Total Polyphenol Intake, Polyphenol Subtypes, and Prevalence of Hypertension in the CUME Cohort

2021 ◽  
pp. 1-12
Author(s):  
Hillary Nascimento Coletro ◽  
Josefina Bressan ◽  
Amanda Popolino Diniz ◽  
Helen Hermana Miranda Hermsdorff ◽  
Adriano Marçal Pimenta ◽  
...  
Keyword(s):  
Total Polyphenol ◽  
Polyphenol Intake

scholarly journals Validity of a food frequency questionnaire for the estimation of total polyphenol intake estimates and its major food sources in the Japanese population: the JPHC FFQ Validation Study

2021 ◽  
Vol 10 ◽  
Author(s):  
Nagisa Mori ◽  
Norie Sawada ◽  
Junko Ishihara ◽  
Ayaka Kotemori ◽  
Ribeka Takachi ◽  
...  
Keyword(s):  
Validation Study ◽  
Food Frequency Questionnaire ◽  
Japanese Population ◽  
Alcoholic Beverages ◽  
Food Sources ◽  
Total Polyphenol ◽  
Food Frequency ◽  
Dietary Polyphenols ◽  
Dietary Record ◽  
Polyphenol Intake

Abstract We examine the validity and reproducibility of a food frequency questionnaire (FFQ) in a subsample of participants in the Japan Public Health Center-based Prospective Cohort Study using a database of polyphenol-containing foods commonly consumed in the Japanese population. Participants of the validation study were recruited from two different cohorts. In Cohort I, 215 participants completed a 28-d dietary record (DR) and the FFQ, and in Cohort II, 350 participants completed DRs and the FFQ. The total polyphenol intake estimated from the 28-d DR and FFQ were log-transformed and adjusted for energy intake by the residual method. Spearman correlation coefficients (CCs) between estimates from the FFQ and 28-d DR as well as two FFQs administered at a 1-year interval were computed. Median intakes of dietary polyphenols calculated from the DRs were 1172 mg/d for men and 1024 mg/d for women in Cohort I, and 1061 mg/d for men and 942 mg/d for women in Cohort II. The de-attenuated CCs for polyphenol intake between the DR and FFQ were 0⋅47 for men and 0⋅37 for women in Cohort I and 0⋅44 for men and 0⋅50 for women in Cohort II. Non-alcoholic beverages were the main contributor to total polyphenol intake in both men and women, accounting for 50 % of total polyphenol intake regardless of cohort and gender, followed by alcoholic beverages and seasoning and spices in men, and seasoning and spices, fruits and other vegetables in women. The present study showed that this FFQ had moderate validity and reproducibility and is suitable for use in future epidemiological studies.

scholarly journals Relation Between Total Polyphenol Intake and Markers of Intestinal Health in Obese Humans

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1592-1592
Author(s):  
Victoria Teixeira Reis ◽  
Christy Tangney ◽  
Ali Keshavarzian ◽  
Alexander Racine ◽  
Weiwen Chai ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Health Outcomes ◽  
Intestinal Permeability ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Intestinal Health ◽  
Total Polyphenol ◽  
Gastrointestinal Health ◽  
Polyphenol Intake ◽  
Systemic Health

Abstract Objectives Polyphenol intake has been associated with improved health outcomes, but the relation between polyphenol intake, gastrointestinal health, and systemic health outcomes is not fully known. Many polyphenols become bioavailable once transformed into metabolites by the gut microbial community. Thus, it is reasonable to assume that the intimate interaction between polyphenols and microbiota may influence both gastrointestinal and systemic health. The objective of the current study was to assess the relation of daily polyphenol intake with intestinal permeability, microbiota profile, and fecal short-chain fatty acids in a sample of obese humans. Methods The analyses were conducted among 92 adult obese participants (body mass index ≥ 30 kg/m2). Polyphenol intake was calculated from a food frequency questionnaire (VioscreenTM) using Polyphenol-Explorer and published literature. Intestinal permeability was measured through collection of 24-hour urine after consumption of a sugar mixture and presented as sucralose and sucralose: lactulose excretion as a % of the oral dose. Microbiota profile and short-chain fatty acids (SCFA) were assessed using 16S sequencing and gas chromatography, respectively. Associations of polyphenol intake between intestinal health markers were examined by correlational analyses; all analyses were conducted using SPSS (version 26). Results Mean age of participants was 44.1 ± 11.3 years; 70.7% were females and 63.0% self-identified as Black/African American. Daily polyphenol intake was 2,733 ± 2,129 mg/day. Primary food group contributors to polyphenol intake were drinks (coffee/tea; 33.2%), fruit (23.9%) and vegetarian protein sources (nuts/seeds/legumes; 15.6%). Total polyphenol intake was positively correlated with fecal butyrate (µg/g) (rho = 0.255; p = 0.029) and butyrate: SCFA ratio (rho = 0.274, p = 0.018). However, polyphenol intake was not correlated to microbiota taxa or markers of intestinal permeability (P > 0.05). Conclusions Dietary intake of polyphenols are associated with fecal SCFA concentrations, but further investigation through intervention studies is needed to elucidate the potential relation between polyphenols and markers of gastrointestinal health. Funding Sources Supported by the Agriculture and Food Research Initiative from the USDA National Institute of Food and Agriculture.

scholarly journals Poor Dietary Polyphenol Intake in Childhood Cancer Patients

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2835 ◽  
Author(s):  
Ashly Liu ◽  
Jennifer Cohen ◽  
Orazio Vittorio
Keyword(s):  
Childhood Cancer ◽  
Cancer Patients ◽  
Food Sources ◽  
Total Polyphenol ◽  
Nutritional Interventions ◽  
Dietary Recall ◽  
Consumption Data ◽  
Food Consumption Data ◽  
The Mean ◽  
Polyphenol Intake

Emerging research demonstrates polyphenol-rich diets like the Mediterranean diet may play a role in improving the outcomes of adult cancer therapy. To date, there are no trials assessing the intake or efficacy of polyphenol-rich diets in childhood cancer patients. In this study we collected dietary data on 59 childhood cancer patients on treatment using a three-pass 24-h dietary recall (24-HDR), which is based on a validated and structured three-part methodology. Polyphenol consumption was calculated by matching the food consumption data with polyphenol content extracted from the most updated Phenol-Explorer database. The mean total polyphenol intake was 173.31 ± 141.02 mg/day. The major food sources of polyphenols were fruits, beverages, and cereals. There were no significant associations with time since diagnosis, body mass index (BMI) z-score, types of cancer, treatment intensity, food-related symptoms, relapse, and total daily polyphenol intake. Further investigation with larger studies will facilitate the steps in assessing the value of polyphenol-rich dietary patterns in future nutritional interventions for childhood cancer patients.

scholarly journals Adherence to UK dietary guidelines is associated with higher dietary intake of total and specific polyphenols compared with a traditional UK diet: further analysis of data from the Cardiovascular risk REduction Study: Supported by an Integrated Dietary Approach (CRESSIDA) randomised controlled trial

2018 ◽  
Vol 121 (4) ◽  
pp. 402-415 ◽  
Author(s):  
Monica L. Castro-Acosta ◽  
Thomas A. B. Sanders ◽  
Dianne P. Reidlinger ◽  
Julia Darzi ◽  
Wendy L. Hall
Keyword(s):  
Cardiovascular Risk ◽  
Dietary Intake ◽  
Urinary Excretion ◽  
Controlled Trial ◽  
Dietary Guidelines ◽  
Control Group ◽  
Cardiovascular Risk Reduction ◽  
Total Polyphenol ◽  
Polyphenol Intake ◽  
Randomised Controlled

AbstractAdherence to dietary guidelines (DG) may result in higher intake of polyphenols via increased consumption of fruits, vegetables and whole grains. We compared polyphenol dietary intake and urinary excretion between two intervention groups in the Cardiovascular risk REduction Study: Supported by an Integrated Dietary Approach study: a 12-week parallel-arm, randomised controlled trial (n161; sixty-four males, ninety-seven females; aged 40–70 years). One group adhered to UK DG, whereas the other group consumed a representative UK diet (control). We estimated polyphenol dietary intake, using a 4-d food diary (4-DFD) and FFQ, and analysed 24-h polyphenol urinary excretion by liquid chromatography-tandem MS on a subset of participants (n46 control;n45 DG). A polyphenol food composition database for 4-DFD analysis was generated using Phenol-Explorer and USDA databases. Total polyphenol intake by 4-DFD at endpoint (geometric means with 95 % CI, adjusted for baseline and sex) was significantly higher in the DG group (1279 mg/d per 10 MJ; 1158, 1412) compared with the control group (1084 mg/d per 10 MJ; 980, 1197). The greater total polyphenol intake in the DG group was attributed to higher intake of anthocyanins, proanthocyanidins and hydroxycinnamic acids, with the primary food sources being fruits, cereal products, nuts and seeds. FFQ estimates of flavonoid intake also detected greater intake in DG compared with the control group. 24-h urinary excretion showed consistency with 4-DFD in their ability to discriminate between dietary intervention groups for six out of ten selected, individual polyphenols. In conclusion, following UK DG increased total polyphenol intake by approximately 20 %, but not all polyphenol subclasses corresponded with this finding.

Total polyphenol intake, polyphenol subtypes and incidence of cardiovascular disease: The SUN cohort study

2019 ◽  
Vol 29 (1) ◽  
pp. 69-78 ◽  
Author(s):  
R.D. Mendonça ◽  
N.C. Carvalho ◽  
J.M. Martin-Moreno ◽  
A.M. Pimenta ◽  
A.C.S. Lopes ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Cohort Study ◽  
The Sun ◽  
Total Polyphenol ◽  
Polyphenol Intake

scholarly journals Dietary intake of total polyphenols and the risk of all-cause and specific-cause mortality in Japanese adults: the Takayama study

2019 ◽  
Vol 59 (3) ◽  
pp. 1263-1271 ◽  
Author(s):  
Chie Taguchi ◽  
Yoshimi Kishimoto ◽  
Yoichi Fukushima ◽  
Kazuo Kondo ◽  
Michiyo Yamakawa ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Causes Of Death ◽  
Epidemiological Studies ◽  
Population Based ◽  
Inverse Association ◽  
Total Polyphenol ◽  
All Cause Mortality ◽  
Polyphenol Intake ◽  
Risk Of Cancer ◽  
Cvd Mortality

Abstract Purpose Several epidemiological studies have demonstrated the health benefits of polyphenols, but the associations between polyphenol intake and mortality including total and major causes of death remain unclear. We investigated the associations between subjects’ total polyphenol intake and their mortality from all causes, cardiovascular disease (CVD), cancer, and other causes of death in a population-based cohort study in Japan. Methods A total of 29,079 residents of Takayama City, Japan were analyzed. Their dietary intake was assessed using a validated semi-quantitative food-frequency questionnaire (FFQ) in 1992. Mortality was ascertained over the subsequent 16 years. The dietary polyphenol intake was calculated by matching the subjects’ food consumption data with our original polyphenol content database. Results A total of 5339 deaths occurred during the follow-up. After multivariable adjustment, the highest quartile of total polyphenol intake compared with the lowest quartile was significantly associated with a lower risk of all-cause mortality (HR: 0.93, 95% CI: 0.82–0.99, p trend = 0.003). The subjects in the highest quartile showed significantly lower CVD mortality compared to those in the lowest quartile, and among the types of CVD mortality, a strong inverse association was observed for stroke mortality. Inverse associations were also observed for mortality from other causes, specifically digestive disease. The total polyphenol intake was not significantly associated with the risk of cancer mortality. Conclusions The results of this prospective study indicate that dietary total polyphenol intake in Japanese is inversely associated with all-cause mortality and mortality from cardiovascular and digestive diseases.

scholarly journals Systematic Review on Polyphenol Intake and Health Outcomes: Is there Sufficient Evidence to Define a Health-Promoting Polyphenol-Rich Dietary Pattern?

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1355 ◽  
Author(s):  
Bo’ ◽  
Bernardi ◽  
Marino ◽  
Porrini ◽  
Tucci ◽  
...  
Keyword(s):  
Systematic Review ◽  
Protective Effect ◽  
Dietary Pattern ◽  
Critical Mass ◽  
Sufficient Evidence ◽  
Total Polyphenol ◽  
Large Variability ◽  
Health Promoting ◽  
Large Heterogeneity ◽  
Polyphenol Intake

Growing evidence support association between polyphenol intake and reduced risk for chronic diseases, even if there is a broad debate about the effective amount of polyphenols able to exert such protective effect. The present systematic review provides an overview of the last 10-year literature on the evaluation of polyphenol intake and its association with specific disease markers and/or endpoints. An estimation of the mean total polyphenol intake has been performed despite the large heterogeneity of data reviewed. In addition, the contribution of dietary sources was considered, suggesting tea, coffee, red wine, fruit and vegetables as the main products providing polyphenols. Total flavonoids and specific subclasses, but not total polyphenols, have been apparently associated with a low risk of diabetes, cardiovascular events and all-cause mortality. However, large variability in terms of methods for the evaluation and quantification of polyphenol intake, markers and endpoints considered, makes it still difficult to establish an evidence-based reference intake for the whole class and subclass of compounds. Nevertheless, the critical mass of data available seem to strongly suggest the protective effect of a polyphenol-rich dietary pattern even if further well targeted and methodologically sound research should be encouraged in order to define specific recommendations.

scholarly journals The Relationship between Dietary Polyphenol Intakes and Urinary Polyphenol Concentrations in Adults Prescribed a High Vegetable and Fruit Diet

Nutrients ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3431
Author(s):  
Erin D. Clarke ◽  
Megan E. Rollo ◽  
Clare E. Collins ◽  
Lisa Wood ◽  
Robin Callister ◽  
...  
Keyword(s):  
Hippuric Acid ◽  
Mixed Model ◽  
Linear Mixed Model ◽  
Total Polyphenol ◽  
Spot Urine ◽  
Dietary Polyphenols ◽  
Polyphenol Intake ◽  
Study Participants ◽  
The Relationship ◽  
Time Point

Urinary polyphenol metabolites are potential biomarkers of dietary polyphenol intake. The current study aims to evaluate associations between total diet, vegetable and fruit polyphenol intakes with urinary polyphenol metabolite concentrations in a sample of adults prescribed a diet rich in vegetables and fruit. Thirty-four participants completed a 10-week pre-post study. Participants were asked to consume Australian recommended daily vegetable and fruit serves and attend measurement sessions at baseline and at weeks 2 and 10. Two 24-h diet recalls were collected at each time-point and polyphenol intakes were calculated using the Phenol-Explorer database. Spot urine samples, collected at each time-point, were analyzed for 15 polyphenol metabolites using liquid chromatography-mass spectroscopy. Spearman’s correlation analyzes assessed the strength of relationships between urinary and dietary polyphenols. Linear mixed models were used to investigate relationships between polyphenol excretion and intake. Total urinary polyphenols were significantly correlated with total polyphenol intakes at week 10 (rs = 0.47) and fruit polyphenols at week 2 (rs = 0.38). Hippuric acid was significantly correlated with vegetable polyphenols at baseline (rs = 0.39). Relationships were identified between individual polyphenol metabolites and vegetable and fruit polyphenols. Linear mixed model analyzes identified that for every 1 mg increase in polyphenol intakes, urinary polyphenol excretion increased by 16.3 nmol/g creatinine. Although the majority of relationships were not sufficiently strong or consistent at different time-points, promising relationships were observed between total urinary polyphenols and total polyphenol intakes, and hippuric acid and vegetable polyphenols.

scholarly journals Comparison of polyphenol intakes according to distinct dietary patterns and food sources in the Adventist Health Study-2 cohort

2016 ◽  
Vol 115 (12) ◽  
pp. 2162-2169 ◽  
Author(s):  
Nasira Burkholder-Cooley ◽  
Sujatha Rajaram ◽  
Ella Haddad ◽  
Gary E. Fraser ◽  
Karen Jaceldo-Siegl
Keyword(s):  
Dietary Patterns ◽  
Relevant Literature ◽  
Food Sources ◽  
Health Study ◽  
Total Phenolic ◽  
Dietary Practices ◽  
Total Polyphenol ◽  
Dietary Polyphenols ◽  
Polyphenol Intake ◽  
Adventist Health Study

AbstractEvidence suggests a relationship between polyphenol intake and health benefits. Polyphenol intake among a large US cohort with diverse dietary practices ranging from meatless to omnivorous diets has not been previously evaluated. The primary aim of this study was to compare polyphenol intakes of several vegetarian and non-vegetarian dietary patterns and to assess phenolic intake by food source. To characterise dietary intake, a FFQ was administered to 77 441 participants of the Adventist Health Study-2. Dietary patterns were defined based on the absence of animal food consumption as vegan, lacto-ovo-vegetarian, pesco-vegetarian, semi-vegetarian and non-vegetarian. Polyphenol intakes were calculated based on chromatography-derived polyphenol content data of foods from Phenol-Explorer, US Department of Agriculture databases and relevant literature. Results revealed a mean unadjusted total polyphenol intake of 801 (sd 356) mg/d, and the main foods contributing to polyphenol intakes were coffee, fruits and fruit juices. Total polyphenol intake differed significantly between dietary patterns, with phenolic acids from coffee contributing the greatest variation. The dominant classes and sources of dietary polyphenols differed between vegetarian and non-vegetarian diets. Flavonoid intake was the highest among pesco-vegetarians, and phenolic acid intake was the highest among non-vegetarians. In addition, coffee consumers appeared to have a different dietary profile than non-coffee consumers, including greatly reduced contribution of fruits, vegetables and legumes to total phenolic intake. Coffee drinkers were more likely to be non-vegetarians, which explained several of these observations. Further evaluating these differences may be important in identifying relationships between plant-based diets and health outcomes.

Polyphenol intake and cognitive decline in the Seguimiento Universidad de Navarra (SUN) Project

2020 ◽  
pp. 1-10
Author(s):  
Leticia Goni ◽  
Marta Fernández-Matarrubia ◽  
Andrea Romanos-Nanclares ◽  
Cristina Razquin ◽  
Miguel Ruiz-Canela ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Cognitive Decline ◽  
Dietary Habits ◽  
Food Composition ◽  
Cognitive Status ◽  
Linear Regression Models ◽  
Cognitive Changes ◽  
Total Polyphenol ◽  
Polyphenol Intake ◽  
Sun Project

Abstract The global growing rates of cognitive decline and dementia, together with the absence of curative therapies for these conditions, support the interest in researching potential primary prevention interventions, with particular focus on dietary habits. The aim was to assess the association between polyphenol intake and 6-year change in cognitive function in the ‘Seguimiento Universidad de Navarra’ (SUN) Project, a Spanish prospective cohort study. Changes (final – initial) in cognitive function were evaluated in a subsample of 806 participants (mean age 66 (sd 5) years, 69·7 % male) of the SUN Project using the validated Spanish Telephone Interview for Cognitive Status-modified score. Polyphenol intake was derived from a validated semi-quantitative FFQ and matching food composition data from the Phenol-Explorer database. Multivariable linear regression models were used to evaluate the association between total polyphenol intake, polyphenol subclasses and cognitive changes. No significant association between total polyphenol intake and changes in cognitive function was found. However, a higher intake of lignans (βQuintile (Q) 5 v. Q1 0·81; 95 % CI 0·12, 1·51; Ptrend = 0·020) and stilbenes (βQ5 v. Q1 0·82; 95 % CI 0·15, 1·49; Ptrend = 0·028) was associated with more favourable changes in cognitive function over time, particularly with respect to immediate memory and language domains. Olive oil and nuts were the major sources of variability in lignan intake, and wine in stilbene intake. The results suggest that lignan and stilbene intake was associated with improvements in cognitive function.

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