mix and ad-lib dry fodder. The body weight and ovarian ultrasonography together with blood sampling was carried out at monthly interval from 10 to 18 months of age to study the ovarian dynamics and blood biochemical changes. High plane of nutrition to growing heifers was beneficial in reducing the age of onset of puberty (by 2-3 months) compared to routine farm fed group. The mean plasma total protein and cholesterol concentrations showed a rising trend with significant variations from 10 to 16 months of age, where it got mostly stabilized indicating adult profile. The activity of enzymes GOT and GPT also rose gradually and significantly from 10 months till 14-15 months of age, and thereafter it remained more or less static till 18 months of age. The levels of both these enzymes were higher, with lower protein and cholesterol, in control than the treatment group from 15-16 months of age onwards. The mean plasma levels of both calcium and phosphorus increased gradually and significantly with advancing age till 16-17 months of age, with little higher values in supplemented than a control group. The plasma levels of zinc, iron, copper, and cobalt also showed rising trend with significant differences between 10th and 12th-14th months of age, and from 15th to 18th months of age the levels were statistically the same in all the groups with slightly higher values in the treatment group.

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Assessment of the Tissue Response to Modification of the Surface of Dental Implants with Carboxyethylphosphonic Acid and Basic Fibroblastic Growth Factor Immobilization (Fgf-2): An Experimental Study on Minipigs

Biology ◽

10.3390/biology10050358 ◽

2021 ◽

Vol 10 (5) ◽

pp. 358

Author(s):

Javier Aragoneses ◽

Ana Suárez ◽

Nansi López-Valverde ◽

Francisco Martínez-Martínez ◽

Juan Manuel Aragoneses

Keyword(s):

Surface Treatment ◽

Test Group ◽

Mean Value ◽

Control Group ◽

P Value ◽

Implant Surface ◽

Bone Contact ◽

Bone Implant ◽

Significant Difference ◽

The Mean

The aim of this study was to evaluate the effect of implant surface treatment with carboxyethylphosphonic acid and fibroblast growth factor 2 on the bone–implant interface during the osseointegration period in vivo using an animal model. The present research was carried out in six minipigs, in whose left tibia implants were inserted as follows: eight implants with a standard surface treatment, for the control group, and eight implants with a surface treatment of carboxyethylphosphonic acid and immobilization of FGF-2, for the test group. At 4 weeks after the insertion of the implants, the animals were sacrificed for the histomorphometric analysis of the samples. The means of the results for the implant–bone contact variable (BIC) were 46.39 ± 17.49% for the test group and 34.00 ± 9.92% for the control group; the difference was not statistically significant. For the corrected implant–bone contact variable (BICc), the mean value of the test group was 60.48 ± 18.11%, and that for the control group, 43.08 ± 10.77%; the difference was statistically significant (p-value = 0.035). The new bone formation (BV/TV) showed average results of 27.28 ± 3.88% for the test group and 26.63 ± 7.90% for the control group, meaning that the differences were not statistically significant (p-value = 0.839). Regarding the bone density at the interthread level (BAI/TA), the mean value of the test group was 32.27 ± 6.70%, and that of the control group was 32.91 ± 7.76%, with a p-value of 0.863, while for the peri-implant density (BAP/TA), the mean value of the test group was 44.96 ± 7.55%, and that for the control group was 44.80 ± 8.68%, without a significant difference between the groups. The current research only found a significant difference for the bone–implant contact at the cortical level; therefore, it could be considered that FGF-2 acts on the mineralization of bone tissue. The application of carboxyethylphosphonic acid on the surface of implants can be considered a promising alternative as a biomimetic coating for the immobilization of FGF-2. Despite no differences in the new bone formation around the implants or in the interthread or peri-implant bone density being detected, the biofunctionalization of the implant surface with FGF-2 accelerates the mineralization of the bone–implant interface at the cortical level, thereby reducing the osseointegration period.

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The humoral immune system of anadromous fish

Developmental & Comparative Immunology ◽

10.1016/j.dci.2016.12.008 ◽

2018 ◽

Vol 80 ◽

pp. 24-33 ◽

Cited By ~ 9

Author(s):

Patty Zwollo

Keyword(s):

Immune System ◽

Anadromous Fish ◽

Humoral Immune ◽

Humoral Immune System

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Effect of Activity-Based Games on Students' Academic Achievement in Social Sciences

FWU Journal of Social Sciences ◽

10.51709/19951272/fall-2021/5 ◽

2021 ◽

pp. 82-95

Keyword(s):

Academic Achievement ◽

Performance Test ◽

Mean Value ◽

Control Group ◽

Second Phase ◽

Initial Stage ◽

Post Test ◽

The Mean ◽

Based Instruction ◽

Experimental Group

The purpose of the research was to investigatethe effect of activity-based games on the academic achievement of graduate-level pupils in social sciences.An experimental research design with a pre-and post-test control group was used in this study. As pre-test and post-test, MCQ achievement tests containing 70 items were used as research methods for data collecting. The initial stage in this initiative was to collect data on what inspires children to learn. Both groups took a pre-test, and the results were tallied.The project's second phase was to study the effects of variousactivities on academic achievement. Both groups were given an MCQ performance test. The T-test was used to analyze the data. The findings of this study demonstrated that, compared to the control group, mostpupils'marks improved in the experimental group. The mean value showedthat experimental group participants scored 18.77on the post-test, while control group students scored 16.21. According to a post-lesson poll, most students regarded activity-based games to be more engaging than lecture-based instruction.

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A STUDY ON THE EFFECTIVENESS OF USING ALPHABET CARDS GAME IN TEACHING VOCABULARY FOR COMMERCIAL BUSINESS ADMINISTRATION STUDENTS

UAD TEFL International Conference ◽

10.12928/utic.v1.150.2017 ◽

2017 ◽

Vol 1 ◽

pp. 54

Author(s):

Arita Destianingsih ◽

Ari Satria

Keyword(s):

Business Administration ◽

Mean Value ◽

T Test ◽

Control Group ◽

Business Administration Students ◽

Post Test ◽

Quasi Experimental ◽

The Mean ◽

Experimental Group ◽

Administration Students

The aim of this study was to know the effectiveness of the use of alphabet cards game as interesting tool to explain vocabularies and it make it easier to remember their meanings. This study belongs to the quasi experimental research and presents pre-test, post test and to investigate the effect of using alphabet cards game on vocabulary mastery of commercial business administration students. The participants were the students from commercial business administration students at the third semester (N=54) of State Polytechnic Bengkalis and divided into two groups. Both groups were taught vocabulary, however, the experimental group students who are exposed to alphabet cards game and the controlled group students who received conventional method. Pre-test and post-test were given to both experimental group students and controlled group students. The score of the vocabulary tests were compared through independent sample t-test. The mean value of pre-test of experimental class was 61.35, while the control class was 52.23. After learning using alphabet card games in experimental class the mean value obtained in post-test was 78.85, while in control class was 59.04. The improved of learning outcomes can be seen from the level of significance was 0.000 and it was lower than t test 0.000<0.05. It means that the hypothesis null is not accepted. Therefore, it can be concluded that the score of the students in learning vocabulary between the experimental group and control group was significantly different. The experimental group students who learned vocabulary using alphabet cards game had increased their vocabulary mastery.

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