scholarly journals Analysis on the Incidence, Staging and Treatment of Carcinoma Cervix at Delta Medical College and Hospital of Bangladesh

2013 ◽  
Vol 1 (2) ◽  
pp. 31-36
Author(s):  
Parvin A Banu ◽  
Naheed Rukhsana ◽  
Jebunnessa Yasmin ◽  
Lutfun Nahar ◽  
Sadiqur R Malik

Background: Cervical cancer remains the most common cancer among women in this part of the world. Bangladesh has the highest level of incidence and mortality rates due to cervical cancer among women. Cervical cancer is a preventable disease by screening and treatment of pre-invasive condition. Unfortunately, there is no effective screening program in Bangladesh. Objective: The objective was to analyze the clinico-pathologic characteristics and, subsequently the therapy delivered to the patients. Materials and method: This cross sectional study was done from January to December 2011 in oncology division of Delta Medical College and Hospital, Dhaka, Bangladesh. During this period a total of 2264 female carcinoma patients were registered. Out of them 523 patients were with the diagnosis of carcinoma of cervix. Evaluation and characterization of patients with carcinoma cervix were done according to the age group, clinical stages and surgical status. External beam radiotherapy (EBRT) and doses, brachytherapy doses and fractions, time interval between EBRT and brachytherapy, neo-adjuvant and concurrent chemotherapy status were the factors taken into consideration for the analysis of treatment of these patients. Results: The study revealed that the incidence of carcinoma cervix was 23% and highest incidence was between 40-50 years of age group, most of the patients were in Stage IIB (34%) and IIIB (28%) and 31% with unknown stage. About 44% patients were referred postoperatively and most of them with unknown stage. Almost 90% patients received EBRT, 24% patients received concurrent chemo-radiation, 46% of them completed 5 cycles of concurrent chemotherapy and 8.6% patients received neo-adjuvant chemotherapy. About 69% patients received brachytherapy with HDR Co-60 sources and 23% of patients received their brachytherapy treatment after 12 weeks of completion of EBRT. Conclusion: Lack of proper clinical evaluation and documentation, delay in referral and lack of implementation of a standard protocol for the treatment of carcinoma cervix are the major obstacles in our country. DOI: http://dx.doi.org/10.3329/dmcj.v1i2.15915 Delta Med Col J. Jul 2013;1(2):31-36

2015 ◽  
Vol 14 (2) ◽  
pp. 57-60
Author(s):  
Fahmida Shirin Papri ◽  
Zubaida Khanam ◽  
Fahmida Islam ◽  
Md Monjurul Hakim

Cervical cancer is one of the leading causes of morbidity and mortality amongst the gynaecological cancer in Bangladesh.This study was carried out to assess the knowledge of cervical cancer, awareness of the women towards the cervical cancer screening program and its vaccination in Bangladesh. A cross- sectional interview based study was conducted using a self administered questionnaire between January 1 ,2013 and June 31, 2013 on 508 respondents. Convenience sampling was applied among the women attending at Gynae Out Patient Department (GOPD) of Chittagong Medical College Hospital for VIA (Visual Inspection with Acetic Acid) test. Of the 508 respondents only 211(41.54%) told that they had idea about cervical cancer, while only 114 (22.44%) knew that VIA is the screening test for cervical cancer.A total of 390 (76.77%) respondents did not know any cause of cervical cancer.Most of the respondents (80%) came for VIA due to doctor’s advice.After doing VIA among 229 respondents, 149 (65.07%) told that they had been counseled for the next follow - up by the health professionals and 118 (51.52%) were ready for routine periodic screening.Majority (85.88%) of the respondents were absolutely ignorant about the vaccine of cervical cancer. Age and marital status did not influence their knowledge but the level of education and occupation was found to positively influence their knowledge of cervical cancer and their acceptance of the screening test.This study highlights that majority of women in Bangladesh are not adequately equipped with knowledge concerning cervical cancer. Adequate health information and counseling on cervical cancer and regular screening test need to be emphasized in our country.Chatt Maa Shi Hosp Med Coll J; Vol.14 (2); Jul 2015; Page 57-60


2012 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
Sushmita Roy ◽  
S.M. Shamsuzzaman ◽  
K.Z. Mamun

Rotavirus is one of the leading causes of pediatric diarrhea globally. Accurate and rapid diagnosis of Rotavirus diarrhea should reduce unnecessary use of antibiotics and ultimately reduce drug resistance. Study was designed for rapid diagnosis of Rotavirus antigen in stool sample by ICT (Immunochromatographic test) as well as to observe the seasonal variation of rotavirus infection. This cross sectional study was carried out in the department of Microbiology, Dhaka Medical College from January 2011 to December 2011. Eighty stool samples were collected from Dhaka Shishu Hospital and Dhaka Medical College Hospital. All samples were tested for rotavirus antigen by ICT. Among 80 patients, 42 (52.5%) samples were positive for rotavirus antigen. Among these 42 positive samples, 30 (71.43%) were from 0-12 months of age group, 10 (23.81%) from 13 to 24 months of age group and rest 2 (4.76%) from 25 to 36 months of age group. Rotavirus Ag was detected in stool samples from January to April and another peak episode from October to December. Considering the importance of Rotavirus associated diarrhea, rapid detection of Rotavirus infection in human is substantially needed and should be routinely practiced.DOI: http://dx.doi.org/10.3329/bjmm.v6i1.19354 Bangladesh J Med Microbiol 2012; 06(01): 11-13


1970 ◽  
Vol 40 (1) ◽  
pp. 18-21 ◽  
Author(s):  
MN Hossain ◽  
Z Rahman ◽  
S Akhter

A cross sectional study was carried out at the department of Forensic Medicine in Dhaka Medical College during the period of January 2008 to December 2009. Data were collected from 3rd copy of the post mortem reports which were preserved in the department of Forensic Medicine with the verbal consent of the doctors who performed autopsy report. During this period total 5114 autopsies were conducted. Out of this 970 cases (19%) were suicidal in nature. It was noticed that all suicidal deaths occurred from 10 years to all age group respectively, but top amongst age group of suicidal deaths occurred in between 21 to 30 years of people. Suicidal deaths are more common in female than male. Suicidal deaths due to hanging is highest, next common causes of death due to organophosphorus compund poisoning. Suicidal deaths by hanging is more in female than male but in poisoning cases male are more lvictimised than female. Objectives of our study are to see the occurrence and methods of suicidal death. DOI: http://dx.doi.org/10.3329/bmj.v40i1.9957 BMJ 2011; 40(1): 18-21


2013 ◽  
Vol 12 (3) ◽  
pp. 44-48
Author(s):  
Joyabrata Das ◽  
Subash Majumdar ◽  
Subrata Das ◽  
Saiem Nurul Anwar ◽  
Hossain Ahmed ◽  
...  

Background: The liver is the organ most subjected to the development of abscesses and made up 48 % of all visceral abscesses' and 7% of all intra abdominal abscesses. Liver abscess should be suspected when there is a combination of fever, leucocytosis, constitutional symptoms, and pain in the right upper quadrant, and tenderness over the liver or right lower rib cage. The liver is affected by a number of local and disseminated infections; their frequency and types vary considerably around the world. Parasitic disorders are more prevalent in developing countries. Methods: It was a cross-sectional descriptive study. The cases were taken from the admitted patients of Medicine unit of SMCH, Chittagong. The study was conducted over a period of one year with a sample size of 50 patients and sample was taken by purposive sampling. Results: Among 50 patients 40 (80%) were diagnosed as ALA and 10 (20%) were diagnosed as PLA. ALA cases are common in 21-30 years age group & PLA cases are more common in >50 years of age group. Majority of the cases were from rural area. Common clinical features were fever, abdominal pain, nausea and tender hepatomegaly. Diarrhea was present on admission in 7 (15.9%) patients of ALA. Anaemia was common in both but polymorphonuclear leucocytosis was moderate to severe in PLA. Microscopic examination of stool samples for E. Histolytica trophozoites was positive in 3 (7.5%) cases and cysts in 4(10%) cases. Nine patients had right sided pleural effusion. Conclusions: Clinical features are common in both ALA and PLA. Liver abscesses are more common in men and more prevalent in rural areas. ALA more commonly occurs in 21-30 years age group but can occur at any age. Pyogenic abscess is more common in older age group (>50 years) and E. Coli is the commonest organism. Chattagram Maa-O-Shishu Hospital Medical College Journal Volume 12, Issue 3, September 2013: 44-48


2020 ◽  
Vol 14 (2) ◽  
pp. 97-100
Author(s):  
Md Abdul Wahab ◽  
Md Mustafizur Rahman ◽  
Md Abdur Razzak ◽  
Md Habibur Rahman ◽  
Mimi Parvin ◽  
...  

Introduction: Metabolic syndrome (MetS) is a multifaceted syndrome comprises a cluster of metabolic abnormalities including hypertension, central obesity, insulin resistance, dyslipidemia, and is strongly associated with developing diabetes mellitus and cardiovascular diseases. Prevalence of MetS differs in different ethnic population by using different definition. Objectives: To determine the prevalence of the MetS and its component risk factors among Border Guard Bangladesh (BGB) personnel working in Chattagram Hill Tract (CHT). Materials & Methods: This descriptive cross-sectional study was conducted from October 2016 to February 2018 among 1455 male BGB personnel aged between 40 to 59 years and working in CHT of Bangladesh. Study subjects were selected at BGB hospital, Guimara, Khagrachari. The new International Diabetes Federation (IDF) guidelines were used to identify MetS. Detail history, clinical examination, anthropometry and blood pressure (BP) were measured and fasting plasma glucose (FPG) and lipid profile were assessed. Results: Among the 1455 respondents’ BMI, waist circumference, systolic and diastolic BP were found more than normal in 34.1, 37.7, 16.4% and 12.3% respectively. Biochemical parameters including FPG, TC, TG, and LDL-C was raised in 28.7%, 49.8%, 52.2% and 37.7% of respondents respectively. HDL-C was found decreased in 26.9% respondents. Age wise prevalence of MetS for age group 40-44, 45-49, 50-54 and 55- 59 years were found 21.3%, 21.7%, 24.1% and 26.1% of the respondents respectively. The overall prevalence of MetS was found 22.4%. Conclusion: The prevalence of the MetS in BGB personnel was found 22.4%. Appropriate measure should be taken to lower the MetS cases. Journal of Armed Forces Medical College Bangladesh Vol.14 (2) 2018: 97-100


Author(s):  
Susmita Chaudhuri ◽  
Rekha Dutt ◽  
Shweta Goswami ◽  
Joydeb Roychowdhury

Background: Cervical cancer is a leading cause of morbidity and mortality in women especially India. The mainstay of prevention rests on early detection of cases through screening. So, this study aims to determine the knowledge of cervical cancer screening, Human papilloma virus & its vaccination status. Methods: This was an observational study of cross-sectional design conducted among the adult reproductive aged women (18-45 years) visiting Gynaecology OPD at ESI-PGIMSR and ESIC Medical College and Hospital, Joka. A pre-designed and pre-tested interview schedule was prepared. Face to face interview was conducted in local language. Data was compiled & computed in SPSS software version 20. Results: Total respondents were 97. Majority of the respondents (62.9%) belong to the age group of 21-30 years. 8 in 10 participants follow Hinduism. Almost equal percentages of participants were from urban & rural areas (51.5% & 48.5% respectively). 6 in 10 participants had heard about cervical cancer. Majority of the respondents (55%) mentioned friends & family as a source of information. 48.3% of the respondents knew poor genital hygiene as a predisposing risk factor for cervical cancer. Very few knew about other factors like multiple sexual partner (20%), early marriage (33.3%), young age (20%), repeated childbirth (35%), OCP usage (26.7%) as risk factors for cervical cancer. Only one participant had undergone screening test for cervical cancer (1.7%). 46.7% of the respondents were aware about association of HPV infection with cervical cancer. But none of the participants had received vaccine against cervical cancer & they cited lack of awareness as a reason for not receiving the vaccine. Conclusions: A well-designed health education program focusing on effective multipronged IEC strategies utilizing pictorials, audio-visual and personal communication on cervical cancer could yield beneficial results. 


2016 ◽  
Vol 5 (2) ◽  
pp. 26-28
Author(s):  
Zubaida Gulshan Ara ◽  
ASM Shafiqul Islam ◽  
Umme Kulsum Sharmin Zaman ◽  
Anjuman Ara ◽  
Reeva Aireen Busreea

This cross sectional descriptive study was done to see the length of the cervix in Bangladeshi cadaver to find out the anatomical variation and to compare it with other study findings. 60 post mortem specimens containing female genital organs particularly uterine cervix were collected by purposive sampling technique from cadavers of different age groups. All the collected specimens were fixed in 10% formalin solution. This study was carried out in the department of Anatomy, Mymensingh Medical College from July 2006 to June 2007. Both gross and fine dissections were performed to measure the length of the uterine cervix. We compare our study findings with that of the references. Maximum mean length of the cervix was found in the 13-45 years age group. It was 2.89 cm. CBMJ 2016 July: Vol. 05 No. 02 P: 26-28


Author(s):  
Santosh D. Patil ◽  
Ravindranath A. Bhovi

Background: Nutritional anaemia is defined as a condition in which the haemoglobin content of the blood is lower than normal as a result of deficiency of one or more essential nutrients. Anaemia is the late manifestation of deficiency of nutrient(s) needed for haemoglobin synthesis. The prevalence of anaemia in developing countries is estimated to be 43% and that of developed countries is 9%. Anaemia is estimated to contribute to more than 115000 maternal deaths and 591000 prenatal deaths globally per year. The objectives of the present study were to determine the prevalence of anaemia among the pregnant women and lactating mothers and to explore the associated factors with anaemia.Methods: A cross sectional study was conducted among pregnant and lactating women in Ukkali a rural field practice area Shri B. M. Patil Medical College, Vijayapur. Criteria for inclusion were pregnant women- current pregnancy of more than 6 months and lactating mother with child aged up to 6 months of age. Estimation of haemoglobin was carried by standard Sahlis pipette method. Anaemia was classified according to WHO grading criteria.Results: The maximum number of pregnant women (85.71%) in the age group of 35-49 years was anaemic followed by those who were in the age group of 20-34 years (61.54%). Prevalence of anaemia was 72 % in women of less than 20 years, whereas it was as high as 80% among lactating women of 35-49 years age group.Conclusions: Anaemia continues to be a problem with the existing health care resources. Socio-economic status, literacy of women and awareness related to health concerns are the major determinants that contribute to the problem of anaemia.


2021 ◽  
pp. 40-42
Author(s):  
Arpan Jana ◽  
Pabitra Das ◽  
Poulami Gupta ◽  
Phalguni Gupta

Background: Concurrent chemo-radiation is the standard treatment worldwide for locally advanced squamous Cell carcinoma cervix. However, conventional chemo-radiotherapy is also associated with unacceptable local and systemic failure rates for locally advanced disease. Biologically squamous cell carcinoma of head- neck cancer and cervical cancer behaves quite similarly in response to radiotherapy. So, it can be expected that, altered fractionation can increase the local control in case of squamous cell carcinoma cervix than conventional radiotherapy. There is no randomised control trial for carcinoma cervix till date, which compares conventional chemo-radiation with hypo-fractionated chemo-radiation. Aims And Objectives: The present study was planned to compare local disease control and acute toxicity of conventional chemo-radiation with hypo-fractionated chemo-radiation in locally advanced carcinoma cervix. Materials And Methods: In Conventional Chemo-radiation Arm A patients (n=30) received external beam radiotherapy 50 Gy in 25 fractions in 5 weeks accompanied by weekly intravenous Cisplatin 40mg/m2 followed by intracavitary brachytherapy 7 Gy per fraction once in a week for 3 weeks. The second group of hypo-fractionated Arm B received external beam radiotherapy 45 Gy in 20 fractions in 4 weeks accompanied by weekly intravenous Cisplatin 40mg/m2 followed by intracavitary brachytherapy 9 Gy per fraction once in a week for 2 weeks. Results: Grade II diarrhea were seen more in Arm B 17 (56.66%) compare to Arm A 12(40%) and grade III diarrhea was seen 4 (3.33%) in Arm B and 2(6.66%) in Arm A. At 2 months and 6 months after completion of treatment Complete response were 25 (83.4%) in Arm A compare to 22 (73.3%) in Arm B and 20 (74.1%) in Arm A and 18 (72%) in Arm B respectively. Conclusion: Hypo-fractioned radiotherapy may be used as an alternate protocol for treatment of locally advanced carcinoma cervix with acceptable toxicities.


2015 ◽  
Vol 9 (2) ◽  
pp. 76-79 ◽  
Author(s):  
Mushtaq Ahmad ◽  
Farial Naima Rahman ◽  
Md Mozaharul Islam ◽  
Md Rakib Uddin Majumder

Self destruction or suicide by pesticide poisoning is a burning problem of Bangladesh. Rapid development in science and rapid growth in agricultural activities has led to the increase in the incidences of poisoning. The objective of this study was to find out the incidences and pattern of poisoning in an urban area, different aspects of poisoning along with demographic pattern, social factors related and other related perimeter, and modality to prevent loss of precious life due to poisoning. This retrospective cross sectional study was conducted among victims of poisoning at Dhaka Medical College, Dhaka Morgue during the period of January 2008-December 2009. Specific identification of poisons was made from Chemical Examiner's report. All the data were later on analyzed. A total of 5114 medico legal post mortems were performed during this study period. Among these 300 (5.87%) cases were suspected poisoning. Out of these cases specific poisons were identified in 131 (43.66%) cases. Among the detected poisoning cases OPC was the commonest agent 103 (78.63%) followed by alcohol/rectified spirit 12 (9.16%) and barbiturate 7 (5.34%). No poison was detected (Negative results) in 116 (38.66%) cases and no reports from chemical examiner were received in 53 (17.66%) cases during the study period. Out of 300 victims 174 (58%) were male and 126 (42%) were female. Highest incidence of poisoning was observed in 21-30 years age group 117 (39%) followed by age group of 31-40 years 84 (28%). Most of the victims were agricultural workers/ farmers 108 (36%) followed by housewives 51 (17%). Among the study subjects 178 (59.33%) were illiterate and 198 (66%) were married. Considering manner of death 274 (91.33%) victims committed suicide by poisoning and rests 26 (8.67%) were due to accidental poisoning. To reduce poisoning cases proper emphasis should be given for safe use of pesticides and consciousness should be created among the population about poisonous compounds. Detail study regarding death due to poisoning is required to be carried out in this country.Faridpur Med. Coll. J. 2014;9(2): 76-79


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