scholarly journals Cervical Cancer Registered in Two Developed Regions from Brazil: Upper Limit of Reachable Results from Opportunistic Screening

2018 ◽  
Vol 40 (06) ◽  
pp. 347-353 ◽  
Author(s):  
Julio Teixeira ◽  
Carlos Maestri ◽  
Helymar Machado ◽  
Luiz Zeferino ◽  
Newton Carvalho
Keyword(s):  
Cervical Cancer ◽  
Screening Program ◽  
Age Groups ◽  
Cancer Registries ◽  
Trend Test ◽  
Opportunistic Screening ◽  
Age Group ◽  
Number Pattern ◽  
Armitage Trend Test ◽  
Histologic Types

Objective The aim of this study was to assess the time trends and pattern of cervical cancer diagnosed in the period from 2001 to 2012 by means of an opportunistic screening program from two developed regions in Brazil. Methods An observational study analyzing 3,364 cancer records (n = 1,646 from Campinas and n = 1,718 from Curitiba region) available in hospital-based cancer registries was done. An additional 1,836 records of CIN3/AIS from the region of Campinas was analyzed. The statistical analysis assessed the pooled data and the data by region considering the year of diagnosis, age-group, cancer stage, and histologic type. The Cochran-Armitage trend test was applied and p-values < 0.05 were considered significant. Results The total annual cervical cancer registered from 2001 to 2012 showed a slight drop (273–244), with an age average of 49.5 y, 13 years over the average for CIN3/AIS (36.8 y). A total of 20.6% of the diagnoses (1.6% under 25 y) were done out of the official screening age-range. The biennial rate of diagnoses by age group for the region of Campinas showed an increase trend for the age groups under 25 y (p = 0.007) and 25 to 44 y (p = 0.003). Stage III was the most recorded for both regions, with an annual average of 43%, without any trend modification. There was an increasing trend for stage I diagnoses in the region of Campinas (p = 0.033). The proportion of glandular histologic types registered had an increased trend over time (p = 0.002), higher for the region of Campinas (21.1% versus 12.5% for the region of Curitiba). Conclusion The number, pattern and trends of cervical cancer cases registered had mild and slow modifications and reflect the limited effectivity of the opportunistic screening program, even in developed places.

scholarly journals Pattern of Cervical Screening Utilization in Italy

1989 ◽  
Vol 75 (5) ◽  
pp. 420-422 ◽  
Author(s):  
Monica Ferraroni ◽  
Carlo La Vecchia ◽  
Romano Pagano ◽  
Eva Negri ◽  
Fabio Parazzini ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Screening Program ◽  
Cervical Screening ◽  
Age Groups ◽  
National Health Survey ◽  
Italian Population ◽  
Common Procedure ◽  
Quantitative Evidence ◽  
Italian Women ◽  
Substantial Decline

The pattern of cervical screening utilization in Italy was analyzed using data from the 1986-1987 National Health Survey on the basis of a sample of 27,455 women aged 20 to 79 randomly selected within strata of municipality of residence and age in order to be representative of the whole Italian population. Overall, about 17% of women aged 20 to 79 were screened per year, for a total of 3.5 to 4 million cervical smears per year. The highest frequency was reported in younger middle age, about one in four women being screened per year in the age groups 30 to 49, and there was a substantial decline above age 50. Cervical smear rates were higher in Northern areas (22 %), where mortality from cervical cancer is lower, than in the Centre (16%) and South (11 %) of the country. Further, there was a strong positive social class gradient in the utilization of cervical screening, in relation to both education and occupation. In spite of the absence of any organised mass screening program, cervical screening is a relatively common procedure among Italian women. However, this study provides further quantitative evidence of a markedly irrational utilization of non-organized cervical screening, which tends to end up selectively used by the groups in which cervical cancer is less common.

scholarly journals Socio-demographic and Clinical Characteristic of Women Availing Pap Smear Services in Samtse District, Bhutan

2020 ◽  
Vol 5 (2) ◽  
pp. 63-70
Author(s):  
Thinley Dorji ◽  
Hari Prasad Pokhrel ◽  
Tshokey Tshokey
Keyword(s):  
Cervical Cancer ◽  
Pap Smear ◽  
Screening Program ◽  
Age Groups ◽  
Malignant Lesion ◽  
Pap Test ◽  
Reproductive Age ◽  
Test Results ◽  
Malignant Lesions ◽  
Reproductive Age Group

Background: The case burden of cervical cancer has been increasing globally especially in developing countries without proper health system. Cervical cancer can be eliminated with timely vaccination and screening program as it usually takes years for pre-malignant lesions to develop into malignant lesion. Bhutan has committed to eliminate cervical cancer. Thus, it is important to understand the factors associated with abnormal Pap test findings. Methodology: A retrospective study was conducted using the Pap smear data for the year 2018. It was extracted from the records maintained in the cytology unit of Samtse General Hospital. Result: The abnormal slide rate in this study was 2.5%. The majority of women seeking Pap smear services were women in reproductive age group and housewife by occupation. There were significant differences between age groups and marital status among normal in the Pap test results. Conclusion: The slide abnormality of Pap smear in Samtse District is low. The abnormality is more common among married and older women. Therefore, additional screening efforts needs to be put into this group to detect pre-malignant lesions.

scholarly journals Analysis on the Incidence, Staging and Treatment of Carcinoma Cervix at Delta Medical College and Hospital of Bangladesh

2013 ◽  
Vol 1 (2) ◽  
pp. 31-36
Author(s):  
Parvin A Banu ◽  
Naheed Rukhsana ◽  
Jebunnessa Yasmin ◽  
Lutfun Nahar ◽  
Sadiqur R Malik
Keyword(s):  
Cervical Cancer ◽  
Screening Program ◽  
External Beam Radiotherapy ◽  
Concurrent Chemotherapy ◽  
Time Interval ◽  
Age Group ◽  
Carcinoma Cervix ◽  
Cross Sectional ◽  
Medical College ◽  
Incidence And Mortality

Background: Cervical cancer remains the most common cancer among women in this part of the world. Bangladesh has the highest level of incidence and mortality rates due to cervical cancer among women. Cervical cancer is a preventable disease by screening and treatment of pre-invasive condition. Unfortunately, there is no effective screening program in Bangladesh. Objective: The objective was to analyze the clinico-pathologic characteristics and, subsequently the therapy delivered to the patients. Materials and method: This cross sectional study was done from January to December 2011 in oncology division of Delta Medical College and Hospital, Dhaka, Bangladesh. During this period a total of 2264 female carcinoma patients were registered. Out of them 523 patients were with the diagnosis of carcinoma of cervix. Evaluation and characterization of patients with carcinoma cervix were done according to the age group, clinical stages and surgical status. External beam radiotherapy (EBRT) and doses, brachytherapy doses and fractions, time interval between EBRT and brachytherapy, neo-adjuvant and concurrent chemotherapy status were the factors taken into consideration for the analysis of treatment of these patients. Results: The study revealed that the incidence of carcinoma cervix was 23% and highest incidence was between 40-50 years of age group, most of the patients were in Stage IIB (34%) and IIIB (28%) and 31% with unknown stage. About 44% patients were referred postoperatively and most of them with unknown stage. Almost 90% patients received EBRT, 24% patients received concurrent chemo-radiation, 46% of them completed 5 cycles of concurrent chemotherapy and 8.6% patients received neo-adjuvant chemotherapy. About 69% patients received brachytherapy with HDR Co-60 sources and 23% of patients received their brachytherapy treatment after 12 weeks of completion of EBRT. Conclusion: Lack of proper clinical evaluation and documentation, delay in referral and lack of implementation of a standard protocol for the treatment of carcinoma cervix are the major obstacles in our country. DOI: http://dx.doi.org/10.3329/dmcj.v1i2.15915 Delta Med Col J. Jul 2013;1(2):31-36

Cervical cancer patients’ preferences and use of various cancer information sources in South Korea

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 16073-16073
Author(s):  
H. Noh ◽  
M. Lee ◽  
Y. Yun ◽  
S. Park ◽  
D. Bae ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
South Korea ◽  
Cancer Patients ◽  
Information Sources ◽  
Age Groups ◽  
Cancer Center ◽  
Cancer Information ◽  
Age Group ◽  
Institutional Review ◽  
Personal Accounts

16073 Background: Accessing appropriate facts is important in enabling cancer patients cope with the disease. This study focused on the utilization and preferences of cancer information sources by cervical cancer patients in terms of ease in receiving and searching the available data. Methods: The study included 830 women over the age of 18 years treated for cervical cancer at six hospitals in South Korea between 1983 and 2004. All the participants provided written informed consent, and the Institutional Review Board of the National Cancer Center approved the protocol. A questionnaire addressed the patients’ use of and preferences for sources and forms of cancer information. Data were collected by mail. Results: Television and/or the radio were the the most frequently cited sources of cancer information by the middle and oldest age groups: 45–64 years (52.0%), =65 years (47.3%), while patients in the youngest age group (<45 years) used the Internet (38.8%). Booklets and/or pamphlets (24.0%) were the source of cancer information preferred by the youngest age group, while patients in the middle and oldest age groups preferred TV/radio: 45–64 years (35.7%) and =65 years (55.0%). Life notes and/or experiences (43.2%), that is, personal accounts, comprised the most easily understood form of information regardless of age group. Conclusions: Our findings indicate that cervical cancer patients’ utilization of and preferences for sources of cancer information vary according to patient age. Tailored educational materials that consider the users’ age and condition should be customized to best fit their specific preferences. No significant financial relationships to disclose.

The Burden of False-Positive Results in Analog and Digital Screening Mammography: Experience of the Nova Scotia Breast Screening Program

2014 ◽  
Vol 65 (4) ◽  
pp. 315-320 ◽  
Author(s):  
Jennifer I. Payne ◽  
Tetyana Martin ◽  
Judy S. Caines ◽  
Ryan Duggan
Keyword(s):  
False Positive ◽  
Screening Program ◽  
Task Force ◽  
Age Groups ◽  
Preventive Health Care ◽  
Screening Mammography ◽  
Age Group ◽  
Patients Âgés ◽  
Screening Performance ◽  
Screening Mammograms

Purpose The Canadian Task Force on Preventive Health Care released recommendations for breast cancer screening, in part, based on harms associated with screening. The purpose of this study was to describe the rate of false-positive (FP) screening mammograms and to describe the extent of the investigations after an FP. Methods A cohort was identified that consisted of all screening mammograms performed through the Screening Program (2000-2011) with patients ages 40-69 years at screening. Rates of FP screening mammograms were calculated as well as rates of further investigations required, including additional imaging, needle core biopsy, and surgery. Analyses were stratified by 10-year age group, screening status (first vs rescreen), and technology. Results A total of 608,088 screening mammograms were included. The FP rate varied by age group, and decreased with increasing age (digital, 40-49 years old, FP = 8.0%; 50-59 years old, FP = 6.3%; 60-69 years old, FP = 4.6%). The FP rate also varied by screening status (digital, first screen, FP = 12.0%; rescreen, FP = 5.6%), and this difference was consistent across age groups. The need for further investigation varied by age group, with invasive procedures being more heavily used as women age (digital, rescreen group, surgery: 40-49 years old, 1.1%; 50-59 years old 1.6%, 60-69 years old, 1.8%). Conclusions Both the FP screening mammogram rate and the degree to which further investigation was required varied by age group and screening status. Reporting on these rates should form part of the evaluation of screening performance.

scholarly journals Patterns of glioblastoma treatment and survival over a 16-years period: pooled data from the German Cancer Registries

2021 ◽  
Author(s):  
Ljupcho Efremov ◽  
Semaw Ferede Abera ◽  
Ahmed Bedir ◽  
Dirk Vordermark ◽  
Daniel Medenwald
Keyword(s):  
Proportional Hazards ◽  
Age Groups ◽  
Cancer Registries ◽  
International Classification Of Diseases ◽  
Cox Proportional Hazards ◽  
Treatment Modalities ◽  
Rank Test ◽  
Age Group ◽  
Term Survival ◽  
Younger Age

Abstract Introduction Glioblastoma multiforme (GBM) is a primary malignant brain tumour characterized by a very low long-term survival. The aim of this study was to analyse the distribution of treatment modalities and their effect on survival for GBM cases diagnosed in Germany between 1999 and 2014. Methods Cases were pooled from the German Cancer Registries with International Classification of Diseases for Oncology, third edition (ICD-O-3) codes for GBM or giant-cell GBM. Three periods, first (January 1999–December 2005), second (January 2006–December 2010) and a third period (January 2011–December 2014) were defined. Kaplan–Meier plots with long-rank test compared median overall survival (OS) between groups. Survival differences were assessed with Cox proportional-hazards models adjusted for available confounders. Results In total, 40,138 adult GBM cases were analysed, with a mean age at diagnosis 64.0 ± 12.4 years. GBM was more common in men (57.3%). The median OS was 10.0 (95% CI 9.0–10.0) months. There was an increase in 2-year survival, from 16.6% in the first to 19.3% in the third period. When stratified by age group, period and treatment modalities, there was an improved median OS after 2005 due to treatment advancements. Younger age, female sex, surgical resection, use of radiotherapy and chemotherapy, were independent factors associated with better survival. Conclusion The inclusion of temozolomide chemotherapy has considerably improved median OS in the older age groups but had a lesser effect in the younger age group of cases. The analysis showed survival improvements for each treatment option over time.

scholarly journals Cytomorphometric Analysis of Cervical Papanicolaou Smear for Females with Gynecological Clinical Complaints

2021 ◽  
Vol 11 (1) ◽  
pp. 46-49
Author(s):  
Sahar Osman ◽  
Ehab Elmadenah ◽  
Osman Elmahi ◽  
Mubarak Alkarsani ◽  
Lienda Eltayeb ◽  
...  
Keyword(s):  
Pap Smear ◽  
Screening Program ◽  
Age Groups ◽  
Pap Test ◽  
Optical Microscope ◽  
Pap Smears ◽  
Age Group ◽  
Limited Information ◽  
Gynecological Diseases ◽  
A Prospective Study

Background: Limited information is provided on the quantitative cytomorphometric study of the cervical Pap test. The cervical Pap test is an important screening program for cervical cancer. A quantitative cytomorphometric examination of cervical Pap is used to accurately identify precancerous and cancerous lesions early and to reduce the occurrence and avoidance of invasive cancer. This study was aimed to assess the cytomorphological parameters (nuclear diameter [ND], cytoplasm diameter [CD], and nuclear-to-cytoplasmic ratio [N/C ratio]) of squamous epithelial cells from a cervical Pap smear. Methods and Results: A prospective study was performed on 142 consecutive cervical Pap smears from women with gynecological clinical complaints. The ND and CD were determined by the Optika optical microscope camera using a digitizer cursor in both axes. The final images were taken with an X40 magnification. The ND, CD, and the N/C ratio were then measured and expressed in micrometers. The women were classified into 5 age groups: 5(3.5%) in the age group of <19 years, 46(32%) in the 20-29 group, 67(47.2%) in the 30-39 group, 23(16.2%) in the 40-49 group, and 1(0.7%) woman was over age 50. There were no significant differences in the N/C ratio of superficial cells between age groups. The ND, CD, and the N/C ratio were significantly higher in women with clinical complaints than in women without clinical complaints Conclusion: Cytomorphometic analysis might assist in the identification of cellular alterations due to gynecological diseases and increase the sensitivity and accuracy of the Pap smear technique.

scholarly journals Profile of PAP smears done in a tertiary centre in North Kerala

2018 ◽  
Vol 5 (5) ◽  
pp. 1974 ◽  
Author(s):  
Enid Elizabeth Thomas ◽  
Jayasree Anandabhavan Kumaran
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Precancerous Lesions ◽  
Age Groups ◽  
Cancer Control ◽  
Target Population ◽  
Pap Smears ◽  
Age Group ◽  
Cervical Smears

Background: In India, cervical cancer is the second most common cancer among women. WHO sponsored expert group meeting on “Strategies for Cervical cancer Control” recommends women of 30-59 years as target group for cervical cancer screening in India. Statistics show us that routine cervical cancer screening is not happening in India.Methods: This is a retrospective, descriptive, record based study done in a private medical college in Northern Kerala to study the profile of PAP smears during the years, 2014 and 2015 and to find out the appropriateness of the recommendations for age for cervical cancer screening. The data regarding cervical smears were analyzed using Epi info software.Results: A total of 3059 cervical smears were analyzed retrospectively. The age group of the study population ranged from 21 years to 93 years with the mean age of 46.3942±13.7 SD. Of all the smears, 2993 (97.84%) were Negative for intraepithelial lesion or malignancy (NILM). A total of 66 smears (2.15%) showed epithelial abnormality. All precancerous lesions, LSIL (29.03%), HSIL (37.04%) and Atypia (37.5%) were most commonly found in the age group of 61-70 years.Conclusions: The incidence of epithelial abnormality is found increasingly in older age groups. Limiting the target population for screening to 30-59 years, will result in missing out of many cases with precancerous lesions which in turn may fail our attempts in reducing the burden of cervical cancer. So a higher age group as target population needs to be set.

EFFECTIVENESS OF CERVICAL CANCER SCREENING IN THE CITY MUNICIPAL ENTERPRISE ON THE RIGHT OF ECONOMIC MANAGEMENT CITY POLYCLINIC №5 OF ALMATY»

Vestnik ◽  
2021 ◽  
pp. 7-15
Author(s):  
Д.Ж. Максутова ◽  
А.Э. Миреева ◽  
Д.О. Карибаева ◽  
Т. Асан ◽  
У. Балтабаева ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Early Detection ◽  
Screening Program ◽  
Age Group ◽  
Economic Management ◽  
The Right ◽  
The City ◽  
Analyze Data

Одной из задач нашего исследования был анализ данных скрининговой программы по раннему выявлению раковых и предраковых заболеваний шейки матки в ГП №5, который показал, что процент охвата скрининговой программой целевой группы соответствует государственной программе. Качество проведения скрининговой программы в ГП№5 значительно улучшилось, снизился процент неинформативного материала. Большинство женщин, которые умерли от рака шейки матки, относятся к возрастной группе 80 лет и старше. One of the objectives of our study was to analyze data from the screening program for early detection of cervical cancer and precancerous diseases in GP №5, which showed that the percentage of coverage of the target group's screening program corresponds to the state program. The quality of the screening program in GP№5 has significantly improved, and the percentage of non-informative material has decreased. Most women who have died from cervical cancer are in the age group of 80 or older.

Incidence patterns of early onset colon cancer by race and stage in the US.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e18168-e18168
Author(s):  
Nishi Shah ◽  
Ana Acuna-Villaorduna ◽  
Sanjay Goel
Keyword(s):  
Colon Cancer ◽  
American Indians ◽  
Early Onset ◽  
Age Groups ◽  
Young Patients ◽  
Cancer Registries ◽  
Age Group ◽  
Annual Percent Change ◽  
Percent Change ◽  
The Us

e18168 Background: Several studies show that incidence of colorectal cancer is increasing among young individuals. However, information on incidence of early onset colon cancer by race and stage is lacking. Methods: We analyzed incidence of colon cancer using National Program of Cancer Registries database which covers 99% of the US population. We identified colon cancer using ICD-O-3 code 8000-9049, 9056-9139, 9141-9589, along with the variable for site from cecum to sigmoid colon for years 2001 to 2015. SEER*Stat was used to calculate age-adjusted rates, trends and annual percent change. Results: Age adjusted incidence rate for colon is 31.2 cases per 100,000 among the entire population. Incidence in the age group of 15-39 years, 40-49 years, 50-59 years, 60-69 years, 70-79 years, 80+ years is 2.4, 14.3, 39.8, 86, 165.8, 232.3 per 100,000 respectively. The distribution of colon cancer by race for age groups is listed in table. When evaluating the incidence trend in each race for early onset colon cancer, the trend shows a rise in whites for both age groups (Annual Percent Change [APC] 3.4%, 1.5% for 15-39 years, 40-49 years of age respectively, p < 0.05). The trend in blacks on the other hand shows a rise of 1.2% (p < 0.05) in 15-39 years of age and a small but statistically significant decrease in incidence in 40-49 years of 0.5% (p < 0.05). In Asian Pacific Islanders (API) and American-Indians or Alaskan Natives (AI), the trend is not significant for either age groups. In the age groups above 50 years, the trend shows a decrease in incidence of colon cancer in all races. The rise in incidence for colon cancer in 15-39 years age group appears higher in localized disease as compared to metastatic disease (6.5% vs 2.8% for localized vs distant site of disease). Conclusions: This study highlights differences in incidence of early onset colon cancer among young patients by race and stage. Although there have been more cases of early onset colon cancers in blacks, the rise in incidence is higher in whites. With colonoscopy, there has been decrease in incidence of colon cancer for patients > 50 years for all races and stages. [Table: see text]

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