Risk factors for mild behavioral impairment in non-demented geriatrics: a population-based survey in Taiwan

2021 ◽  
pp. 1-9
Author(s):  
Yee-Lam E. Chan ◽  
Chih-Ming Cheng ◽  
Mao-Hsuan Huang ◽  
Huey-Jane Lee ◽  
Li-Yu Tang ◽  
...  

Abstract Objectives: To investigate potential risk factors for mild behavioral impairment (MBI) among non-demented geriatrics. Design: Population-based, cross-sectional survey. Setting: Taiwan Alzheimer Disease Association (TADA) Database. Participants: Participants were selected by multistage random sampling of all Taiwan counties. They received in-person interviews between December 2011 and March 2013. Measurements: Demographic data, lifestyle and habits, medical comorbidities, cognitive status measured by the Taiwanese Mini-Mental Status Examination (TMSE) and presence of MCI of the participants were collected. Subjects were distributed to the MBI and non-MBI groups. These factors had been evaluated for their effects on MBI in the univariate and multivariable logistic regression models. Results: In total, 6,196 non-demented participants aged 65 years or older, including 409 MBI and 5,787 non-MBI participants, were recruited. After adjustment for age, sex, education, body mass index, lifestyle and habits, medical comorbidities, and MCI, good sleep was associated with lower risk of MBI (OR 0.09, 95% CI 0.07 – 0.12). Low body weight (OR 2.01, 95% CI 1.21–3.33), low-to-medium education (OR 1.40, 95%CI 1.06–1.85; OR 2.32, 95% CI 1.67–3.21), medical comorbidities of hypertension (OR 1.56, 95% CI 1.25–1.95), hyperlipidemia (OR 1.29, 95% CI 1.00–1.67), cancer (OR 2.05, 95% CI 1.37–3.06) were significantly associated with increased MBI risk. MCI neither increased nor decreased risk of MBI (OR 1.00, 95% CI 0.76–1.32). Conclusions: Good sleep was associated with lower MBI risk. Underweight, lower education, medical comorbidities of cancer, hypertension, hyperlipidemia were predictive of MBI.

Neurology ◽  
2019 ◽  
Vol 93 (10) ◽  
pp. e984-e994 ◽  
Author(s):  
Adriano Chiò ◽  
Cristina Moglia ◽  
Antonio Canosa ◽  
Umberto Manera ◽  
Rosario Vasta ◽  
...  

ObjectiveTo assess the association of the degree of severity of motor impairment to that of cognitive impairment in a large cohort of patients with amyotrophic lateral sclerosis (ALS).MethodsThis is a population-based cross-sectional study on patients with ALS incident in Piemonte, Italy, between 2007 and 2015. Cognitive status was classified according to the revised ALS–FTD Consensus Criteria. The King system and the Milano Torino Staging system (MiToS) were used for defining the severity of motor impairment.ResultsOf the 797 patients included in the study, 163 (20.5%) had ALS–frontotemporal dementia (FTD), 38 (4.8%) cognitive and behavioral impairment (ALScbi), 132 (16.6%) cognitive impairment (ALSci), 63 (7.9%) behavioral impairment (ALSbi), 16 (2.0%) nonexecutive impairment, and 385 (48.2%) were cognitively normal. According to King staging, the frequency of cases with ALS-FTD progressively increased from 16.5% in stage 1–44.4% in stage 4; conversely, the frequency of ALSci, ALSbi, and ALScbi increased from King stage 1 to King stage 3 and decreased thereafter. A similar pattern was observed with the MiToS staging. ALS-FTD was more frequent in patients with bulbar involvement at time of cognitive testing. Patients with C9ORF72 expansion (n = 61) showed more severe cognitive impairment with increasing King and MiToS stages.ConclusionOur findings suggest that ALS motor and cognitive components may worsen in parallel, and that cognitive impairment becomes more pronounced when bulbar function is involved. Our data support the hypothesis that ALS pathology disseminates in a regional ordered sequence, through a cortico-efferent spreading model.


2019 ◽  
Vol 9 (4) ◽  
pp. 370-375
Author(s):  
Anthonia A. Ikpeme*,Nchiewe E. Ani, Edoise M. Isiwele, Andrew E. Ekpenyong,Emmanuel E. Ekanem

Introduction: Over 80% of cardiovascular deaths take place in low and middle incomecountries. These cardiovascular deaths are caused by modifiable risk factors. Evidenceis emerging that some of these factors maybe even more prevalent in rural areas whichare generally underserved.Aim: The aim of this study was to record risk factors for cardiovascular disease inrural communities in south southern Nigeria and review some related literature.Methods: A cross sectional study during clinical outreach activities that took placein 2016 to 2018 in several rural and few urban communities in Cross River State,Nigeria. Participating individuals gave full consent and ethical clearance obtained.Socio-demographic data, Anthropometric data and Blood sugar measurements wereobtained. Data extracted was transferred into EXCEL thereafter analysis was doneusing SPSS version 21. p values less than 0.05 were deemed statistically significant.Tests of significance included Anova, chi square and student t- tests.Results: Total population investigated over the 3 year period was 504. (2016-33.1%),(2017 -37.9%), (2018 – 28%) with a Female: Male distribution of 1:1.Most participants tended to be overweight across the years 59.7%, 59.1%, 73.7%,2016, 2017, and 2018 respectively. The prevalence of Hypertension was 10.71%. Nosignificant gender difference in the prevalence of Hypertension (6.94% males to 3.77%females, p=0.097). The prevalence of Diabetes Mellitus was 10.67%. There was nosignificant gender prevalence (6.67% males to 4.00% females, p =0.431)Conclusion: Cardiovascular disease remains relatively uncommon in Sub-SaharanAfrica, despite an increasing prevalence of risk factors, but it’s incidence is rising.Steps should be taken in Sub-Saharan Africa to prevent an epidemic. This involvesdetailed and regular screening for cardiovascular risk factors in rural communities.Key words: RISK FACTORS, Cardio vascular disease, South South Nigeria.


2021 ◽  
Vol 13 (7) ◽  
pp. 115
Author(s):  
Emilia Shiwa Ashipala ◽  
Linda Ndeshipandula Lukolo

INTRODUCTION: Hypertension complications are responsible for 9.4 million deaths worldwide and among these deaths, 51 % are due to stroke and 45% are due to heart disease like heart failure. This study aims to investigate the hypertension risk factors among adult in Oshikoto region, Namibia. METHODS: A community population-based, cross- sectional survey was conducted using WHO STEPwise approach among 375 adults in Oshikoto region. Bivariate and multivariate analysis was done to determine the association between risk factors and Hypertension, based on p-value <0.05. RESULTS: Overall prevalence for risk factors was: physical inactivity (25.3%), unhealthy diet (75.7%), tobacco use (9.1%), harmful use of alcohol (40.8%). 20.5% overweight with majority (85.7%) of them were females. Obesity was 9.1% in which 91.2% were females. Hypertension prevalence was 24.3%. Four percent of individuals were having two multiple risk factors for hypertension, 2.4% with four risk factors and 1.1% with more than four risk factors. Age group (OR=2.48, 95%CI=1.44-4.26, P=0.001), Obesity (OR=3.48, 95%CI=1.55-7.79, P=0.003), and overweight (OR=2.34, 95%CI=1.31-4.19, P =0.004) were significant risk factors for hypertension. CONCLUSIONS: This study revealed a high prevalence and burden of hypertension risk factors such as obesity and overweight among adults in Oshikoto region, thus, these results highlight the need for interventions to reduce and prevent those risk factors of hypertension in Oshikoto region, Namibia.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Amare Worku Tadesse ◽  
Elena C. Hemler ◽  
Christopher Andersen ◽  
Simone Passarelli ◽  
Alemayehu Worku ◽  
...  

Abstract Background Anemia remains a public health challenge in Ethiopia, affecting an estimated 56% of children under age 5 years, 23% of women of reproductive age and 18% of adult men. However, anemia etiology and the relative contribution of underlying risk factors for anemia remains unclear and has hindered implementation of anemia control programs. Methods/design Anemia Etiology in Ethiopia (AnemEE) is a population-based cross-sectional survey of six regions of Ethiopia that includes children, women of reproductive age, and men from regionally representative households. The survey will include detailed assessment of anemia, iron, inflammatory and nutritional biomarkers, diet, comorbidities, and other factors. The objectives of AnemEE are 1) to generate evidence for decision-making on the etiology of anemia in Ethiopia among men, women and children and 2) to simulate the potential effect of iron fortification and other interventions on the prevalence of anemia and risk of iron overload. Discussion AnemEE will provide the most comprehensive evaluation of anemia etiology in Ethiopia to date due to its detailed assessment of diet, biomarkers, infections and other risk factors in a population-based sample. By generating evidence and simulating potential interventions, AnemEE will inform the development of high-impact anemia control programs and policies. Trial registration ClinicalTrials.gov, NCT04002466. Registered on 28 June 2019. Retrospectively registered.


2007 ◽  
Vol 102 ◽  
pp. S512-S513
Author(s):  
Xuan Jiang ◽  
Giles R. Locke ◽  
Rok Seon Choung ◽  
Alan R. Zinsmeister ◽  
Cathy D. Schleck ◽  
...  

Author(s):  
Md. Imam Hossain ◽  
Masum Parvez ◽  
Fatama Tous Zohora ◽  
Md. Shariful Islam ◽  
Luthfunnesa Bari

Background: Asthmatic respiratory complications appear to be a notable public health consequence and associated with mortality, morbidity and economic burden worldwide. Globally several epidemiological studies have been conducted to assess the prevalence of asthmatic respiratory complications. As far our knowledge very few population based study have been conducted in Bangladesh to assess the magnitude of asthmatic respiratory complications focusing the rural community. Therefore the study was undertaken to assess the prevalence of asthma and related respiratory complications in the rural community of Tangail area in Bangladesh.Methods: This human population based cross-sectional survey study was conducted during the period of August to December 2016 on some villagers of Tangail area in Bangladesh using a pre-standardized questionnaires called "IUATLD -1984 bronchial symptoms questionnaires", designed by the International Union Against Tuberculosis and Lung Diseases (IUATLD). The demographic data of the study subjects were collected by interviewing the subjects and the data were analyzed using SPSS software.Results: The results demonstrated that a substantial proportion of study subjects showed the main characteristic symptoms of asthma i.e., wheeze last 12 months is about 18.27%, shortness of breath (SOB) without strenuous work were 21.84%, nocturnal SOB 14.70%, morning cough 13.26%, nocturnal cough 17.25% and morning phlegm 10.37%. Overall 9.69% of the subjects were found to be asthmatic. Female study subjects showed more asthmatic complications than male subjects and in the higher aged group asthmatic symptoms were more prevalent.Conclusions: Among the study subjects, asthmatic complications were found to be substantial. Further clinical study is necessary to confirm the findings.  


2021 ◽  
Vol 10 (13) ◽  
pp. e420101321441
Author(s):  
Marcel Gonçalves Maciel ◽  
Walter dos Santos Lima ◽  
Djane Clarys Baia da Silva ◽  
Rodolfo Silva Moreira Cezar ◽  
Josue Costa Oliveira ◽  
...  

Intestinal parasites are among the most prevalent infections in humans. A cross-sectional survey was performed in a Canutama, Amazonas state, Brazil, in order to estimate the prevalence of intestinal parasites. The detection of parasites in the feces was performed using the Lutz method. Demographic data and the characteristics of the households were collected using a questionnaire. The prevalence of parasites was 36.9%. Ascaris lumbricoides (7.14%) was the most prevalent. The absence of a sewage network, consumption of raw vegetables and raw meat are risk factors for contracting intestinal parasitosis. We reported a prevalence of intestinal parasites and determined some of the risk factors.


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