Early Detection of Ototoxicity Using 1/6th-Octave Steps

2003 ◽  
Vol 14 (08) ◽  
pp. 444-450 ◽  
Author(s):  
Stephen A. Fausti ◽  
Wendy J. Helt ◽  
David S. Phillips ◽  
Jane S. Gordon ◽  
Gene W. Bratt ◽  
...  

The National Center for Rehabilitative Auditory Research has developed a protocol to provide early identification of ototoxicity for patients receiving ototoxic medications. The initial work involved patients with relatively good high-frequency hearing and resulted in the use of an individualized, sensitive frequency range separated by 1/16th-octave intervals. This protocol tested puretone frequencies at 1/6th-octave steps above 9 kHz, but only conventional audiometric frequencies were tested below 9 kHz. More recently, the testing protocol was expanded to include 1/6th-octave testing below 9 kHz. The primary question of interest was to determine whether adding 1/16th-octave test frequencies below 9 kHz would increase the ototoxicity detection rate for patients with poorer hearing. Results indicated 76 of the 210 (36.2%) ears that demonstrated initial ototoxic hearing change would have been missed or detected later if only conventional frequency testing was conducted. Therefore, for individuals with poorer hearing, expanding the use of the 1/16th-octave test protocol provides earlier identification of ototoxicity.

1971 ◽  
Vol 36 (4) ◽  
pp. 527-537 ◽  
Author(s):  
Norman P. Erber

Two types of special hearing aid have been developed recently to improve the reception of speech by profoundly deaf children. In a different way, each special system provides greater low-frequency acoustic stimulation to deaf ears than does a conventional hearing aid. One of the devices extends the low-frequency limit of amplification; the other shifts high-frequency energy to a lower frequency range. In general, previous evaluations of these special hearing aids have obtained inconsistent or inconclusive results. This paper reviews most of the published research on the use of special hearing aids by deaf children, summarizes several unpublished studies, and suggests a set of guidelines for future evaluations of special and conventional amplification systems.


2017 ◽  
Vol 76 (10) ◽  
pp. 929-940 ◽  
Author(s):  
Yu. S. Kovshov ◽  
S. S. Ponomarenko ◽  
S. A. Kishko ◽  
A. A. Likhachev ◽  
S. A. Vlasenko ◽  
...  

2021 ◽  
Vol 11 (4) ◽  
pp. 1932
Author(s):  
Weixuan Wang ◽  
Qinyan Xing ◽  
Qinghao Yang

Based on the newly proposed generalized Galerkin weak form (GGW) method, a two-step time integration method with controllable numerical dissipation is presented. In the first sub-step, the GGW method is used, and in the second sub-step, a new parameter is introduced by using the idea of a trapezoidal integral. According to the numerical analysis, it can be concluded that this method is unconditionally stable and its numerical damping is controllable with the change in introduced parameters. Compared with the GGW method, this two-step scheme avoids the fast numerical dissipation in a low-frequency range. To highlight the performance of the proposed method, some numerical problems are presented and illustrated which show that this method possesses superior accuracy, stability and efficiency compared with conventional trapezoidal rule, the Wilson method, and the Bathe method. High accuracy in a low-frequency range and controllable numerical dissipation in a high-frequency range are both the merits of the method.


2018 ◽  
Vol 7 (2.8) ◽  
pp. 529 ◽  
Author(s):  
Ch Ramakrishna ◽  
G A.E.Satish Kumar ◽  
P Chandra Sekhar Reddy

This paper presents a band notched WLAN self complementaryultra wide band antenna for wireless applications. The proposed antenna encounters a return loss (RL) less than -10dB for entire ultra wideband frequency range except band notched frequency. This paper proposes a hexagon shape patch, edge feeding, self complementary technique and defective ground structure. The antenna has an overall dimensionof 28.3mm × 40mm × 2mm, builton  substrate FR4 with a relative dielectric permittivity 4.4. And framework is simulated finite element method with help of high frequency structured simulator HFSSv17.2.the proposed antenna achieves a impedance bandwidth of 8.6GHz,  band rejected WLAN frequency range 5.6-6.5 GHz with  vswr is less than 2.


2019 ◽  
Vol 9 (15) ◽  
pp. 3157 ◽  
Author(s):  
O ◽  
Jin ◽  
Choi

In this paper, we propose a compact four-port coplanar antenna for cognitive radio applications. The proposed antenna consists of a coplanar waveguide (CPW)-fed ultra-wideband (UWB) antenna and three inner rectangular loop antennas. The dimensions of the proposed antenna are 42 mm × 50 mm × 0.8 mm. The UWB antenna is used for spectrum sensing and fully covers the UWB spectrum of 3.1–10.6 GHz. The three loop antennas cover the UWB frequency band partially for communication purposes. The first loop antenna for the low frequency range operates from 2.96 GHz to 5.38 GHz. The second loop antenna is in charge of the mid band from 5.31 GHz to 8.62 GHz. The third antenna operates from 8.48 GHz to 11.02 GHz, which is the high-frequency range. A high isolation level (greater than 17.3 dB) is realized among the UWB antenna and three loop antennas without applying any additional decoupling structures. The realized gains of the UWB antenna and three loop antennas are greater than 2.7 dBi and 1.38 dBi, respectively.


2007 ◽  
Vol 60 (1) ◽  
pp. 6 ◽  
Author(s):  
Simon Schrödle ◽  
Gary Annat ◽  
Douglas R. MacFarlane ◽  
Maria Forsyth ◽  
Richard Buchner ◽  
...  

A study of the room-temperature ionic liquid N-methyl-N-ethylpyrrolidinium dicyanamide by dielectric relaxation spectroscopy over the frequency range 0.2 GHz ≤ ν ≤ 89 GHz has revealed that, in addition to the already known lower frequency processes, there is a broad featureless dielectric loss at higher frequencies. The latter is probably due to the translational (oscillatory) motions of the dipolar ions of the IL relative to each other, with additional contributions from their fast rotation.


2015 ◽  
Vol 655 ◽  
pp. 182-185
Author(s):  
Ke Lan Yan ◽  
Run Hua Fan ◽  
Min Chen ◽  
Kai Sun ◽  
Xu Ai Wang ◽  
...  

The phase structure, and electrical and magnetic properties of La0.7Sr0.3MnO3(LSMO)-xAg (xis the mole ratio,x=0, 0.3, 0.5) composite were investigated. It is found that the sample withx=0 is single phase; the samples withx=0.3 and 0.5 present three phase composite structure of the manganese oxide and Ag. With the increasing of Ag content, the grain size of the samples increases and the grain boundaries transition from fully faceted to partially faceted. The permittivity of spectrum (10 MHz - 1 GHz) and the theoretical simulation reveal that the plasma frequencyfpincrease with Ag content, due to the increasing of free electron concentration, which is further supported by the enhancement of conductivity. While for the permeability (μr'), theμr'decrease with the increasing of Ag content at low frequency range (f< 20 MHz), while at the relative high frequency range (f> 300 MHz), theμr'increased with Ag content. Therefore, the introduction of elemental Ag resulted in a higherμr'at the relative high frequency range.


2005 ◽  
Vol 114 (3) ◽  
pp. 242-246
Author(s):  
Joni K. Doherty ◽  
Dennis R. Maceri

Proteus syndrome (PS) is a rare hamartomatous disorder characterized by mosaic overgrowth of multiple tissues that manifests early in life and is progressive. The presence of unilateral external auditory canal exostoses in a patient who is not a swimmer or surfer is suggestive of PS. However, hearing loss is not a typical feature. Here, we describe exostoses and ossicular discontinuity with conductive hearing loss in a patient with PS. The treatment consisted of canalplasty and ossicular chain reconstruction. A postoperative reduction was demonstrated in the patient's air-bone gap, from 21 dB to 13 dB for the pure tone average (four frequencies) and from 41 dB to 15 dB in the high-frequency range (6,000 to 8,000 Hz). Causes of ossicular discontinuity are discussed. Routine annual audiometric and otolaryngological evaluation should be considered in all patients with temporal bone inyolvement of PS.


2007 ◽  
Vol 280-283 ◽  
pp. 919-924
Author(s):  
M.S. Jogad ◽  
V.K. Shrikhande ◽  
A.H. Dyama ◽  
L.A. Udachan ◽  
Govind P. Kothiyal

AC and DC conductivities have been measured by using the real (e¢) and imaginary (e¢¢) parts of the dielectric constant data of glass and glass-ceramics (GC) at different temperatures in the rage 297-642K and in the frequency range 100 Hz to 10 MHz. Using Anderson –Stuart model, we have calculated the activation energy, which is observed to be lower than that of the DC conductivity. The analysis for glass/glass-ceramics indicates that the conductivity variation with frequency exhibits an initial linear region followed by nonlinear region with a maximum in the high-frequency region. The observed frequency dependence of ionic conductivity has been analyzed within the extended Anderson–Stuart model considering both the electrostatic and elastic strain terms. In glass/glassceramic the calculations based on the Anderson-Stuart model agree with the experimental observations in the low frequency region but at higher frequencies there is departure from measured data.


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