scholarly journals Vitamin D deficiency among healthy children in developing countries: an epidemic being recognized

2015 ◽  
Vol 19 (8) ◽  
pp. 1526-1527 ◽  
Author(s):  
Suresh Kumar Angurana ◽  
Vikas Mahajan
Keyword(s):  
Vitamin D ◽  
Developing Countries ◽  
Vitamin D Deficiency ◽  
Healthy Children

scholarly journals Vitamin D i pokazateli kal'tsiy-fosfornogo obmenau detey, prozhivayushchikh v sredney polose Rossii, v periodmaksimal'noy insolyatsii

2010 ◽  
Vol 13 (2) ◽  
pp. 2-6 ◽  
Author(s):  
A. V. Vitebskaya ◽  
G. E. Smirnova ◽  
A. V. Il'in
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Central Area ◽  
Hypovitaminosis D ◽  
Vitamin D Insufficiency ◽  
Winter Period ◽  
Published Data ◽  
Healthy Children ◽  
Hydroxyvitamin D ◽  
Oncological Diseases

Vitamin D deficiency is associated with rickets in children and osteomalation in adults. Published data support the role of vitamin D insufficiency in development of autoimmune, cardiovascular and oncological diseases. The most precise method to diagnose vitamin D insufficiency is measuring of 25-hydroxyvitamin D (25(OH)-D). We studded the levels of vitamin D and calcium-phosphate turnover parameters during the period of maximal insolation in 140 healthy children and adolescents permanently living in the central area of Russia. Vitamin D insufficiency (25(OH)-D < 20 ng/ml) was detected in 38,6%; in 2,9% of them severe vitamin D deficiency was diagnosed (25(OH)-D < 8 ng/ml). The results correlate with data on hypovitaminosis D prevalence in countries with the same geographical latitude. To clarify the real size of required prophylaxis we need investigation of the same parameters in winter period while minimal insolation.

scholarly journals Possible Health Implications and Low Vitamin D Status during Childhood and Adolescence: An Updated Mini Review

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Dimitrios Papandreou ◽  
Pavlos Malindretos ◽  
Zacharoula Karabouta ◽  
Israel Rousso
Keyword(s):  
Cardiovascular Disease ◽  
Vitamin D ◽  
Developing Countries ◽  
Life Span ◽  
Vitamin D Deficiency ◽  
Chronic Diseases ◽  
Adult Life ◽  
Childhood And Adolescence ◽  
Vitamin D Status ◽  
Calcium Insufficiency

Vitamin D deficiency is common in the developing countries and exists in both childhood and adult life. The great importance of Vitamin D is the moderation of calcium (Ca) and phosphorus (P) homeostasis as well as the absorption of Ca. While insufficiency of vitamin D is a significant contributing factor to risk of rickets in childhood, it is possible that a more marginal deficiency of vitamin D during life span contribute to osteoporosis as well as potentially to the development and various other chronic diseases such as cardiovascular disease, cancer and diabetes. This paper reviews the metabolism, epidemiology, and treatment of vitamin D and calcium insufficiency as well as its relation to various diseases during childhood and adolescence.

Prevalence of vitamin D deficiency in apparently healthy children in north India

2014 ◽  
Vol 0 (0) ◽  
Author(s):  
Suresh Kumar Angurana ◽  
Renu Suthar Angurana ◽  
Gagan Mahajan ◽  
Neeraj Kumar ◽  
Vikas Mahajan
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
North India ◽  
Healthy Children ◽  
Apparently Healthy

High prevalence of vitamin D deficiency in type 1 diabetes mellitus and healthy children

2008 ◽  
Vol 46 (3) ◽  
pp. 183-189 ◽  
Author(s):  
Abdulbari Bener ◽  
Amer Alsaied ◽  
Mariam Al-Ali ◽  
Aisha Al-Kubaisi ◽  
Basma Basha ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Vitamin D ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Vitamin D Deficiency ◽  
Healthy Children ◽  
High Prevalence

scholarly journals Low Level of Vitamin D is Correlated with High C-Reactive Protein (CRP) and Disease Activity in Indonesian Juvenile Idiopathic Arthritis (JIA) Patients

2020 ◽  
Vol 12 (2) ◽  
pp. 149-56
Author(s):  
Desy Wulandari ◽  
Wisnu Barlianto ◽  
Tita Luthfia Sari
Keyword(s):  
Vitamin D ◽  
Juvenile Idiopathic Arthritis ◽  
Serum Level ◽  
Disease Activity ◽  
Vitamin D Deficiency ◽  
Control Group ◽  
Healthy Children ◽  
C Reactive Protein ◽  
Low Level ◽  
Reactive Protein

BACKGROUND: Vitamin D plays essential role in the regulation of inflammation, such as in pathogenesis of Juvenile Idiopathic Arthritis (JIA). Vitamin D deficiency has been reported among JIA patients, but there were conflicting results regarding the correlation with disease activity. This study aimed to assess vitamin D serum level and its correlation with C-Reactive Protein (CRP) and disease activity in JIA patients.METHODS: Children who were diagnosed with JIA according to International League of Associations for Rheumatology (ILAR) criterias were enrolled as JIA group subjects, while age and sex-matched healthy children were enrolled as the control group subjects. Vitamin D and CRP serum level were measured. Disease activity of JIA patients was calculated by Juvenile Arthritis Disease ActivityScore-27 (JADAS-27).RESULTS: Vitamin D serum level was lower in the JIA group compared to the healthy control group (p=0.000). Among 26 JIA patients, 61.5% were deficient, 30.8% were insufficient, and 7.7% had normal vitamin D. No significant different in CRP level between vitamin D group (p=0.441), but there was significant different in JADAS-27 (p=0.001). The mean of CRP and JADAS-27 were found highest in vitamin D deficiency group. Vitamin D serum level was negatively correlate with CRP (p=0.021, r=-0.452) and JADAS-27 (p=0.001 r=-0.595).CONCLUSION: Low level of vitamin D in JIA patients was inversely related to higher CRP and disease activity,suggesting that vitamin D supplementation could be havepotential role in JIA treatment.KEYWORDS: vitamin D, CRP, disease activity,JADAS-27, JIA

scholarly journals Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status

2021 ◽  
Vol 14 ◽  
pp. 117863882110187
Author(s):  
Hedyeh Saneifard ◽  
Marjan Shakiba ◽  
Ali Sheikhy ◽  
Leila Baniadam ◽  
Fatemeh Abdollah Gorji ◽  
...  
Keyword(s):  
Vitamin D ◽  
Children And Adolescents ◽  
Vitamin D Deficiency ◽  
Tanner Stage ◽  
Additional Risk Factor ◽  
Healthy Children ◽  
Vitamin D Status ◽  
Obese Children ◽  
Increased Risk ◽  
Vitamin D Levels

Background: Vitamin D deficiency is common among children and adolescents and can be affected by several factors such as puberty and obesity. Objective: The aim of this study was to evaluate vitamin D status in children and adolescents and to analyse the influence of puberty and obesity on its level. Method: A cross-sectional study was carried-out, in which clinical and biochemical data were gathered from 384 healthy children and adolescents between May 2019 to May 2020. Results: 220 females and 164 males were enrolled (aged 7-16 years; mean ± SD: 11 ± 2.5). Vitamin D deficiency was found in 49% of the total cases and was significantly more prevalent in females than males (33.1% in female; 15.9% in male, P < .001). Mean vitamin D level was lower in obese children compared with non-obese ( P < .001). Non-obese group had significantly higher levels of vitamin D in Tanner stage IV of puberty than obese individuals (20.1 ± 17.0 vs 5.4 ± 2.0) ( P = .03). Vitamin D levels were significantly lower in females than males only in Tanner stage II (12.3 ± 9.0 vs 19.6 ± 16.6) ( P = .005). The lowest level of Vitamin D was in Tanner stage Ⅳ-Ⅴ in boys and in Tanner stage Ⅱ-Ⅲ in girls ( P < .001). Conclusion: Puberty is an additional risk factor for vitamin D deficiency especially in girls and obese children. This increased risk, together with the fact that most important time for building a proper skeleton is during childhood and adolescent, makes it essential to monitor vitamin D in these age groups.

scholarly journals Correlation between vitamin D levels and bone metabolism in children with cow’s milk allergy

2022 ◽  
Vol 50 (1) ◽  
pp. 030006052110660
Author(s):  
Di Che ◽  
Li Yu ◽  
Yong Guo ◽  
Hai-jin Ke ◽  
Cui Liu ◽  
...  
Keyword(s):  
Vitamin D ◽  
Risk Factor ◽  
Bone Metabolism ◽  
Vitamin D Deficiency ◽  
Cow’S Milk ◽  
Control Group ◽  
Healthy Children ◽  
Serum Calcitonin ◽  
Cow's Milk ◽  
Vitamin D Levels

Objective Research is limited regarding biochemical markers of bone metabolism among children with cow’s milk protein allergy (CMPA). We aimed to determine differences in vitamin D and bone metabolism markers between infants with CMPA and healthy infants and explore relationships between these in a cross-sectional study. Methods In total, we included 41 children diagnosed with CMPA and under systematic medical and nutritional care at our center, and 50 healthy children as a control group. We reviewed demographic and clinical characteristics and measured serum biomarkers. Results We found that serum 25-hydroxyvitamin D (25(OH)D) levels among infants in the CMPA group were significantly lower than those in the control group, and levels of bone-specific alkaline phosphatase (BALP), serum phosphorus, and serum calcitonin were reduced. Pearson correlation analysis showed that serum 25(OH)D concentrations in the CMPA group were negatively correlated with parathyroid hormone but not significantly correlated with calcitonin and BALP. Logistic regression showed that CMPA was a risk factor for vitamin D deficiency. Conclusions Our study indicated that CMPA was associated with disturbances in bone metabolism. Levels of vitamin D in children with CMPA were lower than those in healthy children. CMPA was a risk factor for vitamin D deficiency.

scholarly journals Associations of Maternal Vitamin D Deficiency with Pregnancy and Neonatal Complications in Developing Countries: A Systematic Review

Nutrients ◽  
2018 ◽  
Vol 10 (5) ◽  
pp. 640 ◽  
Author(s):  
Paige van der Pligt ◽  
Jane Willcox ◽  
Ewa Szymlek-Gay ◽  
Emily Murray ◽  
Anthony Worsley ◽  
...  
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Developing Countries ◽  
Vitamin D Deficiency ◽  
Maternal Vitamin ◽  
Neonatal Complications

scholarly journals Association of Vitamin D Deficiency with Acute Lower Respiratory Infection in Toddlers

2016 ◽  
Vol 36 (1) ◽  
pp. 14-16 ◽  
Author(s):  
Gursharan Singh Narang ◽  
Sunita Arora ◽  
Sahiba Kukreja ◽  
Dr Shifali
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Univariate Analysis ◽  
Significant Risk ◽  
World Health ◽  
Control Group ◽  
Acute Lower Respiratory Infection ◽  
Healthy Children ◽  
Severe Vitamin

Introduction: Pneumonia remains a significant health problem in India with significant morbidity and mortality. Objectives of this study were to identifying an effective nutritional agent that reduces the need for antibiotics, duration of pneumonia and length of hospitalization would be highly cost-beneficial.Material and Methods: This was a hospital-based case-control study: A total of 100 children including 50 cases and 50 controls, aged 2–60 months, were enrolled. Case definition of severe ALRI as given by the World Health Organization was used for cases. Controls were healthy children attending outpatients’ service for immunization or admitted for minor ailments other than ALRTI.Results: Mean 25(OH)D concentrations in children of the study group were lower than those of the control group (20.431 ng/mL vs. 27.67 ng/mL; p = 0.035). Factors significantly associated with decreased risk of ALRTI in univariate analysis were: exclusive breastfeeding in the first 6 months (cases 13/50 (26%), controls 42/50 (84%); p=0.000); adequate exposure to sunlight (cases 14/50 (28%), controls 42/50 (84%); P=0.000); and serum 25OHD3 <20 ng/ml (cases 28/50 (56%), controls 0/50 (0%); p=.000). Multivariate logistic model indicated that severe vitamin D deficiency (OR=NA), exclusive breast feeding (OR=.174); 95% CI (.061- .521; p=.002) and adequate sunlight exposure (OR=.179) ;95%CI (.062-.519); p=.002) were significant independent predictive risk factors for ALRTI among the children between 2 months – 5 years of age (all p<0.05).Conclusion: Severe vitamin D deficiency (<20ng/ml), nonexclusive breastfeeding in the first six months of life, inadequate sun exposure were significant risk factors for ALRTI in Indian children.J Nepal Paediatr Soc 2016;36(1):14-18

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