Effects of dietary fatty acids on lipogenesis and lipid traits in muscle, adipose tissue and liver of growing rabbits

1998 ◽  
Vol 66 (2) ◽  
pp. 483-489 ◽  
Author(s):  
F. Gondret ◽  
J. Mourot ◽  
F. Lebas ◽  
M. Bonneau
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Polyunsaturated Fatty Acids ◽  
Lipid Content ◽  
Saturated Fatty Acids ◽  
Coconut Oil ◽  
Basal Diet ◽  
Dietary Fatty Acids ◽  
Medium Chain ◽  
Perirenal Fat

AbstractThe effects of fat source on lipogenesis and lipid traits of longissimus muscle, liver and perirenal adipose tissue, were studied in 48 New Zealand White rabbits, slaughtered at 11 or 15 weeks of age. Rabbits were offered diets with 20 g added fat per kg, containing either medium-chain (COC: coconut oil), saturated and monounsaturated (PAL: palm oil) or polyunsaturated (SUN: sunflower oil) fatty acids as major components. Diets did not affect growth performance, dressing proportion and tissue weights. Intramuscular lipid content was lower for COC than for SUN and PAL (e.g. 10 v. 13 and 12 glkg, at 11 weeks, respectively, P < 0·05), whereas lipid content was unaffected by diet in liver and perirenal fat. In muscle, the fat source did not influence the activities of acetyl-CoA-carboxylase (CBX), malic enzyme (ME) and glucose-6-phosphodehydrogenase (G6PDH). In liver, activities ofGSPDH and ME were depressed from the SUN diet, as compared with the COC or PAL diets. The diet-induced variations in enzyme activities in perirenal fat were lower than in the liver and were not significant. Medium-chain fatty acids were found only in tissue lipids of animals given COC. The ratio of polyunsaturated to saturated fatty acids decreased in the order SUN > PAL > COC in muscle and perirenal fat. Thus, polyunsaturated fatty acids exert an inhibition of G6PDH and ME activities specifically in liver. Compared with COC, the addition of SUN to the basal diet increased total lipids and polyunsaturated fatty acids contents in the longissimus lumborum muscle, which might improve the organoleptic and dietetic qualities of rabbit meat.

scholarly journals Effect of storage on fatty acid profile of butter from cows fed whole or ground flaxseed with or without monensin

2010 ◽  
Vol 39 (10) ◽  
pp. 2297-2303 ◽  
Author(s):  
Daniele Cristina da Silva-Kazama ◽  
Geraldo Tadeu dos Santos ◽  
Paula Toshimi Matumoto Pintro ◽  
Jesuí Vergílio Visentainer ◽  
Ricardo Kazama ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Fatty Acid Profile ◽  
Saturated Fatty Acids ◽  
Relative Percentage ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Ground Flaxseed ◽  
Chain Fatty Acids

Eight Holstein cows with body weight 570 ± 43 kg and 60 ± 20 lactation days were distributed in a double Latin square design with four 21-day periods to determine the effects of feeding ground or whole flaxseed with or without monensin supplementation (0.02% on a dry matter basis) on fatty acid profile of butter stored for 15 and 45 days. Ground flaxseed supply, in comparison to whole flaxseed, reduced relative percentages of 16:0, cis7-16:1, 17:0, and cis10-17:1 but it increased those of cis9,trans11-18:2, cis3-18:3, and omega 3 fatty acids in butter fat, reducing relative percentage of medium-chain fatty acids and increasing the content of polyunsaturated fatty acids. Supplementation with monensin increased relative percentages of cis9,trans11-18:2 and tended to increase relative percentage of 17:0 and decrease that of saturated fatty acids in butter. Butter from cows fed diet with monensin presented lower relative percentages of cis 6-20:4. Relative percentages of cis 9-16:1, cis10-17:1, 18:0, trans11-18:1, cis9-18:1, cis3-18:3, cis6-20:4 in butter stored for 15 days were higher than those stored for 45 days and the relative percentages of cis3-20:5 tended to decrease with the increase of storage period. As a result, relative percentages of saturated fatty acids and medium-chain fatty acids increased with storage time, while those of monounsaturated and long-chain fatty acids decreased. Butter enriched with polyunsaturated fatty acids may have a shorter shelf life due to the negative effect of storage on fatty acid profile which may cause oxidation and rancidity.

scholarly journals The Production of Biofuels from Coconut Oil Using Microwave

2015 ◽  
Vol 9 (7) ◽  
pp. 93 ◽  
Author(s):  
A Suryanto ◽  
Suprapto Suprapto ◽  
Mahfud Mahfud
Keyword(s):  
Fatty Acids ◽  
Reaction Time ◽  
Lauric Acid ◽  
Myristic Acid ◽  
Saturated Fatty Acids ◽  
Electrical Power ◽  
Coconut Oil ◽  
Raw Material ◽  
Medium Chain ◽  
Acid Reaction

Biofuels including biodiesel, an alternative fuel, is renewable, environmentally friendly, non-toxic and lowemission energy. The raw material used in this work was coconut oil, which contained saturated fatty acids about90% with medium chain (C8-C12), especially lauric acid and myristic acid. Reaction was conducted in batchreactor assisted by microwave. The purpose of this research was to study the effect of power and NaOH catalystin transesterification enhanced by microwave and to obtain a biofuels (biodiesel and biokerosene) derived fromcoconut oil. The reaction was performed by mixing oil and methanol with mole ratio of 1:6, catalystconcentration of 1% w/w with setting electrical power at 100, 264, 400, 600 and 800 W. The reaction time wasconditioned at of 2.5, 5, 7.5, 10 and 15 min. The results showed that microwave could accelerate thetransesterification process to produce biodiesel using NaOH catalyst. The highest yield of biodiesel was 97.76 %,or 99.05 % conversion at 5 min reaction, meanwhile biokerosene was 48% after distillation.

scholarly journals Dietary and Pharmacological Fatty Acids and Cardiovascular Health

2019 ◽  
Vol 105 (4) ◽  
pp. 1030-1045 ◽  
Author(s):  
Huaizhu Wu ◽  
Lu Xu ◽  
Christie M Ballantyne
Keyword(s):  
Fatty Acids ◽  
Clinical Trials ◽  
Polyunsaturated Fatty Acids ◽  
Cardiovascular Health ◽  
Evidence Synthesis ◽  
Saturated Fatty Acids ◽  
Saturated Fat ◽  
Dietary Fatty Acids ◽  
Atherosclerotic Cardiovascular Disease ◽  
Omega 3

Abstract Context The effects of dietary intake of different fatty acids and pharmacological use of fatty acids, specifically long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFAs), on cardiovascular health and atherosclerotic cardiovascular disease (ASCVD) prevention have been examined in a large number of observational studies and clinical trials. This review summarizes recent data and discusses potential mechanisms. Evidence acquisition The review is based on the authors’ knowledge of the field supplemented by a PubMed search using the terms seafood, fish oil, saturated fatty acids, omega-3 fatty acids, eicosapentaenoic acid, docosahexaenoic acid, polyunsaturated fatty acids, monounsaturated fatty acids, and ASCVD. Evidence synthesis We mainly discuss the recent clinical trials that examine the effects of different types of dietary fatty acids and pharmacological use of n-3 PUFA products on ASCVD prevention and the potential mechanisms. Conclusions While replacement of dietary saturated fat with unsaturated fat, polyunsaturated fat in particular, or intake of LC n-3 PUFA–rich seafood has generally shown benefit for ASCVD prevention and is recommended for cardiovascular benefits, data on effects of n-3 PUFA products on ASCVD health are inconsistent. However, recent clinical trials support benefits of prescription EPA in ASCVD prevention. n-3 PUFAs may contribute to ASCVD prevention through multiple mechanisms, including lowering plasma triglyceride levels, anti-inflammatory effects, antithrombotic effects, and effects on endothelial function.

Composition and textural properties of Mozzarella cheese naturally-enriched in polyunsaturated fatty acids

2013 ◽  
Vol 80 (3) ◽  
pp. 276-282 ◽  
Author(s):  
Mariangela Caroprese ◽  
Agostino Sevi ◽  
Rosaria Marino ◽  
Antonella Santillo ◽  
Alessandra Tateo ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Chemical Composition ◽  
Polyunsaturated Fatty Acids ◽  
Fish Oil ◽  
Saturated Fatty Acids ◽  
Textural Properties ◽  
Basal Diet ◽  
Monounsaturated Fatty Acids ◽  
Mozzarella Cheese ◽  
Bulk Milk

The effects of adding flaxseed or fish oil to the diet of dairy cows on the chemical and physical profile of Mozzarella cheese production were studied. The experiment involved 24 Friesian cows, divided into 3 groups accordingly fat supplementation: basal diet (CT), diet supplemented with flaxseed (FS) or fish oil (FO). Mozzarella cheeses were manufactured from bulk milk of each group. Bulk milk was analysed for chemical composition and renneting parameters. Mozzarella cheeses were analysed for chemical composition, fatty acid profile, and textural properties. Results suggest that Mozzarella cheese from cows receiving flaxseed supplementation showed a decrease in saturated fatty acids (SFA), an increase in monounsaturated fatty acids (MUFA), and in polyunsaturated fatty acids (PUFA) compared with control Mozzarella cheese. The increased dietary intake of C18:3 in flaxseed supplemented cows resulted in increased levels of trans-11 C18:1, and of CLA cis-9 trans-11 C18:2, and in low Atherogenic and Trombogenic Indexes. FO Mozzarella cheese showed compositional and textural properties quite similar to CT Mozzarella cheese; however, increased levels of n-3 polyunsaturated fatty acids in FO Mozzarella were found.

scholarly journals Analysis of Fatty Acids in Virgin Coconut Oil Frying at Various Temperatures

2021 ◽  
Vol 10 (1) ◽  
pp. 104
Author(s):  
Dewa Ayu Ika Pramitha ◽  
I Wayan Karta
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Acid Content ◽  
Saturated Fatty Acids ◽  
Fatty Acid Content ◽  
Medium Chain Triglyceride ◽  
Coconut Oil ◽  
Virgin Coconut Oil ◽  
Medium Chain ◽  
Cooking Oil

Fatty acid content from virgin coconut oil (VCO) is a medium-chain triglyceride (MCT) group. MCT is stable at very low and high temperatures, and the color does not turn black due to the addition of heat so that it can be developed into beneficial cooking oil for health. Therefore, a study was conducted on the content of fatty acids in VCO after being heated at temperatures of 150, 200, and 250°C for 60 minutes. Analysis of fatty acid content in control VCO(T0), VCO with heating temperatures of 150oC(T1), 200oC(T2), and 250oC(T3) was performed with GCMS QP-2010 Ultra.The results showed that there were differences in levels and types of fatty acids in VCO by treating T0, T1, T2, and T3. At these three temperatures still produce medium-chain saturated fatty acids and trans fatty acids are not produced, so that VCO can be utilized as cooking oil that has better stability and benefits for health.

scholarly journals Strategies for altering population intakes of fats and fatty acids

1999 ◽  
Vol 58 (1) ◽  
pp. 189-191 ◽  
Author(s):  
M. J. Gibney
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Saturated Fatty Acids ◽  
Dietary Guidelines ◽  
Dietary Fatty Acids ◽  
Dietary Intakes ◽  
The Usa ◽  
Total Fat ◽  
The Uk

Quantitative dietary guidelines for fats were first issued in 1977 in the USA and these guidelines have changed little since then. In the UK only 14 % of the population achieve the dietary goal for fat (33 % energy) and only 3 % achieve the target (10 % energy) from saturated fatty acids. Analysis of the Dietary and Nutritional Survey of British Adults reveals that across quartiles of decreasing total fat intake, the actual fatty acid composition of this fat does not alter; i.e. when total fat is lowered, all fatty acid categories are equally lowered. This arises because 85 % of total fat and of each of the categories of fatty acids are provided by just five foods (milk, meat, cereals, spreads and vegetables). When total fat in the UK is lowered, the intake of polyunsaturated fatty acids is lowered. The problem is that if the intake of polyunsaturated fatty acids falls below a threshold of about 5 % energy, the cholesterol-raising properties of certain saturated fatty acids, e.g. myristic acid, are greatly augmented. In order to alter the balance of dietary fatty acids, more data are needed on food choices of those in the population achieving particular targets. These targets cannot be based on existing dietary goals, since so few people attain them. A new set of‘interim attainable dietary guidelines’, based on prevailing dietary intakes, must be the basis for establishing sensible food-based dietary guidelines.

scholarly journals Dietary Fatty Acids, Macronutrient Substitutions, Food Sources and Incidence of Coronary Heart Disease: Findings From the EPIC‐CVD Case‐Cohort Study Across Nine European Countries

2021 ◽  
Author(s):  
Marinka Steur ◽  
Laura Johnson ◽  
Stephen J. Sharp ◽  
Fumiaki Imamura ◽  
Ivonne Sluijs ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Coronary Heart Disease ◽  
Cohort Study ◽  
Heart Disease ◽  
Polyunsaturated Fatty Acids ◽  
Energy Intake ◽  
Saturated Fatty Acids ◽  
Monounsaturated Fatty Acids ◽  
Dietary Fatty Acids ◽  
Food Sources

Background There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids [SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically, the relevance of food sources of SFAs to CHD associations is uncertain. Methods and Results We conducted a case‐cohort study involving 10 529 incident CHD cases and a random subcohort of 16 730 adults selected from a cohort of 385 747 participants in 9 countries of the EPIC (European Prospective Investigation into Cancer and Nutrition) study. We estimated multivariable adjusted country‐specific hazard ratios (HRs) and 95% CIs per 5% of energy intake from dietary fatty acids, with and without isocaloric macronutrient substitutions, using Prentice‐weighted Cox regression models and pooled results using random‐effects meta‐analysis. We found no evidence for associations of the consumption of total or fatty acid classes with CHD, regardless of macronutrient substitutions. In analyses considering food sources, CHD incidence was lower per 1% higher energy intake of SFAs from yogurt (HR, 0.93 [95% CI, 0.88–0.99]), cheese (HR, 0.98 [95% CI, 0.96–1.00]), and fish (HR, 0.87 [95% CI, 0.75–1.00]), but higher for SFAs from red meat (HR, 1.07 [95% CI, 1.02–1.12]) and butter (HR, 1.02 [95% CI, 1.00–1.04]). Conclusions This observational study found no strong associations of total fatty acids, SFAs, monounsaturated fatty acids, and polyunsaturated fatty acids, with incident CHD. By contrast, we found associations of SFAs with CHD in opposite directions dependent on the food source. These findings should be further confirmed, but support public health recommendations to consider food sources alongside the macronutrients they contain, and suggest the importance of the overall food matrix.

Effect of dietary n-3/n-6 ratio on fatty acid composition of liver, meat and perirenal fat in rabbits

1999 ◽  
Vol 68 (4) ◽  
pp. 647-654 ◽  
Author(s):  
M. Bernardini ◽  
A. Dal Bosco ◽  
C. Castellini
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Fish Oil ◽  
Fatty Acid Profile ◽  
Unsaturated Fatty Acids ◽  
Meat Products ◽  
Dietary Fatty Acids ◽  
Longissimus Lumborum ◽  
Perirenal Fat

AbstractThe metabolic pathways of dietary fatty acids were studied in rabbits by analysing the fatty acid profile of different tissues (liver, perirenal fat,longissimus lumborummuscle). Four groups of 24 hybrid males each were assigned to four semi-purified diets, varying in the source oflipids which differed in n-3/n-6 ratios: 180 g/kg sunflower (S), 80 g/kg flaxseed + 90 g/kg sunflower (SF), 160 g/kg flaxseed (F) and 60 g/kg fish oil (FI). The liver showed a very important rôle in fatty acid syntheses and was the tissue richest in long-chain (≥20 C) polyunsaturated fatty acids (LCP) of n-3 and n-6 series. The S diet gave the highest mono-unsaturated fatty acids and n-6 LCP (respectively, 201·9 and 384·9 g/kg,P< 0·01) also showing a clear antagonism v. n-3 LCP; the FI diet determined the highest enrichment of n-3 LCP (179·5 g/kg,P< 0·01). a-linolenic acid was efficiently converted into n-3 LCP mainly when п-ЗІп-6 ratio was high (Σn-3/С20: 4n-6: 2·74 and 3.61,P< 0·01 in flaxseed and fish-oil diet, respectively). The same trend occurred in the muscle but in a less consistent way. The adipose tissue more closely reflected the composition of the dietary fatty acids, showing variations mainly concerning polyunsaturated fatty acids (S diet), and LCP n-3 (FI diet: 44·9 g/kg,P< 0·01). Results showed the possibility of modifying the fatty acid profile of rabbit meat by dietary means and that the n-3/n-6 ratio of the food is crucial in regulating the relative presence of LCP n-3 or n-6 in meat products.

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