scholarly journals Both sedentary time and physical activity are associated with cardiometabolic health in overweight adults in a 1 month accelerometer measurement

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Tanja Sjöros ◽  
Henri Vähä-Ypyä ◽  
Saara Laine ◽  
Taru Garthwaite ◽  
Minna Lahesmaa ◽  
...  
Keyword(s):  
Physical Activity ◽  
Insulin Resistance ◽  
Lipid Profile ◽  
Linear Models ◽  
Sedentary Time ◽  
Venous Blood ◽  
Plasma Lipid ◽  
Cardiometabolic Health ◽  
Cross Sectional ◽  
Overweight Adults

AbstractThe aim of this study was to examine the associations of cardiometabolic health markers with device-measured sedentary behavior (SB) duration and different intensities of physical activity (PA) among overweight working-aged adults with low self-reported PA levels. This cross-sectional analysis included 144 subjects (42 men) with mean age of 57 (SD 6.5) years and mean BMI of 31.7 (SD 4) kg/m2. SB and standing time, breaks in sedentary time, light PA (LPA) and moderate-to-vigorous PA (MVPA) were measured for 4 consecutive weeks (mean 25 days, SD 4) with hip-worn accelerometers. Fasting plasma glucose, insulin, HbA1c, triglycerides and total cholesterol, HDL and LDL were measured from venous blood samples. HOMA-IR index was calculated as a surrogate of insulin resistance. The associations were examined using linear models. LPA, MVPA, and daily steps associated with better insulin sensitivity and favorable plasma lipid profile, when adjusted for age, sex and BMI, whereas greater proportion of SB associated with insulin resistance and unfavorable lipid profile. As all PA intensities associated with better cardiometabolic health, the total daily duration of PA may be more relevant than intensity in maintaining metabolic health in overweight adults, if the current guidelines for PA are not met.Trial Registration: ClinicalTrials.gov NCT03101228, registered 05/04/2017, https://clinicaltrials.gov/show/NCT03101228.

scholarly journals The role of physical activity on blood factors, lipid profile, and liver enzymes of tile factory workers (A Case Study)

2020 ◽  
Author(s):  
MH Dashti khavidaki ◽  
AA Minaeifar ◽  
F Rassekh ◽  
A Baghiani
Keyword(s):  
Physical Activity ◽  
Lipid Profile ◽  
Liver Enzymes ◽  
Venous Blood ◽  
Dust Particles ◽  
Factory Workers ◽  
Cross Sectional ◽  
Tile Factory ◽  
Blood Factors

Introduction: Inhalation of dust particles is prone to chronic diseases, and regular exercise reduces the risk of cardiovascular disease and improves blood variables. The purpose of this study was to investigate the role of physical activity on blood factors, lipid profile, and liver enzymes in tile factory workers. Materials and Methods: This is a cross-sectional study. 70 workers who were eligible to participate in the study were selected based on the sampling method available at the workplace. According to the Beck questionnaire, 15 people were included in each active and inactive groups. After 12 hours of worker's last meal, 10 ml of venous blood was used to evaluate biochemical variables of Blood factors (RBC, Hematocrit, Hemoglobin, WBC), lipid profile (Cholesterol, Triglyceride). Liver enzyme (ALT, AST, ALP) tests of both groups were performed in the occupational medicine laboratory of Meybod city, and SPSS Ver.23 software was used for analysis. Results: The results showed that red blood cells (p = 0.003) and hemoglobin (p = 0.034) in the active group were significantly higher than the inactive group. Also triglyceride (p = 0.025) and cholesterol (p = 0.042) of liver enzymes, (p = 0.011) ALT and AST (p = 0.047) were significantly lower. Conclusion: It seems that physical activity can have a positive effect; it can improve blood factors, liver enzymes, and fat profile in workers. According to the results, tile factory workers can achieve the desired blood factors with minimal physical activity.

scholarly journals The Prevalence of Insulin Resistance and the Associated Risk Factors in a Sample of 14–18-Year-Old Slovak Adolescents

2020 ◽  
Author(s):  
Jana Jurkovicova ◽  
Katarina Hirosova ◽  
Diana Vondrova ◽  
Martin Samohyl ◽  
Zuzana Stefanikova ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Insulin Resistance ◽  
Venous Blood ◽  
Significant Risk ◽  
Lifestyle Changes ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
Lifestyle Risk Factors ◽  
Lifestyle Risk

The prevalence of cardiometabolic risk factors has increased in Slovakian adolescents as a result of serious lifestyle changes. This cross-sectional study aimed to assess the prevalence of insulin resistance (IR) and the associations with cardiometabolic and selected lifestyle risk factors in a sample of Slovak adolescents. In total, 2,629 adolescents (45.8% males) aged between 14 and 18 years were examined in the study. Anthropometric parameters, blood pressure, and resting heart rate were measured, fasting venous blood samples were analysed, and HOMA-IR was calculated. The mean HOMA-IR was 2.45±1.91 without a significant intersexual difference. IR (cut-off point for HOMA-IR=3.16) was detected in 18.6% of adolescents (19.8% males, 17.6% females). IR was strongly associated with overweight/obesity (especially central) and with almost all monitored cardiometabolic factors, except for TC and systolic BP in females. The multivariate model selected variables such as low level of physical fitness, insufficient physical activity, breakfast skipping, a small number of daily meals, frequent consumption of sweetened beverages, and low educational level of fathers as the significant risk factors of IR in adolescents. Recognizing the main lifestyle risk factors and early IR identification is important in terms of the performance of preventive strategies. Weight reduction, regular physical activity, and healthy eating habits can improve insulin sensitivity and decrease the incidence of metabolic syndrome, type 2 diabetes, and CVD in adulthood.

Standing time and daily proportion of sedentary time are associated with pain-related disability in a one month accelerometer measurement in adults with overweight or obesity

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Jooa Norha ◽  
Arto J. Hautala ◽  
Tanja Sjöros ◽  
Saara Laine ◽  
Taru Garthwaite ◽  
...  
Keyword(s):  
Physical Activity ◽  
Back Pain ◽  
Subjective Experience ◽  
Linear Models ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Cross Sectional ◽  
Standing Time ◽  
Visual Analog Scales ◽  
Overweight Or Obesity

Abstract Objectives The association between the subjective experience of pain-related disability (PRD) and device-measured physical activity (PA) and sedentary behavior (SB) in overweight and obese adults is not well known. The aim of this study was to investigate the associations of pain markers with accelerometer-measured SB duration and different intensities of PA among physically inactive middle-aged adults with overweight or obesity. Methods This cross-sectional analysis included 72 subjects (27 men) with mean age of 57.9 (SD 6.7) years and mean BMI of 31.6 (SD 4.1) kg/m2. SB and standing time (ST), breaks in sedentary time, light physical activity (LPA) and moderate-to-vigorous physical activity (MVPA) were measured for four consecutive weeks (mean 25 days, SD 4) with a hip-worn triaxial accelerometer. Headache, musculoskeletal pain, back pain, and PRD were assessed by visual analog scales (VAS) and using the Oswestry disability index (ODI). RAND-36 questionnaire was applied to assess health-related quality of life. The associations were studied by linear models. Results ST was positively and SB proportion was negatively associated with PRD when adjusted for age, sex, BMI, accelerometry duration, MVPA, pain medication use, and general health perceptions assessed by RAND-36. No associations were found between ST and back pain. SB or different PA intensities were not associated with pain experience at specific sites. Conclusions Longer daily ST, but not LPA or MVPA is associated with higher level of PRD. Correspondingly, higher proportion of SB is associated with lower level of PRD. This suggests that individuals with PRD prefer to stand, possibly to cope with pain. These results may highlight the importance of habitual standing behaviors in coping with experienced PRD in adults with overweight or obesity.

scholarly journals Dietary intake of energy and selected nutrients and plasma lipid profile in young women and men with different levels of physical activity

2013 ◽  
Vol 5 (1) ◽  
pp. 99-107
Author(s):  
Marzena Malara ◽  
Elżbieta Hübner-Woźniak
Keyword(s):  
Physical Activity ◽  
Dietary Intake ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Young Women ◽  
Venous Blood ◽  
Plasma Lipid ◽  
Blood Collection ◽  
Plasma Lipid Profile ◽  
Different Levels

Summary Study aim: The purpose was to assess dietary intake of energy and selected nutrients and plasma lipid profile in young women and men with different levels of physical activity. Material and methods: The research included a total of 116 female and male students at the University of Physical Education who differed in their levels of physical activity. Analysis of the diets was based on 24-hour dietary interviews collected over 4 days prior to blood collection. Concentrations of total cholesterol (TC), HDL cholesterol (HDL-C), and triacylglycerol (TG) were measured in venous blood. In addition, the concentration of LDL cholesterol (LDL-C) and the ratios of TC / HDL-C and LDL-C/HDL-C were calculated. Results: Women, regardless of their physical activity levels, were characterized by a significantly higher concentration of total cholesterol in plasma (4.8 and 4.5 mmol/L, respectively - in training participants; 4.7 and 4.3 mmol/L, respectively - in non-training participants), although their dietary intake of cholesterol was significantly lower in comparison with the corresponding groups of men (282.0 and 484.7 mg, respectively - in training participants; 252.6 and 400.2 mg, respectively - in non-training participants). A trend toward a worse lipid profile of training women and men compared with the corresponding groups of non-training participants was also observed. Conclusions: Increased physical activity in the groups of training women and men was not a sufficient stimulus to induce positive changes in their lipid profiles. Nor can it be excluded that the observed differences were the result of diet, as dietary intake of cholesterol in the groups of training women and men was higher compared with the corresponding groups of non-training participants.

scholarly journals Anthocyanin Intake and Physical Activity: Associations with the Lipid Profile of a US Working Population

Molecules ◽  
2020 ◽  
Vol 25 (19) ◽  
pp. 4398 ◽  
Author(s):  
Maria S. Hershey ◽  
Mercedes Sotos-Prieto ◽  
Miguel Ruiz-Canela ◽  
Miguel Angel Martinez-Gonzalez ◽  
Aedin Cassidy ◽  
...  
Keyword(s):  
Physical Activity ◽  
Lipid Profile ◽  
Linear Models ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Activity Level ◽  
Linear Regression Models ◽  
Cvd Risk ◽  
Cross Sectional ◽  
Validated Questionnaire

While growing evidence exists on the independent associations between anthocyanins and physical activity on cardiovascular disease (CVD) risk determinants, the possible interaction between these exposures has not yet been studied. We aimed to study the potential synergism between anthocyanin intake and physical activity on lipid profile measures. This cross-sectional study was conducted among 249 US career firefighters participating in the Feeding America’s Bravest trial. Anthocyanin intake was calculated using a validated food frequency questionnaire (FFQ) and physical activity level by a validated questionnaire. Multivariable linear regression models determined the extent to which anthocyanin intake and physical activity predicted lipid parameters. Generalized linear models were used for joint effect and interaction analyses on the multiplicative and additive scales. Both anthocyanins and physical activity were independently inversely associated with total cholesterol:high density lipoprotein (HDL) cholesterol. Only physical activity was inversely associated with triglycerides, low density lipoprotein (LDL) cholesterol:HDL, and triglycerides (TG):HDL. Although the combined exposure of low anthocyanin intake and low physical activity was associated with lower (RR = 2.83; 95% CI: 1.42 to 5.67) HDL cholesterol <40 mg/dL, neither multiplicative (p = 0.72) nor additive interactions were detected (relative excess risk due to interaction (RERI): 0.02; 95% CI: −1.63 to 1.66; p = 0.98). Our findings provide insight on the potential synergism between anthocyanin intake and physical activity on the lipid profile.

Abstract 19204: Higher Physical Activity and Lower Sedentary Time are Associated With Less Insulin Resistance and Favorable Adipokine Profile: The Framingham Study

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Nicole L Spartano ◽  
Meredith D Stevenson ◽  
Vanessa Xanthakis ◽  
Martin G Larson ◽  
Charlotte Andersson ◽  
...  
Keyword(s):  
Physical Activity ◽  
Insulin Resistance ◽  
Fatty Acid ◽  
Metabolic Diseases ◽  
Sedentary Time ◽  
Binding Protein ◽  
Retinol Binding Protein ◽  
Community Based ◽  
Cross Sectional ◽  
Fatty Acid Binding

Background: Physical activity (PA) and sedentary time (ST) are associated with metabolic diseases. More PA and less ST may also be associated with a more favorable adipokine profile and greater insulin sensitivity, even in the absence of weight loss. We tested this hypothesis by relating a comprehensive panel of adipokines in relation to accelerometry-determined PA measures in a community-based cohort. Methods: We assessed PA and ST using Actical accelerometers in 2109 participants from Framingham Heart Study Generation 3 and Omni 2 cohorts (mean age 40 y, 54% F) free of diabetes. Circulating adipokines, C-reactive protein (CRP), insulin-like growth factor (IGF)-1 and insulin resistance (HOMA-IR) were dependent variables, and steps/day, moderate to vigorous PA (MVPA), and ST/weartime were independent variables in multivariable regression analyses. We adjusted for cohort, age, sex, season of exam, overnight wear, residence (New England or other), body mass index (BMI), cardiovascular disease, hypertension, and smoking. Models for PA were also adjusted for ST, and models for ST also adjusted for MVPA. Results: Overall, 49% of participants met the PA Guidelines (>150 min/wk MVPA). Higher MVPA and more steps per day were associated with lower insulin resistance and CRP levels. More steps were also associated with lower leptin and higher IGF-1 levels. ST was positively associated with insulin resistance (p<0.001), but this relation was not significant after adjusting for MVPA. ST was associated with higher leptin, adipocyte fatty acid-binding protein (FABP)4 and retinol binding protein (RBP)4 levels. Conclusions: Our cross-sectional study of a community-based sample demonstrated associations of PA and ST with metabolic factors and several adipokines, after adjusting for BMI. These findings may provide clues linking PA to cardiometabolic risk by influencing insulin resistance and inflammation, compared to ST potentially modulating fatty acid binding proteins.

scholarly journals High-intensity activity is more strongly associated with metabolic health in children compared to sedentary time: a cross-sectional study of the I.Family cohort

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Jonatan Fridolfsson ◽  
Christoph Buck ◽  
Monica Hunsberger ◽  
Joanna Baran ◽  
Fabio Lauria ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Insulin Resistance ◽  
Blood Pressure ◽  
Body Mass Index ◽  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
Cross Sectional ◽  
Intensity Physical Activity

Abstract Background Physical activity (PA) during childhood is important for preventing future metabolic syndrome (MetS). To examine the relationship between PA and MetS in more detail, accurate measures of PA are needed. Previous studies have only utilized a small part of the information available from accelerometer measured PA. This study investigated the association between measured PA and MetS in children with a new method for data processing and analyses that enable more detailed interpretation of PA intensity level. Methods The association between PA pattern and risk factors related to MetS was investigated in a cross- sectional sample of children (n = 2592, mean age 10.9 years, 49.4% male) participating in the European multicenter I. Family study. The risk factors examined include body mass index, blood pressure, high-density lipoprotein cholesterol, insulin resistance and a combined risk factor score (MetS score). PA was measured by triaxial accelerometers and raw data was processed using the 10 Hz frequency extended method (FEM). The PA output was divided into an intensity spectrum and the association with MetS risk factors was analyzed by partial least squares regression. Results PA patterns differed between the European countries investigated, with Swedish children being most active and Italian children least active. Moderate intensity physical activity was associated with lower insulin resistance (R2 = 2.8%), while vigorous intensity physical activity was associated with lower body mass index (R2 = 3.6%), MetS score (R2 = 3.1%) and higher high-density lipoprotein cholesterol (R2 = 2.3%). PA of all intensities was associated with lower systolic- and diastolic blood pressure, although the associations were weaker than for the other risk factors (R2 = 1.5% and R2 = 1.4%). However, the multivariate analysis implies that the entire PA pattern must be considered. The main difference in PA was observed between normal weight and overweight children. Conclusions The present study suggests a greater importance of more PA corresponding to an intensity of at least brisk walking with inclusion of high-intense exercise, rather than a limited time spent sedentary, in the association to metabolic health in children. The methods of data processing and statistical analysis enabled accurate analysis and interpretation of the health benefits of high intensity PA that have not been shown previously.

scholarly journals The Prevalence of Insulin Resistance and the Associated Risk Factors in a Sample of 14–18-Year-Old Slovak Adolescents

2021 ◽  
Vol 18 (3) ◽  
pp. 909
Author(s):  
Jana Jurkovičová ◽  
Katarína Hirošová ◽  
Diana Vondrová ◽  
Martin Samohýl ◽  
Zuzana Štefániková ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Insulin Resistance ◽  
Venous Blood ◽  
Significant Risk ◽  
Lifestyle Changes ◽  
Skewed Distribution ◽  
Model Assessment ◽  
Lifestyle Risk Factors ◽  
Lifestyle Risk

The prevalence of cardiometabolic risk factors has increased in Slovakian adolescents as a result of serious lifestyle changes. This cross-sectional study aimed to assess the prevalence of insulin resistance (IR) and the associations with cardiometabolic and selected lifestyle risk factors in a sample of Slovak adolescents. In total, 2629 adolescents (45.8% males) aged between 14 and 18 years were examined in the study. Anthropometric parameters, blood pressure (BP), and resting heart rate were measured; fasting venous blood samples were analyzed; and homeostasis model assessment (HOMA)-insulin resistance (IR) was calculated. For statistical data processing, the methods of descriptive and analytical statistics for normal and skewed distribution of variables were used. The mean HOMA-IR was 2.45 ± 1.91, without a significant sex differences. IR (cut-off point for HOMA-IR = 3.16) was detected in 18.6% of adolescents (19.8% males, 17.6% females). IR was strongly associated with overweight/obesity (especially central) and with almost all monitored cardiometabolic factors, except for total cholesterol (TC) and systolic BP in females. The multivariate model selected variables such as low level of physical fitness, insufficient physical activity, breakfast skipping, a small number of daily meals, frequent consumption of sweetened beverages, and low educational level of fathers as significant risk factors of IR in adolescents. Recognizing the main lifestyle risk factors and early IR identification is important in terms of the performance of preventive strategies. Weight reduction, regular physical activity, and healthy eating habits can improve insulin sensitivity and decrease the incidence of metabolic syndrome, type 2 diabetes, and cardiovascular disease (CVD).

scholarly journals Is Active Lifestyle Related to Autonomic Nervous System Function and Lipid Profile in People with Overweight? A Study Pilot

2021 ◽  
Vol 13 (5) ◽  
pp. 2439
Author(s):  
Alexis Espinoza-Salinas ◽  
Edgardo Molina-Sotomayor ◽  
Johnattan Cano-Montoya ◽  
Jose Antonio Gonzalez-Jurado
Keyword(s):  
Physical Activity ◽  
Insulin Resistance ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Lipid Profile ◽  
Model Assessment ◽  
System Function ◽  
Autonomic Nervous System Function ◽  
Autonomic Nervous ◽  
Nervous System Function

Autonomic nervous system function is an important predictor of physical fitness. The objective of this study was to find out the associations of autonomic activity parameters, lipid profile, insulin concentrations, and insulin resistance in overweight men with the level of physical activity. A descriptive and correlational study was carried out in 28 overweight men: 14 physically active (PA) and 14 physically inactive (PI). The following variables were assessed: Level of physical activity, HRV (heart rate variability), basal insulin, HOMA-IR index (Homeostasis Model Assessment Insulin-Resistance), and lipid profile. The main results show a positive correlation between the spectral parameters of the HRV and total cholesterol (r = 0.24), LDL (r = 0.59), VLDL (r = 0.86), and insulin (r = 0.88) of sedentary people, evidencing a directly proportional correlation with BMI. We conclude that weight gain and a sedentary lifestyle are associated with an increase in sympathetic discharge, which, in turn, is associated with an increase in lipid profile and insulin levels.

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