scholarly journals Trends in the nontuberculous mycobacterial disease mortality rate in Japan: A nationwide observational study, 1997-2016

2020 ◽  
Author(s):  
Ko Harada ◽  
Hideharu Hagiya ◽  
Tomoko Funahashi ◽  
Toshihiro Koyama ◽  
Mitsunobu R Kano ◽  
...  
Keyword(s):  
Mortality Rate ◽  
The Elderly ◽  
Mortality Rates ◽  
Vital Statistics ◽  
Female Population ◽  
Health Authorities ◽  
Disease Mortality ◽  
Crude Mortality ◽  
Public Health Authorities ◽  
Nationwide Observational Study

Abstract Background The incidence of nontuberculous mycobacterial (NTM) infections has been increasing worldwide, becoming a significant healthcare burden especially among elderly people. This study aimed to evaluate the trends in NTM-associated mortality in Japan. Methods This study used vital statistics data and data on all NTM-associated deaths (N=18,814) among individuals aged ≥40 years in Japan from 1997 to 2016. We calculated the crude and age-adjusted mortality rates by age and sex and used joinpoint regression to analyze trends and estimate the average annual percentage change (AAPC). We compared crude NTM- and tuberculosis (TB)-associated mortality rates by sex. Results The overall crude annual mortality rate increased from 0.63/100,000/year in 1997 to 1.93/100,000/year in 2016 and was the highest among individuals aged 80–84 years. The AAPC of the crude mortality rates among males of all ages and females aged 40–59 years were stable but increased among females aged 60–79 years (3.5%, 95% confidence interval [CI]: 2.8–4.3%) and ≥80 years (4.3%, 95% CI: 3.7–4.9%). Among males, the age-adjusted mortality rates did not show a significant trend, while among females, the rates increased over the study period (AAPC: 4.6%, 95% CI: 2.7–6.6%). In females, the crude NTM-associated mortality rate exceeded the TB mortality rate in 2014, 2015, and 2016. Conclusions  NTM mortality increased in Japan between 1997 and 2016, especially among the elderly female population. Given the increasing NTM-associated mortality and susceptible aging population, public health authorities in Japan should pay greater attention to NTM infections.

scholarly journals On Dynamics of Gender-Specific Mortality Among the Population of the Republic of Belarus in the Second Half of the XX – the Beginning of the XXI Centuries

2017 ◽  
Vol 24 (3) ◽  
Author(s):  
A Romanova ◽  
O Krasko
Keyword(s):  
Mortality Rate ◽  
Environmental Changes ◽  
Research Work ◽  
Mortality Rates ◽  
Female Mortality ◽  
Female Population ◽  
Male And Female ◽  
Crude Mortality ◽  
The Republic ◽  
Population Mortality

Aim of the study: to evaluate the dynamics and to make a comparative analysis of male and female mortality among the population of Belarus Republic during 1959 – 2015.Materials and methods. The data on natural population movement in the Republic of Belarus during 1959 – 2015 have been analyzed in the research work. Crude and standardized mortality rates have been calculated using the direct standardization according to the world standard (Standard “World”), approved by WHO. JoinPoint software was used to investigate time trends as well as office suite MSEXCEL 2010.Results of the study. The minimum values of male and female crude and standardized mortality rates were established in 1964. Throughout the study period, the male population mortality rate grew 1.8-fold (based on crude rates – 2.4-fold), the female population mortality rate – 1.6-fold (based on crude rates – 2.2-fold). During 1985 – 2005, the differences in crude mortality rates among men and women grew 1.2-fold, and during 1962 – 2011, the differences in standardized rates increased 1.8-fold. Since 2003, the mortality rate among men and since 1999, the death rate among women has declined with an annual decrease rate to be more than twice as high as compared to an annual mortality increase registered during its growth.Conclusion. Since the 1960s, the changes in population age structure of the male and female population affected the crude mortality rates. The male and female mortality growth is due to an increased unfavorable impact of combined environmental factors. The adaptive capacity of women to sustain environmental changes contributed to their later entry into the period of mortality growth, as compared to men. The mortality rate reduction in men since 2003 and the excess of a decrease over an increase rate is associated with a set of state measures aimed at protecting and strengthening the public health in the republic.

scholarly journals The Need for Early Management in Patients With COVID-19

2021 ◽  
Author(s):  
Audrey Giraud-Gatineau ◽  
Sébastien Cortaredona ◽  
Jean-Christophe Lagier ◽  
Matthieu Million ◽  
Philippe Brouqui ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Mortality Rates ◽  
Lower Mortality ◽  
Treatment Center ◽  
Early Management ◽  
Clinical Criteria ◽  
Health Authorities ◽  
Public Health Authorities ◽  
Set Up ◽  
The Impact

Abstract In March 2020, the IHU Méditerranée Infection set up a screening and treatment center for patients with COVID-19, a system that has been ultimately recommended by French public health authorities. The recent publication of the profiles of patients hospitalized in France published by the Directorate for Research, Studies, Evaluation and Statistics gives us the opportunity to measure the impact of this multidisciplinary early management system coupled with screening on mortality at 90 days. Analysis of the data shows that the system established at IHU-MI was associated with lower mortality, taking age and sex into account. Regarding the age-standardized mortality rate, mortality rates were lower than national data regardless of the period of the epidemic. Early management seems to have significantly decreased the mortality rate in the under-60 age group, suggesting the importance of early management, regardless of age. In addition, these patients had pejorative clinical criteria (high NEWS-2 score, ICU visits, oxygen saturation below 95%) requiring hospitalization, and co-morbidities that are now known to be aggravating factors [7]. This reinforces the need to care for all individuals, regardless of age. Early medical care, as part of a system integrating a screening center and a day hospital, may explain the lower mortality rates.

Mortality Rates

PEDIATRICS ◽  
1989 ◽  
Vol 84 (2) ◽  
pp. 402-403
Author(s):  
S. GORHAM BABSON
Keyword(s):  
United States ◽  
Mortality Rate ◽  
Infant Mortality ◽  
The United States ◽  
Mortality Rates ◽  
Vital Statistics ◽  
Infant Mortality Rate ◽  
December Issue ◽  
Health Authorities ◽  
To Receive

We are fortunate to receive Myron Wegman's annual summary of vital statistics in the December issue of Pediatrics. This valuable information is not readily available to the pediatrician. I am somewhat discomforted by the emphasis continually made by health authorities and lay press on the United States' unfavorable international position in its infant mortality rate of 10.4 per 1000 live-born infants—now 19th in relation to other advanced countries for 1986. However, eight of these countries have less than 100 000 births each year, and most of them have relative ethnic homogeneity.

Endovascular Aortic Repair in Patients of Advanced Age

2021 ◽  
pp. 152660282110493
Author(s):  
Mitri K. Khoury ◽  
Micah A. Thornton ◽  
Christopher A. Heid ◽  
Jacqueline Babb ◽  
Bala Ramanan ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Survival Benefit ◽  
Elective Surgery ◽  
Endovascular Aneurysm Repair ◽  
The Elderly ◽  
Mortality Rates ◽  
Current Data ◽  
Aortic Aneurysms ◽  
Advanced Age ◽  
The Impact

Purpose: Treatment decisions for the elderly with abdominal aortic aneurysms (AAAs) are challenging. With advancing age, the risk of endovascular aneurysm repair (EVAR) increases while life expectancy decreases, which may nullify the benefit of EVAR. The purpose of this study was to quantify the impact of EVAR on 1-year mortality in patients of advanced age. Materials and Methods: The 2003–2020 Vascular Quality Initiative Database was utilized to identify patients who underwent EVAR for AAAs. Patients were included if they were 80 years of age or older. Exclusions included non-elective surgery or missing aortic diameter data. Predicted 1-year mortality of untreated AAAs was calculated based on a validated comorbidity score that predicts 1-year mortality (Gagne Index, excluding the component associated with AAAs) plus the 1-year aneurysm-related mortality without repair. The primary outcome for the study was 1-year mortality. Results: A total of 11 829 patients met study criteria. The median age was 84 years [81, 86] with 9014 (76.2%) being male. Maximal AAA diameters were apportioned as follows: 39.6% were <5.5 cm, 28.6% were 5.5–5.9 cm, 21.3% were 6.0–6.9 cm, and 10.6% were ≥7.0 cm. The predicted 1-year mortality rate without EVAR was 11.9%, which was significantly higher than the actual 1-year mortality rate with EVAR (8.2%; p<0.001). The overall rate of perioperative MACE was 4.4% (n = 516). Patients with an aneurysm diameter <5.5cm had worse actual 1-year mortality rates with EVAR compared to predicted 1-year mortality rates without EVAR. In contrast, those with larger aneurysms (≥5.5cm) had better actual 1-year mortality rates with EVAR. The benefit from EVAR for those with Gagne Indices 2–5 was largely restricted to those with AAAs ≥ 7.0cm; whereas those with Gagne Indices 0–1 experience a survival benefit for AAAs larger than 5.5 cm. Conclusion: The current data suggest that EVAR decreases 1-year mortality rates for patients of advanced age compared to non-operative management in the elderly. However, the survival benefit is largely limited to those with Gagne Indices 0–1 with AAAs ≥ 5.5 cm and Gagne Indices 2–5 with AAAs ≥ 7.0 cm. Those of advanced age may benefit from EVAR, but realizing this benefit requires careful patient selection.

scholarly journals A Spatial Analysis of Tuberculosis Related Mortality in South Africa

2021 ◽  
Vol 18 (22) ◽  
pp. 11865
Author(s):  
Dan Kibuuka ◽  
Charles Mpofu ◽  
Penny Neave ◽  
Samuel Manda
Keyword(s):  
Public Health ◽  
South Africa ◽  
Mortality Rate ◽  
Spatial Epidemiology ◽  
Hot Spot ◽  
Mortality Rates ◽  
Cold Spot ◽  
The South ◽  
Female Population ◽  
Death Rates

Background: South Africa, with an estimated annual tuberculosis (TB) incidence of 360,000 cases in 2019, remains one of the countries with the largest burden of TB in the world. The identification of highly burdened TB areas could support public health policy planners to optimally target resources and TB control and prevention interventions. Objective: To investigate the spatial epidemiology and distribution of TB mortality in South Africa in 2010 and its association with area-level poverty and HIV burden. Methods: The study analysed a total of 776,176 TB deaths for the period 2005–2015. Local and global and spatial clustering of TB death rates were investigated by Global and Local Moran’s Indices methods (Moran’s I). The spatial regression analysis was employed to assess the effect of poverty and HIV on TB mortality rates. Results: There was a significant decrease in TB mortality rate, from 179 per 100,000 population in 2005 to 60 per 100,000 population in 2015. The annual TB mortality rate was higher among males (161.5 per 100,000 male population; (95% confidence interval (CI) 132.9, 190.0) than among females (123.2 per 100,000 female population; (95% CI 95.6, 150.8)). The 35–44 age group experienced higher TB mortality rates, regardless of gender and time. Hot spot clusters of TB mortality were found in the South-Eastern parts of the country, whereas cold spot clusters were largely in the north-eastern parts. Tuberculosis death rates were positively associated with poverty, as measured by the South African Multidimension Poverty Index (SAMPI) as well TB death rates in the neighbouring districts. Conclusion: The findings of this study revealed a statistically significant decrease in TB deaths and a disproportionate distribution of TB deaths among certain areas and population groups in South Africa. The existence of the identified inequalities in the burden of TB deaths calls for targeted public health interventions, policies, and resources to be directed towards the most vulnerable populations in South Africa.

scholarly journals Using Satellite Images and Deep Learning to Identify Associations Between County-Level Mortality and Residential Neighborhood Features Proximal to Schools: A Cross-Sectional Study

2021 ◽  
Vol 9 ◽  
Author(s):  
Joshua J. Levy ◽  
Rebecca M. Lebeaux ◽  
Anne G. Hoen ◽  
Brock C. Christensen ◽  
Louis J. Vaickus ◽  
...  
Keyword(s):  
United States ◽  
Deep Learning ◽  
Mortality Rate ◽  
Satellite Images ◽  
The United States ◽  
Mortality Rates ◽  
Image Features ◽  
County Level ◽  
Crude Mortality Rate ◽  
Crude Mortality

What is the relationship between mortality and satellite images as elucidated through the use of Convolutional Neural Networks?Background: Following a century of increase, life expectancy in the United States has stagnated and begun to decline in recent decades. Using satellite images and street view images, prior work has demonstrated associations of the built environment with income, education, access to care, and health factors such as obesity. However, assessment of learned image feature relationships with variation in crude mortality rate across the United States has been lacking.Objective: We sought to investigate if county-level mortality rates in the U.S. could be predicted from satellite images.Methods: Satellite images of neighborhoods surrounding schools were extracted with the Google Static Maps application programming interface for 430 counties representing ~68.9% of the US population. A convolutional neural network was trained using crude mortality rates for each county in 2015 to predict mortality. Learned image features were interpreted using Shapley Additive Feature Explanations, clustered, and compared to mortality and its associated covariate predictors.Results: Predicted mortality from satellite images in a held-out test set of counties was strongly correlated to the true crude mortality rate (Pearson r = 0.72). Direct prediction of mortality using a deep learning model across a cross-section of 430 U.S. counties identified key features in the environment (e.g., sidewalks, driveways, and hiking trails) associated with lower mortality. Learned image features were clustered, and we identified 10 clusters that were associated with education, income, geographical region, race, and age.Conclusions: The application of deep learning techniques to remotely-sensed features of the built environment can serve as a useful predictor of mortality in the United States. Although we identified features that were largely associated with demographic information, future modeling approaches that directly identify image features associated with health-related outcomes have the potential to inform targeted public health interventions.

scholarly journals Mortality from endometrial cancer in female population of Belgrade

2004 ◽  
Vol 61 (3) ◽  
pp. 267-272
Author(s):  
Vesna Pantovic ◽  
Mirjana Jarebinski ◽  
Tatjana Pekmezovic ◽  
Anita Knezevic ◽  
Darija Kisic
Keyword(s):  
Endometrial Cancer ◽  
Mortality Rate ◽  
Malignant Tumors ◽  
Age Groups ◽  
Mortality Rates ◽  
Mortality Decline ◽  
Female Population ◽  
Average Percentage ◽  
Standardized Mortality Rate

Data about mortality from malignant tumors of endometrium were analyzed in the Belgrade area during the period 1975-2000. The obtained results showed that the average percentage of endometrial cancer in mortality structure from all the cancers of female population was 2.65%. During the observed 26-years period, malignant tumors of endometrium constituted 17.38% of all the tumors of gynecological localization. The standardized mortality rate in 1975 (population worldwide used as a standard) 7.06/100 000 population while in 2000 it was 1.78/100 000 population, respectively, which showed almost fourfold mortality decline during the observed period (y=4.72-0.16x). A trend of declining risk of dying from endometrial cancer was present in all the age groups. The obtained results indicated that in the observed period the average mortality rates ranged from 0.14/100 000 population in females aged up to 34 years (y=0.30-0.01x), and reached the highest value in females aged 65-74 years (14.57/100 000; y=23.43-0.66x), and 75 years of age and over (19.62/100 000; y=31.17-0.85x).

scholarly journals Characteristics of mortality in the Orenburg region population in 2011-2017

2020 ◽  
Vol 5 (2) ◽  
pp. 99-104
Author(s):  
Evgenii L. Borschuk ◽  
Dmitrii N. Begun ◽  
Tatyana V. Begun
Keyword(s):  
Mortality Rate ◽  
Causes Of Death ◽  
Age Groups ◽  
Circulatory System ◽  
Mortality Rates ◽  
Female Population ◽  
Orenburg Region ◽  
The Third ◽  
Circulatory System Diseases ◽  
External Causes

Objectives - to study the mortality indicators, their dynamics and structure, in the population of the Orenburg region in the period of 2011-2017. Material and methods. The study was conducted using the data from the territorial authority of statistics in the Orenburg region in the period from 2011 to 2017. The analytical, demographic and statistical methods were implemented for the study of the demographic indicators. Results. Cities and municipal settlements of the Orenburg region with high mortality indicators were included in the second and fourth clusters during the cluster analysis. The first and third clusters included cities and municipal settlements with an average mortality. The most favorable position has the Orenburg area with the lowest mortality rate in the region in 2017 - 8.4%. The dynamics of mortality rates among the male and female population tends to decrease, more pronounced dynamics is in men. Though, the male population is characterized by higher mortality rates in all age groups. The leading position among the causes of death is taken by diseases of the circulatory system (46.3% of the total mortality). The second position is occupied by tumors (17.2%), the third - by external causes (8.4%). Mortality from circulatory system diseases and from external causes has reduced. The dynamics of mortality from tumors does not change significantly. The rank of leading causes of death is not identical in the clusters: in the third and fourth clusters, the other causes occupy the second place in the structure of mortality, while tumors occupy the third. Conclusion. In the Orenburg region, the mortality rate is higher than overage in the Russian Federation by 0.9 per 1000 people. The study revealed significant territorial differences in the mortality rates. In general, the mortality among men in all age groups is higher than the mortality of women. The mortality rate from diseases of the circulatory system plays the leading role in the structure of mortality, but has the tendency for decline. Until 2006, the mortality from external causes ranked the second place, now the second place is taken by death from tumors The mortality from external causes is decreasing; mortality from tumors does not change significantly. The obtained results could be used by local authorities in developing the program of public health protection and assessing its effectiveness.

Annual Summary of Vital Statistics—1991

PEDIATRICS ◽  
1992 ◽  
Vol 90 (6) ◽  
pp. 835-845
Author(s):  
Myron E. Wegman
Keyword(s):  
Mortality Rate ◽  
Infant Mortality ◽  
Divorce Rate ◽  
The United States ◽  
Mortality Rates ◽  
Vital Statistics ◽  
Natural Increase ◽  
Infant Mortality Rate ◽  
Marriage Rates ◽  
Final Data

Between 1990 and 1991, provisional data show that the infant mortality rate decreased again, from 9.1 to 8.9, a decline of 2% in contrast to the 7% decline from 1989 to 1990. Birth, death, and marriage rates were also lower, but the divorce rate stayed at about the same level as in 1990. Natural increase in the population, excess of births over deaths, was less than 2 million, 4% less than the increase in 1990. Detailed analysis of changes and of the influence of factors like age and race requires final data; at the time of preparation of this report final birth and death data were available only through 1989. For a variety of reasons, including staff shortages and delays in receipt of state data by the National Center for Health Statistics (NCHS), final data for 1990, which would usually have been available in late August 1992, are not expected before early 1993. Unlike recent years, the decline in the infant mortality rate was only in the neonatal component, which decreased 3.6%. Postneonatal mortality increased, for the first time in many years, by 1.6%, suggesting that the decline in the total is related more to therapeutic advances in neonatology than to improved prevention. Internationally, newly independent Latvia was added to the list of countries with rates less than 15, but Costa Rica was deleted. With the reunification of Germany the list shrank to 28 and, by default, the United States moved up from 21st to 20th. Some 12.5 million births, less than 9% of the world total, took place in countries with under-5 mortality rates of less than 20 per 1000. At the other end of the scale, 42% of the world's births occurred in countries with under-5 mortality rates of more than 140 per 1000. The median under-5 mortality rate for those countries in 1990 was 189 per 1000, meaning that almost 20% of the infants born alive in these countries died before their fifth birthday.

scholarly journals Ecologic association between influenza and COVID-19 mortality rates in European countries

2020 ◽  
Vol 148 ◽  
Author(s):  
S. Petti ◽  
B. J. Cowling
Keyword(s):  
Public Health ◽  
Cardiovascular Disease ◽  
Confidence Interval ◽  
The Elderly ◽  
Mortality Rates ◽  
Population Based ◽  
Control Measures ◽  
Mortality Trends ◽  
Cardiovascular Disease Mortality ◽  
Disease Mortality

Abstract Ecologic studies investigating COVID-19 mortality determinants, used to make predictions and design public health control measures, generally focused on population-based variable counterparts of individual-based risk factors. Influenza is not causally associated with COVID-19, but shares population-based determinants, such as similar incidence/mortality trends, transmission patterns, efficacy of non-pharmaceutical interventions, comorbidities and underdiagnosis. We investigated the ecologic association between influenza mortality rates and COVID-19 mortality rates in the European context. We considered the 3-year average influenza (2014–2016) and COVID-19 (31 May 2020) crude mortality rates in 34 countries using EUROSTAT and ECDC databases and performed correlation and regression analyses. The two variables – log transformed, showed significant Spearman's correlation ρ = 0.439 (P = 0.01), and regression coefficients, b = 0.743 (95% confidence interval, 0.272–1.214; R2 = 0.244; P = 0.003), b = 0.472 (95% confidence interval, 0.067–0.878; R2 = 0.549; P = 0.02), unadjusted and adjusted for confounders (population size and cardiovascular disease mortality), respectively. Common significant determinants of both COVID-19 and influenza mortality rates were life expectancy, influenza vaccination in the elderly (direct associations), number of hospital beds per population unit and crude cardiovascular disease mortality rate (inverse associations). This analysis suggests that influenza mortality rates were independently associated with COVID-19 mortality rates in Europe, with implications for public health preparedness, and implies preliminary undetected SARS-CoV-2 spread in Europe.

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