scholarly journals Fat Grafting for Hand Rejuvenation

2020 ◽  
Vol 34 (01) ◽  
pp. 047-052 ◽  
Author(s):  
Christopher J. Conlon ◽  
Amjed Abu-Ghname ◽  
Matthew J. Davis ◽  
Kausar Ali ◽  
Sebastian J. Winocour ◽  
...  

AbstractThe hands are one of the most visible parts of the body, and prominent dorsal veins and extensor tendons are the most readily recognized signs of the aging process. Fat grafting has been demonstrated to be a safe and effective method of hand rejuvenation by restoration of subcutaneous fat. Despite some variability in the technical approach, fat grafting techniques are consistent in their use of low-pressure injection with standard cannula sizes, small aliquots of graft, and a total volume of graft greater than or equal to 15 mL per hand. While distribution of the fat is an area of debate and a topic of active research, published studies have shown high patient satisfaction rates, suggesting that perhaps the restoration of volume alone is paramount. In this article, we will review the applications of fat grafting to the hand, focusing primarily on its role in hand rejuvenation.

2021 ◽  
pp. 074880682110247
Author(s):  
Paul von Waechter-Gniadek ◽  
Thomas Kündig ◽  
Pål Johansen ◽  
Roland Boeni

In high-definition liposculpture (HDL), the body is shaped in such a way that an athletic appearance and a defined, contoured look is created. Typical areas in the male patient include arms, pectoralis region, the area over the serratus muscle, lower back, as well as medial and lateral abdomen. This procedure is sometimes combined with fat grafting to areas over the deltoid muscle and/or pectorals. The objective was to evaluate the safety and satisfaction of HDL in a large series of patients using reciprocating power-assisted liposuction under local anesthesia. In this bicenter study, we performed HDL on 82 male patients using reciprocating power-assisted liposuction under tumescent local anesthesia with both lidocaine and prilocaine. No drains were used. Intraoperative and postoperative data were collected, and complication and satisfaction rates were evaluated after 6 months. All overall patients’ satisfaction was high. There were no major complications. Minor complications included seroma (n = 4), and 3 patients required touch-up surgery. There were no side-effects from the anesthesia, and there was no fluid overload. High-definition liposculpture using reciprocating power-assisted liposuction in local anesthesia is a safe procedure with a high satisfaction rate.


2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Magali Kouidhi ◽  
Phi Villageois ◽  
Carine M. Mounier ◽  
Corinne Ménigot ◽  
Yves Rival ◽  
...  

Animal study findings have revealed that individual fat depots are not functionally equivalent and have different embryonic origins depending on the anatomic location. Mouse bone regeneration studies have also shown that it is essential to match theHoxcode of transplanted cells and host tissues to achieve correct repair. However, subcutaneous fat depots from any donor site are often used in autologous fat grafting. Our study was thus carried out to determine the embryonic origins of human facial (chin) and limb (knee) fat depots and whether they had similar features and molecular matching patterns. Paired chin and knee fat depots were harvested from 11 subjects and gene expression profiles were determined by DNA microarray analyses. Adipose-derived stromal cells (ASCs) from both sites were isolated and analyzed for their capacity to proliferate, form clones, and differentiate. Chin and knee fat depots expressed a differentHOXcode and could have different embryonic origins. ASCs displayed a different phenotype, with chin-ASCs having the potential to differentiate into brown-like adipocytes, whereas knee-ASCs differentiated into white adipocytes. These results highlighted different features for these two fat sites and indicated that donor site selection might be an important factor to be considered when applying adipose tissue in cell-based therapies.


1989 ◽  
Vol 48 (1) ◽  
pp. 203-212 ◽  
Author(s):  
C. T. Whittemore ◽  
H. Yang

ABSTRACTThe physical and chemical composition of sows was determined at first mating (no. = 6), weaning the first litter (12) and 14 days after weaning the fourth litter (24). The sows were from 108 Large White/Landrace Fl hybrid gilts allocated in a factorial arrangement according to two levels of subcutaneous fatness at parturition (12 v. 22 mm P2), two levels of lactation feeding (3 v. 7 kg) and two sizes of sucking litter (six v. 10). Treatments significantly influenced the composition of dissected carcass fat and chemical lipid, but not composition of dissected lean and chemical protein. The final body protein mass of well fed sows at the termination of parity 4 was 41 kg, and the total content of gross energy (GE) in excess of 3000 MJ, with an average of 12·4 MJ GE per kg live weight; equivalent values for the less well fed sows were 33 kg and 9·4 MJ GE per kg live weight respectively. The weights of chemical lipid and protein could be predicted from the equations: lipid (kg) = -20·4 (s.e. 4·5) + 0·21 (s.e. 0·02) live weight + 1·5 (s.e. 0·2) P2; protein (kg) = -2·3 (s.e. 1·6) + 0·19 (s.e. 0·01) live weight - 0·22 (s.e. 0·07) P2. On average, sows lost 9 kg lipid and 3 kg protein in the course of the 28-day lactation; these being proportionately about 0·16 and 0·37 of the live-weight losses respectively. Maternal energy requirement for maintenance was estimated as 0·50 MJ digestible energy (DE) per kg M0·75, while the efficiency of use of DE for energy retention was 0·28.


2007 ◽  
Vol 157 (2) ◽  
pp. 167-174 ◽  
Author(s):  
Soo-Kyung Kim ◽  
Kyu-Yeon Hur ◽  
Hae-Jin Kim ◽  
Wan-Sub Shim ◽  
Chul-Woo Ahn ◽  
...  

Objective: The goal was to investigate the interrelationships between the hypoglycemic effects of rosiglitazone and the changes in the regional adiposity of type 2 diabetic patients. Design and methods: We added rosiglitazone (4 mg/day) to 173 diabetic patients (111 males and 62 females) already taking a stable dose of conventional antidiabetic medications except for thiazolidinediones. The abdominal fat distribution was assessed by ultrasonography at baseline and 12 weeks later. Using ultrasonographic images, the s.c. and visceral fat thickness (SFT and VFT respectively) were measured. Results: Rosiglitazone treatment for 3 months improved the glycemic control. However, the response to rosiglitazone was no more than 36.4%; the deterioration of the glycemic control was found in 16.8% of subjects. In addition, rosiglitazone treatment significantly increased the body fat mass, especially the s.c. fat. However that did not alter the visceral fat content. The percentage changes in fasting plasma glucose (FPG) and glycated hemoglobin (HbA1c) concentrations after treatment were inversely correlated with the increase in SFT (r=−0.327 and −0.353, P<0.001 respectively) and/or body weight (r=−0.316 and −0.327, P<0.001 respectively). Multiple regression analysis revealed that the improvement in the FPG after rosiglitazone treatment was correlated with the baseline FPG (P<0.001) and the change in the SFT (P=0.019), and the reduction in the HbA1c was related with the baseline FPG (P=0.003) and HbA1c (P<0.001) and the changes in the SFT (P=0.010) or VFT (P=0.013). Conclusions: The increase in the s.c. fat depot after rosiglitazone treatment may be an independent factor that determines the hypoglycemic efficacy.


2011 ◽  
Vol 40 (5) ◽  
pp. 1095-1103 ◽  
Author(s):  
Gustavo Chamon de Castro Menezes ◽  
Sebastião de Campos Valadares Filho ◽  
Felipe Antunes Magalhães ◽  
Rilene Ferreira Diniz Valadares ◽  
Laura Franco Prados ◽  
...  

It was evaluated intake, total apparent digestibility, performance and feeding behavior of bovine fed diets constituted of corn silage, crushed sugar cane given fresh or crushed and given 72 hours after storage, ensilaged sugar cane with or without 1% of calcium oxide and concentrate at the proportion of 1% of the body weight. It was used 35 bovines, distributed in a random block design, with 5 treatments and 6 repetitions. The animals were housed in collective stalls with troughs individualized by electronic gates. The animals fed diet with corn silage presented greater intake of all nutrients and greater total digestibility of dry matter, organic matter, neutral detergent fiber and total digestible nutrients, as well as greater weight gain and subcutaneous fat thickness. Animals fed diet with fresh sugar cane presented greater nutrient intake as well as better dry matter digestibility, ether extract and TDN content and a superior performance in relation to animals fed ensilaged sugar cane diets. Animals fed silage of sugar cane with calcium oxide presented greater digestibility of organic matter, NFC and content of TDN but they did not differ on performance in relation to the use of silage of sugar cane without calcium oxide. Intake and performance of animals did not change with or without storage of sugar cane. It was concluded that animals fed diets with corn silage present performances superior to the ones which are fed sugar cane based diets, and animals fed fresh sugar diet are superior to the animals fed diets with sugar cane silage.


1993 ◽  
Vol 265 (2) ◽  
pp. E323-E331 ◽  
Author(s):  
H. Kurachi ◽  
H. Adachi ◽  
S. Ohtsuka ◽  
K. Morishige ◽  
K. Amemiya ◽  
...  

Ovariectomy (Ovx) of mice significantly increases the epidermal growth factor (EGF) concentration in the submandibular gland. To elucidate the role of this elevated EGF in obesity of Ovx mice, we examined the effects of sialoadenectomy (Sx) and anti-EGF rabbit antiserum administration on the body weight (BW) gain and carcass fat deposition in Ovx animals. Studies were performed in four groups of mice consisting of control, Ovx, Ovx+Sx, and Ovx+anti-EGF groups. Ovx increased the BW gain compared with the control animals, whereas Sx and anti-EGF significantly reduced it. Although the relative weights (weight ratio to BW) of the liver and kidney were not significantly changed by Ovx, Sx, or anti-EGF treatment of Ovx mice, the relative weights of mesenteric, parametrial, and subcutaneous fat tissues were increased in Ovx mice, and this increase was significantly reduced by Sx or anti-EGF administration. Ovx induced adipocyte hypertrophy, and this effect was eliminated by Sx and anti-EGF. Moreover, acyl-CoA synthetase mRNA level was increased by Ovx, and this increase was reduced by Sx and anti-EGF in mesenteric fat tissue. These findings suggest that elevation of EGF may play a role in the induction of obesity in Ovx mice.


Animals ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 287 ◽  
Author(s):  
Israel L. Mullins ◽  
Carissa M. Truman ◽  
Magnus R. Campler ◽  
Jeffrey M. Bewley ◽  
Joao H. C. Costa

Body condition scoring (BCS) is the management practice of assessing body reserves of individual animals by visual or tactile estimation of subcutaneous fat and muscle. Both high and low BCS can negatively impact milk production, disease, and reproduction. Visual or tactile estimation of subcutaneous fat reserves in dairy cattle relies on their body shape or thickness of fat layers and muscle on key areas of the body. Although manual BCS has proven beneficial, consistent qualitative scoring can be difficult to implement. The desirable BCS range for dairy cows varies within lactation and should be monitored at multiple time points throughout lactation for the most impact, a practice that can be hard to implement. However, a commercial automatic BCS camera is currently available for dairy cattle (DeLaval Body Condition Scoring, BCS DeLaval International AB, Tumba, Sweden). The objective of this study was to validate the implementation of an automated BCS system in a commercial setting and compare agreement of the automated body condition scores with conventional manual scoring. The study was conducted on a commercial farm in Indiana, USA, in April 2017. Three trained staff members scored 343 cows manually using a 1 to 5 BCS scale, with 0.25 increments. Pearson’s correlations (0.85, scorer 1 vs. 2; 0.87, scorer 2 vs. 3; and 0.86, scorer 1 vs. 3) and Cohen’s Kappa coefficients (0.62, scorer 1 vs. 2; 0.66, scorer 2 vs. 3; and 0.66, scorer 1 vs. 3) were calculated to assess interobserver reliability, with the correlations being 0.85, 0.87, and 0.86. The automated camera BCS scores were compared with the averaged manual scores. The mean BCS were 3.39 ± 0.32 and 3.27 ± 0.27 (mean ± SD) for manual and automatic camera scores, respectively. We found that the automated body condition scoring technology was strongly correlated with the manual scores, with a correlation of 0.78. The automated BCS camera system accuracy was equivalent to manual scoring, with a mean error of −0.1 BCS and within the acceptable manual error threshold of 0.25 BCS between BCS (3.00 to 3.75) but was less accurate for cows with high (>3.75) or low (<3.00) BCS scores compared to manual scorers. A Bland–Altman plot was constructed which demonstrated a bias in the high and low automated BCS scoring. The initial findings show that the BCS camera system provides accurate BCS between 3.00 to 3.75 but tends to be inaccurate at determining the magnitude of low and high BCS scores. However, the results are promising, as an automated system may encourage more producers to adopt BCS into their practices to detect early signs of BCS change for individual cattle. Future algorithm and software development is likely to increase the accuracy in automated BCS scoring.


Sign in / Sign up

Export Citation Format

Share Document