Interaction between a history of depression and rumination on neural response to emotional faces

BackgroundBoth past depressive episodes and the personality trait of depressive rumination are strong risk factors for future depression. Depression is associated with abnormal emotional processing, which may be a neurobiological marker for vulnerability to depression. A consistent picture has yet to emerge as to how a history of depression and the tendency to ruminate influence emotional processing. The aim of this study was to investigate the relationship between rumination, past depression and neural responses when processing face emotions.MethodThe Ruminative Responses Scale (RRS) was completed by 30 remitted depressives and 37 controls who underwent functional magnetic resonance imaging (fMRI) scanning while viewing happy, sad, fearful and neutral faces.ResultsThe remitted depressives showed overall reductions in neural responses to negative emotions relative to the controls. However, in the remitted depressives, but not the controls, RRS scores were correlated with increased neural responses to negative emotions and decreased responses to happiness in limbic regions.ConclusionsAutomatic emotion processing biases and rumination seem to be correlated to aspects of vulnerability to depression. However, remission from depression may be maintained by a general suppression of limbic responsiveness to negative emotion.

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State-dependent alteration in face emotion recognition in depression

The British Journal of Psychiatry ◽

10.1192/bjp.bp.110.078139 ◽

2011 ◽

Vol 198 (4) ◽

pp. 302-308 ◽

Cited By ~ 65

Author(s):

Ian M. Anderson ◽

Clare Shippen ◽

Gabriella Juhasz ◽

Diana Chase ◽

Emma Thomas ◽

...

Keyword(s):

Emotion Recognition ◽

Emotional Processing ◽

Recognition Task ◽

Control Group ◽

State Dependent ◽

Depressed Group ◽

History Of ◽

Remitted Depression ◽

Face Emotion Recognition ◽

History Of Depression

BackgroundNegative biases in emotional processing are well recognised in people who are currently depressed but are less well described in those with a history of depression, where such biases may contribute to vulnerability to relapse.AimsTo compare accuracy, discrimination and bias in face emotion recognition in those with current and remitted depression.MethodThe sample comprised a control group (n = 101), a currently depressed group (n = 30) and a remitted depression group (n = 99). Participants provided valid data after receiving a computerised face emotion recognition task following standardised assessment of diagnosis and mood symptoms.ResultsIn the control group women were more accurate in recognising emotions than men owing to greater discrimination. Among participants with depression, those in remission correctly identified more emotions than controls owing to increased response bias, whereas those currently depressed recognised fewer emotions owing to decreased discrimination. These effects were most marked for anger, fear and sadness but there was no significant emotion × group interaction, and a similar pattern tended to be seen for happiness although not for surprise or disgust. These differences were confined to participants who were antidepressant-free, with those taking antidepressants having similar results to the control group.ConclusionsAbnormalities in face emotion recognition differ between people with current depression and those in remission. Reduced discrimination in depressed participants may reflect withdrawal from the emotions of others, whereas the increased bias in those with a history of depression could contribute to vulnerability to relapse. The normal face emotion recognition seen in those taking medication may relate to the known effects of antidepressants on emotional processing and could contribute to their ability to protect against depressive relapse.

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Quality of parenting and vulnerability to depression: results from a family study

Psychological Medicine ◽

10.1017/s0033291797006016 ◽

1998 ◽

Vol 28 (1) ◽

pp. 185-191 ◽

Cited By ~ 64

Author(s):

C. DUGGAN ◽

P. SHAM ◽

C. MINNE ◽

A. LEE ◽

R. MURRAY

Keyword(s):

Mental Illness ◽

Family Study ◽

Past History ◽

Familial Risk ◽

Self Report ◽

History Of ◽

Quality Of Parenting ◽

Independent Effects ◽

The Relationship ◽

History Of Depression

Background. We examined a group of subjects at familial risk of depression and explored the relationship between the perceptions of parents and a history of depression. We also investigated: (a) whether any difference in perceived parenting found between those with and without a past history of depression was an artefact of the depression; and (b) whether the relationship between parenting and depression was explained by neuroticism.Method. We took a sample of first-degree relatives selected from a family study in depression and subdivided them by their history of mental illness on the SADS-L, into those: (a) without a history of mental illness (N=43); and (b) those who had fully recovered from an episode of RDC major depression (N=34). We compared the perceptions of parenting, as measured by the Parental Bonding Instrument (PBI), in these two groups having adjusted for the effect of neuroticism and subsyndromal depressive symptoms. We also had informants report on parenting of their siblings, the latter being subdivided into those with and without a past history of depression.Results. Relatives with a past history of depression showed lower care scores for both mother and father combined compared with the never ill relatives. The presence of a history of depression was associated with a non-significant reduction in the self-report care scores compared to the siblings report. Vulnerable personality (as measured by high neuroticism) and low perceived care were both found to exert independent effects in discriminating between the scores of relatives with and without a history of depression and there was no interaction between them.Conclusion. This study confirmed that low perceived parental care was associated with a past history of depression, that it was not entirely an artefact of having been depressed, and suggested that this association was partially independent of neuroticism.

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Neural responses during down-regulation of negative emotion in patients with recently diagnosed bipolar disorder and their unaffected relatives

Psychological Medicine ◽

10.1017/s0033291721002737 ◽

2021 ◽

pp. 1-12

Author(s):

Hanne Lie Kjærstad ◽

Julian Macoveanu ◽

Gitte Moos Knudsen ◽

Sophia Frangou ◽

K. Luan Phan ◽

...

Keyword(s):

Bipolar Disorder ◽

Emotion Regulation ◽

Functional Connectivity ◽

Neural Activity ◽

Negative Emotion ◽

Negative Emotions ◽

Imaging Study ◽

Neural Responses ◽

Functional Magnetic Resonance ◽

Down Regulation

Abstract Background Aberrant emotion regulation has been posited as a putative endophenotype of bipolar disorder (BD). We therefore aimed to compare the neural responses during voluntary down-regulation of negative emotions in a large functional magnetic resonance imaging study of BD, patients' unaffected first-degree relatives (URs), and healthy controls (HCs). Methods We compared neural activity and fronto-limbic functional connectivity during emotion regulation in response to aversive v. neutral pictures in patients recently diagnosed with BD (n = 78) in full/partial remission, their URs (n = 35), and HCs (n = 56). Results Patients showed hypo-activity in the left dorsomedial, dorsolateral, and ventrolateral prefrontal cortex (DMPFC and DLPFC) during emotion regulation while viewing aversive pictures compared to HCs, with URs displaying intermediate neural activity in these regions. There were no significant differences between patients with BD and HCs in functional connectivity from the amygdala during emotion regulation. However, exploratory analysis indicated that URs displayed more negative amygdala–DMPFC coupling compared with HCs and more negative amygdala-cingulate DLPFC coupling compared to patients with BD. At a behavioral level, patients and their URs were less able to dampen negative emotions in response aversive pictures. Conclusions The findings point to deficient recruitment of prefrontal resources and more negative fronto-amygdala coupling as neural markers of impaired emotion regulation in recently diagnosed remitted patients with BD and their URs, respectively.

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Differences in neural and cognitive response to emotional faces in middle-aged dizygotic twins at familial risk of depression

Psychological Medicine ◽

10.1017/s0033291717000861 ◽

2017 ◽

Vol 47 (13) ◽

pp. 2345-2357 ◽

Cited By ~ 2

Author(s):

K. W. Miskowiak ◽

A. M. B. Svendsen ◽

C. J. Harmer ◽

R. Elliott ◽

J. Macoveanu ◽

...

Keyword(s):

High Risk ◽

Face Processing ◽

Familial Risk ◽

Risk Groups ◽

Low Risk ◽

Middle Aged ◽

Emotional Faces ◽

Dizygotic Twins ◽

History Of ◽

History Of Depression

BackgroundNegative bias and aberrant neural processing of emotional faces are trait-marks of depression but findings in healthy high-risk groups are conflicting.MethodsHealthy middle-aged dizygotic twins (N = 42) underwent functional magnetic resonance imaging (fMRI): 22 twins had a co-twin history of depression (high-risk) and 20 were without co-twin history of depression (low-risk). During fMRI, participants viewed fearful and happy faces while performing a gender discrimination task. After the scan, they were given a faces dot-probe task, a facial expression recognition task and questionnaires assessing mood, personality traits and coping.ResultsUnexpectedly, high-risk twins showed reduced fear vigilance and lower recognition of fear and happiness relative to low-risk twins. During face processing in the scanner, high-risk twins displayed distinct negative functional coupling between the amygdala and ventral prefrontal cortex and pregenual anterior cingulate. This was accompanied by greater fear-specific fronto-temporal response and reduced fronto-occipital response to all emotional faces relative to baseline. The risk groups showed no differences in mood, subjective state or coping.ConclusionsLess susceptibility to fearful faces and negative cortico-limbic coupling during emotional face processing may reflect neurocognitive compensatory mechanisms in middle-aged dizygotic twins who remain healthy despite their familial risk of depression.

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Relationship between progression of brain white matter changes and late-life depression: 3-year results from the LADIS study

The British Journal of Psychiatry ◽

10.1192/bjp.bp.111.098897 ◽

2012 ◽

Vol 201 (1) ◽

pp. 40-45 ◽

Cited By ~ 53

Author(s):

Michael J. Firbank ◽

Andrew Teodorczuk ◽

Wiesje M. Van Der Flier ◽

Alida A. Gouw ◽

Anders Wallin ◽

...

Keyword(s):

White Matter ◽

Depression Scale ◽

Late Life ◽

The Elderly ◽

Late Life Depression ◽

White Matter Changes ◽

Brain White Matter ◽

History Of ◽

Depressive Episodes ◽

History Of Depression

BackgroundBrain white matter changes (WMC) and depressive symptoms are linked, but the directionality of this association remains unclear.AimsTo investigate the relationship between baseline and incident depression and progression of white matter changes.MethodIn a longitudinal multicentre pan-European study (Leukoaraiosis and Disability in the elderly, LADIS), participants aged over 64 underwent baseline magnetic resonance imaging (MRI) and clinical assessments. Repeat scans were obtained at 3 years. Depressive outcomes were assessed in terms of depressive episodes and the Geriatric Depression Scale (GDS). Progression of WMC was measured using the modified Rotterdam Progression scale.ResultsProgression of WMC was significantly associated with incident depression during year 3 of the study (P = 0.002) and remained significant after controlling for transition to disability, baseline WMC and baseline history of depression. There was no significant association between progression of WMC and GDS score, and no significant relationship between progression of WMC and history of depression at baseline.ConclusionsOur results support the vascular depression hypothesis and implicate WMC as causal in the pathogenesis of late-life depression.

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Gangguan Depresi Mayor: Mini Review

Health Information : Jurnal Penelitian ◽

10.36990/hijp.v9i1.102 ◽

2017 ◽

Vol 9 (1) ◽

pp. 34-49 ◽

Cited By ~ 5

Author(s):

Indriono Hadi ◽

Fitri Wijayanti ◽

Reni Devianti Usman ◽

Lilin Rosyanti

Keyword(s):

Life Stress ◽

Genetic Factors ◽

Usual Activity ◽

Neural Responses ◽

Social Psychological ◽

Major Depressive ◽

Susceptibility Factors ◽

History Of ◽

The Brain ◽

History Of Depression

Depression is a condition of a person feeling sad, disappointed when experiencing a change, loss, failure and becoming pathological when unable to adapt. Depression is a condition that affects a person affectively, physiologically, cognitively and behaviorally thus changing the usual patterns and responses. Major Depressive Disorder is a heterogeneous disease characterized by feelings of depression, anhedonia, changes in cognitive function, changes in sleep, changes in appetite, guilt that occur over two weeks, described with a loss of interest or pleasure in the usual activity and is a disease with neurobiological consequences involving structural, functional and molecular changes in some areas of the brain. Maladaptive neural responses, social, psychological, and physiological rejections interact with each other with other susceptibility factors, such as a history of depression, life stress levels, genetic factors, will increase a person's susceptibility to depression. Catatan PenerbitPolekkes Kemenkes Kendari menyatakan tetap netral sehubungan dengan klaim dari perspektif atau buah pikiran yang diterbitkan dan dari afiliasi institusional manapun.

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Relationship Between Disease-Modifying Therapy and Depression in Multiple Sclerosis

International Journal of MS Care ◽

10.7224/1537-2073.2012-036 ◽

2013 ◽

Vol 15 (3) ◽

pp. 107-112 ◽

Cited By ~ 7

Author(s):

Stephen S. Kirzinger ◽

Jason Jones ◽

Angela Siegwald ◽

Andrew Bryce Crush

Keyword(s):

Multiple Sclerosis ◽

Initial Therapy ◽

Score Change ◽

Disease Modifying Therapy ◽

Disease Modifying Therapies ◽

Relapsing Remitting ◽

History Of ◽

Disease Modifying ◽

The Relationship ◽

History Of Depression

Many prescribers of disease-modifying therapies (DMTs) for multiple sclerosis (MS) believe that interferon beta (IFNβ) is more likely than glatiramer acetate (GA) to increase depression during the course of MS treatment. Therefore, newly diagnosed patients with a history of depression are often placed on GA therapy from the onset of MS treatment. The aim of this study was to examine the relationship between DMT type and depression among patients with relapsing-remitting MS (RRMS). Patients with RRMS who were examined from 2000 to 2007 and who remained on a single course of therapy (either an IFNβ or GA) were included in a retrospective review of medical records. Patients were asked to complete the Beck Depression Inventory (BDI) at treatment initiation and every 6 months thereafter for up to 4 years. Only patients who had completed a BDI within 6 weeks of starting their DMT were included in the analysis. No significant differences in mean change in BDI score were observed from baseline to 48 months between the IFNβ and GA subgroups. Additionally, no significant differences in mean BDI score change were observed between antidepressant-treated and non–antidepressant-treated patients within the IFNβ or GA subgroup. Neither IFNβ nor GA therapy appears to exacerbate depressive symptoms in patients with RRMS who remain on their initial therapy.

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Prefrontal BOLD Responses Coupled to Changing Emotional Faces in Adolescents with and without a History of Suicide Attempt

Journal of Medical Psychology ◽

10.3233/jmp-180018 ◽

2020 ◽

Vol 1 (1) ◽

pp. 43-52 ◽

Cited By ~ 1

Author(s):

Henry W. Chase ◽

Anna Maria Segreti ◽

Jay C. Fournier ◽

Mary L. Phillips ◽

David Brent ◽

...

Keyword(s):

Suicide Attempt ◽

Functional Neuroimaging ◽

Emotion Processing ◽

Blood Oxygenation ◽

Neural Function ◽

Healthy Controls ◽

Emotional Faces ◽

Bold Responses ◽

History Of ◽

History Of Depression

Background: Functional abnormalities in emotion processing neural circuitry in adolescents with a history of suicide attempt relative to depressed adolescents with no history of suicide and healthy controls have been identified, typically utilizing static face presentations. Objective: The objective of the present work was to characterize functional activations associated with emotional face processing in adolescents with and without a history of suicide attempt. Methods: 64 adolescents including 19 with a history of depression and suicide attempt (ATT), 22 with a history of depression but no suicide attempt (NAT) and 23 healthy controls (HC) performed an implicit emotional-faces task during functional neuroimaging, in which they identified a color label superimposed on neutral faces that dynamically morphed into one of four emotional faces (angry, fearful, sad, and happy). Results: HC showed greater Blood Oxygenation Level Dependent (BOLD) responses compared with ATT in the Right Dorsolateral Prefrontal Cortex (rDLPFC) to all emotional faces compared to shapes. A similar pattern of group differences was seen when both ATT and NAT groups were compared with HC. Across all participants, an association between child trauma and rDLPFC activation was seen, although this was not corrected for multiple comparisons. Conclusions: Together, the findings are consistent with prior observations of emotion-related alterations in neural function in suicide attempters. However, they also suggest that adequate control groups are necessary to dissociate specific correlates of suicide risk from depression or trauma severity, which may contribute to prefrontal alterations in emotion processing.

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Obstructive sleep apnea is associated with depressive symptoms in pregnancy

SLEEP ◽

10.1093/sleep/zsz270 ◽

2019 ◽

Vol 43 (5) ◽

Author(s):

Karen Redhead ◽

Jennifer Walsh ◽

Megan Galbally ◽

John P Newnham ◽

Stuart J Watson ◽

...

Keyword(s):

Obstructive Sleep Apnea ◽

Depressive Symptoms ◽

Sleep Apnea ◽

Apnea Hypopnea Index ◽

Targeted Interventions ◽

Obstructive Sleep ◽

History Of ◽

Depressive Episodes ◽

History Of Depression ◽

In Pregnancy

Abstract Study Objectives In pregnancy, the prevalence of both obstructive sleep apnea (OSA) and depression increases. Research reveals an association in the general population with up to 45% of patients diagnosed with OSA having depressive symptoms. Therefore, this study aimed to investigate the relationship between OSA and depression in pregnant women. Methods One hundred and eighty-nine women ≥26 weeks pregnant were recruited from a tertiary perinatal hospital. This cross-sectional study measured OSA (Apnea Hypopnea Index, AHI, using an ApneaLink device) and symptoms of depression (Edinburgh Postnatal Depression Scale, EPDS). Data were collected from medical records including participant age, ethnicity, parity, BMI, smoking status, history of depression, and use of antidepressants. Results Of the consenting women, data from 124 were suitable for analysis. Twenty women (16.1%) had OSA (AHI ≥ 5 events/h) and 11 (8.8%) had depressive symptoms (EPDS > 12). Women with OSA were more likely to have depressive symptoms after adjusting for covariates, odds ratio = 8.36, 95% CI [1.57, 44.46]. OSA was also related to higher EPDS scores and these were greater in women with a history of depression. Conclusions During late pregnancy women with OSA had eight times the odds of having depressive symptoms. Furthermore, an interaction was found between OSA and history of depression. Specifically, in women with no history of depression, OSA increases depressive symptoms. In women with a history of depression, OSA has an even stronger effect on depressive symptomology. This suggests screening for OSA in pregnancy may identify women prone to future depressive episodes and allow for targeted interventions.

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How emotions affect restaurant digital ordering experiences: a comparison of three ordering methods

Journal of Hospitality and Tourism Technology ◽

10.1108/jhtt-05-2020-0117 ◽

2021 ◽

Vol ahead-of-print (ahead-of-print) ◽

Author(s):

Xi Y. Leung ◽

Han Wen

Keyword(s):

Positive Emotions ◽

Negative Emotion ◽

Negative Emotions ◽

Restaurant Industry ◽

Content Type ◽

Different Types ◽

Expectancy Disconfirmation ◽

Quick Service ◽

The Relationship

Purpose The purpose of this study is to examine the role of consumption emotion in the digital food-ordering experience by comparing the performances of the three digital ordering methods in an experimental design. Design/methodology/approach A research model was developed based on the Feelings-as-Information (FaI) theory and the expectancy-disconfirmation theory. A 3 × 2 between-subjects lab experiment was conducted to compare the three digital ordering methods (online, mobile or chatbot) in two different types of restaurants (quick-service or full-service). Findings The results indicate that the chatbot ordering method evoked more negative emotions and less positive emotions than the other two methods. The online ordering method worked the best for quick-service restaurants, whereas the mobile ordering method was most suitable for full-service restaurants. Both positive and negative emotions (comfort and annoyance) significantly mediated the relationships between the ordering method and internal responses (satisfaction and behavioral intention). Only one negative emotion (anger) significantly mediated the relationship between the ordering method and order amount. Originality/value This is the first study that attempts to explore and compare consumers’ emotional responses resulting from restaurant digital ordering experiences in the context of the three food-ordering methods. The use of the FaI theory strengthens the theoretical foundation of research on emotion in the hospitality field. This study also pioneers the application of chatbot technology in the restaurant industry.

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