Differences in Antimicrobial Susceptibility Among Hospitals in an Integrated Health System

2001 ◽  
Vol 22 (6) ◽  
pp. 379-382 ◽  
Author(s):  
Teresa J. Lubowski ◽  
John L. Woon ◽  
Patricia Hogan ◽  
Ching-Chang Hwang
Keyword(s):  
Health System ◽  
Health Systems ◽  
Antimicrobial Susceptibility ◽  
Antibiotic Susceptibility ◽  
Healthcare Systems ◽  
Integrated Healthcare ◽  
Susceptibility Data ◽  
Integrated Health ◽  
Susceptibility Patterns

AbstractWe evaluated the differences in antimicrobial susceptibility among hospitals in three different integrated healthcare systems. Each system provided antibiogram-susceptibility reports from representative hospitals. Reports were analyzed for statistically significant differences between hospitals in a given system for nine important organisms. We found numerous significant interhospital differences in antimicrobial-susceptibility patterns within health systems. For this reason, the practice of combining antibiotic-susceptibility data into a systemwide antibiogram should be discouraged.

Antibiotic Susceptibility Patterns of Yersinia enterocolitica

1981 ◽  
Vol 44 (2) ◽  
pp. 124-127 ◽  
Author(s):  
L. RESTAINO ◽  
W. M. HILL
Keyword(s):  
Yersinia Enterocolitica ◽  
Antimicrobial Susceptibility ◽  
Antibiotic Susceptibility ◽  
Penicillin G ◽  
Susceptibility Pattern ◽  
Antimicrobial Susceptibility Pattern ◽  
Resistance To Penicillin ◽  
Antibiotic Susceptibility Patterns ◽  
Susceptibility Patterns

Antibiotic susceptibility patterns for Yersinia enterocolitica strains involving 10 different serotypes were analyzed and compared. All Y. enterocolitica were susceptible to colistin, gentamicin, kanamycin, neomycin and doxycycline, whereas all isolates displayed resistance to penicillin G, methicillin (derivative of penicillin), novobiocin, and clindamycin. The antibiograms for the Y. enterocolitica isolates were in some instances related to the somatic serotypes, especially serotype 0:8 for which the antimicrobial susceptibility pattern displayed the greatest disparity. By eliminating the antibiograms for the four serotype 0:8 strains, antimicrobial susceptibility patterns for atypical and typical strains were similar.

scholarly journals Frequency and antibiotic susceptibility patterns of urinary pathogens in male outpatients in Argentina

2014 ◽  
Vol 8 (06) ◽  
pp. 699-704 ◽  
Author(s):  
Hugo E Villar ◽  
Mónica B Jugo ◽  
Alejandro Macan ◽  
Matias Visser ◽  
Mariana Hidalgo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Adult Male ◽  
Antimicrobial Susceptibility ◽  
Antibiotic Susceptibility ◽  
Urine Samples ◽  
Diffusion Method ◽  
Bacterial Strains ◽  
Gram Negative ◽  
Antibiotic Susceptibility Patterns ◽  
Susceptibility Patterns

Introduction: Knowledge of the etiology and antimicrobial susceptibility patterns of uropathogens is important for determining the best treatment option. This study aimed to determine the distribution and antibiotic susceptibility patterns of bacterial strains isolated from adult male outpatients. Methodology: Between November 2012 and April 2013, 3,105 community urine samples were analyzed from adult male patients who attended the Laboratorio Hidalgo, Buenos Aires, Argentina. Antimicrobial susceptibility testing was performed by the Kirby-Bauer disc diffusion method. Isolates resistant to third generation cephalosporin were tested for extended-spectrum beta-lactamase (ESBL) production using the double-disk synergy test. Results: Of the 3,105 urine samples analyzed, 791 (25.5%) had significant bacteriuria. The frequency of positive urine cultures increased significantly with patient age. Escherichia coli was isolated most frequently (47.3%), followed by Enterococcus faecalis (13.6%), and Klebsiella pneumoniae (11.9%). Gram-negative organisms represented 78.8% of urinary pathogens. The highest activities against Gram-negative bacteria were found with imipenem (99.0%), amikacin (98.1%), ertapenem (94.2%), fosfomycin (90.7%), and piperacillin-tazobactam (90.1%). The frequencies of ESBLs among E. coli, K. pneumoniae, and P. mirabilis were 15.2 %, 22.3%, and 8%, respectively. Fosfomycin, piperacillin-tazobactam, and nitrofurantoin were most effective against Gram-positive organisms. Conclusions: Fosfomycin may be an excellent option for cystitis treatment in patients without risk factors, whereas piperacillin-tazobactam is preferred for the treatment of parenchymatous UTIs, complicated UTIs, and UTIs associated with risk factors. To ensure the optimal selection of antibiotics, physicians should have access to up-to-date information about the local prevalence of antimicrobial resistance.

scholarly journals First data on antimicrobial susceptibility patterns of Moraxella catarrhalis isolates in Lebanon

10.3823/833 ◽  
2019 ◽  
Vol 9 (2) ◽  
Author(s):  
Monzer Hamze ◽  
Marwan Osman ◽  
Hassan Mallat ◽  
Marcel El Achkar
Keyword(s):  
Nalidixic Acid ◽  
Antimicrobial Susceptibility ◽  
Moraxella Catarrhalis ◽  
Antibiotic Susceptibility ◽  
Bacterial Pathogen ◽  
Diagnostic Tools ◽  
Flight Mass Spectrometry ◽  
High Level ◽  
Susceptibility Profiles ◽  
Susceptibility Patterns

Background. Moraxella catarrhalis is an important bacterial pathogen. Although national data have shown an increase in the levels of antimicrobial resistance in clinical settings in Lebanon, there is a lack of data regarding this human pathogen. This study aimed to determine for the first time the antimicrobial susceptibility profiles of M. catarrhalis isolates in Lebanon. Methods. A total of 34 M. catarrhalis strains were isolated from clinical specimens during the period from November 2010 to March 2019. Bacterial identification was carried out using matrix assisted laser desorption ionization–time of flight mass spectrometry. Antibiotic susceptibility of all isolates was performed according the recommendations of the European Committee on Antimicrobial Susceptibility Testing (EUCAST). Results. A total of 34 non-duplicated M. catarrhalis strains were isolated from nose (n=19), ear (n=7), sputum (n=5), blood (n=1), eye (n=1), and throat (n=1) of patients referred to Nini Hospital in Tripoli, North governorate of Lebanon. Regarding antibiotic susceptibility rates, the percent susceptibility is 100% to the majority of antibiotics, except ampicillin (7.4%), trimethoprim-sulfamethoxazole (85.3%), nalidixic acid (85.3%), and ciprofloxacin (97.1%). Conclusion. To our knowledge, this study is the first investigation regarding the antimicrobial susceptibility patterns of M. catarrhalis isolates in Lebanon. In addition to the high level of resistance to ampicillin, our findings showed the emergence of resistance to trimethoprim-sulfamethoxazole, nalidixic acid and ciprofloxacin. Even if this study provides useful information to develop effective empirical treatment, we recommend the implementation of reliable diagnostic tools to guide appropriate treatment.

scholarly journals The practice of integrated healthcare and the experiences of people in Ghana’s Ashanti region

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Irene G. Ampomah ◽  
Bunmi S. Malau-Aduli ◽  
Abdul-Aziz Seidu ◽  
Aduli E. O. Malau-Aduli ◽  
Theophilus I. Emeto
Keyword(s):  
Health Services ◽  
Health System ◽  
National Health System ◽  
Integrated System ◽  
Service Users ◽  
Integrated Healthcare ◽  
Ashanti Region ◽  
Services Delivery ◽  
Satisfactory Outcome ◽  
Integrated Health

Abstract Background The Ghanaian government has implemented interventions that integrate traditional medicine (TM) into its national health system in response to the high prevalence of TM use. However, empirical evidence of the experiences of service users and the practice of integrated health in Ghana is scanty. Therefore, this study explored the experiences of people with TM integration into the formal health system in Ashanti region using an adapted TM integration framework. Methods A sequential explanatory mixed methods study design comprising survey administration and in-depth interviews for data collection was utilised to address the research objective. Framework analysis was used in analysing the qualitative data and for triangulation of results. Results Participants were aware of licensing and training of TM practitioners in a science-based university in Ghana. However, knowledge of the existence of TM units in selected hospitals in the region was minimal. Integration knowledge was largely influenced by sex, marital status, household size and residential status, where males and urban dwellers were more familiar with the process than females and rural dwellers. Low patronage of integrated health services in the region was attributable to weak cross referrals. However, service users who had engaged with the integrated system recounted a satisfactory outcome. Conclusion Service users’ unfamiliarity with the presence of integrated facilities in Ghana could be an impediment to the practice of integrated healthcare. Sensitisation of the public about the practice of an integrated system could refine the Ghanaian integrated system. Regular evaluation of patient satisfaction and outcome measures might also serve as an effective strategy for improving health services delivery since evaluation is becoming an important component of health service design and implementation. There is the need for future studies to focus on exploring the perceptions and experiences of health practitioners and hospital administrators regarding the practice of integrated health in Ghana.

DESIGNING AN INTEGRATED HEALTH CARE STRATEGY

2020 ◽  
Vol 21 (1) ◽  
pp. 65-76
Author(s):  
Małgorzata Dymyt
Keyword(s):  
Health Care ◽  
Health Services ◽  
Health Systems ◽  
Health Sector ◽  
Integrated Health Care ◽  
Integrated Healthcare ◽  
Care Integration ◽  
Integrated Health ◽  
Key Aspects ◽  
Delivery Of Health Services

The article concerns the strategic dimension of the integration of health care. The concept of integrated health care plays a key role in the improvement of health systems. The complexity of the health care system makes a coherent, comprehensive and coordinated approach to health services necessary. The integration of health care consists in the management and delivery of health services in such a way that patients receive continuity of health care, coordinated at various levels, within and outside the health sector and as needed throughout their lives. The purpose of the article is to present the essence of health care integration and key aspects of the design of integrated healthcare strategy, identify its assumptions and main elements.

scholarly journals Effectiveness of Integrated Health Systems in Africa: A Systematic Review

Medicina ◽  
2020 ◽  
Vol 56 (6) ◽  
pp. 271
Author(s):  
Irene G. Ampomah ◽  
Bunmi S. Malau-Aduli ◽  
Aduli E.O. Malau-Aduli ◽  
Theophilus I. Emeto
Keyword(s):  
Health System ◽  
Quality Assessment ◽  
Health Systems ◽  
Assessment Tool ◽  
Integrated System ◽  
Health Policies ◽  
Orthodox Medicine ◽  
Ovid Medline ◽  
Integrated Health ◽  
Critical Appraisal Tool

Background and objective: Traditional medicine (TM) was integrated into health systems in Africa due to its importance within the health delivery setup in fostering increased health care accessibility through safe practices. However, the quality of integrated health systems in Africa has not been assessed since its implementation. The objective of this paper was to extensively and systematically review the effectiveness of integrated health systems in Africa. Materials and Methods: A systematic literature search was conducted from October, 2019 to March, 2020 using Ovid Medline, Scopus, Emcare, Web of Science, Cumulative Index to Nursing and Allied Health (CINAHL), and Google Scholar, in order to retrieve original articles evaluating the integration of TM into health systems in Africa. A quality assessment of relevant articles was also carried out using the Quality Assessment Tool for Studies with Diverse Designs (QATDSS) critical appraisal tool. Results: The results indicated that the formulation and execution of health policies were the main measures taken to integrate TM into health systems in Africa. The review also highlighted relatively low levels of awareness, usage, satisfaction, and acceptance of integrated health systems among the populace. Knowledge about the existence of an integrated system varied among study participants, while satisfaction and acceptance were low among orthodox medicine practitioners. Health service users’ satisfaction and acceptance of the practice of an integrated health system were high in the countries assessed. Conclusion: The review concluded that existing health policies in Africa are not working, so the integration of TM has not been successful. It is critical to uncover the barriers in the health system by exploring the perceptions and experiences of stakeholders, in order to develop solutions for better integration of the two health systems.

Application of a Bioinformatics Method on Detecting of Acinetobacter baumannii Carrying Metallo-β-Lactamases Isolated from Inpatients

2014 ◽  
Vol 881-883 ◽  
pp. 335-338
Author(s):  
Lin Lin Ma ◽  
Ali Huang ◽  
Wei Chu ◽  
Xiao Han Li ◽  
Ming Cheng Li
Keyword(s):  
Acinetobacter Baumannii ◽  
Antimicrobial Susceptibility ◽  
Potential Risk ◽  
Gel Electrophoresis ◽  
Antibiotic Susceptibility ◽  
Screening Method ◽  
Pulsed Field Gel Electrophoresis ◽  
Plasmid Analysis ◽  
Antibiotic Susceptibility Test ◽  
Susceptibility Patterns

The aim of the study was to investigate the prevalence and charateristics of Acinetobacter baumannii producing MBLs isolated from the several wards of the affiliated hospital in Jilin regions. The bioinformatics technology was used to design primers, sequence and blast, in conjunction with antibiotic susceptibility test and MBL screening method. The total of 119 were isolated from three wards and 88 strains (73.9 %) produced MBLs, the number of 31 strains (26.1%) didnt produce MBLs. All MBLs isolates showed same antimicrobial susceptibility patterns. Among Acinetobacter baumannii producing MBLs, 78 strains (88.9%) were positive for blaOXA-23 gene, 10 strains (11.1%) contained blaVIM-2 gene. Plasmid profiles and pulsed-field gel electrophoresis were used to study the relatedness of isolates. All MBLs isolates were closely related by PFGE and plasmid analysis. This study confirmed the potential risk of spreading of Acinetobacter baumannii producing MBLs with inter-and intrahospital clonal transfer of patients.

scholarly journals Comparison of respiratory pathogen colonization and antimicrobial susceptibility in people with cystic fibrosis bronchiectasis versus non-cystic fibrosis bronchiectasis: a protocol for a systematic review

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Salony Verma ◽  
Joseph L. Mathew ◽  
Pallab Ray
Keyword(s):  
Systematic Review ◽  
Cystic Fibrosis ◽  
Respiratory Tract ◽  
Antimicrobial Susceptibility ◽  
Antibiotic Susceptibility ◽  
Bacterial Colonization ◽  
Respiratory Pathogen ◽  
Cochrane Library ◽  
The Impact ◽  
Susceptibility Patterns

Abstract Background Both cystic fibrosis (CF) and non-cystic fibrosis bronchiectasis are characterized by permanent bronchial dilation, impaired mucociliary clearance, and development of chronic colonization and infection. Although the major airway microbiota in both CF and non-CF bronchiectasis may be similar, there are some differences in clinical and microbiologic features. There may also be differences in antibiotic susceptibility patterns between the CF and non-CF populations. Therefore, analysis and comparison of the microbiota and antibiotic susceptibility pattern in CF bronchiectasis versus non-CF bronchiectasis would help to improve the management of both conditions. Methods Two authors will independently search the electronic databases PubMed, EMBASE, the Cochrane Library, and LIVIVO, for studies reporting bacterial colonization of the respiratory tract in adults and children diagnosed with bronchiectasis in either CF or non-CF. We will include studies examining any respiratory tract specimen, using conventional bacterial culture or other specialized techniques such as molecular methods. We will also examine the antimicrobial susceptibility patterns in people with CF bronchiectasis versus non-CF bronchiectasis. The authors will independently assess the risk of bias in each included study using the Newcastle Ottawa Scale (NOS). We will present the data with descriptive statistics and provide pooled estimates of outcomes, wherever it is feasible to perform meta-analysis. Heterogeneity in studies will be explored by visual inspection of forest plots as well as using the Higgins and Thompson I2 method. We will contact the corresponding authors of studies where data is/are missing and try to obtain the missing data. We will undertake sensitivity analysis to explore the impact of study quality and subgroup analysis based on pre-set criteria. We will prepare a summary of findings’ table and assess the confidence in the evidence using the GRADE methodology. Discussion To date, there are no locally applicable evidence-based guidelines for antimicrobial treatment of non-CF bronchiectasis patients. In general, treatment is based on extrapolation of evidence in people with CF bronchiectasis. An insight into the microbiota and antimicrobial susceptibility patterns in the two conditions would facilitate appropriate rather than empiric antimicrobial therapy and hopefully reduce the burden of antimicrobial resistance created by rampant usage of antibiotics. Systematic review registration The protocol has been registered in PROSPERO on July 26, 2020 (PROSPERO registration number: CRD42020193859).

scholarly journals Recent Antimicrobial Susceptibility Patterns of Salmonella Isolates in A Tertiay Care Hospital Lahore

Esculapio ◽  
2021 ◽  
Vol 17 (1) ◽  
pp. 45-48
Author(s):  
Hina Bukhari ◽  
Tayyeba Komal ◽  
Raana Akhtar ◽  
Sami Ullah Mumtaz ◽  
Iqra Waheed
Keyword(s):  
Antimicrobial Susceptibility ◽  
Antibiotic Susceptibility ◽  
Clinical Laboratory ◽  
Tertiary Care ◽  
Salmonella Typhi ◽  
Multidrug Resistant ◽  
Care Hospital ◽  
Cross Sectional ◽  
Sensitivity Pattern ◽  
Susceptibility Patterns

Objective: To determine the recent antimicrobial susceptibility patterns of salmonella isolates (typhi and paratyphi) in a tertiary care hospital of Lahore. Methods: It is cross sectional retrospective study conducted out in King Edward Medical University(Pathology deptt)/Mayo Hospital Lahore.The study period is six months from May 2019 to October 2019(Peak months of Typhoid fever).During this six months study period, total of 4284 samples for blood culture were received that were inoculated on the macConkey and blood agar plates.The growths obtained were then processed through biochemical profiling and analytical profile index(API).The Kirby Bauer technique was used for antibiotic susceptibility testing and reporting was done on the basis of clinical laboratory standard institute(CLSI). Results: During these six months, total 4284 blood samples were inoculated, out of which 433 growths were obtained. There were 84 strains of salmonella typhi isolated. Sensitivity pattern of different antibiotics showed that Azithromycin was sensitive to 70 (83.3%) isolates, imipenem in 72 (85.7%), ciprofloxacin to 56 (66.7%), gentamycin to 48 (57.1%), ceftriaxone to 45 (53.6%), cefepime to 20 (23.8%), chloramphenicol to 12 (14.3%) while ampicillin was least sensitive i.e. 8 (9.5%) isolates. There were 24 MDR(multidrug resistant) and 12 were XDR(extensive drug resistant) strains. We also found out that resistance to azithromycin drug is also emerging as 70 out of 84 strains were sensitive while remaining 14 were resistant. Conclusion: According to recent antibiotic susceptibility against salmonella typhi, the most sensitive drugs are Carbapenems (imipenem or meropenem) these days. Second sensitive antibiotic is azithromycin. Key Words: Antimicrobial susceptibility, Salmonella isolates, Carbapenems, Azithromycin. How to cite: Bukhari H., Komal T., Akhtar R., Mumtaz U.S., Waheed I., Recent Antimicrobial Susceptibility Patterns of Salmonella Isolates in A Tertiay Care Hospital of Lahore. Esculapio 2021;17(01):45-48

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