Effects of Physical Training on Metabolic Control in Elderly Type 2 Diabetes Mellitus Patients

1997 ◽  
Vol 93 (2) ◽  
pp. 127-135 ◽  
Author(s):  
P.C. Ligtenberg ◽  
J.B.L. Hoekstra ◽  
E. Bol ◽  
M.L. Zonderland ◽  
D.W. Erkelens
Keyword(s):  
Physical Activity ◽  
Type 2 Diabetes ◽  
Insulin Sensitivity ◽  
Physical Training ◽  
Training Group ◽  
Control Group ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

1. The specific role of physical activity in the treatment of type 2 diabetes is still subject to discussion. A randomized prospective study was performed, investigating both the influence of physical training on metabolic control and the feasibility of physical training in the elderly. 2. A total of 58 patients (mean age: 62 ± 5 years; range: 55–75 years) with type 2 diabetes were randomized to either a physical training or a control programme. The training programme consisted of three sessions a week, aiming at 60–80% of the maximal oxygen uptake (VO2max). The 12 week supervised period was followed by a 14 week non-supervised one. The control group followed an educational programme. VO2max was assessed during exercise on a cycle ergometer. Glycosylated haemoglobin (HbA1c) was used as a measure for glucose control, and an insulin tolerance test was performed to test insulin sensitivity. Multivariate analysis of variance, with repeated measures design, was used to test differences between groups. 3. Fifty-one patients completed the study. VO2max was higher in the training group than in the control group both after 6 weeks (P ≤ 0.01 between groups) and after 26 weeks [training group: 1796 ± 419 ml/min (prestudy), 1880 ± 458 ml/min (6 weeks), 1786 ± 591 ml/min (26 weeks); control group: 1859 ± 455 ml/min (prestudy), 1742 ± 467 ml/min (6 weeks), 1629 ± 504 ml/min (26 weeks)]. Blood glucose control and insulin sensitivity did not change during the study. Levels of total triacyl-glycerols, very-low-density lipoprotein-triacyl-glycerols and apolipoprotein B were significantly lower after 6 weeks (P ≤ 0.01, P ≤ 0.05, P ≤ 0.05 between groups respectively), and so was the level of total cholesterol after 12 weeks of training (P ≤ 0.05 between groups). 4. Physical training in obese type 2 diabetic patients over 55 years of age does not change glycaemic control or insulin sensitivity in the short-term. Regular physical activity may lower triacylglycerol and cholesterol levels in this group of patients. 5. Finally, physical training in motivated elderly type 2 diabetic patients without major cardiovascular or musculoskeletal disorders is feasible, but only under supervision.

Effect of 10 days of bedrest on metabolic and vascular insulin action: a study in individuals at risk for type 2 diabetes

2010 ◽  
Vol 108 (4) ◽  
pp. 830-837 ◽  
Author(s):  
Mette P. Sonne ◽  
Amra C. Alibegovic ◽  
Lise Højbjerre ◽  
Allan Vaag ◽  
Bente Stallknecht ◽  
...  
Keyword(s):  
Physical Activity ◽  
Type 2 Diabetes ◽  
Insulin Sensitivity ◽  
High Sensitivity ◽  
Whole Body ◽  
Diabetic Patients ◽  
Activity Levels ◽  
Type 2 Diabetic Patients ◽  
Increased Risk

Physical inactivity is a known risk factor for type 2 diabetes. We studied whole body and forearm insulin sensitivity in subjects at increased risk for type 2 diabetes [persons with low birth weight (LBW group; n = 20) and first-degree relatives to type 2 diabetic patients (FDR group; n = 13)] as well as a control (CON) group ( n = 20) matched for body mass index, age, and physical activity levels before and after 10 days of bedrest. Subjects were studied by hyperinsulinemic isoglycemic clamp combined with arterial and deep venous catheterization of the forearm. Forearm blood flow (FBF) was measured by venous occlusion plethysmography. All groups responded with a decrease in whole body insulin sensitivity in response to bedrest [CON group: 6.8 ± 0.5 to 4.3 ± 0.3 mg·min−1·kg−1( P < 0.0001), LBW group: 6.2 ± 0.5 to 4.3 ± 0.3 mg·min−1·kg−1( P < 0.0001), and FDR group: 4.3 ± 0.7 to 3.1 ± 0.3 mg·min−1·kg−1( P = 0.068)]. The percent decrease was significantly greater in the CON group compared with the FDR group (CON group: 34 ± 4%, LBW group: 27 ± 4%, and FDR group: 10 ± 13%). Forearm insulin-stimulated glucose clearance decreased significantly in the CON and LBW groups in response to bedrest; in the FDR group, clearance was very low before bedrest and no change was observed. Before bedrest, the CON and LBW groups demonstrated a significant increase in FBF during hyperinsulinemia; after bedrest, an increase in FBF was observed only in the CON group. In conclusion, bedrest induced a pronounced reduction in whole body, skeletal muscle, and vascular insulin sensitivity in the CON and LBW groups. The changes were most pronounced in the CON group. In the FDR group, insulin resistance was already present before bedrest, but even this group displayed a high sensitivity to changes in daily physical activity.

scholarly journals Dietary Diversity as a Risk Factor for Obesity in Algerian Patients with Type 2 Diabetes Mellitus

Healthcare ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1229
Author(s):  
Abdenour Bounihi ◽  
Hamza Saidi ◽  
Asma Bouazza ◽  
Hassiba Benbaibeche ◽  
Malha Azzouz ◽  
...  
Keyword(s):  
Physical Activity ◽  
Type 2 Diabetes ◽  
Risk Factor ◽  
Dietary Diversity ◽  
Diabetic Patients ◽  
Obese Patients ◽  
Type 2 Diabetic Patients ◽  
Cross Sectional ◽  
Type 2 Diabetic

Although the incidence of “diabesity” (coexistence of type 2 diabetes and obesity) is alarmingly increasing in Algeria, the diet–diabesity link has not been well defined. This study aimed to explore the association between dietary diversity score (DDS) and obesity among Algerian type 2 diabetic patients. It was a cross-sectional observational study involving 390 type 2 diabetic patients. Anthropometric data were gathered, and dietary intake information was obtained through a 24-h dietary recall method, which was used to calculate DDS. Potential confounders such as age, sex, smoking, physical activity and energy intake were controlled for using multivariate logistic regression. A total of 160 patients (41.3%) were classified as obese. As expected, obese patients had a higher body mass index, waist circumference, hip circumference, body fat and fat mass index. Furthermore, obese patients more frequently met carbohydrate recommendations and had a higher intake of meat and protein. Female sex, hypertension, low physical activity and high meat and protein intake were positively associated with diabesity. Additionally, higher DDS was positively associated with diabesity after adjusting for confounders. Thus, a more diversified diet may be a risk factor for obesity among Algerian type 2 diabetic patients.

scholarly journals Effect of hypothyroidism on lipid profile of type 2 diabetic patients

2020 ◽  
Vol 7 (5) ◽  
pp. 754
Author(s):  
Damanpreet Singh ◽  
Gurinder Mohan ◽  
Arshdeep Bansal
Keyword(s):  
Type 2 Diabetes ◽  
Lipid Profile ◽  
Diabetic Complication ◽  
Control Group ◽  
P Value ◽  
Diabetic Patients ◽  
Study Group ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Background: Hypothyroidism is an endocrine disorder resulting from deficiency of thyroid hormones, and Diabetes is a metabolic disorder that share the phenotype of hyperglycaemia. Both the endocrinopathies have been found to be associated with dyslipidaemia and atherosclerosis that result into various complications. Our aim was to assess the difference of dyslipidaemia in patients suffering from hypothyroidism with diabetes as compared to diabetes alone.Methods: Study was conducted in department of medicine in SGRDIMSR, Sri Amritsar. A total of 120 patients were enrolled for the present study, the one who presented to hospital from January 2018 to August 2019 diagnosed with diabetes mellitus type 2. The patients were divided into two groups. 60 patients having type 2 diabetes without hypothyroidism (control group). 60 patients having type 2 diabetes with hypothyroidism (study group). Fasting lipid profile were performed in both the groups and were analysed for the study.Results: Dyslipidaemia was seen more in study group as compared to control group with mean cholesterol of 488.3(±144.43) and mean triglyceride levels of 354.30(±128.57) in study  group as compared to control group with mean cholesterol and triglyceride levels of 179.7(±81.47) and 177.08(±118.18) with p-value of 0.001 and 0.01 respectively which were significant. Also, obesity and diabetic complication were more in patients of dual endocrinopathies as compared to diabetes alone which were also significant statistically.Conclusions: From our study it is concluded that type 2 diabetes with hypothyroidism causes more dyslipidaemia as compare to type 2 diabetes alone. So proper screening of thyroid profile of type 2 diabetic patients and its correction helps in achieving better lipidemic control which further prevent complications.

scholarly journals Prescription of Physical Activity by General Practitioners in Type 2 Diabetes: Practice and Barriers in French Guiana

2022 ◽  
Vol 12 ◽  
Author(s):  
Stephanie Dranebois ◽  
Marie Laure Lalanne-Mistrih ◽  
Mathieu Nacher ◽  
Liliane Thelusme ◽  
Sandra Deungoue ◽  
...  
Keyword(s):  
Physical Activity ◽  
Type 2 Diabetes ◽  
General Practitioners ◽  
French Guiana ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Cross Sectional ◽  
Balanced Diet ◽  
Type 2 Diabetic

BackgroundGeneral practitioners (GPs) are the major primary healthcare players in the management of type 2 diabetes. In addition to a well-balanced diet, physical activity (PA) appears as a necessary non-medicinal therapy in the management of diabetic patients. However, GPs emphasize several obstacles to its prescription. The aim of this study is to evaluate the practices, barriers, and factors favoring the prescription of PA in type 2 diabetic patients by GPs in French Guiana.MethodWe conducted a cross-sectional descriptive study using a questionnaire, designed to interview 152 French Guiana GPs and describe their practice in prescribing PA in type 2 diabetic patients.ResultsOur results revealed that the prescription of PA as a non-medicinal therapeutic choice in the management of type 2 diabetes was practiced by 74% of the French Guiana GPs. However, only 37% of GPs responded that they implemented the recommendations; indeed, only one-third knew about them. The majority of GPs were interested in PA training, but only 11% were actually trained in this practice. The lack of structure adapted to the practice of PA and the lack of awareness of the benefits of PA in metabolic pathology appeared as the main obstacles to PA prescription.ConclusionThis study highlights the importance of improving the training of GPs in the prescription of PA, the development of adapted PA structures, and collaboration between the different actors within the framework of the sport-health system in type 2 diabetes in French Guiana.

scholarly journals FAKTOR-FAKTOR YANG BERPENGARUH TERHADAP TERJADINYA HIPERTENSI PADA PENDERITA DIABETES MELITUS TIPE II (Studi di Wilayah Puskesmas Kabupaten Pati)

2017 ◽  
Vol 13 (1) ◽  
pp. 47-59
Author(s):  
Gracilaria Puspa Sari ◽  
Marek Samekto ◽  
Mateus Sakundarno Adi
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Control Group ◽  
Case Group ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Chi Square ◽  
Type 2 Diabetic ◽  
Ethical Clearance

ENGLISHThe prevalence of hypertension in type 2 diabetic patients is 1,5-3 times higher than in nondiabetic The objectives of this research is to explain the risk factors affecting hypertension in type 2 diabetic patients. The research used an observational studies with case-control study design in Primary Healthcare Centers patients in Pati Regency of 2014. Case group were 57 patients with hypertension in type 2 diabetes, while control group were the type 2 diabetes patients without hypertension. Data were obtained from medical records and qualitative interviews. Chi-square test in bivariate and multiple logistic regression in multivariate analysis. This study has been obtained ethical clearance from The Ethical Committee of Health Research Medical Faculty of Diponegoro University or dr. Kariadi Hospital. Results : factors that influence hypertension in type 2 diabetic patients were physical activity (OR=6.4; 95% CI: 2.18-18.77; p=0.001), diabetes duration ≥ 5 years (OR=5.4; 95% CI: 1.97 – 14.704; p=0.001), and medication adherence (OR=3.6; 95% CI: 1.32-9.83; p=0.012). Other risk factors that not significantly influenced were age ≥45 years, male, diet compliance, history of hypertension, smoking, salt consumption, coffee consumption, and sleep duration. INDONESIAPrevalensi hipertensi pada penderita DM tipe 2 lebih tinggi dibandingkan non DM tipe 2. Tujuan penelitian untuk menjelaskan faktor yang berpengaruh terhadap terjadinya hipertensi pada penderita DM tipe 2 di wilayah kerja Puskesmas Kabupaten Pati tahun 2014. Jenis Penelitian observasional dengan rancangan studi kasus kontrol pada pasien Puskesmas. Kelompok kasus adalah 57 pasien DM tipe 2 dengan hipertensi sedangkan kelompok kontrol adalah 57 pasien DM tipe 2 tanpa hipertensi. Data diperoleh dari observasi catatan medis dan wawancara. Uji chi-square pada analisis bivariat dan analisis multivariat dengan regresi logistik ganda. Penelitian ini telah memdapatkan Ethical clearance dari Komisi Etik FK UNDIP/RSUP dr. Kariadi Semarang. Hasil Penelitian : faktor yang berpengaruh terhadap terjadinya hipertensi pada penderita DM tipe 2 adalah aktivitas fisik kurang (OR=6,4; 95% CI: 2,18 - 18,77; p=0,001), lama menderita DM ≥5 tahun (OR=5,4; 95% CI: 1,97 - 14,704; p=0,001), dan kepatuhan minum obat DM (OR=3,6; 95% CI: 1,32 - 9,83; p=0,012). Faktor yang tidak berpengaruh adalah : usia ≥45 tahun, jenis kelamin laki-laki, kepatuhan diet DM, riwayat hipertensi, kebiasaan merokok, kebiasaan makan asin, kebiasaan minum kopi, dan lama waktu tidur.

scholarly journals Effect of Different HIIT Protocols on the Glycemic Control and Lipids Profile in Men with type 2 diabetes: A Randomize Control Trial

2020 ◽  
Author(s):  
Hessam Golshan ◽  
Mohammadreza Esmaelzadeh Toloee ◽  
Hamid Abbasi ◽  
Nasim Namiranian
Keyword(s):  
Type 2 Diabetes ◽  
High Volume ◽  
Control Group ◽  
P Value ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Significant Difference ◽  
Low Volume ◽  
Type 2 Diabetic

Objective: : High intensity interval training (HIITs) can induce weight control, lowering blood pressure and beneficial effects on cardiovascular health in type 2 diabetic patients. The effect of different volumes of these exercises is unclear in type 2 diabetic patients. The aim of this study was to compare the effect of low volume and high volume of short-term intensive training on glycemic indexes of men with type 2 diabetes. Materials and Methods: Thirty type 2 diabetes male patients who were referred to Yazd diabetes research center (30 - 46 years old) were selected and randomly divided into 3 groups of low and high volume HIITs groups and control group. The intensity of the exercises in low volume was up to 110% and in high volume up to 80% of the maximum heart rate. The two training groups performed exercises 3 days of week for 8 weeks. Glycemic factors and lipids profile were measured before and after the last training session. Data were analyzed by covariance and paired T-test. Results: Low volume HIIT exercises significantly decreased the glucose ( P -value: 0.01), HbA1c ( P -value: 0.01), insulin ( P -value: 0.005), insulin resistance ( P -value: 0.001), and triglyceride ( P -value: 0.04). Low volume HIIT in the insulin resistance had a significant difference with the control group ( P -value: 0.04). High density lipoprotein in high volume group had a significant difference with the control group ( P -value: 0.021). Conclusion: Low-volume HIIT exercises can be a nonpharmacological approach to improving glycemic factors in type 2 diabetic patients.

scholarly journals Faktor Risiko yang Berpengaruh terhadap Terjadinya Hipertensi pada Penderita Diabetes Melitus Tipe II di Wilayah Puskesmas Kabupaten Pati

2017 ◽  
Vol 2 (2) ◽  
pp. 54
Author(s):  
Gracilaria Puspa Sari ◽  
Shofa Chasani ◽  
Tjokorda Gde Dalem Pemayun ◽  
Suharyo Hadisaputro ◽  
Heri Nugroho
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Medication Adherence ◽  
Coffee Consumption ◽  
Diabetes Duration ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Background: The prevalence of hypertension in type 2 diabetic patients is 1,5-3 times higher than it is in nondiabetic individuals This chronic condition accelerates macrovascular complications. Research about risk factors of hypertension in type 2 diabetic patients is still rare because its causes multifactorial. The objectives of this research is to explain the risk factors affecting hypertension in type 2 diabetic patients.Methods: An observational studies with case-control study design in Primary Healthcare Centers patients in Pati District. Patients with hypertension in type 2 diabetes are the case, while the type 2 diabetes patients without hypertension are the control. There were 57 cases and 57 controls included. Data were obtained from medical records and qualitative interviews. Chi-square test in bivariate and multiple logistic regression in multivariate analysis.Results: Factors that influence hypertension in type 2 diabetic patients were physical activity (OR=6,4; 95% CI: 2,18 - 18,77; p=0,001), diabetes duration ≥ 5 years (OR=5,4; 95% CI: 1,97 - 14,704; p=0,001), and medication adherence (OR=3,6; 95% CI: 1,32 - 9,83; p=0,012). Other risk factors i.e age ≥45 years, male, diet compliance, history of hypertension, smoking, salt consumption, coffee consumption, and sleep duration were not significantly influenced.Conclusion: In this study, physical activity, diabetes duration, and DM medication adherence are risk factors that influence of hypertension in type 2 diabetic patients. 

scholarly journals Mild cognitive impairment among type 2 diabetic patients attending Zagazig University outpatient clinics

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
N H Elshamy ◽  
I I Salama ◽  
M S Gabal ◽  
A M Hassan ◽  
G A Abdellatif
Keyword(s):  
Type 2 Diabetes ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Disorders ◽  
Outpatient Clinics ◽  
Control Group ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Abstract Objective The incidence of mild cognitive impairment increases with age, so this study is conducted to assess the relation between mild cognitive impairment and type 2 diabetes. Methods 100 type 2 diabetic patients attending Zagazig University outpatient clinics with age range from 40-60 years old was included in the study. These patients were matched with 100 non-diabetic controls regarding age, sex and educational class. Patients with important risk factors for cognitive disorders (cerebro-vascular stroke, organ failure, mental disorders, etc.) were not included in the study. Montreal cognitive assessment (MoCA) was done for all participants by an expert examiner using MoCA tool. Results Mild cognitive impairment was confirmed in 22% of diabetic patients and in 9% of control group (p &lt; 0.05) with total MoCA score lower in diabetic group than control one (p &lt; 0.01). Conclusion Type 2 diabetes may be associated with lower levels of cognitive function.

scholarly journals Effect of physical training on insulin sensitivity in Japanese type 2 diabetic patients: role of serum triglyceride levels

Diabetes Care ◽  
2000 ◽  
Vol 23 (6) ◽  
pp. 857-858 ◽  
Author(s):  
A. Taniguchi ◽  
M. Fukushima ◽  
M. Sakai ◽  
S. Nagasaka ◽  
K. Doi ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Physical Training ◽  
Serum Triglyceride ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

scholarly journals Faktor Risiko yang Berpengaruh terhadap Terjadinya Hipertensi pada Penderita Diabetes Melitus Tipe II di Wilayah Puskesmas Kabupaten Pati

2017 ◽  
Vol 2 (2) ◽  
pp. 54
Author(s):  
Gracilaria Puspa Sari ◽  
Shofa Chasani ◽  
Tjokorda Gde Dalem Pemayun ◽  
Suharyo Hadisaputro ◽  
Heri Nugroho
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Medication Adherence ◽  
Coffee Consumption ◽  
Diabetes Duration ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Background: The prevalence of hypertension in type 2 diabetic patients is 1,5-3 times higher than it is in nondiabetic individuals This chronic condition accelerates macrovascular complications. Research about risk factors of hypertension in type 2 diabetic patients is still rare because its causes multifactorial. The objectives of this research is to explain the risk factors affecting hypertension in type 2 diabetic patients.Methods: An observational studies with case-control study design in Primary Healthcare Centers patients in Pati District. Patients with hypertension in type 2 diabetes are the case, while the type 2 diabetes patients without hypertension are the control. There were 57 cases and 57 controls included. Data were obtained from medical records and qualitative interviews. Chi-square test in bivariate and multiple logistic regression in multivariate analysis.Results: Factors that influence hypertension in type 2 diabetic patients were physical activity (OR=6,4; 95% CI: 2,18 - 18,77; p=0,001), diabetes duration ≥ 5 years (OR=5,4; 95% CI: 1,97 - 14,704; p=0,001), and medication adherence (OR=3,6; 95% CI: 1,32 - 9,83; p=0,012). Other risk factors i.e age ≥45 years, male, diet compliance, history of hypertension, smoking, salt consumption, coffee consumption, and sleep duration were not significantly influenced.Conclusion: In this study, physical activity, diabetes duration, and DM medication adherence are risk factors that influence of hypertension in type 2 diabetic patients. 

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