scholarly journals Cardiovascular health and cognitive functioning among centenarians: a comparison between the Tokyo and Georgia centenarian studies

2019 ◽  
Vol 31 (04) ◽  
pp. 455-465 ◽  
Author(s):  
Peter Martin ◽  
Yasuyuki Gondo ◽  
Yasumichi Arai ◽  
Yoshiko Ishioka ◽  
Mary Ann Johnson ◽  
...  
Keyword(s):  
United States ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Cognitive Functioning ◽  
Cardiovascular Health ◽  
The United States ◽  
C Reactive Protein ◽  
Differential Effects ◽  
Reactive Protein ◽  
Positive Effects

ABSTRACTObjectives:Centenarians have survived into very late life, but whether they reach very old age in good health remains unclear. The purpose of this study was to compare the cardiovascular health status and cognitive functioning of centenarians in the United States with centenarians in Japan.Design, Setting, and Participants:This cross-national design compared centenarians from the United States and Japan. The sample of U.S. centenarians was recruited from the Georgia Centenarian Study and included 287 centenarians. The sample of Japanese centenarians was recruited from the Tokyo Centenarian Study and included 304 centenarians.Measurements:Cognitive functioning was assessed with a mental status questionnaire, and cardiovascular disease by a health history assessment, blood pressure, and selected blood parameters.Results:The results suggest that Tokyo centenarians had lower disease experiences and BMI values, when compared to Georgia centenarians, but blood pressure was higher among Japanese centenarians. Lower levels of hemoglobin in Japanese centenarians and higher levels of C-reactive protein in Georgia were also found. The positive association of hypertension and albumin levels with cognitive functioning and the negative association of stroke occurrence with cognitive functioning were replicated in both countries. Differential effects were obtained for heart problems, BMI, and C-reactive protein (with positive effects for Tokyo centenarians, except for C-reactive protein).Conclusion:For extremely old individuals, some markers of cardiovascular disease are replicable across countries, whereas differential effects for cardiovascular health also need to be considered in cardiovascular health.

scholarly journals PREVENTIVE CARDIOLOGY, PRECLINICAL DIAGNOSES: OLD PROBLEMS – NEW APPROACHES

2017 ◽  
Vol 4 (1) ◽  
pp. 5-8
Author(s):  
T.V. Ashcheulova ◽  
O.A Kochubiei O.A ◽  
T.G. Ovrakh
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Inflammatory Markers ◽  
C Reactive Protein ◽  
Preventive Cardiology ◽  
Reactive Protein ◽  
Novel Approaches ◽  
New Guidelines

PREVENTIVE CARDIOLOGY, PRECLINICAL DIAGNOSES: OLD PROBLEMS – NEW APPROACHESAshcheulova T.V., Kochubiei O.A., Ovrakh T.GThe article discusses the new Guidelines on cardiovascular disease prevention in clinical practice (2016) which summarized novel approaches of detection of such risk factors as overweigh, obesity, abdominal obesity, smoking, dyslipidemia (cholesterolemia, triglyceridemia), blood pressure (BP) levels, glucose, insulin, insulin resistance, inflammatory markers, such as c-reactive protein, which can be widely used in practice.KeyWords: Cardiovascular disease, preventive cardiology, risk assessment and stratification, strategy for prevention of cardiovascular diseases. ПРЕВЕНТИВНА КАРДІОЛОГІЯ, ДОКЛІНІЧНА ДІАГНОСТИКА: СТАРІ ПРОБЛЕМИ - НОВІ ПІДХОДИАщеулова Т.В., Кочубєй О.А., Оврах Т.Г. У статті розглядаються нові рекомендації з профілактики серцево-судинних захворювань в клінічній практиці (2016 г.), що узагальнюють нові підходи виявлення таких факторів ризику, як надмірна маса тіла, ожиріння, абдомінальне ожиріння, куріння, дисліпідемія (холестеринемія, тригліцеридемія),  артеріальний тиск (АТ), рівень глюкози, інсуліну, резистентність до інсуліну, запальні маркери, такі як С-реактивний білок, які можуть знайти широке застосування у практичній охороні здоров’я.Ключові слова: Серцево-судинні захворювання, профілактична кардіологія, оцінка і стратифікація ризику, стратегія профілактики серцево-судинних захворювань. ПРЕВЕНТИВНАЯ КАРДИОЛОГИЯ, ДОКЛИНИЧЕСКАЯ ДИАГНОСТИКА: СТАРЫЕ ПРОБЛЕМЫ - НОВЫЕ ПОДХОДЫАщеулова Т.В., Кочубей О.А., Оврах Т.Г. В статье рассматриваются новые рекомендации по профилактике сердечно-сосудистых заболеваний в клинической практике (2016 г.), обобщены новые подходы выявления таких факторов риска, как избыточная масса тела, ожирение, абдоминальное ожирение, курение, дислипидемия (холестеринемия, гипертриглицеридемия), повышение артериального давления, уровень глюкозы, инсулина, резистентность к инсулину, маркеры воспаления, такие как С-реактивный белок, которые могут найти широкое применение в практическом здравоохранении.Ключевые слова: сердечно-сосудистые заболевания, профилактическая кардиология, оценка и стратификация риска, стратегия профилактики сердечно-сосудистых заболеваний. 

Identifying Properties for an Aortic Stent-Graft That Counteracts Hypertension

2018 ◽  
Author(s):  
Shannen B. Kizilski ◽  
Omid Amili ◽  
Filippo Coletti ◽  
Rumi Faizer ◽  
Victor H. Barocas
Keyword(s):  
United States ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Risk Factor ◽  
Stent Graft ◽  
American Heart Association ◽  
American Heart ◽  
Heart Association ◽  
The United States ◽  
Aortic Stent Graft

In 2017, the American Heart Association reported that one third of deaths in the United States, and 31% of deaths worldwide, are attributed to cardiovascular disease (CVD) [1]. A risk factor pervasive across most types of CVD is chronic high blood pressure, or hypertension [2].

Abstract 16562: Association of County-Level Social Vulnerability Index and Cardiovascular Disease in the United States, 1999-2018

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Quentin R Youmans ◽  
Megan E McCabe ◽  
Clyde W Yancy ◽  
Lucia Petito ◽  
Kiarri N Kershaw ◽  
...  
Keyword(s):  
United States ◽  
Cardiovascular Disease ◽  
Social Vulnerability ◽  
Cardiovascular Health ◽  
Vulnerability Index ◽  
The United States ◽  
County Level ◽  
Social Vulnerability Index ◽  
Cross Sectional ◽  
Cvd Mortality

Introduction: Social determinants of health are multi-dimensional and span various interrelated domains. In order to inform community-engaged clinical and policy efforts, we sought to examine the association between a national social vulnerability index (SVI) and age-adjusted mortality rate (AAMR) of CVD. Hypothesis: Higher county-level SVI or greater vulnerability will be associated with higher AAMR of CVD between 1999-2018 in the United States. Methods: In this serial, cross-sectional analysis, we queried CDC WONDER for age-adjusted mortality rates (AAMRs) per 100,000 population for cardiovascular disease (I00-78) at the county-level between 1999-2018. We quantified the association of county-level SVI and CVD AAMR using Spearman correlation coefficients and examined trends in CVD AAMR stratified by median SVI at the county-level. Finally, we performed geospatial county-level analysis stratified by combined median SVI and CVD AAMR (high/high, high/low, low/high, and low/low). Results: We included data from 2766 counties (representing 95% of counties in the US) with median SVI 0.53 (IQR 0.28, 0.76). Overall SVI and the household and socioeconomic subcomponents were strongly correlated with 2018 CVD AAMR (0.47, 0.50, and 0.56, respectively with p<0.001 for all). CVD mortality declined between 1999-2011 and was stagnant between 2011-2018 with similar patterns in high and low SVI counties (FIGURE). Counties with high SVI and CVD AAMR were clustered in the South and Midwest (n=977, 35%). Conclusion: County-level social vulnerability is associated with higher CVD mortality. High SVI and CVD AAMR coexist in more than 1 in 3 US counties and have persisted over the past 2 decades. Identifying counties that are disproportionately vulnerable may inform targeted and community-based strategies to equitably improve cardiovascular health across the country.

Acute Hemodynamic Responses to Combined Exercise and Sauna

2020 ◽  
Vol 41 (12) ◽  
pp. 824-831 ◽  
Author(s):  
Joonas Antero Rissanen ◽  
Keijo Häkkinen ◽  
Jari Antero Laukkanen ◽  
Arja Häkkinen
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Endurance Exercise ◽  
Plasma Volume ◽  
Blood Cells ◽  
White Blood Cells ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Positive Effects ◽  
Volume Measurements

AbstractThis study investigated acute hemodynamic, plasma volume and immunological responses to four loading protocols: sauna only, and sauna after endurance, strength or combined endurance and strength exercise. Twenty-seven healthy, slightly prehypertensive men (age 32.7±6.9 years) were measured at PRE, MID (after exercise), POST, POST30min and POST24h. The measurements consisted systolic and diastolic blood pressure, heart rate, body temperature and concentrations of high-sensitive C-reactive protein, white blood cells and plasma volume measurements. Endurance+sauna showed significant decreases in systolic blood pressure at POST (–8.9 mmHg), POST30min (–11.0 mmHg) and POST24h (–4.6 mmHg). At POST30min, significant decreases were also observed in sauna (–4.3 mmHg) and combined+sauna (–7.5 mmHg). Diastolic blood pressure decreased significantly from -5.4 to –3.9 mmHg at POST in all loadings. Plasma volume decreased significantly at MID in all exercise loadings and at POST in endurance+sauna and strength+sauna. Plasma volume increased significantly (p < 0.01) in endurance+sauna and combined+sauna at POST24h. White blood cells increased following all exercise+sauna loadings at MID, POST and POST30min, whereas high sensitive C-reactive protein showed no changes at any measurement point. The combination of endurance exercise and sauna showed the greatest positive effects on blood pressure. Both loadings including endurance exercise increased plasma volume on the next day.

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