scholarly journals Detection of a extramedullary plasmocytoma in the sphenoid sinuses

2019 ◽  
Author(s):  
S Bär ◽  
M Kemper ◽  
T Zahnert
Keyword(s):  
Extramedullary Plasmocytoma ◽  
Sphenoid Sinuses

scholarly journals Clinical and Biological Characteristics of Medullary and Extramedullary Plasma Cell Dyscrasias

Biology ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 629
Author(s):  
Snjezana Janjetovic ◽  
Philipp Lohneis ◽  
Axel Nogai ◽  
Derya Balci ◽  
Leo Rasche ◽  
...  
Keyword(s):  
Plasma Cell ◽  
Molecular Mechanisms ◽  
Biological Characteristics ◽  
Surface Glycoprotein ◽  
Cell Surface Glycoprotein ◽  
Similar Frequency ◽  
Cytogenetic Aberrations ◽  
A Cell ◽  
Plasma Cell Dyscrasias ◽  
Extramedullary Plasmocytoma

Background: Extramedullary plasma cell (PC) disorders may occur as extramedullary disease in multiple myeloma (MM-EMD) or as primary extramedullary plasmocytoma (pEMP)/solitary osseous plasmocytoma (SOP). In this study, we aimed to obtain insights into the molecular mechanisms of extramedullary spread of clonal PC. Methods: Clinical and biological characteristics of 87 patients with MM-EMD (n = 49), pEMP/SOP (n = 20) and classical MM (n = 18) were analyzed by using immunohistochemistry (CXCR4, CD31, CD44 and CD81 staining) and cytoplasmic immunoglobulin staining combined with fluorescence in situ hybridization (cIg-FISH). Results: High expression of CD44, a cell-surface glycoprotein involved in cell-cell interactions, was significantly enriched in MM-EMD (90%) vs. pEMP/SOP (27%) or classical MM (33%) (p < 0.001). In addition, 1q21 amplification by clonal PC occurred at a similar frequency of MM-EMD (33%), pEMP/SOP (57%) and classical MM (44%). Conversely, del(17p13), t(4;14) and t(14;16) were completely absent in pEMP/SOP. Besides this, 1q21 amplification was identified in 64% of not paraskeletal samples from MM-EMD or pEMP compared to 9% of SOP or paraskeletal MM-EMD/pEMP and 44% of classical MM samples, respectively (p = 0.02). Conclusion: Expression of molecules involved in homing and cytogenetic aberrations differ between MM with or without EMD and pEMP/SOP.

Utility of current sialendoscopes in the sinonasal cavity

2015 ◽  
Vol 129 (9) ◽  
pp. 870-873
Author(s):  
C R Kieliszak ◽  
T R Khoury ◽  
A Singh ◽  
A S Joshi
Keyword(s):  
Drug Delivery ◽  
Minimally Invasive ◽  
Paranasal Sinuses ◽  
Sphenoid Sinus ◽  
Mucosal Biopsy ◽  
Before And After ◽  
Invasive Method ◽  
Cannulation Success ◽  
Cadaveric Model ◽  
Sphenoid Sinuses

AbstractObjectives:This study assessed the utility of current sialendoscopes in the paranasal sinuses in a cadaveric model and evaluated novel uses for sialendoscopes.Methods:Currently available sialendoscopes were used for visualisation and performing interventions in the paranasal sinuses. Ten cadaver heads were studied before and after dissection. Outcomes included ostia identification, sinus cannulation, success of mucosal biopsy collection and image clarity.Results:Marchal and Erlangen sialendoscopes were found to be effective for both visualising and cannulating the sphenoid sinuses before and after dissection. Both types demonstrated poor maxillary ostia visualisation without dissection, but did allow treatment after antrostomy. Larger diameter sialendoscopes were associated with the lowest image distortion during maxillary ostia assessment. Mucosal biopsy collection within the sphenoid sinus, but not in the maxillary sinus, was possible before dissection.Conclusion:Sialendoscopes can be used for visualisation and performing interventions in the sinonasal cavity, but their utility is mainly limited to the sphenoid sinus. They may be considered a minimally invasive method for drug delivery and/or biopsy collection in the post-operative setting for all sinuses. Design improvements are suggested.

Obliteration of maxillary and sphenoid sinuses in Gaucher's disease.

1997 ◽  
Vol 70 (833) ◽  
pp. 533-535 ◽  
Author(s):  
N Karabulut ◽  
A Ahmetoglu ◽  
M Ariyürek ◽  
C Erol ◽  
F Gürakan
Keyword(s):  
Gaucher's Disease ◽  
Gaucher’S Disease ◽  
Sphenoid Sinuses

Solitary Ovarian Plasmocytoma: A Rare localization of Extramedullary Plasmocytoma. A Case Report

2021 ◽  
Vol 4 (5) ◽  
pp. 01-04
Author(s):  
Salma Fares ◽  
Adil Taoufik ◽  
Aissam Maataoui ◽  
Kaoutar Sokori ◽  
Ouadie Qamouss
Keyword(s):  
Plasma Cells ◽  
Female Genital Tract ◽  
Malignant Neoplasm ◽  
Solitary Plasmacytoma ◽  
Adequate Treatment ◽  
Complete Surgical Resection ◽  
Plasma Cell Dyscrasias ◽  
Extramedullary Plasmocytoma ◽  
Work Up

Background: Solitary plasmacytoma is a rare malignant neoplasm of plasma cells accounting 5-10% of all plasma cell dyscrasias with extramedullary plasmocytoma in 3- 5%. Their localization in the female genital tract is quite rare, either as solitary plasmacytomas or as part of a disseminated MM. Solitary ovarian plasmocytoma is extremely rare. Case: A 52-year-old woman, presented presented postmenopausal recurring episodes of metrorrhagia with left ovarian mass. She was diagnosed with solitary ovarianplasmocytoma without systemicdisease. The patient underwent complete surgery resection and a full work up to rule out multiple myeloma that objectived a small serum monoclonal protein that had resolved postoperatively. At 17 months of follow-up, the patient is still alive and doing well with no signs of recurrence or progression to mutliple myeloma. Although rare, solitary plasmacytoma of the ovary can occur without any overt symptoms or laboratory abnormalities tests and require prompt and adequate treatment and rigorous monitoring due to their ability to relapse or progress to MM. Complete surgical resection followed by activesurveillance is appropriate.

Endoscopic anatomy of the sphenoid sinus

1999 ◽  
Vol 113 (2) ◽  
pp. 122-126 ◽  
Author(s):  
Samy Elwany ◽  
Ibraheim Elsaeid ◽  
Hossam Thabet
Keyword(s):  
Optic Nerve ◽  
Carotid Artery ◽  
Sphenoid Sinus ◽  
Sella Turcica ◽  
Clinical Importance ◽  
Sinus Surgery ◽  
Endoscopic Anatomy ◽  
Relationship Of ◽  
The Relationship ◽  
Sphenoid Sinuses

AbstractThe anatomy of the sphenoid sinus, as it relates to endoscopic sinus surgery, was studied in 93 cadaver heads (186 sphenoid sinuses) using endoscopic dissections as well as sagittal sections. The relationship of the sphenoid sinuses to the carotid artery, optic nerve, floor of sella turcica, as well as other important structures, were verified and discussed. The recesses of the sinus as well as its ostium and accessory septa and crests were described and their clinical importance was discussed. Pertinent measurements were included wherever appropriate.

EVALUATION OF VARIATIONS IN SPHENOID SINUS PNEUMATIZATION USING MULTIDETECTOR COMPUTED TOMOGRAPHY IN PATIENTS ATTENDING TERTIARY CARE HOSPITAL, VISAKHAPATNAM

2021 ◽  
pp. 62-65
Author(s):  
Sonica Sharma ◽  
Bhamidipaty Kanaka Durgaprasad ◽  
Payala Vijayalakshmi
Keyword(s):  
Computed Tomography ◽  
Paranasal Sinuses ◽  
Sphenoid Sinus ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Ct Images ◽  
Care Hospital ◽  
Anterior Clinoid Process ◽  
Anterior Extension ◽  
Sphenoid Sinuses

BACKGROUND: The purpose of our study was to assess the prevalence of different patterns of pneumatization in the sphenoid sinuses as detected on the computed tomography (CT) images of paranasal sinuses of the patients presenting with various pathologies. This is a retrospective radiological study of CT im MATERIALS AND METHODS: ages of paranasal sinuses, done at Radio diagnosis department of a Tertiary care hospital. The study comprised CT images of 500 patients in the age range of 18-75years who were referred for CT scan of paranasal sinuses for various pathologies between the period of July 2018 and July 2019. All images of paranasal sinuses had been acquired following a standardized protocol in axial plane. Their reconstructed images in axial, coronal and sagittal planes were evaluated, using Osirix software, for the extent and different patterns of sphenoid sinus pneumatization. The Images of sphenoid sinuses were assessed for the posterior, lateral and anterior extension of their pneumatization The sphenoid sinuses pneumatization patterns in the RESULTS: descending order of prevalence were complete sellar (75.0%), incomplete sellar (22.6%), presellar (2.4%) and conchal (0%). The clival extensions was seen in 75% of patients and lateral extension sides in 49.1% patients. Lateral recesses as assessed on coronal images was seen in 49.1 % of cases with the prevalence in descending order being extension into pterygoid process 59.8 %, greater wing of sphenoid 9.2 %, full lateral 41% and lesser wing (anterior clinoid process) 19.3%. The pure forms were relatively less common and combined forms being more common. A preoperative review of the sphenoid anatomy should allow for safer endo

The Functional State Of The Mucous Membrane Of The Nasal Cavity And Paranasal Sinuses After Radical And Minimally Invasive Surgical Interventions

2021 ◽  
Vol 03 (01) ◽  
pp. 31-40
Author(s):  
Mukhammadbobur Makhsitaliev ◽  
◽  
Jamolbek Djuraev ◽  
Shokhimardon Khodjanov ◽  
Abdurasul Botirov ◽  
...  
Keyword(s):  
Paranasal Sinuses ◽  
Adult Population ◽  
Annual Increase ◽  
Surgical Interventions ◽  
Minimally Invasive Surgical ◽  
Priority Task ◽  
Nose And Paranasal Sinuses ◽  
A Priority ◽  
Ethmoid Labyrinth ◽  
Sphenoid Sinuses

Improving the effectiveness of treatment of chronic rhinosinusitis (CRS) is a priority task of modern otorhinolaryngology, not only domestic, but also foreign. This interest in the problem is due to the widespread prevalence of this pathology. In different countries, the criteria for accounting for the incidence, algorithms for the diagnosis and treatment of rhinosinusitis differ significantly, and for CRS these differences are more pronounced than for acute. A retrospective analysis of the structure and prevalence of ENT diseases according to inpatient observations for 5 years showed that chronic diseases of the nose and paranasal sinuses (SNP) occupied a priority place among hospitalized patients (45.8 ± 0.9% and 55.5 ± 1,0%). In the structure of the main diseases of SNP, the largest share in the adult population is occupied by inflammation of the maxillary sinus (HPP), in which there is an annual increase in the incidence of 1-1.5%, the second most frequent is inflammation of the ethmoid labyrinth cells, then the frontal and sphenoid sinuses.

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