scholarly journals Index of epithelization rate of thermal burns in laboratory animals when application of the “acerbin” preparation

2022 ◽  
Vol 42 ◽  
pp. 01004
Author(s):  
Alexander Nikolaevich Pereverzev ◽  
Vladimir Aleksandrovich Tolkachev

Thermal burns in animals represent an urgent problem for veterinary medicine, since the anti-burn drugs available on the world pharmacological market are not always adapted for use on animals and are approved for use in veterinary medicine. In this regard, the aim of the work was to use the wound healing spray “Acerbin” for medical purposes in the treatment of thermal burns and to evaluate its therapeutic efficacy by the rate of epithelialization of burn defects in the skin in laboratory animals. The work was carried out at the Department of Surgery and Therapy of the Kursk State Agricultural Academy, on laboratory white mice in the amount of 60 individuals, in which thermal burns were simulated in the croup and treated with applications of the Acerbin spray. To assess the rate of growth of epithelialization, planimetric measurements of the area of burns were carried out before treatment on the 3rd, 5th, 7th, 10th and 14th days of treatment, as well as the corresponding mathematical calculations of the rate of reduction of burn defects. According to the research results, it was found that when applying the Acerbin spray, the burn rate index on the 3rd day was 0.25 ± 0.06; on the 5th day 0.58 ± 0.03; on the 7th day 0.74 ± 0.01; on the 10th day 0.86 ± 0.02; on the 14th day 0.95 ± 0.01. Thus, at the end of the therapeutic period, the index of the epithelialization rate of thermal burns approached the most physiologically justified numerical expression equal to “1.0”, which allows it to be recommended for use in veterinary medicine as the preparation of choice for the treatment of thermal burns of the skin in animals.

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Afzal Hussain ◽  
Ashfaq Hussain ◽  
Chandan Kumar Verma

: Nigella sativa (Family Ranunculaceae) is a common medicinal plant all across the world. It is quite popular in different traditional medicinal systems such as Unani, Ayurveda, Tibb, and Siddha. Oil and Seeds have a long tradition of folk medicine utilized in different medicinal systems and food. The seeds of N. Sativa have indeed been widely applied in the treatment of many diseases, ailments, and also the immune booster. Our goal primarily concentrated on the therapeutic efficacy of Nigella sativa in combating the COVID-19 pandemic.


Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 648
Author(s):  
Michela Pugliese ◽  
Vito Biondi ◽  
Enrico Gugliandolo ◽  
Patrizia Licata ◽  
Alessio Filippo Peritore ◽  
...  

Chelant agents are the mainstay of treatment in copper-associated hepatitis in humans, where D-penicillamine is the chelant agent of first choice. In veterinary medicine, the use of D-penicillamine has increased with the recent recognition of copper-associated hepatopathies that occur in several breeds of dogs. Although the different regulatory authorities in the world (United States Food and Drugs Administration—U.S. FDA, European Medicines Agency—EMEA, etc.) do not approve D-penicillamine for use in dogs, it has been used to treat copper-associated hepatitis in dogs since the 1970s, and is prescribed legally by veterinarians as an extra-label drug to treat this disease and alleviate suffering. The present study aims to: (a) address the pharmacological features; (b) outline the clinical scenario underlying the increased interest in D-penicillamine by overviewing the evolution of its main therapeutic goals in humans and dogs; and finally, (c) provide a discussion on its use and prescription in veterinary medicine from a regulatory perspective.


2018 ◽  
Vol 19 (4) ◽  
Author(s):  
Tadeusz Wolski ◽  
Bogdan Kędzia

A cup plant (Silphium perfoliatum L.) is a poorly-known crop in the country. It came to Europe from North America in the 18th century. It can be propagated by dividing rhizomes or by sowing seeds. This plant is undemanding in terms of alimentary requirements and resistant to cold and pests. Due to the high content of nutrients and the yield of green mass a cup plant is used for fodder purposes. A cup plant contains numerous secondary metabolites, such as phenolic acids, flavonoids, terpenes, essential oil, tannins, vitamins and mineral components. It is characterized by antioxidant, antibacterial, antifungal, cytostatic and immunosuppressive activity. Research on laboratory animals indicates that the cup plant accelerates wound healing and indicate hypolipemic and estrogenic activity. Numerous reports confirm, that this plant also has a strengthening, diuretic, anti-inflammatory, antihemorrhagic and spasmolytic activity. In addition, it is used in the healing diseases of the liver and spleen, and also heals gastric and duodenal ulcers.


2021 ◽  
Vol 18 ◽  
Author(s):  
Damilare Rotimi ◽  
Jennifer Chidubem Amanze ◽  
Adebola Busola Ojo ◽  
Matthew Iyobhebhe ◽  
Tobiloba Christiana Elebiyo ◽  
...  

Abstract: The use of herbal remedies for medicinal purposes is becoming more popular around the world. As a result, plants have become viable treatment options for a variety of diseases. Garcinia kola (bitter kola) is a perennially grown plant in the Guttiferae family that has been evaluated and reported to have numerous health-promoting properties. Kolaviron is a biflavanoid and major phytochemical found in Garcinia kola that includes Garcinia Biflavanoid-1 (GB-1), kolaflavanone, and Garcinia Biflavanoid-2 (GB-2). It is obtained as a fraction extracted from Garcinia kola. Kolaviron's pharmacological properties include anti-inflammatory, anti-spasmodic, ameliorative, anti-asthmatic, anti-cancer, anti-malarial, hepatoprotective, antioxidant, anti-atherogenic, neuroprotective, anti-diabetic, and anti-amnesic properties. Kolaviron is recommended for use in clinical settings because it has been shown to have a high therapeutic efficacy in clinical trials. The purpose of this review is to assess the therapeutic efficacy of kolaviron.


2010 ◽  
Vol 64 (1-2) ◽  
pp. 143-149
Author(s):  
Silvestra Kobal

Doctors and veterinarians in many countries of the world have an opportunity to select between allopathic or homeopathic drugs. The selection of an appropriate method for medical treatment should be performed from the individual point of view. .


2021 ◽  
Vol 134 (3) ◽  
pp. 11-17
Author(s):  
I. G. Yashchenko ◽  
◽  
Y. M. Polishchuk ◽  

The article is devoted to the urgent problem of studying the features of the properties of poorly studied oils at great depths (more than 4,500 m), the need for development of which is caused by the continuing decline in oil production in traditional oil producing provinces. The analysis of the spatial distribution of reserves across the continents and countries of deep-seated oils and changes in their physico-chemical properties and the occurrence conditions, which made it possible to identify their main features. The studies used information on 21067 oil samples from 167 oil-bearing basins of the world, obtained from the database on the physicochemical properties of oils. The features of the physicochemical properties of deep-seated oils have been established, which are manifested in a decrease in the density and viscosity of oils, in a decrease in the content of sulfur and asphalt-resinous substances, and in an increase in the content of light fractions and oil gas in comparison with oils of small and medium depths.


2020 ◽  
Vol 66 (3) ◽  
pp. 56-65
Author(s):  
Filip Przerwa ◽  
Arnold Kukowka ◽  
Izabela Uzar

Abstract Ballota nigra, also known as black horehound is a common medical herb used in folk medicine around the world. First reported mentions of its medical properties and use goes as far as the 13th century. The use of black horehound depends on regions and countries. It is used mostly to treat e.g. mild sleep disorders, nervousness, upset stomach, wound healing. It can be used as an anti-inflammatory, antibacterial, antiprotozoal, antifungal drug. Moreover, it has been reported as a potential cancer drug. This extensive usage is particularly interesting for us. The aim of this review is to present available data on B. nigra pharmacological effects and known traditional uses gathered from a wide range of scientific articles published in 1997–2020.


2022 ◽  
pp. 431-453
Author(s):  
Mohammed Rahmatullah ◽  
Khoshnur Jannat ◽  
Gerald R. Reeck ◽  
Rownak Jahan ◽  
Taufiq Rahman ◽  
...  

Cyperus rotundus (nut grass in English) is a perennial erect sedge plant and is distributed in over 90 countries of the world, where it has been mostly classified as a highly invasive weed. Despite this classification, the plant has been considered from traditional times to be medicinally important. The traditional uses of the plant in various countries include uses against various gastrointestinal tract disorders, skin diseases, leprosy, fever, and neurological disorders. Evaluation of the plant and especially its rhizomes in a scientific manner has revealed the presence of numerous phytochemicals and wide-ranging pharmacological activities, which include anti-microbial, gastrointestinal, wound healing, anti-diabetic, anti-cancer, anti-malarial, anti-obesity, hepatoprotective, and anti-pyretic activity. The scientific validation of a number of traditional uses strongly indicates that the plant may prove useful in the discovery of a number of lead compounds and novel drugs.


Author(s):  
Mohammed Rahmatullah ◽  
Khoshnur Jannat ◽  
Gerald R. Reeck ◽  
Rownak Jahan ◽  
Taufiq Rahman ◽  
...  

Cyperus rotundus (nut grass in English) is a perennial erect sedge plant and is distributed in over 90 countries of the world, where it has been mostly classified as a highly invasive weed. Despite this classification, the plant has been considered from traditional times to be medicinally important. The traditional uses of the plant in various countries include uses against various gastrointestinal tract disorders, skin diseases, leprosy, fever, and neurological disorders. Evaluation of the plant and especially its rhizomes in a scientific manner has revealed the presence of numerous phytochemicals and wide-ranging pharmacological activities, which include anti-microbial, gastrointestinal, wound healing, anti-diabetic, anti-cancer, anti-malarial, anti-obesity, hepatoprotective, and anti-pyretic activity. The scientific validation of a number of traditional uses strongly indicates that the plant may prove useful in the discovery of a number of lead compounds and novel drugs.


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