Recognizing & Treating Comorbid ADHD in Adults with Depression

CNS Spectrums ◽  
2009 ◽  
Vol 14 (S9) ◽  
pp. 11-14
Author(s):  
Michael J. Manos
Keyword(s):  
Adult Population ◽  
The United States ◽  
Major Depressive ◽  
Statistical Manual ◽  
National Comorbidity Survey Replication ◽  
Hyperactivity Disorder ◽  
Diagnostic And Statistical Manual ◽  
United States Population ◽  
The Us ◽  
Comorbid Adhd

The National Comorbidity Survey Replication by Kessler and colleagues found that of adult patients with major depressive disorder (MDD), 9.4% met Diagnostic and Statistical Manual of Mental Disorders, Third Edition-Revised criteria for attention-deficit/hyperactivity disorder (ADHD). Among those with dysthymia, 22.6% also met criteria for ADHD. In addition, it is estimated that approximately a third of the United States population experiences MDD symptoms at any point in time. Kessler and colleagues also conducted a retrospective study on impairment of adults with ADHD and found that ADHD has a prevalence of ∼4.4% in the US adult population, which suggests that ∼9 million US adults may have ADHD.

Major Depressive Disorder: Epidemiology, Course of Illness, and Treatment

CNS Spectrums ◽  
2008 ◽  
Vol 13 (S8) ◽  
pp. 4-7 ◽  
Author(s):  
Andrew A. Nierenberg
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Antidepressant Treatment ◽  
The United States ◽  
Epidemiologic Studies ◽  
Major Depressive ◽  
Course Of Illness ◽  
National Comorbidity Survey Replication ◽  
United States Population ◽  
Period 2

Understanding the epidemiology of major depressive disorder (MDD) and the neurobiologic theories behind depression and antidepressant treatment is vital for physicians who must identify and treat patients with this disorder. The epidemiology of MDD reveals that this disorder is widespread: the lifetime prevalence of MDD is estimated to be ∼17% and the 12-month prevalence is ≥7%, according to the National Comorbidity Survey Replication. Epidemiologic studies suggest that in any 30-day period, 2% to 5% of the United States population meet criteria for MDD. In addition, nearly twice as many women as men (21% versus 13%, respectively) are affected by a depressive disorder during their lifetimes. These numbers reveal a vast population of people affected by MDD, making depression a tremendous social and medical concern.

Introduction

CNS Spectrums ◽  
2007 ◽  
Vol 12 (S23) ◽  
pp. 4-5
Author(s):  
Lenard A. Adler ◽  
Jeffrey H. Newcorn
Keyword(s):  
Adult Adhd ◽  
The United States ◽  
Adhd Symptoms ◽  
Fourth Edition ◽  
Statistical Manual ◽  
Adhd Diagnosis ◽  
Text Revision ◽  
Hyperactivity Disorder ◽  
Diagnostic And Statistical Manual ◽  
Dsm Iv

Attention-deficit/hyperactivity disorder (ADHD) may be the most common chronic, undiagnosed psychiatric disorder in adults. ADHD is characterized by restlessness, overactivity, disorganization, impulsivity, and inattention; and as further characterized in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR). For most cases, an adult ADHD diagnosis is preceded by symptoms in childhood, which is a time when the disorder is rarely inquired about and usually overlooked.ADHD has been recognized in children for several decades, and the importance of detection and treatment is well established. Whereas it was initially believed that children outgrew the disease, researchers now know that approximately two thirds of children affected with ADHD symptoms carry the condition into adolescence and then into adulthood. Consequently, >4% of adults in the United States have ADHD. Nevertheless, the disorder is unrecognized and untreated in the vast majority of these people.

Abstract P183: 20-year Secular Trend of Cardiovascular Disease Comorbidities in the United States, 1997-2016

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Dianjianyi Sun ◽  
Tao Zhou ◽  
Xiang Li ◽  
Yoriko Heianza ◽  
Xiaoyun Shang ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Secular Trend ◽  
Adult Population ◽  
The United States ◽  
The Past ◽  
The Us ◽  
Metabolic Conditions ◽  
Respiratory Conditions ◽  
The U.S ◽  
Chronic Comorbidities

Background: Cardiovascular disease (CVD) has been the number one cause of death and disability in the US and globally for decades, and its comorbidity complicates the management of CVD. However, little is known about the secular trend of CVD comorbidities in national representative populations in the last 20 years. Methods: Prevalence of CVD and nine major chronic comorbidities was estimated using data from 1,324,214 adults aged 18 years and older in the National Health Interview Survey (NHIS) from 1997 through 2016, with age-standardized to the U.S. population in the year 2000. Results: CVD prevalence in the US adult population significantly declined in the past twenty years (from 6.6% in 1997 to 5.9% in 2016, P trend <0.01in Figure a). And such trend was shown in women and whites (P trend <0.01), but not in men and blacks (P trend >0.05). We ranked the nine major chronic comorbidities (high to low) in the CVD patients (Figure b.), including (1) hypertension, (2) respiratory conditions, (3) nervous system conditions, (4) digestive conditions, (5) diabetes, (6) cancer, (7) genitourinary conditions, (8) circulatory conditions, and (9) endocrine/nutritional/metabolic conditions. From 1997 to 2016, the prevalence of CVD comorbidities including hypertension (38.8% to 50.2%), digestive conditions (17.0% to 27.1%), diabetes (10.0% to 19.2%), cancer (9.4% to 12.8%), and genitourinary conditions (4.1% to 5.2%) continuingly increased (all P trend <0.01), while respiratory conditions declined (35.9% to 27.6%, P trend <0.01). Similar trends of CVD comorbidities were observed among subgroups stratified by gender or by race. Conclusions: CVD prevalence in the U.S. adults have declined significantly in the past two decades, but rates of CVD comorbidities including hypertension, digestive conditions, diabetes, cancer, and genitourinary conditions increased substantially.

scholarly journals Reaction time assessment in children with ADHD

2010 ◽  
Vol 68 (2) ◽  
pp. 282-286 ◽  
Author(s):  
Cristiana Bolfer ◽  
Erasmo Barbante Casella ◽  
Marcus Vinícius Chrysóstomo Baldo ◽  
Amanda Manzini Mota ◽  
Miriam Harumi Tsunemi ◽  
...  
Keyword(s):  
Reaction Time ◽  
Attention Deficit ◽  
Test Results ◽  
Voluntary Attention ◽  
Statistical Manual ◽  
Children With Adhd ◽  
Hyperactivity Disorder ◽  
Diagnostic And Statistical Manual ◽  
Attentional System ◽  
Normal Controls

Attention deficit, impulsivity and hyperactivity are the cardinal features of attention deficit hyperactivity disorder (ADHD) but executive function (EF) disorders, as problems with inhibitory control, working memory and reaction time, besides others EFs, may underlie many of the disturbs associated with the disorder. OBJECTIVE: To examine the reaction time in a computerized test in children with ADHD and normal controls. METHOD: Twenty-three boys (aged 9 to 12) with ADHD diagnosis according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, 2000 (DSM-IV) criteria clinical, without comorbidities, Intelligence Quotient (IQ) >89, never treated with stimulant and fifteen normal controls, age matched were investigated during performance on a voluntary attention psychophysical test. RESULTS: Children with ADHD showed reaction time higher than normal controls. CONCLUSION: A slower reaction time occurred in our patients with ADHD. This findings may be related to problems with the attentional system, that could not maintain an adequate capacity of perceptual input processes and/or in motor output processes, to respond consistently during continuous or repetitive activity.

scholarly journals Mental disorders in Australian 4- to 17- year olds: Parent-reported need for help

2017 ◽  
Vol 52 (2) ◽  
pp. 149-162 ◽  
Author(s):  
Sarah E Johnson ◽  
David Lawrence ◽  
Michael Sawyer ◽  
Stephen R Zubrick
Keyword(s):  
Major Depressive Disorder ◽  
Mental Disorders ◽  
Depressive Disorder ◽  
Conduct Disorder ◽  
Unmet Need ◽  
Household Survey ◽  
Conduct Disorders ◽  
Major Depressive ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual

Objective: To describe the extent to which parents report that 4- to 17-year-olds with symptoms meeting Diagnostic and Statistical Manual of Mental Disorders, 4th edition criteria for mental disorders need help, the types of help needed, the extent to which this need is being met and factors associated with a need for help. Method: During 2013–2014, a national household survey of the mental health of Australia’s young people (Young Minds Matter) was conducted, involving 6310 parents (and carers) of 4- to 17-year-olds. The survey identified 12-month mental disorders using the Diagnostic Interview Schedule for Children – Version IV ( n = 870) and asked parents about the need for four types of help – information, medication, counselling and life skills. Results: Parents of 79% of 4- to 17-year-olds with mental disorders reported that their child needed help, and of these, only 35% had their needs fully met. The greatest need for help was for those with major depressive disorder (95%) and conduct disorder (93%). Among these, 39% of those with major depressive disorder but only 19% of those with conduct disorder had their needs fully met. Counselling was the type of help most commonly identified as being needed (68%). In multivariate models, need for counselling was higher when children had autism or an intellectual disability, in blended families, when parents were distressed, and in the most advantaged socioeconomic areas. Conclusions: Many children and adolescents meeting Diagnostic and Statistical Manual of Mental Disorders, 4th edition criteria for mental disorders have a completely unmet need for help, especially those with conduct disorders. Even with mild disorders, lack of clinical assessment represents an important missed opportunity for early intervention and treatment.

Attention Deficit Hyperactivity Disorder

2021 ◽  
pp. 134-147
Author(s):  
Kirstin Painter ◽  
Maria Scannapieco
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Brain Research ◽  
Real Life ◽  
Assessment Tools ◽  
Class Discussion ◽  
Statistical Manual ◽  
Hyperactivity Disorder ◽  
Diagnostic And Statistical Manual ◽  
Prevalence Estimates

Chapter 9 begins with prevalence estimates for attention deficit hyperactivity disorder (ADHD). The symptoms of inattention, hyperactivity-impulsivity, and impulsivity are addressed, followed by descriptions of how these symptoms present in children and adolescents. An overview of the Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria for diagnosing ADHD is presented. The chapter includes a discussion of the causes of ADHD and current research, with a focus on possible linkages between ADHD and biological, genetic, environmental, and nutritional causes and current brain research. Diagnosing youth using DSM criteria along with differentiating ADHD and other disorders is discussed. Common assessment tools used to screen for symptoms of ADHD are presented. Chapter 9 ends with two real-life case studies and questions for class discussion.

scholarly journals Prevalence of Inflammatory Bowel Disease in Pediatric and Adult Populations: Recent Estimates From Large National Databases in the United States, 2007–2016

2019 ◽  
Author(s):  
Yizhou Ye ◽  
Sudhakar Manne ◽  
William R Treem ◽  
Dimitri Bennett
Keyword(s):  
United States ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Fixed Effects ◽  
Adult Population ◽  
The United States ◽  
Adult Age ◽  
The Us ◽  
Inflammatory Bowel ◽  
National Databases

Abstract Background The latest estimate of the prevalence of inflammatory bowel disease (IBD) in the United States was based on 2009 data, which indicates a need for an up-to-date re-estimation. The objectives of this study were to investigate the prevalence of all forms of IBD including ulcerative colitis (UC), Crohn’s disease (CD), and IBD unspecified (IBDU). Methods Pediatric (age 2–17) and adult (age ≥18) IBD patients were identified from 2 large claims databases. For each year between 2007 and 2016, prevalence was calculated per 100,000 population and standardized based on the 2016 national Census. A fixed-effects meta-analytical model was used for overall prevalence. Results The pediatric prevalence of IBD overall increased by 133%, from 33.0/100,000 in 2007 to 77.0/100,000 in 2016. Among children, CD was twice as prevalent as UC (45.9 vs 21.6). Prevalence was higher in boys than girls for all forms of IBD, in contrast to the adult population where the prevalence was higher in women than men. We also found that the 10–17 age subgroup was the major contributor to the rising pediatric IBD prevalence. For adults, the prevalence of IBD overall increased by 123%, from 214.9 in 2007 to 478.4 in 2016. The prevalence rates of UC and CD were similar (181.1 vs 197.7) in 2016. Conclusions Inflammatory bowel disease continues to affect a substantial proportion of the US population. In 2016, 1 in 209 adults and 1 in 1299 children aged 2–17 were affected by IBD. Prevalence of IBD has been increasing compared with previously published 2009 data.

scholarly journals Mental Distress in the United States at the Beginning of the COVID-19 Pandemic

2020 ◽  
Vol 110 (11) ◽  
pp. 1628-1634 ◽  
Author(s):  
Calliope Holingue ◽  
Luther G. Kalb ◽  
Kira E. Riehm ◽  
Daniel Bennett ◽  
Arie Kapteyn ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Odds Ratio ◽  
Mental Distress ◽  
Adult Population ◽  
The United States ◽  
The Us ◽  
Patient Health ◽  
Completion Date ◽  
History Of ◽  
The Impact

Objectives. To assess the impact of the COVID-19 pandemic on mental distress in US adults. Methods. Participants were 5065 adults from the Understanding America Study, a probability-based Internet panel representative of the US adult population. The main exposure was survey completion date (March 10–16, 2020). The outcome was mental distress measured via the 4-item version of the Patient Health Questionnaire. Results. Among states with 50 or more COVID-19 cases as of March 10, each additional day was significantly associated with an 11% increase in the odds of moving up a category of distress (odds ratio = 1.11; 95% confidence interval = 1.01, 1.21; P = .02). Perceptions about the likelihood of getting infected, death from the virus, and steps taken to avoid infecting others were associated with increased mental distress in the model that included all states. Individuals with higher consumption of alcohol or cannabis or with history of depressive symptoms were at significantly higher risk for mental distress. Conclusions. These data suggest that as the COVID-19 pandemic continues, mental distress may continue to increase and should be regularly monitored. Specific populations are at high risk for mental distress, particularly those with preexisting depressive symptoms.

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