scholarly journals Emulsion-based systems for fabrication of electrospun nanofibers: food, pharmaceutical and biomedical applications

RSC Advances ◽  
2017 ◽  
Vol 7 (46) ◽  
pp. 28951-28964 ◽  
Author(s):  
Nooshin Nikmaram ◽  
Shahin Roohinejad ◽  
Sara Hashemi ◽  
Mohamed Koubaa ◽  
Francisco J. Barba ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Electrospun Nanofibers ◽  
Bioactive Materials ◽  
Electrospinning Method

Encapsulation of bioactive materials and drugs using the emulsion electrospinning method.

scholarly journals Nanostructured Fibers Containing Natural or Synthetic Bioactive Compounds in Wound Dressing Applications

Materials ◽  
2020 ◽  
Vol 13 (10) ◽  
pp. 2407 ◽  
Author(s):  
Alexa-Maria Croitoru ◽  
Denisa Ficai ◽  
Anton Ficai ◽  
Natalia Mihailescu ◽  
Ecaterina Andronescu ◽  
...  
Keyword(s):  
Wound Healing ◽  
Healing Process ◽  
Electrospun Nanofibers ◽  
Natural Compounds ◽  
Electrospinning Process ◽  
Wound Dressings ◽  
Wound Healing Process ◽  
Skin Substitutes ◽  
Bioactive Constituents ◽  
Electrospinning Method

The interest in wound healing characteristics of bioactive constituents and therapeutic agents, especially natural compounds, is increasing because of their therapeutic properties, cost-effectiveness, and few adverse effects. Lately, nanocarriers as a drug delivery system have been actively investigated and applied in medical and therapeutic applications. In recent decades, researchers have investigated the incorporation of natural or synthetic substances into novel bioactive electrospun nanofibrous architectures produced by the electrospinning method for skin substitutes. Therefore, the development of nanotechnology in the area of dressings that could provide higher performance and a synergistic effect for wound healing is needed. Natural compounds with antimicrobial, antibacterial, and anti-inflammatory activity in combination with nanostructured fibers represent a future approach due to the increased wound healing process and regeneration of the lost tissue. This paper presents different approaches in producing electrospun nanofibers, highlighting the electrospinning process used in fabricating innovative wound dressings that are able to release natural and/or synthetic substances in a controlled way, thus enhancing the healing process.

Recent advances in electrospun nanofibers for some biomedical applications

2020 ◽  
Vol 144 ◽  
pp. 105224 ◽  
Author(s):  
Sally Sabra ◽  
Doaa M. Ragab ◽  
Mona M. Agwa ◽  
Sohrab Rohani
Keyword(s):  
Biomedical Applications ◽  
Electrospun Nanofibers ◽  
Recent Advances

scholarly journals Bioactive calcium phosphate–based glasses and ceramics and their biomedical applications: A review

2017 ◽  
Vol 8 ◽  
pp. 204173141771917 ◽  
Author(s):  
Md Towhidul Islam ◽  
Reda M Felfel ◽  
Ensanya A Abou Neel ◽  
David M Grant ◽  
Ifty Ahmed ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Biomedical Applications ◽  
Culture Medium ◽  
Glass Ceramics ◽  
Phosphate Glasses ◽  
Bioactive Materials ◽  
Test Parameters ◽  
Phosphate Buffered Saline ◽  
Hydroxyapatite Formation

An overview of the formation of calcium phosphate under in vitro environment on the surface of a range of bioactive materials (e.g. from silicate, borate, and phosphate glasses, glass-ceramics, bioceramics to metals) based on recent literature is presented in this review. The mechanism of bone-like calcium phosphate (i.e. hydroxyapatite) formation and the test protocols that are either already in use or currently being investigated for the evaluation of the bioactivity of biomaterials are discussed. This review also highlights the effect of chemical composition and surface charge of materials, types of medium (e.g. simulated body fluid, phosphate-buffered saline and cell culture medium) and test parameters on their bioactivity performance. Finally, a brief summary of the biomedical applications of these newly formed calcium phosphate (either in the form of amorphous or apatite) is presented.

Influence of Gelatin on the Wettability and Mechanical Properties of Nylon-6 Electrospun Nanofibers: Novel Mats for Biomedical Applications

2012 ◽  
Vol 2 (3) ◽  
pp. 286-290 ◽  
Author(s):  
Gopal Panthi ◽  
Nasser A. M. Barakat ◽  
Afeesh R. Unnithan ◽  
Salem S. Al-Deyab ◽  
Bishweshwar Pant ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Biomedical Applications ◽  
Electrospun Nanofibers ◽  
Nylon 6

scholarly journals Preparation of a Cage-Type Polyglycolic Acid/Collagen Nanofiber Blend with Improved Surface Wettability and Handling Properties for Potential Biomedical Applications

Polymers ◽  
2021 ◽  
Vol 13 (20) ◽  
pp. 3458
Author(s):  
Sofia El-Ghazali ◽  
Hisatoshi Kobayashi ◽  
Muzamil Khatri ◽  
Duy-Nam Phan ◽  
Zeeshan Khatri ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Biomedical Applications ◽  
Structural Integrity ◽  
Polyglycolic Acid ◽  
Electrospinning Process ◽  
Surface Wettability ◽  
Practical Utilization ◽  
Electrospinning Method ◽  
Nitrogen Treatment ◽  
Surgical Operations

Electrospun biobased polymeric nanofiber blends are widely used as biomaterials for different applications, such as tissue engineering and cell adhesion; however, their surface wettability and handling require further improvements for their practical utilization in the assistance of surgical operations. Therefore, Polyglycolic acid (PGA) and collagen-based nanofibers with three different ratios (40:60, 50:50 and 60:40) were prepared using the electrospinning method, and their surface wettability was improved using ozonation and plasma (nitrogen) treatment. The effect on the wettability and the morphology of pristine and blended PGA and collagen nanofibers was assessed using the WCA test and SEM, respectively. It was observed that PGA/collagen with the ratio 60:40 was the optimal blend, which resulted in nanofibers with easy handling and bead-free morphology that could maintain their structural integrity even after the surface treatments, imparting hydrophilicity on the surface, which can be advantageous for cell adhesion applications. Additionally, a cage-type collector was used during the electrospinning process to provide better handling properties to (PGA/collagen 60:40) blend. The resultant nanofiber mat was then incorporated with activated poly (α,β-malic acid) to improve its surface hydrophilicity. The chemical composition of PGA/collagen 60:40 was assessed using FTIR spectroscopy, supported by Raman spectroscopy.

scholarly journals Synthesis of Electrospun Nanofibers Membrane and Its Optimization for Aerosol Filter Application

2016 ◽  
Vol 1 ◽  
Author(s):  
Abdul Rajak
Keyword(s):  
Pressure Drop ◽  
Fiber Diameter ◽  
Polymer Concentration ◽  
Electrospun Nanofibers ◽  
Diameter Distribution ◽  
Air Filtration ◽  
Sem Image ◽  
Aerosol Filtration ◽  
Electrospinning Method ◽  
Fiber Diameter Distribution

Nanofibers membranes were synthesized using electrospinning method for air filtration application. Polyacrylonitrile (PAN) with three different concentrations as the polymeric matrix of the nanofibers membrane is used. In the aerosol filtration, the pressure drop is one of the most important parameters, which is determined by the membrane characteristics. One of the parameters that influence the characteristics of membrane is concentration of polymer solution, in which it will determine the diameter of fiber. In this study, the relation between the PAN concentration and the pressure drop in air filtration test was examined. Three different concentrations of PAN solution (6, 9, and 12 wt.%) were employed under the same process parameters of electrospinning. The fiber diameter distribution of each membrane was measured from its scanning electron microscope (SEM) image. The three concentrations resulted in significant different effect to the pressure drop that proved the existing correlation between the polymer concentration and the air pressure drop.

scholarly journals Adsorption Isotherms Study of Methylene Blue Dye on Membranes from Electrospun Nanofibers

2018 ◽  
Vol 34 (6) ◽  
pp. 2884-2894 ◽  
Author(s):  
Wedad J. Fendi ◽  
Juman A. Naser
Keyword(s):  
Methylene Blue ◽  
Adsorption Isotherms ◽  
Electrospun Nanofibers ◽  
Formaldehyde Resin ◽  
Blue Dye ◽  
Methylene Blue Dye ◽  
Electrospinning Method ◽  
Ftir Technique ◽  
Nanofiber Membranes ◽  
Langmuir And Freundlich Models

P-cresol formaldehyde resin was prepared and characterized by FTIR technique, then composited with polystyrene in order to produce electrospun nanofiber membrane by the electrospinning method. Zinc oxide nanoparticles was prepared and characterized by FTIR, XRD SEM and EDX techniques in order to modified first membrane. Both prepared nanofiber membranes characterized by SEM and EDX techniques and used as adsorbents to adsorb methylene blue dye from their aqueous solutions. The factors of adsorption were investigated, contact time, initial concentration, adsorbent dosage, ionic strength and temperature. The adsorption isotherms described by Langmuir and Freundlich models. So, thermodynamic functions ∆G, ∆H and ∆S of adsorption were estimated.

scholarly journals Quantifying the Adhesion of Silicate Glass–Ceramic Coatings onto Alumina for Biomedical Applications

Materials ◽  
2019 ◽  
Vol 12 (11) ◽  
pp. 1754 ◽  
Author(s):  
Francesco Baino
Keyword(s):  
Coating Thickness ◽  
Glass Ceramic ◽  
Bonding Strength ◽  
Biomedical Applications ◽  
Strain Energy Release ◽  
Ceramic Coatings ◽  
International Standards ◽  
Bioactive Materials ◽  
Glass Ceramic Coatings ◽  
Joint Prostheses

Deposition of bioactive glass or ceramic coatings on the outer surface of joint prostheses is a valuable strategy to improve the osteointegration of implants and is typically produced using biocompatible but non-bioactive materials. Quantifying the coating–implant adhesion in terms of bonding strength and toughness is still a challenge to biomaterials scientists. In this work, wollastonite (CaSiO3)-containing glass–ceramic coatings were manufactured on alumina tiles by sinter-crystallization of SiO2–CaO–Na2O–Al2O3 glass powder, and it was observed that the bonding strength decreased from 34 to 10 MPa as the coating thickness increased from 50 to 300 µm. From the viewpoint of bonding strength, the coatings with thickness below 250 µm were considered suitable for biomedical applications according to current international standards. A mechanical model based on quantized fracture mechanics allowed estimating the fracture toughness of the coating on the basis of the experimental data from tensile tests. The critical strain energy release rate was also found to decrease from 1.86 to 0.10 J/m2 with the increase of coating thickness, which therefore plays a key role in determining the mechanical properties of the materials.

BIOMEDICAL APPLICATIONS OF ELECTROSPUN NANOFIBERS

2020 ◽  
Vol 27 (11) ◽  
pp. 2030001
Author(s):  
ZHANG YANCONG ◽  
DOU LINBO ◽  
MA NING ◽  
WU FUHUA ◽  
NIU JINCHENG
Keyword(s):  
Biomedical Applications ◽  
Three Dimensional ◽  
Chemical Properties ◽  
Electrospun Nanofibers ◽  
High Porosity ◽  
Nanofiber Diameter ◽  
Surface Microscopy ◽  
Different Shapes ◽  
Physical And Chemical ◽  
And Chemical Properties

Electrospun technology is a simple and flexible method for preparation of nanofiber materials with unique physical and chemical properties. The nanofiber diameter is adjustable from several nanometers to few microns during the preparation. Electrospun nanofiber materials are easy to be assembled into different shapes of three-dimensional structures. These materials exhibit high porosity and surface area and can simulate the network structures of collagen fibers in a natural extracellular matrix, thereby providing a growth microenvironment for tissue cells. Electrospun nanofibers therefore have extensive application prospects in the biomedicine field, including in aerospace, filtration, biomedical applications, and biotechnology. Nanotechnology has the potential to revolutionize many fields, such as surface microscopy, silicon fabrication, biochemistry, molecular biology, physical chemistry, and computational engineering, while the advent of nanofibers has increased the understanding of nanotechnology among academia, industry, and the general public. This paper mainly introduces the application of nanofiber materials in tissue engineering, drug release, wound dressing, and other biomedicine fields.

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