scholarly journals The role of animal nutrition in improving the nutritive value of animal-derived foods in relation to chronic disease

2005 ◽  
Vol 64 (3) ◽  
pp. 395-402 ◽  
Author(s):  
D. I. Givens
Keyword(s):  
Fatty Acid ◽  
Financial Incentives ◽  
Milk Fat ◽  
Nutritive Value ◽  
Animal Nutrition ◽  
Beneficial Effects ◽  
The Metabolic Syndrome ◽  
The Uk

Foods derived from animals are an important source of nutrients in the diet; for example, milk and meat together provide about 60 and 55% of the dietary intake of Ca and protein respectively in the UK. However, certain aspects of some animal-derived foods, particularly their fat and saturated fatty acid (SFA) contents, have led to concerns that these foods substantially contribute to the risk of CVD, the metabolic syndrome and other chronic diseases. In most parts of Europe dairy products are the greatest single dietary source of SFA. The fatty acid composition of various animal-derived foods is, however, not constant and can, in many cases, be enhanced by animal nutrition. In particular, milk fat with reduced concentrations of the C12–16SFA and an increased concentration of 18:1 MUFA is achievable, although enrichment with very-long-chainn-3 PUFA is much less efficient. However, there is now evidence that some animal-derived foods (notably milk products) contain compounds that may actively promote long-term health, and research is urgently required to fully characterise the benefits associated with the consumption of these compounds and to understand how the levels in natural foods can be enhanced. It is also vital that the beneficial effects are not inadvertently destroyed in the process of reducing the concentrations of SFA. In the future the role of animal nutrition in creating foods closer to the optimum composition for long-term human health is likely to become increasingly important, but production of such foods on a scale that will substantially affect national diets will require political and financial incentives and great changes in the animal production industry.

scholarly journals Duodenal Dysbiosis and Relation to the Efficacy of Proton Pump Inhibitors in Functional Dyspepsia

2021 ◽  
Vol 22 (24) ◽  
pp. 13609
Author(s):  
Lucas Wauters ◽  
Raúl Y. Tito ◽  
Matthias Ceulemans ◽  
Maarten Lambaerts ◽  
Alison Accarie ◽  
...  
Keyword(s):  
Functional Dyspepsia ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Potential Role ◽  
Short Term ◽  
Beneficial Effects ◽  
Rrna Sequencing ◽  
Before And After

Proton pump inhibitors (PPI) may improve symptoms in functional dyspepsia (FD) through duodenal eosinophil-reducing effects. However, the contribution of the microbiome to FD symptoms and its interaction with PPI remains elusive. Aseptic duodenal brushings and biopsies were performed before and after PPI intake (4 weeks Pantoprazole 40 mg daily, FD-starters and controls) or withdrawal (2 months, FD-stoppers) for 16S-rRNA sequencing. Between- and within-group changes in genera or diversity and associations with symptoms or duodenal factors were analyzed. In total, 30 controls, 28 FD-starters and 19 FD-stoppers were followed. Mucus-associated Porphyromonas was lower in FD-starters vs. controls and correlated with symptoms in FD and duodenal eosinophils in both groups, while Streptococcus correlated with eosinophils in controls. Although clinical and eosinophil-reducing effects of PPI therapy were unrelated to microbiota changes in FD-starters, increased Streptococcus was associated with duodenal PPI effects in controls and remained higher despite withdrawal of long-term PPI therapy in FD-stoppers. Thus, duodenal microbiome analysis demonstrated differential mucus-associated genera, with a potential role of Porphyromonas in FD pathophysiology. While beneficial effects of short-term PPI therapy were not associated with microbial changes in FD-starters, increased Streptococcus and its association with PPIeffects in controls suggest a role for duodenal dysbiosis after long-term PPI therapy.

The context of healthcare

2020 ◽  
pp. 1-34
Keyword(s):  
Public Health ◽  
Primary Care ◽  
Northern Ireland ◽  
Healthcare Services ◽  
Health Profile ◽  
Long Term Conditions ◽  
Key Concepts ◽  
The Uk

This chapter begins by covering the UK health profile, then defines the key concepts in primary care and public health, and outlines the generic long-term conditions model. It provides a brief overview of the National Health Service, including differences in England, Northern Ireland, Scotland, and Wales. It covers current NHS entitlements for people from overseas, commissioning of services, and public health in a broader context. It also describes health needs assessment, and provides an overview of the services in primary care, the role of general practice, and other primary healthcare services. Further services, including those to prevent unplanned hospital admission, aid hospital discharge, those that support children and families, housing, social support, and care homes are all covered.

scholarly journals Alterations in the Fatty Acid Composition in Infant Formulas and ω3-PUFA Enriched UHT Milk during Storage

Foods ◽  
2019 ◽  
Vol 8 (5) ◽  
pp. 163 ◽  
Author(s):  
Luis Miguel Rodríguez-Alcalá ◽  
María V. Calvo ◽  
Javier Fontecha ◽  
Leocadio Alonso
Keyword(s):  
Fatty Acid ◽  
Milk Fat ◽  
Fatty Acid Content ◽  
Daily Intake ◽  
Fetal Life ◽  
Milk Products ◽  
Uht Milk ◽  
Beneficial Effects ◽  
Infant Formulae ◽  
The Central Nervous System

ω3-polyunsaturated fatty acids (PUFA) are known to have several beneficial effects, such as preventing the occurrence of cardiovascular events in adults and improving the development of the central nervous system during fetal life and childhood. Dairy products enriched in PUFA are now available on the market and can help consumers to meet the ω3-PUFA daily intake recommendations. Although PUFA are prone to oxidation, little information exists regarding the alterations they undergo when products containing PUFA are stored. In this study, five infant formulae (IF) and five ω3-PUFA enriched Ultra High Temperature (UHT)-milk products were examined during storage at room temperature in terms of fatty acid (FA) composition and trans fatty acid (tFA) content until the end of shelf life by chromatography techniques. The IF included two follow-on formulae, two first-age formulae and a special medical purpose formula with different fat contents (from 2.6% to 27.7%). In the ω3-PUFA enriched UHT-milk products the milk fat was replaced by eicosapentanoic fatty acid (EPA) and docosahexaenoic acid (DHA) rich oils. The fatty acid content of all samples remained stable whereas some variations were observed for the tFA isomer content (p < 0.05) in the UHT-milk samples.

scholarly journals Role of Oleic Acid in the Gut-Liver Axis: From Diet to the Regulation of Its Synthesis via Stearoyl-CoA Desaturase 1 (SCD1)

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2283 ◽  
Author(s):  
Elena Piccinin ◽  
Marica Cariello ◽  
Stefania De Santis ◽  
Simon Ducheix ◽  
Carlo Sabbà ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Fatty Acid ◽  
Olive Oil ◽  
Intestinal Inflammation ◽  
Principal Component ◽  
Monounsaturated Fatty Acids ◽  
Beneficial Effects ◽  
Stearoyl Coa Desaturase ◽  
The Impact

The consumption of an olive oil rich diet has been associated with the diminished incidence of cardiovascular disease and cancer. Several studies have attributed these beneficial effects to oleic acid (C18 n-9), the predominant fatty acid principal component of olive oil. Oleic acid is not an essential fatty acid since it can be endogenously synthesized in humans. Stearoyl-CoA desaturase 1 (SCD1) is the enzyme responsible for oleic acid production and, more generally, for the synthesis of monounsaturated fatty acids (MUFA). The saturated to monounsaturated fatty acid ratio affects the regulation of cell growth and differentiation, and alteration in this ratio has been implicated in a variety of diseases, such as liver dysfunction and intestinal inflammation. In this review, we discuss our current understanding of the impact of gene-nutrient interactions in liver and gut diseases, by taking advantage of the role of SCD1 and its product oleic acid in the modulation of different hepatic and intestinal metabolic pathways.

The effect of feeding high levels of fish oil and additional vitamin E on intake, milk yield, composition and fatty acid content in high yielding dairy cows

1998 ◽  
Vol 1998 ◽  
pp. 221-221 ◽  
Author(s):  
R J Mansbridge ◽  
J S Blake ◽  
C Collins
Keyword(s):  
Fatty Acid ◽  
Vitamin E ◽  
Fish Oil ◽  
Acid Content ◽  
Milk Fat ◽  
Fatty Acid Content ◽  
Epa And Dha ◽  
Oily Fish ◽  
The Uk ◽  
Effect Of Feeding

The COMA report on The Nutritional Aspects of Cardiovascular Disease (1994) recommended that the intake of long chain n-3 polyunsaturated fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), by the UK population should double. EPA and DHA in the human diet are derived principally from oily fish. The aim of this experiment was to determine the effect of increasing levels of fish oil in the diet at two levels of vitamin E supplementation, on intake, milk production, the extent of uptake of EPA and DHA into milk fat at levels exceeding those investigated to date, and the effect of a dietary supplement of vitamin E on fatty acid content.

Geospatial data in the UK

2019 ◽  
Vol 33 (1) ◽  
pp. 27-41 ◽  
Author(s):  
Suzanne Jozefowicz ◽  
Merlin Stone ◽  
Eleni Aravopoulou
Keyword(s):  
Western Country ◽  
Geospatial Data ◽  
Content Type ◽  
Research Findings ◽  
Potential Benefits ◽  
Uk Government ◽  
The Government ◽  
The Uk

Purpose The purpose of this paper is to explain the rise of geospatial data, its importance for business and some of the problems associated with its development and use. Design/methodology/approach The paper reviews a certain amount of previously published literature but is based mainly on analysis of the very large number of responses to a consultation paper on geospatial data published by the UK Government. Findings The findings are that while there is strong appreciation of the potential benefits of using geospatial data, there are many barriers to the development, sharing and use of geospatial data, ranging from problems of incompatibility in data definitions and systems to regulatory issues. The implication for governments and for providers and users of geospatial data relates to the need to take a long-term approach to planning in resolving the issues identified. Research limitations/implications The research findings are limited to the UK, but similar findings would be likely in any other large Western country. Practical implications This paper confirms the need for a strong and coherent approach to the planning of geospatial data and systems for the establishment of a clear basis for the different parties to work together and the need to clearly separate the roles of the government in establishing frameworks and standards and the role of the private sector in developing applications and solutions. Social implications Society is increasingly dependent on the use of geospatial data, in improving living standards and dealing with social problems. The recommendations identified in this paper, if followed, will facilitate these improvements. Originality/value The value of this paper is the tight synthesis that it provides of a wide ranging and complex range of responses to the UK Government consultation and placing these responses in the wider context of the development of geospatial data.

scholarly journals Translation, Copyright & Authority

Pólemos ◽  
2018 ◽  
Vol 12 (2) ◽  
pp. 361-391 ◽  
Author(s):  
Alan Cunningham
Keyword(s):  
Institutional Change ◽  
Critical Point ◽  
Copyright Law ◽  
The Uk ◽  
The Right

Abstract The UK copyright law regime presents the right to adapt as the sole, authoritative instrument in matters of legitimising translation; a legal “Big Other” conferring an otherwise unreal objective commodity status on what are instead always only ever individual and subjective acts of translation. Drawing primarily on the work of Theo Hermans, and the experiences of poet Jack Underwood in unsuccessfully attempting to formally translate poems by Mascha Kaléko, this article argues for (a) the development and (at the very least) implicit recognition of deviationist and subversive translative replies within – or at the very least alongside – the traditional UK legal schema and (b) a softening of the UK right to adapt by application of the integrity moral right to translations. In addition, a deeper quasi-Ungerian notion of institutional change that accommodates both principles (e. g. legitimate translations can, of course, be argued to exist, to which copyright accords) and counterprinciples (there are also, however, in the long term only multiple acts of translation, some preferred and commoditized, some existing outside that sphere, less functional and more creative/expressive but no less important and not to be prevented for those reasons) can also be advanced. Finally, a much broader critical point regarding the nature and role (or non-role) of law in the context of creative practices more generally can also be presented.

Work and Welfare Benefits: Social Security, Employment and Unemployment in the 1990s

1991 ◽  
Vol 20 (4) ◽  
pp. 485-508 ◽  
Author(s):  
Eithne McLaughlin
Keyword(s):  
Social Security ◽  
Labour Market ◽  
Security Policy ◽  
Social Security Systems ◽  
Security Systems ◽  
Welfare Benefits ◽  
The Uk ◽  
Social Security Policy

ABSTRACTThis paper considers social security policy and structures in relation to the labour market of the late 1980s and 1990s. The paper begins by describing the labour market of the late 1980s and summarising projective descriptions of labour demand in the 1990s. The second section of the paper reports on recent research examining the labour supply behaviour of long term unemployed people, drawing out the role of social security policy and structures therein. The third section of the paper concludes that the role of social security policy is at present essentially reactive rather than proactive; that it does little to address the likely need for labour of certain kinds in the 1990s; and that efforts to address the problem of long term unemployment through social security policy have been largely misdirected. The final section of the paper briefly considers some of the ways in which social security systems can be more proactive and suggests a number of both short term and longer term policy changes which research indicates would be of benefit in the UK.

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