scholarly journals Assessment of physiological and biochemical indicators of the state of the so-iuy mullet Liza haematocheilus (Temminck & Shlegel, 1845) in the Azov-Black Sea Basin

2021 ◽  
Vol 937 (2) ◽  
pp. 022063
Author(s):  
Olga Kirichenko ◽  
Leonid Bugaev ◽  
Anna Voykina ◽  
Victoria Lisovskaya ◽  
Efim Kozhurin
Keyword(s):  
Feeding Rate ◽  
Physiological State ◽  
Comprehensive Analysis ◽  
Stress Effect ◽  
Normal Range ◽  
Fish Tissues ◽  
Total Blood ◽  
Spawning Period ◽  
Blood Serum Protein ◽  
Physiological And Biochemical

Abstract A comprehensive analysis of the physiological state of the so-iuy mullet, inhabiting the Sea of Azov, has been carried out during its pre-spawning period in 2020–2021. The hematological characteristics of the investigated individuals have been evaluated. It has been revealed that the content of protein and lipids in fish tissues was at the level of average longterm values. The content of protein and lipids in the gonads of females was significantly higher than that of males, which is explained by the forthcoming stage of spawning. It has been determined that the contribution of albumin to the total blood serum protein was minimal, which could be a consequence of the low feeding rate of the fish. At the same time, no stress effect was identified-glucose was within its normal range.

scholarly journals LEVEL OF MARKERS OF NEURODEGENERATION IN PATIENTS WITH OCULAR ISCHEMIC SYNDROME

2014 ◽  
Vol 7 (2) ◽  
Author(s):  
Halidjan Kamilov ◽  
Munirahon Kasimova ◽  
Dilbar Makhkamova
Keyword(s):  
Blood Serum ◽  
Protein S ◽  
Main Group ◽  
Tear Fluid ◽  
Control Group ◽  
Normal Range ◽  
Ocular Ischemic Syndrome ◽  
S 100 ◽  
Blood Serum Protein ◽  
Ischemic Syndrome

The purpose of this study was to investigate the content neurospecific markers protein S-100 and neuroenolaza in blood serum and tear fluid of patients with ocular ischemic syndrome.Material and methods. We observed 43 patients aged 57 to 79 years, mean age 67.3 ± 2.7 years. Control group consisted of 11 volunteers  without ophthalmic symptoms. The main group consisted of 32 patients with OIS. The neurospecific proteins S100 and NSE were investigated in blood serum and tear fluid.Results. The study found that in patients of the control group the content of protein were within the normal range: S- 100 in the tear fluid – 0,0662 ± 0,00335 mkg/l, in the blood serum 0,0508 ± 0,00241 mkg/l. In patients of the main group the indicators of protein in the tear fluid were elevated in all patients - 3,12 ± 0,246 mkg/l ( p<0.005). The normal levels in blood serum of marker S-100 was in 30 patients - 0,0589 ± 0,00303 mkg/l, while, in 2 patients protein S-100 were raised and averaged 0,2175±0,00725 mkg/l. It was found that in patients of the control group content of protein NSE in the tear fluid and blood serum were within normal values - 15,86 ± 0,148 Ng/ml, 15,60 ± 0,202 Ng/ml respectively. In the main group the amount of protein NSE tended to increase in the tear fluid in 23 patients and averaged 33,012 ± 3,2626 Ng/ml (p<0.005), a significant decrease the quantity of protein was observed in 9 patients, which amounted to 5,166 ± 0,8301 Ng/ml. At normal levels in the blood serum protein NSE detected in 30 patients and averaged 14,48 ± 0,263 Ng/ml, whereas, in 2 patients there was a significant increase of content of protein NSE and was 27,47 ± 3,068 Ng/ml.Conclusions. Thus, changes in the concentration of S100 and neuroenolaza in the tear fluid in patients with ocular ischemic syndrome allow to identify as marker of nerve cells damage of the eye, contributing to the definition in conjunction with other signs of stage and etiology of the disease.

scholarly journals Estimation of Sodium and Potassium in Dogs with Diarrhoea and Vomition

2013 ◽  
Vol 13 (2) ◽  
pp. 33-38
Author(s):  
Sulochana Shrestha ◽  
Mukti N Shrestha ◽  
Yugal R Bindari
Keyword(s):  
Potassium Level ◽  
Age Group ◽  
Normal Range ◽  
German Shepherd ◽  
Total Blood ◽  
Blood Samples ◽  
Test Kit ◽  
Lower Limits ◽  
Sodium And Potassium ◽  
Lower Limit Of Normal

The study was conducted to estimate the sodium and potassium level in dogs with diarrhea and vomition. Total 150 blood samples were collected and processed in the laboratory of Vet clinic, Krishnagalli as per the protocol of Elyte 2 test kit using colorimeter. Of the total blood samples, 8% showed normonatremia with normokalemia, 76% showed hyponatremia with hypokalemia and 16% showed hyponatremia with hyperkalemia. Diarrhoea and vomition were more prevalent in age group 0-1 years followed by more than 8 years and 1-8 years. The age group 0-1 and 1-8 years showed normonatremia with normokalemia and hyponatremia with hypokalemia but more than 8 years showed hyponatremia with hyperkalemia. Males were found more vulnerable for diarrhoea and vomition than the females. The estimated value of sodium and potassium in both sexes were obtained within normal to lower limits of normal range. German Shepherd had the higher prevalence of diarrhea and vomition among different breeds. The estimated value of sodium and potassium in different breeds showed modest difference and obtained within normal to lower limit of normal range. Na:K ratio was found less than 27:1 in 18% samples, between 27:1 to 40:1 in 26% samples and more than 40:1 in 56% samples. Nepal Journal of Science and Technology Vol. 13, No. 2 (2012) 33-38 DOI: http://dx.doi.org/10.3126/njst.v13i2.7711

scholarly journals AZATHIOPRINE INDUCED PANCYTOPENIA-A CASE REPORT

2017 ◽  
Vol 9 (2) ◽  
pp. 324 ◽  
Author(s):  
Jeslyn Mary Philip ◽  
Parvathypriya C. ◽  
Christeena George ◽  
Meenu Vijayan
Keyword(s):  
Optic Neuropathy ◽  
Tpmt Activity ◽  
Ischemic Optic Neuropathy ◽  
Normal Range ◽  
Total Blood ◽  
Oral Steroids ◽  
Low Levels ◽  
Severe Pancytopenia ◽  
Stimulating Factor

<p>Azathioprine (AZA), a prodrug of 6 mercaptopurine, is an immunosuppressant that can be used as adjunctive therapy with corticosteroids in the treatment of arteritic form of ischemic optic neuropathy. Although myelotoxicity is known to occur while using azathioprine, severe pancytopenia is rarely seen. Patients with thiopurine methyltransferase (TPMT) deficiency are at high risk of developing severe myelosuppression. A 63 year* old female with ischemic optic neuropathy was initiated treatment with oral methylprednisone. As two courses of oral steroids showed no significant improvement, oral azathioprine 25 mg twice daily was added and gradually increased to 50 mg twice daily with relief of symptoms. 6 mo later, she was admitted with acute stroke and lab reports showed low levels of total blood counts or pancytopenia. The patient was put on broad spectrum antibiotics; given injection of granulocyte colony stimulating factor 300 mcg subcutaneously and blood transfusion as correction till counts normalised. She improved over 14 d and on next follow-up counts were in normal range. Causality was assessed by Naranjo causality assessment scale and a probable relationship was obtained between azathioprine and pancytopenia with a score of 6. Variations in TPMT activity occurs due to genetic polymorphism. Physicians should be aware of the possibility of myelosuppression while prescribing azathioprine. Frequent blood count monitoring is the most convenient way to avoid this problem where testing for TPMT deficiency is not possible.</p>

DYNAMICS OF AN INTERIOR INDICATORS OF HOLSTEIN BREED HEIFERS AND THEIR MOTHERS IN THE TRANSITION LACTATION PERIOD

1970 ◽  
pp. 57-62
Author(s):  
G. G. Karlikova ◽  
R. А. Rykov
Keyword(s):  
Blood Serum ◽  
Total Bilirubin ◽  
High Energy ◽  
Blood Protein ◽  
Lactation Period ◽  
Normal Range ◽  
Total Blood ◽  
Upper Limit ◽  
Group 3 ◽  
Group 1

The article deals with a comparative analysis of biochemical and morphological parameters of blood of Holstein cows during the transit period of lactation and obtained from them heifers of the dairy period. The content of globulin in the blood serum of group 1 cows at 1 month of lactation is 56,0 g/l, at 3 months 53,9 g / l, which is significantly higher than the level in other groups (P≤0,05). In group 3 cows at the 3rd month of lactation, creatinine significantly increased to 74,8 mmol/l (P≤0,05). The blood content of alkaline phosphatase in 1 month of lactation in all examined animals is normal. The blood glucose level in cows is kept in the range of 3,6-4,0 at 1 month and 2,7 – 4,3 at 3 months of lactation (at the norm of 2,0 – 4,8 mmol/l). The concentration of total blood protein in calves at 3 months is within the normal range, but the variation was from 70,3 in group 1 to 84,4 g / l in group 3 (P≤0,05). Significant changes in the serum creatinine content at the 3rd month of life of experimental calves of group 3 up to 73,6 mmol/l (P≤0,10) within the normal range determine the intensity of adaptive mechanisms. Glucose in the blood serum of heifers is at the upper limit of the norm in groups 1 and 2 – 4,9 mmol/l (the norm is 4,8 mmol/l), which indicates a fairly high energy security of the calves ' diet. Total bilirubin in the blood serum of heifers of groups 1 and 2 is slightly higher than normal (the upper limit of the norm is 8,15) – 9,3 and 8,7 mmol/l. By the third month, the total bilirubin content in the blood of group 2 heifers increased to 10,7 mmol/l (P≤0,05), in the rest – within the normal range.

Physiological and Biochemical Parameters of Holstein Heifers when Adding to their Diet Bio-Drugs Containing Cuprum and Cobalt Nanoparticles

2017 ◽  
Vol 13 ◽  
pp. 123-129
Author(s):  
Petr M. Makarov ◽  
Irina A. Stepanova ◽  
Anna A. Nazarova ◽  
Svetlana D. Polishchuk ◽  
Gennadiy I. Churilov
Keyword(s):  
Weight Gain ◽  
Amino Acid ◽  
Amino Acid Composition ◽  
Growth And Development ◽  
Biochemical Parameters ◽  
Physiological State ◽  
Live Weight ◽  
Blood Parameters ◽  
Cobalt Nanoparticles ◽  
Physiological And Biochemical

The article presents the influence of biopreparations containing nanoparticles of cobalt and cuprum on the physiological state of Holstein heifers in a case of adding them to the diet. We have studied parameters of the animals’ growth and development in dynamics of live weight gain, clinical and biochemical blood parameters, the leucogram and amino acid composition of the experiment animals’ blood during the experiment.

Interactions between benthic molluscs in a Sulawesi mangal, Indonesia: the cerithiid mud-creeper Cerithium coralium and potamidid mud-whelks, Terebralia spp.

2003 ◽  
Vol 83 (3) ◽  
pp. 483-487 ◽  
Author(s):  
R.S.K. BARNES
Keyword(s):  
Feeding Rate ◽  
Inhibitory Effect ◽  
High Density ◽  
Sediment Surface ◽  
Normal Range ◽  
Numerous Species ◽  
Faecal Pellets ◽  
Strong Inhibitory Effect ◽  
Deposit Feeding ◽  
Very High

The sediment surface within the Osbornia belt of a mangal on Pulau Hoga, Tukang Besi Islands, Sulawesi, Indonesia, is dominated inter alia by deposit-feeding gastropod molluscs at a mean density of some 230 ind m−2 although, unusually, species of Cerithidea do not occur. Densities of the two most numerous species, the potamidid mud-whelk Terebralia sulcata and the Cerithidea-like cerithiid mud-creeper Cerithium coralium, are inversely correlated, although the species occurred together in 42% of quadrat samples. Within and beyond the normal range of field densities of each species (C. coralium mean 153 m−2; T. sulcata mean 75 m−2) there was no evidence of intraspecific depression of feeding rate, as assessed by the production of faecal pellets, although this was significantly reduced in the occasional very high density aggregations of C. coralium (>1100 m−2). The presence of the larger T. sulcata did appear to have a strong inhibitory effect on feeding in C. coralium; the converse, however, could not be demonstrated. Abundances of Terebralia palustris and C. coralium were also inversely correlated where the two co-occurred.

Drought stress: Effect on morphological, physiological and biochemical attributes and its management in wheat

2017 ◽  
Vol 17 (2) ◽  
pp. 181
Author(s):  
Vaishali ◽  
Aastha ◽  
Vishakha Burman ◽  
Khyati Lehari ◽  
Naresh Pratap Singh ◽  
...  
Keyword(s):  
Drought Stress ◽  
Stress Effect ◽  
Physiological And Biochemical

scholarly journals Neutrophil and Monocyte Kinetics in a Case of Cyclic Neutropenia

Blood ◽  
1974 ◽  
Vol 43 (4) ◽  
pp. 565-571 ◽  
Author(s):  
G. Meuret ◽  
T. M. Fliedner
Keyword(s):  
Turnover Rate ◽  
Cell Types ◽  
Neutrophilic Granulocytes ◽  
Normal Range ◽  
Total Blood ◽  
Cyclic Neutropenia ◽  
Disappearance Time ◽  
Remission Phase ◽  
Blood Granulocyte ◽  
Kinetics Of

Abstract The kinetics of neutrophilic granulocytes and monocytes were examined simultaneously in a patient suffering from cyclic neutropenia. During the remission phase of the disease the observed kinetic data for both cell types did not deviate significantly from the normal range. At a stage just before the minimal blood granulocyte count was reached, the total blood granulocyte pool was diminished and the granulocyte half disappearance time shortened to 2.3 hr. Moreover, the intravascular granulocyte distribution changed in favor of the marginal granulocyte pool. During the neutropenic phase, the intravascular monocyte pools were Increased and monocyte half-disappearance time was prolonged to 14 hr; the monocyte turnover rate was 2.4-fold higher than during remission.

Vitamin Imbalance in Metabolic Disease

1962 ◽  
Vol 8 (6) ◽  
pp. 561-569 ◽  
Author(s):  
Harry Sobotka
Keyword(s):  
Folic Acid ◽  
Side Effects ◽  
Vitamin B12 ◽  
Clinical Medicine ◽  
Physiological State ◽  
Serum Vitamin ◽  
Preventive Therapy ◽  
Wide Field ◽  
Normal Range ◽  
General Importance

Abstract Like other constituents of blood or serum, the deviation of a vitamin titer from the normal range may mean a number of things: reduced intake or absorption, increased utilization, increased demand, increased excretion will all cause a decrease of titer; their opposites, an increase. A vitamin is often the etiological center of a disease, as vitamin B12 and folic acid in macrocytic anemias. Here, because of the obvious implications for diagnosis and therapy, the determination of the "nucleogenic" vitamins, B12 and folic acid, is imperative in the routine of clinical hematology. Where the connection between a vitamin and a disease is less transparent a wide field remains open for the discovery of meaningful correlations between vitamin content of body fluids and tissues to physiologic or pathologic events. To single out the case of a physiological state of general importance, the vitamin equilibrium between mother and newborn offers now possibilities for the management of pregnancy, especially in regions where preventive "shot-in-the-dark" polyvitamin therapy is financially impossible. In the field of pathology, the significance of vitamin B12 in toxemia of pregnancy deserves further study. The so-called normal range of blood and serum vitamin levels is always derived from observations on healthy young subjects. Why not a comparison with healthy old subjects, whose percentage in the population is steadily increasing? Much may be learned about the cause of the decrease of physiological function and of the increased susceptibility to organic disease in old age, if the role of vitamins as parameter of these alterations were investigated with a view to preventive therapy. A glance at vitamins in clinical medicine opens a wide panorama with challenging aspects in hepatic conditions, in oxalosis and calculus disease, in obscure but widely spread neurological diseases, and in many others. Astute clinical observations, combined with knowledge of the function and mechanism of vitamin action, will bring vitamin analysis into the picture as a useful tool. Special mention must be accorded to iatrogenic effects, where the usefulness of novel synthetic drugs is impaired by untoward side effects of obscure etiology. Some of these side effects may find their explanation in the inhibitory action of the drug upon a vitamin, as in the case of Primidone vs. folic acid (15). The mode of the toxic action of Thalidomide has not yet been determined. Because of our previous experience with the use of protozoa in the detection of metabolic lesions induced by drugs, as exemplified already in the case of Primidone, Frank and Baker have studied the antimetabolic nature of thalidomide, using Ochromonas danica, Ochromonas malhamensis, and Euglena gracilis; they found inhibition of growth which was overcome by nicotinic acid or amide, by nicotinamide adenine dinucleotide (NAD, formerly DPN), or by vitamin K. This points to interference by thalidomide with the pathway of cellular oxidative phosphorylation. While thalidomide is remarkably nontoxic to the nonpregnant animal, the blocking of normal morphogenesis in the fetus must be ascribed to this metabolic interference. In general, such relationships appear to be fortuitous until the structural chemical kinship of drug and vitamin is recognized.

Notes on Methemoglobin Determination

1960 ◽  
Vol 6 (2) ◽  
pp. 148-152 ◽  
Author(s):  
Thomas Leahy ◽  
Roger Smith
Keyword(s):  
Normal Range ◽  
Instrument Error ◽  
Total Blood ◽  
Frequent Contact ◽  
Total Pigment ◽  
Significant Difference ◽  
Effective Instrument ◽  
Petroleum Fuels ◽  
Blood Pigment

Abstract The Evelyn-Malloy procedure for the determination of methemoglobin in blood has been modified for use with a Coleman Jr. spectrophotometer by using a lower dilution of blood to reduce the effective instrument error from a possible 10 per cent to a possible 3 per cent. The method has been further modified to give results directly as the per cent methemoglobin of the total blood pigment. The normal range for this determination appears to be up to 2 per cent of the total pigment present as methemoglobin. A statistically significant difference was observed between the means of the methemoglobin percentages of a normal group and a group of persons whose occupation placed them in frequent contact with petroleum fuels.

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