Lutein: Separation, Antioxidant Activity, and Potential Health Benefits

Author(s):  
Rong Tsao ◽  
Mingchen Wang ◽  
Zeyuan Deng
2019 ◽  
Vol 7 ◽  
Author(s):  
Adriano Costa De Camargo ◽  
Renan da Silva Lima

Phenolic compounds possess a myriad of health benefits, thus making them potential ingredients for the procurement of food supplements. Anvisa, Brazil’s national regulatory body, has recently revised the regulation on food supplements and only a few phenolic compounds (chlorogenic acid, rutin, proanthocyanidins, and tocopherols) have been mentioned. Despite several scientific evidences on the bioactivity of phenolics, especially concerning their antioxidant activity, Anvisa does not authorize any claims for supplements containing these compounds, except for tocopherols, which was mentioned as “vitamin E”. The upper limit doses allowed for the phenolics appear to be lower than what the literature suggests as necessary to achieve potential health benefits and might be prohibitive for supplements available in the international market. Moreover, Brazilian sources of phenolic compounds are not listed in the Normative Instruction (NI) as authorized ingredients for supplements. The Brazilian NI on food supplements has moved forward, but it is still limited.


Author(s):  
Lalithadevi B ◽  
Muthiah Ns ◽  
Satya Narayana Murty K

Objective: The objective of the present study is to evaluate the antioxidant effect of conjugated linoleic acid (CLA). CLA is a collective term for a group of positional and geometric isomers of linoleic acid with conjugated double bond system. CLA is found in milk products and ruminant meat. CLA has been proved to be having many health benefits, one of them one being antioxidant effect.Methods: Various methods are used to find out the antioxidant effect of CLA. They are 1,1- diphenyl-2-picrylhydrazyl free radical scavenging assay, hydroxy radical scavenging assay, nitrous oxide radical scavenging assay, reducing power method, and phosphomolybdenum antioxidant assay. All these methods were done to test the antioxidant activity of CLA.Results: Standards error of mean calculated for all the tests. Statistical analysis done using one-way analysis of variance between the groups and SPSS software version 20 is used. p<0.05 is considered statistically significant. All the tests are statistically significant.Conclusion: As p values for all the tests came significant, and it was concluded that CLA has got antioxidant property. CLA could protect membranes composed of 1-palmitoyl 2-linoleoyl phosphatidylcholine from oxidative modification under conditions of metal ion-dependent or -independent oxidative stress. Finally, it was concluded that CLA has got potential health benefits such as weight reduction, antiaging, and antioxidative properties.


2021 ◽  
Vol 45 (2) ◽  
Author(s):  
Ademola Adetokunbo Oyagbemi ◽  
Temitayo Olabisi Ajibade ◽  
Yapo Guillaume Aboua ◽  
Idayat Titilayo Gbadamosi ◽  
Aduragbenro Deborah A. Adedapo ◽  
...  

2021 ◽  
Vol 71 (1) ◽  
Author(s):  
Trishala Gopikrishna ◽  
Harini Keerthana Suresh Kumar ◽  
Kumar Perumal ◽  
Elavarashi Elangovan

Abstract Purpose Fermented soybean foods (FSF) is popularly consumed in the South-East Asian countries. Bacillus species, a predominant microorganism present in these foods, have demonstrated beneficial and deleterious impacts on human health. These microorganisms produce bioactive compounds during fermentation that have beneficial impacts in improving human health. However, the health risks associated with FSF, food pathogens, biogenic amines (BAs) production, and late-onset anaphylaxis, remain a concern. The purpose of this review is to present an in-depth analysis of positive and negative impacts as a result of consumption of FSF along with the measures to alleviate health risks for human consumption. Methods This review was composed by scrutinizing contemporary literature of peer-reviewed publications related to Bacillus and FSF. Based on the results from academic journals, this review paper was categorized into FSF, role of Bacillus species in these foods, process of fermentation, beneficial, and adverse influence of these foods along with methods to improve food safety. Special emphasis was given to the potential benefits of bioactive compounds released during fermentation of soybean by Bacillus species. Results The nutritional and functional properties of FSF are well-appreciated, due to the release of peptides and mucilage, which have shown health benefits: in managing cardiac disease, gastric disease, cancer, allergies, hepatic disease, obesity, immune disorders, and especially microbial infections due to the presence of probiotic property, which is a potential alternative to antibiotics. Efficient interventions were established to mitigate pitfalls like the techniques to reduce BAs and food pathogens and by using a defined starter culture to improve the safety and quality of these foods. Conclusion Despite some of the detrimental effects produced by these foods, potential health benefits have been observed. Therefore, soybean foods fermented by Bacillus can be a promising food by integrating effective measures for maintaining safety and quality for human consumption. Further, in vivo analysis on the activity and dietary interventions of bioactive compounds among animal models and human volunteers are yet to be achieved which is essential to commercialize them for safe consumption by humans, especially immunocompromised patients.


2020 ◽  
Vol 5 (1) ◽  
pp. 857-870
Author(s):  
Fernando Gonçalves ◽  
João Carlos Gonçalves ◽  
Ana Cristina Ferrão ◽  
Paula Correia ◽  
Raquel P. F. Guiné

AbstractRecently, edible flowers (EF) have aroused increased interest because of their aesthetic properties as well as potential health benefits related to the occurrence of some bioactive compounds. Therefore, the aim of this work was to evaluate the total phenolics, anthocyanins, flavonoids, and antioxidant activity (AOA) (following DPPH and ABTS methods) in eleven EF. The samples were subjected to three successive extraction steps using methanol, and these extracts were then analysed for the aforementioned properties using spectrophotometric methods. The obtained extracts were used for the quantification of phenolic composition and AOA. The results indicated that, among the flowers analysed in this study, red rose, pink rose, and red carnation possessed the highest total phenolic contents (27.53, 23.30, and 18.17 mg g−1 gallic acid equivalents, respectively), total anthocyanins (3.07, 1.97, and 4.47 mg g−1 catechin equivalents [CE], respectively), and AOA (12.07, 15.77, and 12.93 mg g−1 TE, respectively, as given by the DPPH method or 8.23, 9.27 and 8.00 mg g−1 TE, respectively, as given by the ABTS method). The flowers with highest flavonoids contents were red carnation, Mexican marigold, and pink rose (17.50, 16.90, and 16.57 mg g−1 CE, respectively). Cluster analysis grouped the analysed flowers into two groups, those richest in phenolics with AOA and those not so rich. Finally, some important correlations were observed between the total phenolics and the AOA. In conclusion, these flowers could represent a potential source of natural compounds with antioxidant capacity.


2021 ◽  
Vol 8 (1) ◽  
Author(s):  
James Louis-Jean ◽  
Debbie Sanon ◽  
Kevin Louis-Jean ◽  
Nicole Sanon ◽  
Ruthonce Stvil Louis-Jean ◽  
...  

AbstractThe biochemical process of fermentation (zymology) is widely practical for foods and beverages. This metabolic process involves microorganisms (bacteria) and their enzymes in the preparation and preservation of foods. Many studies have shown that fermented foods and beverages have various documented health benefits to humans, such as being high in vitamin b, and, among other benefits, having atherogenic and anticarcinogenic properties. This communication discusses the significance of fermentation in Haitian cuisine by focusing on pikliz—a spicy fermented meal garnishment that is widely popular among Haitian dishes. This analysis provides relevant information on Haitian cuisine while examining the underlying mechanisms, compositions, properties, nutritional values, and potential health benefits of pikliz. This spicy meal garnishment represents the regional, ethnic, and national identity of Haitians living in Haiti and abroad.


2016 ◽  
Vol 213 ◽  
pp. 850-859 ◽  
Author(s):  
Jing Meng ◽  
Junfeng Liu ◽  
Songmiao Fan ◽  
Chuyun Kang ◽  
Kan Yi ◽  
...  

2021 ◽  
Vol 28 ◽  
Author(s):  
Karim Seif El-Dahan ◽  
Dima Machtoub ◽  
Gaelle Massoud ◽  
Suzanne A. Nasser ◽  
Bassam Hamam ◽  
...  

: Cannabis is the most widely trafficked and abused illicit drug due to its calming psychoactive properties. It has been increasingly recognized as having potential health benefits and relatively less adverse health effects as compared to other illicit drugs; however, growing evidence clearly indicates that cannabis is associated with considerable adverse cardiovascular events. Recent studies have linked cannabis use to myocardial infarction (MI); yet, very little is known about the underlying mechanisms. A MI is a cardiovascular disease characterized by a mismatch in the oxygen supply and demand of the heart, resulting in ischemia and subsequent necrosis of the myocardium. Since cannabis is increasingly being considered a risk factor for MI, there is a growing need for better appreciating its potential health benefits and consequences. Here, we discuss the cellular mechanisms of cannabis that lead to an increased risk of MI. We provide a thorough and critical analysis of cannabinoids’ actions, which include modulation of adipocyte biology, regional fat distribution, and atherosclerosis, as well as precipitation of hemodynamic stressors relevant in the setting of a MI. By critically dissecting the modulation of signaling pathways in multiple cell types, this paper highlights the mechanisms through which cannabis may trigger life-threatening cardiovascular events. This then provides a framework for future pharmacological studies which can identify targets or develop drugs that modulate cannabis’ effects on the cardiovascular system as well as other organ systems. Cannabis’ impact on the autonomic outflow, vascular smooth muscle cells, myocardium, cortisol levels and other hemodynamic changes are also mechanistically reviewed.


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