scholarly journals Mapping the Surface Microbiome and Metabolome of Brown Seaweed Fucus vesiculosus by Amplicon Sequencing, Integrated Metabolomics and Imaging Techniques

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Delphine Parrot ◽  
Martina Blümel ◽  
Caroline Utermann ◽  
Giuseppina Chianese ◽  
Stefan Krause ◽  
...  
Keyword(s):  
Imaging Techniques ◽  
Brown Seaweed ◽  
Amplicon Sequencing ◽  
Fucus Vesiculosus ◽  
Integrated Metabolomics

scholarly journals Clinical Efficacy of Brown Seaweeds Ascophyllum nodosum and Fucus vesiculosus in the Prevention or Delay Progression of the Metabolic Syndrome: A Review of Clinical Trials

Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 714
Author(s):  
Enver Keleszade ◽  
Michael Patterson ◽  
Steven Trangmar ◽  
Kieran J. Guinan ◽  
Adele Costabile
Keyword(s):  
Metabolic Syndrome ◽  
Clinical Trials ◽  
Brown Seaweed ◽  
Public Health Problem ◽  
Ascophyllum Nodosum ◽  
Fucus Vesiculosus ◽  
Total Phenolic ◽  
World Population ◽  
Brown Seaweeds ◽  
The Metabolic Syndrome

Metabolic syndrome (MetS) is a global public health problem affecting nearly 25.9% of the world population characterised by a cluster of disorders dominated by abdominal obesity, high blood pressure, high fasting plasma glucose, hypertriacylglycerolaemia and low HDL-cholesterol. In recent years, marine organisms, especially seaweeds, have been highlighted as potential natural sources of bioactive compounds and useful metabolites, with many biological and physiological activities to be used in functional foods or in human nutraceuticals for the management of MetS and related disorders. Of the three groups of seaweeds, brown seaweeds are known to contain more bioactive components than either red and green seaweeds. Among the different brown seaweed species, Ascophyllum nodosum and Fucus vesiculosus have the highest antioxidant values and highest total phenolic content. However, the evidence base relies mainly on cell line and small animal models, with few studies to date involving humans. This review intends to provide an overview of the potential of brown seaweed extracts Ascophyllum nodosum and Fucus vesiculosus for the management and prevention of MetS and related conditions, based on the available evidence obtained from clinical trials.

Copper, Zinc, Nickel, and Cobalt biosorption potential of Fucus vesiculosus (Phaeophyceae) and Gracilaria tikvahiae (Rhodophyta)

2009 ◽  
Vol 4 (2) ◽  
Author(s):  
A. Chaudhuri ◽  
M. Mitra ◽  
J.G. Schwarz ◽  
S. Schiewer
Keyword(s):  
Inductively Coupled Plasma ◽  
Brown Seaweed ◽  
Atomic Emission ◽  
Fucus Vesiculosus ◽  
Isotherm Models ◽  
Red Seaweed ◽  
Seaweed Species ◽  
Gracilaria Tikvahiae ◽  
Copper Zinc ◽  
Zinc Nickel

Dried raw and protonated biomasses of the brown seaweed Fucus vesiculosus and the red seaweed Gracilaria tikvahiae were used to study their biosorption performance for copper, zinc, nickel, and cobalt. Representative samples of both species were collected from Chincoteague Bay, Virginia. A series of “sorbate” or metal concentrations (10-450 mg L-1) were selected for each metal to compare the seaweeds' biosorption performance at pH 4.5 ± 0.1 and 25±1 °C. Samples were analyzed on Inductively Coupled Plasma-Atomic Emission Spectrometer (ICP-AES). Langmuir and Freundlich adsorption isotherm models for single solute systems were used to assess sorption performance. Both raw and protonated Fucus vesiculosus exhibited higher affinity for metal ions than Gracilaria tikvahiae, at both high and low ends of the concentration ranges. The protonated red seaweed species had maximum metal uptake values of 0.99 mequiv g-1 (copper), 0.39 mequiv g-1 (zinc), 0.66 mequiv g-1 (nickel) and 0.79 mequiv g-1 (cobalt). In comparison, protonated Fucus vesiculosus sorbed higher amounts (1.63, 1.10, 1.40, and 1.69 mequiv g-1 of the metals in the same order). The prospects of using the brown seaweed species in the treatment of industrial wastewaters in place of expensive, conventional ion-exchange resins are envisaged.

Structure-activity relationship of the pro- and anticoagulant effects of Fucus vesiculosus fucoidan

2014 ◽  
Vol 111 (03) ◽  
pp. 429-437 ◽  
Author(s):  
Cong Jiang ◽  
Sabine Knappe ◽  
Sabrina Reutterer ◽  
Christina Szabo ◽  
Michael Dockal ◽  
...  
Keyword(s):  
Charge Density ◽  
Biological Activities ◽  
Brown Seaweed ◽  
Structure Activity Relationship ◽  
Structural Features ◽  
Fucus Vesiculosus ◽  
Factor Ix ◽  
Activity Relationship ◽  
Structure Activity ◽  
The Impact

SummaryFucoidan is a highly complex sulfated polysaccharide commonly extracted from brown seaweed. In addition to their many biological activities, fucoidans have recently been demonstrated to inhibit or increase coagulation at different concentration ranges. Their structural features, i.e. molecular weight (Mw), Mw distribution, degree of sulfation, monosaccharide composition, and different linkages, are known to affect these activities. Therefore, structure-activity relationship (SAR) analysis of fucoidan is crucial for its potential use as a procoagulant. In this study, Fucus vesiculosus (F.v.) fucoidan was fractionated by charge and size as well as over- and desulfated to different degrees to yield preparations with various structural properties. The fractions’ pro- and anticoagulant activities were assessed by calibrated automated thrombography (CAT) and activated partial thromboplastin time (aPTT) assays. Binding to and inhibition of the anticoagulant protein tissue factor pathway inhibitor (TFPI) and the ability to activate coagulation via the contact pathway were also investigated. This paper discusses the impact of charge density, size, and sugar composition on fucoidan’s pro- and anticoagulant activities. Fucoidan requires a minimal charge density of 0.5 sulfates per sugar unit and a size of 70 sugar units to demonstrate desired procoagulant activities for improvement of haemostasis in factor VIII/factor IX-deficient plasma.

Brown Seaweed as an Indicator of Heavy Metals in Estuaries in South-West England

1973 ◽  
Vol 53 (3) ◽  
pp. 705-720 ◽  
Author(s):  
G. W. Bryan ◽  
L. G. Hummerstone
Keyword(s):  
Heavy Metals ◽  
Seasonal Changes ◽  
Intertidal Zone ◽  
Metal Contamination ◽  
Brown Seaweed ◽  
Fucus Vesiculosus ◽  
Contamination Factors ◽  
South West ◽  
Copper Zinc ◽  
South West England

Concentrations of copper, zinc, lead, manganese and iron in the brown seaweed Fucus vesiculosus have been measured in samples collected over its range of distribution in four estuaries having different degrees of metal contamination. Factors controlling the concentrations in the weed have been studied and include the concentrations of metals in the water, seasonal changes, the position of the weed in the intertidal zone and the particular portion of the plant which is analysed. It is concluded that analysis of the weed gives a reasonable indication of average conditions in the water at points along an estuary and provides a method of making comparisons with the same estuary in subsequent years or with other estuaries.

scholarly journals Extraction of sulfated polysaccharides by autohydrolysis of brown seaweed Fucus vesiculosus

2012 ◽  
Vol 25 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Rosa M. Rodríguez-Jasso ◽  
Solange I. Mussatto ◽  
Lorenzo Pastrana ◽  
Cristóbal N. Aguilar ◽  
José A. Teixeira
Keyword(s):  
Brown Seaweed ◽  
Fucus Vesiculosus ◽  
Sulfated Polysaccharides

scholarly journals Influence of Gender and Age of Brown Seaweed (Fucus vesiculosus) on Biochemical Activities of Its Aqueous Extracts

Foods ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 39
Author(s):  
Diogo Nunes ◽  
Rebeca André ◽  
Asma Ressaissi ◽  
Bernardo Duarte ◽  
Ricardo Melo ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
High Resolution Mass Spectrometry ◽  
Anthropogenic Impacts ◽  
Biological Activities ◽  
Brown Seaweed ◽  
Fucus Vesiculosus ◽  
Total Phenol Content ◽  
Extraction Temperature ◽  
Aqueous Extracts ◽  
Compound Identification

Fucus vesiculosus L. is a common coastal brown seaweed associated with various benefits to human health due to its phenolic content and nutrients and is used as food through different methods of consumption. This study aims to evaluate the influence of the seaweed’s gender and growth stage on different types of biological activities as well as its chemical constitution and elements present. Akin to food preparation, aqueous extracts of the seaweed were prepared at 25 °C (salad) and 100 °C (soup). Biological activities were determined by measuring total phenol content (TPC), antioxidant activity and inhibition of acetylcholinesterase (AChE). Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS/MS) was used for compound identification, and elemental analysis was carried out by using Total Reflection X-ray Fluorescence Spectrometry (TXRF). Older females and males had higher TPC compared to the new ones at 100 °C. Antioxidant activity depended on the extraction temperature but was higher for the youngest male at 100 °C. AChE inhibitory activity was higher for older males at 25 °C, but at 100 °C it was higher for older females. Primary metabolites and various phloroglucinol were the main compounds identified. Additionally, since this seaweed is often harvested in estuarine systems with high anthropogenic impacts, its safety was evaluated through the evaluation of the sample’s metal content. The heavy metals detected are within the limits established by various regulating entities, pointing to a safe food source.

Studies on metal content in the brown seaweed, Fucus vesiculosus, from the Archipelago of Stockholm

1988 ◽  
Vol 49 (4) ◽  
pp. 245-263 ◽  
Author(s):  
Å. Forsberg ◽  
S. Söderlund ◽  
A. Frank ◽  
L.R. Petersson ◽  
M. Pedersén
Keyword(s):  
Metal Content ◽  
Brown Seaweed ◽  
Fucus Vesiculosus

scholarly journals Mechanisms of Bioactivities of Fucoidan from the Brown Seaweed Fucus vesiculosus L. of the Barents Sea

Marine Drugs ◽  
2020 ◽  
Vol 18 (5) ◽  
pp. 275 ◽  
Author(s):  
Olga N. Pozharitskaya ◽  
Ekaterina D. Obluchinskaya ◽  
Alexander N. Shikov
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Radical Scavenging ◽  
Brown Seaweed ◽  
Fucus Vesiculosus ◽  
Thrombin Time ◽  
Dpp Iv ◽  
Management Of Complications ◽  
Cox 2 ◽  
Anti Inflammatory

The aim of this study was to elucidate some mechanisms of radical scavenging and the anti-inflammatory, anti-hyperglycemic, and anti-coagulant bioactivities of high molecular weight fucoidan from Fucus vesiculosus in several in vitro models. Fucoidan has displayed potent 1, 1-diphenyl-2-picryl hydrazil radical scavenging and reduction power activities. It significantly inhibits the cyclooxygenase-2 (COX-2) enzyme (IC50 4.3 μg mL−1) with a greater selectivity index (lg(IC80 COX-2/IC80COX-1), −1.55) than the synthetic non-steroidal anti-inflammatory drug indomethacin (lg(IC80 COX-2/IC80COX-1), −0.09). A concentration-dependent inhibition of hyaluronidase enzyme with an IC50 of 2.9 μg mL−1 was observed. Fucoidan attenuated the lipopolysaccharide-induced expression of mitogen-activated protein kinase p38. Our findings suggest that the inhibition of dipeptidyl peptidase-IV (DPP-IV) (IC50 1.11 μg mL−1) is one of the possible mechanisms involved in the anti-hyperglycemic activity of fucoidan. At a concentration of 3.2 μg mL−1, fucoidan prolongs the activated partial thromboplastin time and thrombin time by 1.5-fold and 2.5-fold compared with a control, respectively. A significant increase of prothrombin time was observed after the concentration of fucoidan was increased above 80 μg mL−1. This evidenced that fucoidan may have an effect on intrinsic/common pathways and little effect on the extrinsic mechanism. This study sheds light on the multiple pathways of the bioactivities of fucoidan. As far as we know, the inhibition of hyaluronidase and DPP-IV by high molecular fucoidan was studied for the first time in this work. Our results and literature data suggest that molecular weight, sulfate content, fucose content, and polyphenols may contribute to these activities. It seems that high molecular weight fucoidan has promising therapeutic applications in different pharmacological settings. Anti-oxidant, anti-inflammatory and anti-coagulant drugs have been used for the management of complications of COVID19. Taken as a whole, fucoidan could be considered as a prospective candidate for the treatment of patients with COVID19; however, additional research in this field is required.

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