Effects of Polymorphic Milk Protein Genes on Milk Yield and Composition Traits in Holstein Cattle

1992 ◽  
Vol 42 (1) ◽  
pp. 1-7 ◽  
Author(s):  
I. L. Mao ◽  
L. G. Buttazzoni ◽  
R. Aleandri
Keyword(s):  
Milk Yield ◽  
Milk Protein ◽  
Holstein Cattle ◽  
Milk Protein Genes

Молочная продуктивность коров австралийской селекции разной линейной принадлежности

2019 ◽  
pp. 27-31 ◽  
Author(s):  
I.F. GORLOV ◽  
E.YU. ZLOBINA ◽  
A.A. KAIDULINA ◽  
T.N. BARMINA ◽  
S.A. SURKOVA ◽  
...  
Keyword(s):  
Milk Production ◽  
Milk Yield ◽  
Milk Fat ◽  
Mass Fraction ◽  
Milk Protein ◽  
Holstein Cattle ◽  
Volgograd Region ◽  
Ideal Line ◽  
Calcium And Phosphorus ◽  
Selection Of

Приведены результаты исследований молочной продуктивности и качественных показателей молока коров голштинской породы австралийской селекции 3 линий в условиях Волгоградской области. Установлено, что наиболее высокий удой молока по 1й лактации был у коров линии Рефлекшн Соверинга 198998 7262,0 кг. В сравнении со сверстницами линий Вис Бэк Айдиала 1013415 и Монтвик Чифтейна 95679 он был выше, соответственно, на 84,3 и 351,1 кг. Лучший показатель содержания жира установлен в молоке коров линии Монтвик Чифтейна 95679 3,90. Валовой выход жира был больше у коров линии Рефлекшн Соверинга 198998 в сравнении со сверстницами линий Вис Бэк Айдиала 1013415 и Монтвик Чифтейна 95679 на 4,15 и 11,42 кг. Они же отличались и наибольшим выходом молочного белка.По наивысшей лактации бльшим удоем отличались коровы линии Вис Бэк Айдиала 1013415 7689,65 кг, которые превосходили по данному показателю сверстниц линии Рефлекшн Соверинга 198998 и Монтвик Чифтейна 95679, соответственно, на 134,5 и 252,17 кг. От них молочного жира было получено больше в сравнении со сверстницами линий Рефлекшн Соверинга 198998 и Монтвик Чифтейна 95679, соответственно, на 4,42 и 9,65 кг, массовая доля белка в молоке коров этой линии была выше, соответственно, на 4,12 и 7,42 кг. Казеина содержалось больше в молоке коров линии Вис Бэк Айдиала 1013415 по сравнению со сверстницами линий Рефлекшн Соверинга 198998 и Монтвик Чифтейна 95679 на 0,02 и 0,05, продолжительность сычужной свертываемости молока у них была короче, соответственно, на 1,40 и 1,15 мин. Содержание кальция и фосфора в молоке анализируемых линий находилось в пределах физиологической нормы. Целесообразно и перспективно более широкое использование животных линий Вис Бэк Айдиала 1013415 и Рефлекшн Соверинга 198998.The article presents the results of studies of milk production and quality indicators of milk of cows of the Australian selection of Holstein cattle of three lines in the conditions of the Volgograd region. It was established that the highest milk yield in the first lactation was in cows of the Reflection Sovering line 198,998 7,262.0 kg. In comparison with the peers of the lines of Vis Back Ideal 1013415 and Montwick Chieftain 95679, it was higher by 84.3 and 351.1 kg, respectively. The best indicator of fat content is set in the milk of cows of the Montwick Chieftain line 95679 3.90. The gross yield of fat was greater for cows in the Reflection Line of Sovering 198998 compared with the peers of the lines of Vis Back Ideal 1013415 and Montwick Chieftain 95679 by 4.15 and 11.42 kg. They also differed in the highest yield of milk protein. In terms of the highest lactation, the cows of the Vis Back Ideal line 1013415 7689.65 kg differed in terms of high milk yield, which surpassed in this indicator the contemporaries of the Reflection Sovering line 198998 and Montwick Chieftain 95679, respectively, by 134.5 and 252.17 kg. Milk fat was obtained from them in comparison with the peers of the Reflection Sovering lines 198998 and Montwick Chieftain 95679 by 4.42 and 9.65 kg, respectively, the mass fraction of protein in the milk of cows of this line was higher respectively by 4.12 and 7.42 kg. There was more casein in milk of cows of the Vis Back Ideal line 1013415 compared to the peers of Reflection Sovering 198998 and Montwick Chieftain 95679 peers by 0.02 and 0.05, the duration of rennet coagulability of milk was shorter by 1.40 and 1.15, respectively min The content of calcium and phosphorus in the milk of the analyzed lines was within the physiological norm.Consequently, it is expedient and promising to use the animal lines of the Vis Back Ideal 1013415 and Reflection Sovering 198998.

scholarly journals Mapping and analysis of dairy cattle quantitative trait loci by maximum likelihood methodology using milk protein genes as genetic markers.

Genetics ◽  
1994 ◽  
Vol 137 (1) ◽  
pp. 267-280 ◽  
Author(s):  
H Bovenhuis ◽  
J I Weller
Keyword(s):  
Maximum Likelihood ◽  
Dairy Cattle ◽  
Milk Yield ◽  
Quantitative Trait ◽  
Milk Protein ◽  
Direct Effects ◽  
Milk Protein Genes ◽  
Beta Casein ◽  
Fat Yield ◽  
Beta Lactoglobulin

Abstract Maximum likelihood methodology was used to estimate effects of both a marker gene and a linked quantitative trait locus (QTL) on quantitative traits in a segregating population. Two alleles were assumed for the QTL. In addition to the effects of genotypes at both loci on the mean of the quantitative trait, recombination frequency between the loci, frequency of the QTL alleles and the residual standard deviation were also estimated. Thus six parameters were estimated in addition to the marker genotype means. The statistical model was tested on simulated data, and used to estimate direct and linked effects of the milk protein genes, beta-lactoglobulin, kappa-casein, and beta-casein, on milk, fat, and protein production and fat and protein percent in the Dutch dairy cattle population. beta-Lactoglobulin had significant direct effects on milk yield and fat percent. kappa-Casein had significant direct effects on milk yield, protein percent and fat yield. beta-Casein had significant direct effects on milk yield, fat and protein percent and fat and protein yield. Linked QTL with significant effects on fat percent were found for kappa-casein and beta-casein. Since the beta-casein and kappa-casein genes are closely linked, it is likely that the same QTL was detected for those two markers. Further, a QTL with a significant effect on fat yield was found to be linked to kappa-casein and a QTL with a significant effect on protein yield was linked to beta-lactoglobulin.

scholarly journals Relationships between milk protein polymorphisms and production traits in cattle: a systematic review and meta-analysis

2018 ◽  
Vol 61 (2) ◽  
pp. 197-206 ◽  
Author(s):  
Memis Ozdemir ◽  
Sinan Kopuzlu ◽  
Mehmet Topal ◽  
Omer Cevdet Bilgin
Keyword(s):  
Protein Content ◽  
Milk Yield ◽  
Milk Protein ◽  
Meta Analysis ◽  
Fat Content ◽  
Production Traits ◽  
Milk Protein Genes ◽  
Fat Yield ◽  
Daily Milk Yield ◽  
Daily Milk

Abstract. Many researchers who have studied the relationships between milk protein polymorphisms and some yield traits in dairy cattle have reported incompatible results. In this study, in order to examine the overall relationships between milk protein genes known as major genes (CSN1S1, CSN2, CSN3, and BLG) and some yield traits (daily milk yield, lactation milk yield, fat yield, fat content, protein yield, and protein content), a meta-analysis was performed using some genetic models reported in the results of previous studies on cattle. The results suggest that the relationships of major milk protein genes with other factors should be studied using the codominant genetic model in general. Relationships among some CSN3 genotypes and fat yield, fat content, and protein content, and relationships between some BLG genotypes and daily milk yield, fat content, protein yield, and protein content were significant (P<0.05). No significant (P>0.05) relationships were found between these genotypes and other milk production traits. In addition, no significant (P>0.05) relationships between the CSN1S1 and CSN2 genotypes with the milk production traits examined were observed.

scholarly journals Associations between <i>paratuberculosis</i> status and milk production traits in Holstein cattle under consideration of interaction effects between test result and farm and lactation number

2013 ◽  
Vol 56 (1) ◽  
pp. 924-933 ◽  
Author(s):  
J. Küpper ◽  
H. Brandt ◽  
K. Donat ◽  
G. Erhardt
Keyword(s):  
Milk Yield ◽  
Milk Fat ◽  
Milk Protein ◽  
Economic Losses ◽  
Holstein Cattle ◽  
Calving Interval ◽  
Production Traits ◽  
Milk Production Traits ◽  
Faecal Culture ◽  
Test Result

Abstract. One of the most important factors for economic losses as result of infection with Mycobacterium avium ssp. paratuberculosis (MAP) is the decrease in milk yield. Different phenotyping methods for MAP lead to an inconsistent impact of MAP infection on milk parameters. It was the aim of the study to analyse the effect of the MAP status on milk yield, milk fat and milk protein (in kilograms), as well as on the calving interval and milk kilograms per day of life in German Holstein cattle. A dataset of 9 367 faecal culture tested animals from 14 farms in Thuringia (Germany) were available. The MAP status of the animals affected milk yield and the milk parameters. Beside the effects of farm, lactation number and MAP status, the interaction between MAP status and farm on the milk parameters was significant. The latter result is a possible explanation for the inconsistent results from recent studies. For milk kg per day of life, the interaction between lactation number and MAP status also showed significance.

Association of milk protein genes with fertilization rate and early embryonic development in Holstein dairy cattle

2011 ◽  
Vol 79 (1) ◽  
pp. 47-52 ◽  
Author(s):  
Francisco Peñagaricano ◽  
Hasan Khatib
Keyword(s):  
Embryonic Development ◽  
Dairy Cattle ◽  
Whey Protein ◽  
Milk Yield ◽  
Milk Protein ◽  
Fertilization Rate ◽  
Early Embryonic Development ◽  
Milk Protein Genes ◽  
Fertility Traits

Concomitant with intensive selection for increased milk yield, reproductive performance of dairy cows has declined in the last decades, in part due to an unfavourable genetic relationship between these traits. Given that the six main milk protein genes (i.e. whey proteins and caseins) are directly involved in milk production and hence have been a target of the strong selection aimed at improving milk yield in dairy cattle, we hypothesized that these genes could show selection footprints associated with fertility traits. In this study, we used an in-vitro fertilization (IVF) system to test genetic association between 66 single nucleotide polymorphisms (SNPs) in the four caseins (αS1-casein, αS2-casein, β-casein and κ-casein) and the two whey protein genes (α-lactalbumin and β-lactoglobulin) with fertilization rate and early embryonic development in the Holstein breed. A total of 6893 in-vitro fertilizations were performed and a total of 4661 IVF embryos were produced using oocytes from 399 ovaries and semen samples from 12 bulls. Associations between SNPs and fertility traits were analysed using a mixed linear model with genotype as fixed effect and ovary and bull as random effects. A multiple testing correction approach was used to account for the correlation between SNPs due to linkage disequilibrium. After correction, polymorphisms in the LALBA and LGB genes showed significant associations with fertilization success and blastocyst rate. No significant associations were detected between SNPs located in the casein region and IVF fertility traits. Although the molecular mechanisms underlying the association between whey protein genes and fertility have not yet been characterized, this study provides the first evidence of association between these genes and fertility traits. Furthermore, these results could shed light on the antagonistic relationship that exists between milk yield and fertility in dairy cattle.

REALIZATION OF PARENTAL INDICES OF COW PRODUCTIVITY IN DIFFERENT MILKING BREEDS AT BREEDING FARM "AGROFIRMA "PAKHMA"

2020 ◽  
Keyword(s):  
Milk Yield ◽  
Cattle Breed ◽  
Holstein Cattle ◽  
Milk Productivity ◽  
Cattle Breeds ◽  
Significant Difference ◽  
Production Indices ◽  
High Level ◽  
Beta Lactoglobulin ◽  
Percentage Protein

Combination of genotypes of main types’ genetic markers causes milk productivity in cattle. The article studies correlation between kappa casein genotypes (C3N3), beta-lactoglobulin (LGB), their complexes and milk production indices in cows bred under equal conditions at a breeding farm. The calculation of parental milk yield and fat indices between the three breeds showed a significant difference (P>0,999) of PCI of Ayrshire and Holstein cattle breed milk yield - 3395 kg, PCI of fat - 0,22%; between Holstein and Yaroslavl cattle breeds - 3200 kg, PCI offat - 0,16%. A significant difference of realization indices of protein between all three breeds was not stated. The highest realization ofparental milk yield index was stated - between Ayrshire and Yaroslavl cattle breeds- 113%, Holstein cattle breed - 88%. As for the fat and protein indices, all three cattle breeds showed a high realization of PCI from 98% to 109%. However, Holstein cattle breed showed the highest percentage: protein - 101%, fat - 109%. A significant difference of PCI realization of milk productivity in CSN3 and LGB genotypes was not stated. It was also stated that there is a tendency of high level parental indices realization when there is a higher number of B-allele variants in genotypes of cows.

The effect of oral calcium boluses at parturition on blood metabolites and milk yield in grazing Holstein cattle

2021 ◽  
pp. 104510
Author(s):  
Pedro Melendez ◽  
Carlos Roeschmann ◽  
Alejandra Arevalo ◽  
Jan Moller
Keyword(s):  
Milk Yield ◽  
Blood Metabolites ◽  
Holstein Cattle ◽  
Oral Calcium

scholarly journals Multiple Effects of Genetic Background on Variegated Transgene Expression in Mice

Genetics ◽  
2002 ◽  
Vol 160 (3) ◽  
pp. 1107-1112
Author(s):  
Margaret L Opsahl ◽  
Margaret McClenaghan ◽  
Anthea Springbett ◽  
Sarah Reid ◽  
Richard Lathe ◽  
...  
Keyword(s):  
Transgene Expression ◽  
Milk Protein ◽  
Position Effect ◽  
Position Effect Variegation ◽  
Parental Population ◽  
Expression Levels ◽  
Variable Expression ◽  
Specific Effects ◽  
Milk Protein Genes ◽  
Β Lactoglobulin

Abstract BLG/7 transgenic mice express an ovine β-lactoglobulin transgene during lactation. Unusually, transgene expression levels in milk differ between siblings. This variable expression is due to variegated transgene expression in the mammary gland and is reminiscent of position-effect variegation. The BLG/7 line was created and maintained on a mixed CBA × C57BL/6 background. We have investigated the effect on transgene expression of backcrossing for 13 generations into these backgrounds. Variable transgene expression was observed in all populations examined, confirming that it is an inherent property of the transgene array at its site of integration. There were also strain-specific effects on transgene expression that appear to be independent of the inherent variegation. The transgene, compared to endogenous milk protein genes, is specifically susceptible to inbreeding depression. Outcrossing restored transgene expression levels to that of the parental population; thus suppression was not inherited. Finally, no generation-dependent decrease in mean expression levels was observed in the parental population. Thus, although the BLG/7 transgene is expressed in a variegated manner, there was no generation-associated accumulated silencing of transgene expression.

INFLUENCE OF AMMONIATION OF, HIGH-MOISTURE BARLEY ON DIGESTIBILITY, KINETICS OF RUMEN INGESTA TURNOVER, AND MILK PRODUCTION IN DAIRY COWS

1989 ◽  
Vol 69 (1) ◽  
pp. 195-203 ◽  
Author(s):  
P. H. ROBINSON ◽  
J. J. KENNELLY
Keyword(s):  
Dairy Cows ◽  
Milk Yield ◽  
Dry Matter ◽  
Milk Protein ◽  
Energetic Efficiency ◽  
Vitamin Supplement ◽  
High Moisture ◽  
Key Words Barley ◽  
Kinetics Of ◽  
Pool Sizes

Three dairy cows with large rumen cannulae were fed totally mixed diets twice daily. Diets contained 49% whole crop oat silage, 38.5% high-moisture barley (HMB), and 12.5% protein-mineral-vitamin supplement on a dry matter (DM) basis. HMB had been ammoniated at target levels of 0, 0.65, 1.30, and 1.95 g per 100 g HMB DM. Actual levels achieved were 0, 0.63, 1.30, and 1.95 g ammonia per 100 g. Apparent digestibility of organic matter (OM), neutral detergent (ND) fiber, starch, and N were not significantly influenced by level of ammoniation of HMB, although there was a trend for increased N digestion. Total rumen pool sizes of wet ingesta and DM were not influenced by ammoniation levels of HMB, although proportion of ND fiber in rumen OM declined as level of ammoniation of HMB increased. Milk yield and production of milk protein and lactose increased as level of ammoniation of HMB increased. Data are interpreted to suggest that rumen digestion of dietary nonfiber components declined as level of ammoniation of HMB increased, although digestion of ND fiber was not influenced. These results support the hypothesis that ammoniation of HMB shifted the site of digestion of a portion of the dietary nonfiber component from the rumen to the intestine without influencing rumen microbial pool sizes or degradative activity. Greater energetic efficiency of intestinal digestion of dietary nonfiber components, as level of ammoniation of HMB increased, may have contributed to the increased milk yield. Key words: Barley (high-moisture), ammoniation, dairy cows, digestion

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