scholarly journals The Effect of Propanolol on C-Reactive Protein in Patients with Severe Burns at Dr Soetomo Hospital Surabaya

2021 ◽  
Vol 4 (1) ◽  
pp. 27
Author(s):  
Muhammad Aulia U H ◽  
Iswinarno Doso Saputro ◽  
Magda Rosalina Hutagalung

Background: The incidence of burns in Indonesia progressively increases with the increase in its population and industries. From January to September 2000, 158 patients were treated in the burn unit of Dr Soetomo Hospital with a mortality rate reaching 5,8%. Burns have a direct effect in causing both local and systemic changes in the body, not occurring in other injuries. In severe burns, a hypermetabolic state can occur, which increases cardiac workload and causes muscle atrophy and other morbidities. The purpose of this study is to examine the effect of propranolol on the hypermetabolic state in severely burned patients by measuring various clinical & laboratory parameters.Methods : This is an experimental study using pre and post test control group design with the objective of assessing the treatment outcome with oral propranolol given in 15 consecutive days for burn patients involving 25%- 60% TBSA. Measurements were taken three times, on day 0, 7 and 14.Results : Obtained 16 samples divided into 2 groups. In the treatment group, there was a significant decrease in CRP levels on days 0, 7 and 14 (p <0.05). The Mid Arm Circumference variable did not obtain a significant decreasing on days 0, 7 and 14. The albumin level studied showed a significant decreasing on day 0 & 7 days with a value of p = 0.045. From the comparison between the two groups, there were significant differences in CRP levels on days 0 & 14, with the mean value of the treatment group -5.12 + 2.88 and the mean value of the control group 2.86 + 7.37, and the value of p = 0.019.Conclusions: This study successfully proved that the administration of propranolol can overcome the effects of hypermetabolism which is characterized by decreasing in CRP levels.

Author(s):  
Edy Irawan ◽  
Syarifuddin Dahlan ◽  
Een Y. Haenilah ◽  
Tubagus Ali Rachman Puja Kesuma ◽  
Albet Maydiantoro ◽  
...  

This research is motivated by the problems of students who fail to achieve happiness in their lives; this is caused by the inability of students to make adjustments to all forms of change in maintaining survival. Efforts that can be made to overcome this problem are to provide group guidance services with game techniques. This study aims to test whether the game technique in group guidance services is effective for improving students' self-adjustment. The method used in this research is experimental research using Pretest-Posttest Control Group Design. The results showed that there was a change in the mean value at the pre-test of 93.43 for the experimental class and 92.57 for the control class and the mean value at the post-test of 151.64 for the experimental class and 98.71 for the control class. So that the mean value at the time of post-test increased by 58.21 for the experimental group and 06.14 for the control group. These changes mean that group guidance with game techniques is empirically proven to be effective in increasing student adaptation


2021 ◽  
Vol 21 (no 1) ◽  
Author(s):  
Gede Widhiantara ◽  
Anak Agung Ayu Putri Permatasari ◽  
Putu Angga Wiradana

This study aims to determine the morphology of Leydig cells in hyperlipidemic wistar rats after having administered with sembung (Blumea balsamifera) extract orally. This study utilised a randomized post-test only control group design. The sample in this study were 16 adult male wistar rats (Rattus novergicus) aged 3-4 months with a body weight of 150-200 grams, which were equally and randomly divided into two groups, namely control group (hyperlipidaemia and sterile aquadest) and treatment group (hyperlipidaemia and sembung leaf extract). Hyperlipidaemia was induced with lard administration for 50 days. Data were analysed statistically using the Independent t-test. The results showed that the number of Leydig cells in the treatment group was higher than the control group with 68.13 ± 1.89 and 55.63 ± 1.92 cells respectively (P <0.05). In addition, the mean Leydig cell core diameter of the control group, 5.00 ± 0.34 µm, was smaller compared to the treatment group which was 5.80 ± 0.20 µm (P <0.05). It can be inferred that sembung leaf extract provides a protective effect against damage to Leydig cells due to hyperlipidaemia.


2019 ◽  
Vol 3 (1) ◽  
pp. 1
Author(s):  
Aris Setyawan

Peer-assisted learning (PAL) has been shown to help improve clinical skills. Nevertheless, the PAL method has not been able to provide sufficient training opportunities for participant students due to space and time constraints. The existence of technological developments in the field of education, a new opportunity for lecturers to answer the needs and create innovation using online Peer-assisted learning in supporting the learning process. The purpose of this research was to know difference of clinical skill value of student and learning motivation of student before and after the application of Online peer assisted learning method. The type of this research was quantitative with quasy experimental pre-test and post-test with control group design. The study was conducted in Nursing Study Department of STIKes Surya Global Yogyakarta with a 70 sample from second year students which randomly is devided into control and intervention group. The intervention group was given a peer-assisted learning (PAL) model with the help of video call technology in WhatsApp application. Control group with peer-assisted learning face to face model has ben done usualy. A checklist of clinical skills of thoracic examination and questioner of learning motivation was used as instrument. The result of this research was the mean value of the intervention group learning motivation was 100,6 while the mean value of the learning motivation of the control group was 95,02. The mean value of clinical skills in the pre-test control group of 82,45 and the mean post-test increased to of 87,41. The clinical skill delta value of the intervention group was 5,04 while the control group's delta value was 4,76. The conclusion was the OPAL method has been shown to increase learning motivation and the value of clinical skills of thoracic physical examination in nursing students


2017 ◽  
Vol 13 (2) ◽  
pp. 205
Author(s):  
Sri Tasminatun ◽  
Ria Pravitasari ◽  
SN. Nurul Makiyah

Abstract: The diameter of the alba pulp of the spleen will be enlarged, when the body responds to allergens by increasing the activity of the immune system. Papaya fruits (Carica papaya L.) containing flavonoid that can be as an immunomodulator. This study aims to determine the effect of C. papaya extract to the diameter size alba pulp of the spleen of Ovalbumin (OVA) induced Balb/C mice. The research design was experimental in vivo animal test with post-test only control group design. Thirty male Balb/C mice, ±20grams weight, 8 weeks old, divided into six groups consists of a normal control, negative control, Methylprednisolone, and C. papaya extract treatment group (175mg/kg, 350mg/kg and 700mg/kg dose per day). The extract and Methylprednisolone are given for 28 days, while OVA is given on 15thand 22ndday (intraperitoneal,) and 23rd until 28thday (peroral). On the 29thday the mice are sacrificed and the duodenum was made into histological preparation with HE staining. The immunomodulator effect is assessed by the average of the diameter size alba pulp of the spleen under a light microscope. The data were analyzed using SPSS15 with one way ANOVA continued with Tukey test. The average of the diameter size alba pulp of the spleen for control group is 10,165 ± 0,195; negative control group is 30,357 ± 0,826; methylprednisolone group is 10,220 ± 0,346; 175mg/kgbb dose extract is 14,956 ± 1,057; 350mg/kgbb dose extract is 14,030 ± 0,667; and 700mg/kgbb dose extract is 12,504 ± 0,729. The conclusion of this study is Carica papaya L. extract treatment group (175mg/kg, 350mg/kg and 700mg/kg dose per day) has an effect to the average of the diameter size alba pulp of the spleen in OVA-induced Balb/C mice significantly. 700mg/kg dose per day has the same effect with the methylprednisolone group. Keywords: immunomodulator, Carica papaya L., alba pulp of the spleen, ovalbumin


Author(s):  
Wardati Humaira

One technique that can be applied to increase assertiveness is assertiveness training. This study aims to determine the effect of assertive training techniques to increase assertiveness on sexual behavior in dating by using a pre-experimental approach with pre-test and post-test Control Group Design as well as non-probability sampling techniques and then analyzed by bivariate and multivariate analysis. The results of the independent sample t test for the level of assertiveness showed that the value of p = 0.001 with a test value of t = 7.394, which means that there is an effect of assertive technique training on the assertiveness level of adolescents in sexual behavior. The mean value in the provision of assertive technique training is known to be 4.09 and the mean value to the control is 0.36, this means that there is a change in the value of the assertiveness level of assertiveness towards sexual behavior in dating.


Author(s):  
Suyoto . ◽  
Farid Agushybana ◽  
Antono Suryoputro

Background: Based on data from WHO, it is estimated that 70% of the 57 million deaths that occurred in the world in 2008 were caused by non-communicable diseases. The prevalence of cases of hypertension primary in the District of Wonosobo in the year 2016 as many as 43.30%. Hypertension patients must take medication during their lifetime to prevent rising blood pressure and complications. This research aims to find out the effect of hypertension management through an android application on the practice of adherence to taking medication in hypertensive patients in Wonosobo regency.Methods: This research is a quasi-experimental with a non-randomized pre-post-test control group design. The study is conducted in patients prolanis hypertension as much as 105 respondents were divided into a treatment group 53 respondents and group control of 52 respondents.Results: Results of the study showed the significant influence of the use of android application to practice obedience to drink medicine. Results of Mann Whitney U analysis showed the treatment group experienced a rise in the mean is higher than the group of control. Likewise, the results of the test Wilcoxon which compares the level of compliance before and after treatment obtained value significantly for both groups with a mean group of treatment is higher.Conclusions: The management of hypertension through an android application has proven to be more effective in improving the practice of adherence to taking medication hypertension patients who take part in the prolanis program in Wonosobo regency.


Author(s):  
Sestia Rani ◽  
Rosfita Rasyid ◽  
Desmawati Desmawati

Background: Anemia is one of four nutritional problems in Indonesia with a prevalence of 21.7%, the type of anemia is iron deficiency anemia. One of the causes of iron by tannins present in green tea. The purpose of this study is to determine the effect of green tea on hemoglobin and hematocrit amount in Rattus novergicus strain wistar albino.Methods: This research used experiment with post-test only control group design. Twenty four rats were divided into four groups: the control group and the treatment group were given a different dose of 5.6g in a 1.8ml/200gr solvent, 8.4g in a 1.8ml/200g solvent, 11.2g in 1.8ml/200gr solvent for a month. Blood is taken through 2 ml orbital sinus using capillary pipette. hemoglobin examination using spectrophotometer and hematocrit checking using microhematocrit tool. The study was conducted in pharmaceutical laboratories and biochemical laboratories. Data analysis using one way ANOVA and Kruskal Wallis with degree of significance p<0.05.Results: The results of the study were found the mean differences amount of hemoglobin and hematocrit. The mean of control group in hemoglobin content was 16.39gr%, in treatment group were P1: 13.64gr%, P2: 11.19gr% and P3: 10.49 gr%, while in hematocrit control group was 44.83%, in treatment group were P1: 44.83%, P2: 39.17% and P3: 37.17%. Result of the test using one way ANOVA, which found the effect of green tea on hemoglobin (p value = 0.000) and result of the test using Kruskal-Wallis, which found the effect of green tea on hematocrit (p value = 0.017).Conclusions: Based on the results of this study concluded that there is influence of green tea on the decrease of hemoglobin and hematocrit amount in Rattus novergicus strain wistar albino. It is suggested to pay more attention to dose of green tea with normal limit of 8.4gr.


2021 ◽  
Vol 4 (1) ◽  
pp. 27-36
Author(s):  
Witri Hastuti ◽  
Sri Pujiwati ◽  
Retno Apriliyanti

Neonates in perinatology room of Wongsonegoro Hospital were 879 babies from August 2019 to July 2020 and 459 (52%) had infusions attached. Total of 459 infants were given intravenous lines, found 11 (2,3%) cases of failure in infusion. Failure causes the neonates cry because of pain. Based on this, the purpose of this study was to determine the effect of giving breastmilk and dextrose 55 %% on the pain response during infusion in neonates. This type of research is quasi experiment. The design of this study used a posttest with control group design. Population was neonates who received infusion therapy. Sampel of 32 neonates. The treatment group was given breast milk for 16 neonates and the control group was given Dextrose 5% for 16 neonates. This study used purposive sampling. The statistical test used the Mann Whitnesy test. The pain response of the breast milk treatment group in neonates was the mean value of 3.19. Pain response in the control group was the mean value of 4.31. There is an effect of giving breast milk the pain response during infusion in nenates p value=0.002. So it can be concluded that giving breast milk is more effective in reducing pain during infusion in neonates when compared to dextrose 5%.


2020 ◽  
Vol 3 (2) ◽  
pp. 436-445
Author(s):  
Mochamad Heri ◽  
Putu Karisma Dewi ◽  
Gede Budi Widiarta ◽  
Made Martini

This study aims to determine the effect of psychoeducation therapy on increasing self-efficacy in families with pulmonary TB disease at Kertha Usada General Hospital. Method: The research design used quasi-experimental with pre-post test with control group design. Results: The results showed the mean (mean) pre-test in the treatment group was 20.56 and in the control group was 21.04. The mean post-test mean in the treatment group was 31.51 and in the control group, the results were 30.57. Parametric test results using the Paired Sample T-test obtained p-value = (0,000) <α (0.05). Conclusion, there is an effect of psychoeducation therapy on increasing self-efficacy in families with Pulmonary of TB in Kertha Usada General Hospital.   Keywords: Self-Efficacy, Family Psychoeducation Therapy, Tuberculosis


2021 ◽  
Vol 8 (1) ◽  
pp. 69-78
Author(s):  
Rezah Andriani

One of the nonpharmacological therapies to trigger the performance of the oxytocin hormone for cervical ripening and acceleration of first stage labor is consuming fresh dates. Dates contain the oxytocin which can help stimulate contractions in the uterine muscles. Dates (Phoenix Dactylifera) contain carbohydrate can be directly absorbed by the body. Dates can be useful for labor, by consuming dates 60-70 grams per day at 4 weeks before giving birth to pregnant women it will be useful for cervical ripening and acceleration of first stage labor. The purpose of this study was to determine the effect of giving dates at the end of pregnancy on cervical ripening in pregnant women at PMB Ellna and Zuniawati in 2020. This study used a quantitative approach, the method was a quasi-experimental type of posttest control group design. The result the mean bishop score in the treatment group (11.1) was higher than control group (8.6). The mean duration of the first stage labor in the treatment group(231.1 minutes) was faster than control group (297.8 minutes). Statistically there was a significant difference in the bishop score and the duration of the first stage labor between the treatment group and the control group p <0.05.


Sign in / Sign up

Export Citation Format

Share Document