scholarly journals Ecophysiology of egg rejection in hosts of avian brood parasites: new insights and perspectives

2021 ◽  
Author(s):  
Francisco Ruiz-Raya
Keyword(s):  
Potential Role ◽  
Physiological State ◽  
Host Responses ◽  
Future Research ◽  
Egg Rejection ◽  
Fitness Costs ◽  
Brood Parasites ◽  
Proximate Mechanisms ◽  
Proximate Factors

Abstract Egg rejection is the most effective and widespread defence used by host species to counteract the extreme fitness costs frequently imposed by obligate avian brood parasites. Yet, the proximate mechanisms underlying between- and within-individual variation in host responses remain poorly explored. Emerging evidence suggests that egg rejection is dependent on individual physiological state, and draws attention to the role of hormones as mediators of flexible antiparasitic responses. In this perspective article, I outline recent advances in our understanding of the proximate factors that mediate egg rejection. I also point out some areas where knowledge remains still lacking, especially those related to the development and maintenance of effective cognitive functions, the potential role of oxidative stress, immunological state and developmental stressors. I propose new hypotheses that stimulate future research on behavioural host responses towards brood parasitism.

Potential Role of Cytokines in Children with Acute Appendicitis and Acute Mesenteric Lymphadenitis

2011 ◽  
Vol 11 (1) ◽  
pp. 130-133
Author(s):  
Astra Zviedre ◽  
Arnis Engelis ◽  
Mohit Kakar ◽  
Aigars Pētersons
Keyword(s):  
Early Detection ◽  
Acute Appendicitis ◽  
Inflammatory Mediators ◽  
Potential Role ◽  
Clinical Symptoms ◽  
Future Research ◽  
Mesenteric Lymphadenitis ◽  
Proper Diagnosis ◽  
Near Future

Potential Role of Cytokines in Children with Acute Appendicitis and Acute Mesenteric Lymphadenitis Although, AAP and AML have different etiological factors, clinical symptoms are very much similar but treatment tactics in both the disease differ a lot. In case of AML, treatment is more conservative and does not require hospitalization while in case of AAP immediate hospitalization and maybe further surgery can be mandatory. With the identification of group of cytokines serum inflammatory mediators IL-8, IL-10, IL-12[p70], IL-17, TNF-a and MCP-1, it is believed early and proper diagnosis of AAP in the near future. Research of cytokines-serum inflammatory mediators has opened new opportunities for an early detection and differentiation of these two diseases in children.

The relationship between cooperative and competitive behavioral tendencies and trust in coworkers

2020 ◽  
Vol 8 (3) ◽  
pp. 345-360
Author(s):  
Ece Ömüriş ◽  
Ferda Erdem ◽  
Janset Özen Aytemur
Keyword(s):  
Mixed Methods Research ◽  
Potential Role ◽  
Employee Relations ◽  
Hierarchical Regression ◽  
Future Research ◽  
Content Type ◽  
Tourism Sector ◽  
Behavioral Tendencies ◽  
The Relationship

PurposeThis study aims to investigate the relationship between cooperative and competitive behavioral tendencies and trust of coworkers in organizations. Two main hypotheses were developed. The first hypothesis was that cooperativeness and trust in coworkers is positively correlated. The second hypothesis was that competitiveness and trust in coworkers is negatively correlated.Design/methodology/approachThe sample was 442 Turkish tourism sector employees in a labor-intensive industry. Two scales were used to measure trust in coworkers and cooperativeness/competitiveness. A hierarchical regression analysis was performed to understand how individuals' behavioral tendency affects their coworkers' trust in them.FindingsThe findings strongly supported the first hypothesis, in that cooperativeness was positively correlated with trust in coworkers. The second hypothesis was only partially supported because there was no significant relationship between competitiveness and the competency and trustworthiness dimensions of trust. Unselfishness aspect of trust, however, was negatively correlated with competitiveness.Research limitations/implicationsThe main contribution of this study is to show that employee cooperativeness and competitiveness can affect trust in coworker relations. However, the measurement of competitiveness and cooperativeness measurement had limitations due to differences in the culture-specific meanings of cooperation and competition. Future research employing mixed methods research is needed to further explain the content of the two tendencies and the relationship between the concepts.Originality/valueThe literature on trust and employee relations tends to focus more on the issue of trust between managers and subordinates while neglecting the complex and multifaceted structure of trust in employee–employer relations. However, new working forms mean that horizontal relations are increasingly important. Therefore, more research is needed to address the tendencies and structures that affect trust in coworkers. This study draws attention to the potential role of cooperative and competitive behaviors in trust in horizontal employee relations.

scholarly journals Developmental Aspects of SARS-CoV-2, Potential Role of Exosomes and Their Impact on the Human Transcriptome

2021 ◽  
Vol 9 (4) ◽  
pp. 54
Author(s):  
Navneet Dogra ◽  
Carmen Ledesma-Feliciano ◽  
Rwik Sen
Keyword(s):  
Immune Response ◽  
Potential Role ◽  
Developmental Stages ◽  
In Utero ◽  
Host Tissue ◽  
Future Research ◽  
Rna Transcripts ◽  
Immune Related Genes ◽  
Pregnant Mothers

With over 4.8 million deaths within 2 years, time is of the essence in combating COVID-19. The infection now shows devastating impacts on the younger population, who were not previously predicted to be vulnerable, such as in the older population. COVID-19-related complications have been reported in neonates whose mothers were infected with SARS-CoV-2 during pregnancy, and in children who get infected. Hence, a deeper understanding of the pathophysiology of COVID-19 during various developmental stages and placental transmission is essential. Although a connection has not yet been established between exosomal trafficking and the placental transmission of COVID-19, reports indicate that SARS-CoV-2 components may be trafficked between cells through exosomes. As the infection spreads, the transcriptome of cells is drastically perturbed, e.g., through the severe upregulation of several immune-related genes. Consequently, a major outcome of COVID-19 is an elevated immune response and the detection of viral RNA transcripts in host tissue. In this direction, this review focuses on SARS-CoV-2 virology, its in utero transmission from infected pregnant mothers to fetuses, SARS-CoV-2 and exosomal cellular trafficking, transcriptomic impacts, and RNA-mediated therapeutics against COVID-19. Future research will establish stronger connections between the above processes to develop diagnostic and therapeutic solutions towards COVID-19 and similar viral outbreaks.

scholarly journals Potential role of septins in oral carcinogenesis: An update and avenues for future research

2012 ◽  
Vol 16 (1) ◽  
pp. 73 ◽  
Author(s):  
Rooban Thavarajah ◽  
KM Vidya ◽  
Elizabeth Joshua ◽  
UmadeviK Rao ◽  
K Ranganathan
Keyword(s):  
Potential Role ◽  
Future Research ◽  
Oral Carcinogenesis

scholarly journals Potential Role of Phenolic Extracts of Mentha in Managing Oxidative Stress and Alzheimer’s Disease

Antioxidants ◽  
2020 ◽  
Vol 9 (7) ◽  
pp. 631
Author(s):  
Doaa M. Hanafy ◽  
Geoffrey E. Burrows ◽  
Paul D. Prenzler ◽  
Rodney A. Hill
Keyword(s):  
Oxidative Stress ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Potential Role ◽  
The Elderly ◽  
Future Research ◽  
Phenolic Constituents ◽  
The Central Nervous System ◽  
Developed Nations

With an increase in the longevity and thus the proportion of the elderly, especially in developed nations, there is a rise in pathological conditions that accompany ageing, such as neurodegenerative disorders. Alzheimer’s disease (AD) is a neurodegenerative disease characterized by progressive cognitive and memory decline. The pathophysiology of the disease is poorly understood, with several factors contributing to its development, such as oxidative stress, neuroinflammation, cholinergic neuronal apoptotic death, and the accumulation of abnormal proteins in the brain. Current medications are only palliative and cannot stop or reverse the progression of the disease. Recent clinical trials of synthetic compounds for the treatment of AD have failed because of their adverse effects or lack of efficacy. Thus, there is impetus behind the search for drugs from natural origins, in addition to the discovery of novel, conventional therapeutics. Mints have been used traditionally for conditions relevant to the central nervous system. Recent studies showed that mint extracts and/or their phenolic constituents have a neuroprotective potential and can target multiple events of AD. In this review, we provide evidence of the potential role of mint extracts and their derivatives as possible sources of treatments in managing AD. Some of the molecular pathways implicated in the development of AD are reviewed, with focus on apoptosis and some redox pathways, pointing to mechanisms that may be modulated for the treatment of AD, and the need for future research invoking knowledge of these pathways is highlighted.

From cooperation to competition: an interaction-based contingency theory of communities of practice

2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Brian C. Britt
Keyword(s):  
Communities Of Practice ◽  
Potential Role ◽  
Contingency Theory ◽  
Theoretical Framework ◽  
Future Research ◽  
Community Members ◽  
Content Type ◽  
Internal Competition ◽  
Practical Implications

Purpose The purpose of this paper is to provide a theoretical framework that explains the roles and viability of both cooperation and competition as they emerge in communities of practice. Although the usefulness of cooperation in communities of practice is well-understood, few studies have considered the role of internal competition, and those that have generally only explored cases in which antagonistic behavior led to the community’s collapse. Design/methodology/approach A contingency theory of communities of practice is developed based on the manifestations of members’ participation. Findings This theory demonstrates the root causes of fracturing and also provides a foundation for studying communities of practice that have previously defied explanation. Research limitations/implications This manuscript explains the potential role and limitations of internal competition in communities of practice, as well as the emergence of subgroups based on differing preferences for cooperation and/or competition. Future research should examine the manifestation and ramifications of such individual differences between community members. Practical implications Practitioners can use this theoretical framework to assess communities of practice that they oversee, diagnose potential pitfalls and take corrective action to mitigate potentially toxic influences or inject additional motivating forces that would sustain the community. Originality/value This theoretical framework diverges from previous assumptions that internal competition is necessarily toxic for communities of practice, showing the value that it may offer in some contexts.

Seeking Forgiveness: Theoretical Context and an Initial Empirical Study

2000 ◽  
Vol 28 (1) ◽  
pp. 21-35 ◽  
Author(s):  
Steven J. Sandage ◽  
Everett L. Worthington ◽  
Terry L. Hight ◽  
Jack W. Berry
Keyword(s):  
Clinical Practice ◽  
Potential Role ◽  
Initial Study ◽  
Future Research ◽  
Developmental Level ◽  
Theoretical Base ◽  
Self Monitoring ◽  
The Past ◽  
Developmental Factors

While research on granting forgiveness has exploded recently, no theoretical or empirical attention has been directed at seeking forgiveness. We lay a theoretical base for the study of seeking forgiveness and report our initial study bearing on the concept. We investigate the potential role of some personality and developmental factors that might promote seeking forgiveness. Students ( N = 232) who indicated having transgressed against a partner in the past year completed questionnaires on religiosity, age, developmental level of reasoning about forgiveness, narcissism, self-monitoring, and the level to which they had sought forgiveness. Neither religiosity nor age significantly predicted seeking forgiveness. Developmental level of reasoning about forgiveness predicted seeking forgiveness beyond religiosity and age. Narcissism and self-monitoring significantly predicted seeking forgiveness. We outline limitations of the study and implications for future research, clinical practice, and integration.

A potential role of cyclin-dependent kinase inhibitor 1 (p21/WAF1) in the pathogenesis of endometriosis: Directions for future research

2019 ◽  
Vol 133 ◽  
pp. 109414
Author(s):  
Nikolaos Zarkadoulas ◽  
Vasilios Pergialiotis ◽  
Dimitrios Dimitroulis ◽  
Konstantinos Stefanidis ◽  
Christos Verikokos ◽  
...  
Keyword(s):  
Potential Role ◽  
Kinase Inhibitor ◽  
Future Research ◽  
Cyclin Dependent Kinase ◽  
Cyclin Dependent Kinase Inhibitor ◽  
P21 Waf1

Justice at Work, Job Stress, and Employee Health

2007 ◽  
Vol 36 (3) ◽  
pp. 487-504 ◽  
Author(s):  
Kaori Fujishiro ◽  
Catherine A. Heaney
Keyword(s):  
Organizational Justice ◽  
Occupational Stress ◽  
Job Stress ◽  
Potential Role ◽  
Employee Health ◽  
Health Interventions ◽  
Future Research ◽  
Occupational Epidemiology ◽  
Work Site

A small but growing literature has documented an association between justice at work and employee health. However, the pathways and mechanisms underlying this association are not well understood. This article proposes a conceptual framework that bridges the organizational justice, occupational stress, and occupational epidemiology literatures. Justice appraisals are proposed to be both important mediators and moderators in the causal flow from exposure to the organizational environment to employee health. The potential role of justice in enhancing employee health is compared to that of the well-established concepts of social support and job control. Directions for future research are suggested, along with strategies for overcoming challenges inherent in this multidisciplinary area of research. Implications for work-site health interventions are discussed.

scholarly journals Formation and Function of Liquid-Like Viral Factories in Negative-Sense Single-Stranded RNA Virus Infections

Viruses ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 126
Author(s):  
Justin M. Su ◽  
Maxwell Z. Wilson ◽  
Charles E. Samuel ◽  
Dzwokai Ma
Keyword(s):  
Rna Viruses ◽  
Rna Virus ◽  
Host Responses ◽  
Future Research ◽  
Virus Infections ◽  
Infected Cells ◽  
And Function ◽  
Negative Sense ◽  
Liquid Liquid Phase Separation

Liquid–liquid phase separation (LLPS) represents a major physiochemical principle to organize intracellular membrane-less structures. Studies with non-segmented negative-sense (NNS) RNA viruses have uncovered a key role of LLPS in the formation of viral inclusion bodies (IBs), sites of viral protein concentration in the cytoplasm of infected cells. These studies further reveal the structural and functional complexity of viral IB factories and provide a foundation for their future research. Herein, we review the literature leading to the discovery of LLPS-driven formation of IBs in NNS RNA virus-infected cells and the identification of viral scaffold components involved, and then outline important questions and challenges for IB assembly and disassembly. We discuss the functional implications of LLPS in the life cycle of NNS RNA viruses and host responses to infection. Finally, we speculate on the potential mechanisms underlying IB maturation, a phenomenon relevant to many human diseases.

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