An Individual with a High Prevalence of aTat-Defective Provirus in Peripheral Blood

1993 ◽  
Vol 9 (12) ◽  
pp. 1265-1268 ◽  
Author(s):  
ESTER SABINO ◽  
CECILIA CHENG-MAYER ◽  
ALLEN MAYER
Keyword(s):  
Peripheral Blood ◽  
High Prevalence ◽  
Defective Provirus

High prevalence of HCMV and viral load in tumor tissues and peripheral blood of glioblastoma multiforme patients

2013 ◽  
Vol 86 (11) ◽  
pp. 1953-1961 ◽  
Author(s):  
Claudia Januário dos Santos ◽  
Lucas Matheus Stangherlin ◽  
Eberval Gadelha Figueiredo ◽  
Clemar Corrêa ◽  
Manoel Jacobsen Teixeira ◽  
...  
Keyword(s):  
Viral Load ◽  
Glioblastoma Multiforme ◽  
Peripheral Blood ◽  
Tumor Tissues ◽  
High Prevalence

Peripheral Blood HPC Counts Are Augmented in CML Patients with Cytogenetic Findings of Disease as Compared to Patients in Cytogenetic Remission.

Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 4691-4691
Author(s):  
Ernesto de Meis ◽  
Rita C.B. Morais ◽  
Luize O. Carvalho ◽  
Arthur Moellmann-Coelho ◽  
Maria M.K. Martinez ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Myeloid Leukemia ◽  
Leukocyte Count ◽  
Philadelphia Chromosome ◽  
Cell Disease ◽  
Differential Leukocyte Count ◽  
Non Invasive ◽  
Cd34 Cells ◽  
High Prevalence ◽  
Cytogenetic Remission

Abstract Chronic Myeloid Leukemia (CLM) is a stem cell disease characterized by inhibition of apoptosis and increased proliferation of bone marrow (BM) compounds. Evaluation of hematopoetic precursors cells on the peripheral blood (PB) of these patients show a high prevalence of leukemic CD34+ cells. Recently it was demonstrated that measurement of HPC by IMI channel on Sysmex showed an acceptable correlation between Hematopoetic Progenitors CD34+ cells counts. The aim of this work was to compare precursor cells (HPC) numbers in the PB of CML patients with disease and under remission. For this we studied 61 CML patients that had been treated with different protocols. From these 22 were in cytogenetic remission but 39 still presented more than 5% BM cells with Philadelphia chromosome (Ph+). Although the normal levels of CD34+ HPC in PB is considered to be very low, we considered less than 0.05% of leukocytes as normality. HPC in PB were counted using an automated peripheral blood counter (Sysmex XE-2100). We found that Ph+ CML patients had a significant increased number of PB HPC compared to CML patients under remission (with a confidence interval of 95%, and a corrected Yates analyses with X2 16.78 and p<0.0001). The increase in PB HPC was not related with the number of white cells counts at moment of the exam. These findings suggest that the presence of a high number of PB HPC in CML can be used as a non-invasive marker of the disease, more reliable than total and differential leukocyte count.

scholarly journals Prevalence of Eperythrozoon spp. infection and congenital eperythrozoonosis in humans in Inner Mongolia, China

2000 ◽  
Vol 125 (2) ◽  
pp. 421-426 ◽  
Author(s):  
DIANXIANG YANG ◽  
XIUZHENG TAI ◽  
YING QIU ◽  
SHENG YUN
Keyword(s):  
Electron Microscope ◽  
Pregnant Women ◽  
Developing Country ◽  
Seasonal Variations ◽  
Peripheral Blood ◽  
Inner Mongolia ◽  
Large Scale ◽  
Blood Samples ◽  
High Prevalence ◽  
Umbilical Cords

Eperythrozoon is an obligate parasitic bacteria found in many species of animals. A large scale investigation of the prevalence of Eperythrozoon spp. in humans, was conducted in a developing country using light, electron microscope and animal inoculation. Samples were collected in undeveloped areas of Inner Mongolia in China over a 2-year period of 1994–6. Of the 1529 investigated samples, 35·3% were found to be Eperythrozoon spp. positive. The prevalence of infection was associated with occupation and seasonal variations. The infections were mainly mild, in 89·6% of cases (excluding pregnant women and their children). Of 74 pregnant women tested in the areas of high prevalence, 44 were confirmed Eperythrozoon spp. positive. Similarly, eperythrozoa were found in all 44 umbilical cords tested and in the neonatal peripheral blood samples taken at birth. These data suggest that eperythrozoa can be transmitted via the placenta.

scholarly journals High rates of infection by blood parasites during the nestling phase in UK Columbids with notes on ecological associations

Parasitology ◽  
2016 ◽  
Vol 144 (5) ◽  
pp. 622-628 ◽  
Author(s):  
JENNY C. DUNN ◽  
JENNIFER E. STOCKDALE ◽  
EMMA L. BRADFORD ◽  
ALEXANDRA MCCUBBIN ◽  
ANTONY J. MORRIS ◽  
...  
Keyword(s):  
Infection Rate ◽  
Peripheral Blood ◽  
Parasite Infection ◽  
Blood Parasite ◽  
Blood Parasites ◽  
Dead End ◽  
High Prevalence ◽  
Apparent Infection Rate ◽  
Ecological Associations ◽  
The Uk

SUMMARYStudies of blood parasite infection in nestling birds rarely find a high prevalence of infection. This is likely due to a combination of short nestling periods (limiting the age at which nestlings can be sampled) and long parasite prepatent periods before gametocytes can be detected in peripheral blood. Here we examine rates of blood parasite infection in nestlings from three Columbid species in the UK. We use this system to address two key hypotheses in the epidemiology of avian haemoparasites: first, that nestlings in open nests have a higher prevalence of infection; and second, that nestlings sampled at 14 days old have a higher apparent infection rate than those sampled at 7 days old. Open-nesting individuals had a 54% infection rate compared with 25% for box-nesters, probably due to an increased exposure of open-nesting species to dipteran vectors. Nestlings sampled at 14 days had a 68% infection rate compared with 32% in nestlings sampled at 7 days, suggesting that rates of infection in the nest are high. Further work should examine nestlings post-fledging to identify rates of successful parasite infection (as opposed to abortive development within a dead-end host) as well as impacts on host post-fledging survival and behaviour.

Donor CMV serostatus has no impact on CMV viremia or disease when prophylactic granulocyte transfusions are given following allogeneic peripheral blood stem cell transplantation

Blood ◽  
2003 ◽  
Vol 101 (5) ◽  
pp. 2067-2069 ◽  
Author(s):  
Ravi Vij ◽  
John F. DiPersio ◽  
Partha Venkatraman ◽  
Kathryn Trinkaus ◽  
Lawrence T. Goodnough ◽  
...  
Keyword(s):  
Stem Cell ◽  
Peripheral Blood ◽  
Peripheral Blood Stem Cell ◽  
Blood Stem Cell ◽  
Preemptive Therapy ◽  
Granulocyte Colony Stimulating Factor ◽  
Donor Pool ◽  
High Prevalence ◽  
The Impact ◽  
Stimulating Factor

We studied the impact of donor cytomegalovirus (CMV) serologic status on CMV viremia and disease when prophylactic granulocyte colony-stimulating factor (G-CSF)–mobilized granulocyte transfusions (GTs) were given following allogeneic peripheral blood stem cell (AlloPBSC) transplantation. A cohort of 83 patients who received 2 prophylactic GTs from ABO-compatible stem cell donors following AlloPBSC transplantation was compared with a cohort of 142 patients who did not. AlloPBSC donors were eligible for granulocyte donation irrespective of their CMV serostatus. Recipients received no prophylactic therapy for CMV. Donor CMV serostatus had no impact on CMV viremia and disease in the 2 cohorts. Our data show that in an era of effective surveillance and preemptive therapy for CMV, AlloPBSC recipients can safely receive 2 transfusions of prophylactic G-CSF–mobilized granulocyte components from CMV-seropositive AlloPBSC donors. This knowledge may help expand the donor pool in areas with a high prevalence of CMV in the general population.

The Growth of Herpesvirus mulatto in Human Fibroblast

1974 ◽  
Vol 32 ◽  
pp. 244-245
Author(s):  
Glennelle Washington ◽  
Philip P. McGrath ◽  
Peter R. Graze ◽  
Ivor Royston
Keyword(s):  
Rhesus Monkey ◽  
Microscopic Study ◽  
Electron Microscopic Study ◽  
Peripheral Blood ◽  
Human Fibroblast ◽  
Rhesus Monkeys ◽  
Human Fibroblasts ◽  
Electron Microscopic ◽  
Specific Antisera ◽  
Peripheral Blood Leucocytes

Herpes-like viruses were isolated from rhesus monkey peripheral blood leucocytes when co-cultivated with WI-38 cells. The virus was originally designated rhesus leucocyte-associated herpesvirus (LAHV) and subsequently called Herpesvirus mulatta (HVM). The original isolations were from juvenile rhesus monkeys shown to be free of antibody to rhesus cytomegalic virus. The virus could only be propagated in human or simian fibroblasts. Use of specific antisera developed from HVM showed no relationship between this virus and other herpesviruses. An electron microscopic study was undertaken to determine the morphology of Herpesvirus mulatta (HVM) in infected human fibroblasts.

Sign in / Sign up

Export Citation Format

Share Document