Effects of feeding diets containing low crude protein and coarse wheat bran as alternatives to zinc oxide in nursery pig diets

Author(s):  
Kelsey L Batson ◽  
Hilda I Calderón ◽  
Mike D Tokach ◽  
Jason C Woodworth ◽  
Robert D Goodband ◽  
...  

Abstract Two experiments determined the effects of crude protein (CP) in diets containing coarse wheat bran (CWB) with or without pharmacological levels of Zn on weanling pig growth performance. In Exp. 1, treatments included a positive control (21% CP) with 3,000 mg/kg Zn in phase 1 and 2,000 mg/kg in phase 2; negative control (21% CP) with 110 mg/kg Zn, and four diets containing 4% CWB and 110 mg/kg Zn formulated to 21, 19.5, 18, or 16.5% CP. The three diets with 21% CP and CWB contained 1.40% standardized ileal digestible (SID) Lys in phase 1 and 1.35% SID Lys in phase 2, while the 19.5, 18, and 16.5% CP diets contained 1.35, 1.25 and 1.20% Lys, respectively. Pigs fed the diet containing pharmacological Zn had increased (P < 0.05) ADG and G:F compared to the negative control and the 21% CP CWB diet. Reducing CP decreased ADG and G:F (linear, P = 0.002). In Exp. 2, diets consisted of: 1) positive control with 2,000 mg/kg of Zn and 21% CP (1.35% SID Lys); 2) 110 mg/kg Zn and 21% CP; and 3 diets with 110 mg/kg Zn and 18% CP with 3) 1.2% SID Lys; 4) 1.35% SID Lys by the addition of crystalline AA, and 5) diet 4 with added non-essential AA. Pigs fed 21% CP with Zn had increased (P = 0.001) ADG compared to those fed 18% CP (1.35% SID Lys) or 1.2% SID Lys. In summary, added Zn improved growth performance, but reducing CP did not.

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 92-93
Author(s):  
Fernanda Laskoski ◽  
Wade M Hutchens ◽  
Mike D Tokach ◽  
Jason C Woodworth ◽  
Robert D Goodband ◽  
...  

Abstract A total of 300 pigs (DNA 241 × 600; initially 4.2 kg) were used to evaluate the effects of different nutritional strategies to replace zinc oxide (ZnO) in nursery diets. Treatments consisted of A) Positive control (21% CP; ZnO providing 3,000 ppm Zn from d 0 to 7, and 2,000 ppm Zn from d 7 to 25); B) Negative control (NC; no ZnO); C) NC plus 1.2% Na diformate; D) NC with 4% coarse ground wheat bran; E) NC with low crude protein (18%) by adding high levels of feed grade amino acids; and F) the combination of NC with 18% crude protein (CP), 1.2% Na diformate, and 4% coarse ground wheat bran. There were 5 pigs per pen and 10 pens per treatment in a completely randomized design. Data were analyzed with the Proc Mixed procedure in SAS. For the overall period (d 0 to 46), pigs fed diets containing ZnO had greater (P < 0.001) ADG, ADFI, and final BW than other treatments, with pigs fed the NC with 18% CP having the lowest performance. Pigs fed the NC diet without any nutritional alternative had the lowest fecal dry matter (DM; P < 0.050) and highest fecal scores (P < 0.050). Pigs fed diets with ZnO had similar fecal DM and scores as pigs fed the diet containing the combination of 1.2% Na diformate, 4% coarse ground wheat bran, and low (18%) CP, but greater (P < 0.023) fecal DM than pigs fed the alternatives used individually. This study suggests none of the strategies used alone were effective at replacing ZnO while the use of low CP and amino acids reduced performance further. Combining the three alternatives tested as a replacement to ZnO improved fecal DM content and fecal score but did not result in improved growth performance.


Author(s):  
Fernanda Laskoski ◽  
Mike D Tokach ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
Steve S Dritz ◽  
...  

Abstract A total of 300 weanling pigs (Line 400 × 200, DNA, Columbus, NE, initially 4.83 kg) were used in a 46-d trial to evaluate the effects of different nutritional strategies to replace pharmacological levels of Zn, provided by zinc oxide (ZnO), in nursery diets on growth performance and fecal dry matter (DM). Six treatments with 10 replicate pens per treatment and 5 pigs per pen were used. Diets consisted of: 1) Positive control (ZnO providing 3,000 mg/kg added Zn from d 0 to 7 and 2,000 mg/kg added Zn from d 8 to 25 and 21% crude protein, CP); 2) Negative control (NC; no added ZnO); 3) NC plus 1.2% Na Diformate; 4) NC with 4% coarse ground wheat bran; 5) NC but formulated to 18% CP); and 6) The combination of NC with 18% CP, 1.2% Na Diformate, and 4% coarse ground wheat bran. The diets formulated to 18% CP contained 1.2% standardized ileal digestible (SID) Lys from day 0 to 25 whereas the 21% CP diets contained 1.4% SID Lys from day 0 to 7 and 1.35% SID Lys from d 7 to 25. From d 25 to 46, all pigs were fed a common diet. From d 0 to 7, no differences in any variables were observed between treatments. From d 7 to 25, pigs fed the diet with added ZnO had greater (P < 0.01) ADG and ADFI than all other treatments. Pigs fed the diet formulated to 18% CP had decreased (P < 0.01) ADG compared with pigs fed the other diets. From d 25 to 46, no previous treatment effects on ADG or G:F were observed. Overall (day 0 to 46), pigs fed the diet with added ZnO from d 0 to 25 had greater (P < 0.01) ADG, ADFI, and final BW than pigs fed added Na Diformate, or 4% coarse ground wheat bran, or with the 18% CP diet, with pigs fed the combination of the additives intermediate. There was no evidence for differences in overall G:F. Pigs fed the NC diet had the lowest fecal DM and highest fecal scores (P < 0.05) indicating the greatest incidence of loose stools. Pigs fed added ZnO had greater fecal DM than pigs fed the NC, 4% added wheat bran, or 18% CP diets, with pigs fed the combination of additives intermediate (P < 0.01). These results suggest that adding pharmacological levels of Zn from ZnO improves nursery pig performance and increases DM content of feces when compared with pigs fed diets with either, Na Diformate, 4% course wheat bran, or 18% CP alone. However, a combination of all 3 alternatives appeared to be additive and partially restore growth performance similar to adding pharmacological levels of Zn.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 204-205
Author(s):  
Kelsey L Batson ◽  
Hilda I Calderon Cartagena ◽  
Mike D Tokach ◽  
Jason C Woodworth ◽  
Robert D Goodband ◽  
...  

Abstract A total of 355 pigs (DNA 200x400; initially 5.6 kg) were used to evaluate the effects of coarse wheat bran and crude protein (CP) level in diets without pharmacological levels of zinc oxide on nursery pig performance and fecal dry matter (DM%). Pigs were allotted to 1 of 6 treatments in a completely randomized design with 5 pigs per pen and 12 pens per treatment. Treatment diets were fed in two phases (d 0 to 7 and 7 to 21) followed by a common diet fed d 21 to 45. Treatments included a positive control diet with ZnO, negative control without ZnO, and negative control with 4% wheat bran and formulated to contain 21, 19.5, 18, or 16.5% CP. All diets contained 1.35% SID lysine except the 18 and 16.5% (1.25 and 1.20% lysine) CP diets. Data were analyzed using the lmer function from the lme4 package in R. During the experimental period, decreasing CP decreased (linear, P< 0.05) ADG, G:F, and d 21 BW, but increased (linear, P=0.005) fecal DM%. Pigs fed the diet containing ZnO had increased (P< 0.050) ADG, ADFI, and G:F compared to the negative control and diet with 21% CP and wheat bran. From d 21 to 45, pigs previously fed the 21% CP diet with wheat bran had increased (P< 0.05) ADG compared to the positive control. Fecal DM on d 45 and G:F increased (P< 0.05) for pigs fed the 21% CP, wheat bran diet and negative control compared to those fed the positive control. Overall, pigs fed low CP diets had decreased (P< 0.05) ADG while pigs fed the positive control had greater (P< 0.05) ADG compared to the negative control. Additional research is needed to determine if modifying low CP, wheat bran diets will elicit benefits of increased fecal DM% while maintaining growth performance.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 190-191
Author(s):  
Thomas E Weber ◽  
Julie Salyer ◽  
Audrey Walter ◽  
Yan Lei ◽  
Yulin Ma ◽  
...  

Abstract Two studies were conducted to evaluate the effects of a feed sweetener on nursery pig performance. In the first study, 360 pigs (PIC 800 x 1050; 6.22 ± 1.20 kg) were blocked by BW and pen location and assigned to 3 treatment groups: 1) Control; 2) 100 mg/kg feed sweetener; or 3) 200 mg/kg feed sweetener. There were 12 pens containing 10 pigs for each treatment. In the second study, 540 pigs (6.12 ± 0.39 kg) were blocked by BW and pen location and assigned to 3 treatment groups: 1) negative control; 2) 100 mg/kg feed sweetener; or 3) 0.5% carob bean. There were 18 pens containing 10 pigs per pen for each treatment. A 3-phase feeding program was used, and diets were fed for 6 wk in both studies. In study 1, ADFI, ADG, and gain:feed were increased (P < 0.05) during Phase 1 for pigs fed diets with 100 mg/kg or 200 mg/kg sweetener. Phase 2 ADFI and ADG were increased (P < 0.05) in pigs fed 100 mg/kg sweetener when compared to the control. Increased BW (P < 0.05) were observed on D 7, 14 and 21 for animals fed 100 mg/kg or 200 mg/kg sweetener. The mortality rate was decreased (P < 0.05) in the group of animals fed 100 mg/kg sweetener compared to the control. In study 2, there was no effect of sweetener or carob bean on growth performance, feed intake or gain:feed. However, mortality rate was decreased (P < 0.05) in pigs fed the sweetener compared to pigs fed carob bean. In conclusion, the feed sweetener improved early nursery performance in one study and had no effect in another study. Mortality was decreased by supplementation with 100 mg/kg sweetener when compared to a negative control in one study and compared pigs fed carob bean in the second study. Further research is needed to explore differences observed between studies to optimize feed sweetener usage strategy.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 94-95
Author(s):  
Kelsey Hammers ◽  
Hilda I Calderon ◽  
Mike D Tokach ◽  
Jason C Woodworth ◽  
Robert D Goodband ◽  
...  

Abstract A total of 360 pigs (DNA 200′400, initially 5.0 kg) were used in a 45-d growth trial to determine the effects of fiber source and crude protein (CP) level in diets without pharmacological levels of ZnO on nursery pig growth performance and fecal dry matter (DM). Pigs were randomly assigned to 1 of 8 treatments with 5 pigs/pen and 9 pens/treatment. Treatments were arranged in a 2×4 factorial with main effects of CP (21 or 18%) and fiber source [none, coarse wheat bran (CWB), oat hulls, or cellulose (Arbocel, J. Rettenmaier USA, Schoolcraft, MI)]. Fiber source was added to equalize the level of insoluble fiber contributed from 4% CWB, resulting in the addition of 1.85% oat hulls or 1.55% cellulose. Diets were fed in two phases (d 0 to 10 and 10 to 24) followed by a common diet (d 24 to 45). The 21% CP diets contained 1.40% SID Lys in phase 1 and 1.35% SID Lys in phase 2. Treatment diets were formulated to a maximum SID Lys:digestible CP level of 6.35%, thus SID Lys decreased in the 18% CP (1.25% SID Lys) diets. Data were analyzed using the lmer function in R. No fiber source × CP level interactions (P >0.05) were observed. Decreasing dietary CP decreased (P = 0.05) ADG, G:F, and d 24 BW. Overall, ADG and d 45 BW decreased (P < 0.05) for pigs fed 18% CP diets. No main effects of fiber source were observed for growth performance throughout the study. Fecal DM increased (P < 0.05) for pigs fed added cellulose compared to pigs fed no fiber or CWB in the experimental period. In conclusion, reducing dietary CP decreased growth performance and the inclusion of cellulose improved fecal DM of nursery pigs.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 22-23
Author(s):  
Richard A Mudarra ◽  
Tsung Cheng Cheng Tsai ◽  
Kristopher Bottoms ◽  
Thomas S Shieh ◽  
Casey Bradly ◽  
...  

Abstract To evaluate the effect of bioactive peptide (P) in combination with high level of zinc (HZ) or acidifiers on growth performance, complete blood cell counts (CBC) and nutrient digestibility in nursery pigs, a total of 288 weaned pigs (PIC1050xDNA600) were stratified by initial BW within gender and allotted to 1of 7 treatments. Treatments for phase 1&2 were: 1) nutrient adequate positive control with HZ (PC), 2) nutrient deficient negative control with HZ (NC, -0.13% SID Lysine by reducing fish meal), 3) NC+0.25% peptide (0.25PZ), 4) NC+0.5% peptide (0.5PZ), 5) NC+0.25% peptide with standard zinc (0.25P), 6) NC+0.5% peptide with standard zinc (0.5P), 7) as 5 + 0.1% sodium butyrate and 0.5% benzoic acid (PSB). All pigs were fed a common low Zn diet (197 ppm) during phase 3. The whole blood was obtained from a close-to-average pen-BW pig repeatedly at weaning, and at the end of phase 2 and 3 to determine CBC. Titanium dioxide was used as an indigestible marker to determine nutrient digestibility. Data were analyzed using the Mixed procedures of SAS as a RCBD with treatment as fixed effect, and BW block as random effect. In overall phase 1&2, pigs fed PSB had similar ADG and BW when compared to pigs fed 0.25PZ and both were greater than NC pigs (Table 1). With the same inclusion rate of peptide, pigs fed a high zinc diet had greater BW and ADG than pigs fed a standard zinc diet. PSB pigs had the greatest G:F ratio and nitrogen digestibility among treatments. Increasing peptide in high zinc diets gradually decreased Neutrophil-to-lymphocyte ratio. This study indicates that the improvement in growth performance from pigs fed peptide is pharmaceutical zinc dependent and acidifiers can be an alternative to replace ZnO without affecting growth performance.


2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 209-210
Author(s):  
Ehsan Khafipour ◽  
Anirikh Chakrabarti ◽  
Maria Sardi ◽  
Briana Kozlowicz ◽  
Derek B Petry ◽  
...  

Abstract This study investigated the effects of a postbiotic from Lactobacillus acidophilus fermentation (LAF) on pig gut microbiome during nursery. Piglets (n = 32) at weaning (day 21 ± 2) were randomized based on BW (7.4 ± 1.7 kg) and received basal diets that met NRC nutrient requirements for phase 1 (d 0–14) and phase 2 (d 14–32) post-wean. Treatments included i) NC, negative control; ii) PC, antibiotic positive control, iii) LAFa (Dia-V™ Nursery, Diamond V, IA) supplemented at 1000 ppm in phase 1 and 1500 ppm in phase 2, and iv) LAFb (Dia-V™ Nursery) supplemented at 2000 and 1000 ppm during phase 1 and 2, respectively. Fecal samples were collected on d 0, 7, 14, and 32 post-wean and subjected to DNA extraction and long read Nanopore shotgun metagenomics to assess composition, function and progression of gut microbiome and their correlations with BW. On d7, PC and LAF supplemented pigs numerically were closer to microbiome of d 14 and 32 compared to NC pigs. From d 0 to 32, pigs progressed through five compositional clusters (P < 0.05). By d 32, more pigs from PC and LAF groups were exhibiting a compositional cluster that was characterized by dominance of members of Bacteroidetes phylum including several Prevotella species. From d 0 to d 32, four microbiome functional clusters were observed (P < 0.05) with varying abundances of carbohydrate-active-enzymes (CAZy). Pigs in LAF groups compared to other treatments exhibited clusters with greater abundances of CAZy that was correlated with greater BW on d 32 (P = 0.004). The 2000 ppm supplementation of LAF in phase 1 and 1500 ppm in phase 2 numerically increased all measured of diversity compared to 1000 ppm. Overall, while PC and LAF groups promoted more similar microbiome compositional clusters compared to NC, LAF pigs exhibited superior functional clusters.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 197-198
Author(s):  
Jacob A Richert ◽  
Jorge Y P Palencia ◽  
Clayton S Chastain ◽  
Morgan T Thayer ◽  
Brian T Richert ◽  
...  

Abstract The objective of this study was to determine the optimal level of Cordyceps mushroom powder inclusion in diets for nursery pigs. One-hundred sixty crossbred pigs [(Duroc × (York × Landrace)] weaned at 18.8 d of age and weighing an average of 5.94 kg were used in a 35 day, 4 phase growth trial to evaluate Cordyceps mushroom powder as potential alternative to carbadox in nursery pig diets. Pigs were allotted by weight, sex, litter, and assigned to body weight (BW) blocks. Within BW blocks, sex ratios were constant in each pen. Each pen within a BW block was randomly assigned a dietary treatment. Growth performance was analyzed as a RCB design using BW, ADG, ADFI, G:F using GLM procedure of SAS 9.4. There were 5 or 6 pigs/pen and 6 pens/treatment. Five diets were used in the study: a negative diet or a positive control (Carbadox, 55 ppm); 300 or 600 ppm mushroom powder, and a step down treatment (900, 900, 450, 300, 150 ppm mushroom powder during weeks 1 through 5, respectively). At various points of the study, pigs fed the 300 ppm and the step-down mushroom powder treatments tended to have improved (P < 0.10) growth performance compared with those fed the negative control diet. During Phase 4 of the study, pigs fed Carbadox had greater ADG (P < 0.02) and improved feed efficiency (P < 0.09) compared to pigs fed the negative control diet. However, overall data showed that there were no statistical differences among treatments (P > 0.05). In summary, pigs fed 300 ppm mushroom powder or the step-down treatment showed comparable growth performance to pigs fed Carbadox. However, future research is needed under a greater disease challenge to examine mushroom powder’s full potential as an alternative to antibiotics.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 194-195
Author(s):  
Carine M Vier ◽  
Mariana Boscato Menegat ◽  
Kiah M Gourley ◽  
Steve S Dritz ◽  
Mike D Tokach ◽  
...  

Abstract This study evaluated storing 3 commercial phytases for 90 d in an environmental chamber set at 29.4°C and 75% humidity on phytase stability and nursery pig growth performance and bone mineralization. The phytases [HiPhos GT (20,000 FYT/g, DSM Nutritional Products, Parsippany, NJ); Axtra Phy TPT (20,000 FTU/g, Dupont, Wilmington, DE), and Quantum Blue G (40,000 FTU/g, AB Vista, Plantation, FL)] were kept as pure forms or blended in a vitamin-trace mineral (VTM) premix and sampled on d 0, 30, 60, and 90 of storage. Regardless of source and form, analyzed phytase activity decreased (linear, P < 0.001) as storage increased. Afterwards, 300 nursery pigs (11.7 kg BW) were assigned to 1 of 8 treatments in a RCBD with 4-5 pigs/pen and 8 pens/treatment. Treatments included a negative (NC, 0.12% aP) and positive control (PC, 0.27% aP) without phytase; or NC with added phytase to provide 0.15% aP (1,000, 651 and 500 FTU/kg for HiPhos, Axtra Phy, and Quantum Blue, respectively). Negative control with added phytase treatments were manufactured with each phytase source previously stored in pure form or VTM premix for 90d. Pigs fed PC had greater (P < 0.001) ADG compared to pigs fed Axtra Phy stored in VTM or NC. Feed intake was similar for PC, phytases stored in pure forms, and HiPhos and Quantum Blue stored in VTM, and greater (P < 0.001) than pigs fed NC. Pigs fed PC or HiPhos stored in pure form had improved (P < 0.001) G:F compared to pigs fed NC. Bone mineralization was greater (P < 0.001) for pigs fed PC compared to NC, phytases stored in VTM, and Axtra Phy and Quantum Blue stored in pure form. Regardless of source and form, phytase activity decreased as storage increased. In this study, bone ash was reduced when phytases were stored for 90d in a VTM compared to the PC.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 69-70
Author(s):  
Kevin S Jerez Bogota ◽  
Christian Sanchez ◽  
Jimena Ibagon ◽  
Maamer Jlali ◽  
Pierre Cozannet ◽  
...  

Abstract Objective was to determine the effects of supplementing corn-soybean meal-based diets with a multi-enzyme on growth performance and apparent total tract digestibility (ATTD) of nutrients in growing pigs. A total of 276 pigs (BW = 33.99 ± 4.3 kg) were housed by sex in 45 pens of 6 or 7 pigs and fed 5 diets (9 pens/diet) in a randomized complete block design. Diets were positive control (PC); and negative control 1 (NC1) or negative control 2 (NC2) without or with multi-enzyme. The multi-enzyme used supplied at least 1,250, 860, 4,600, and 1,000 units of xylanase, β-glucanase, arabinofuranosidase and phytase per kilogram of diet, respectively. The PC was adequate in all nutrients according to NRC (2012) recommendations and had greater digestible P content than NC1 diet or NC2 diet by 0.134 percentage points. The NC1 diet had lower NE and digestible AA content than PC diet by 3%. The NC2 diet had lower NE and digestible AA content than PC diet by 5%. The diets were fed in 4 phases based on BW; Phase 1: 34–50 kg, Phase 2: 50–75 kg, Phase 3: 75–100 kg, and Phase 4: 100–120 kg. Nutrient digestibility was determined at the end of Phase 1. Overall (34–120 kg BW), pigs fed the PC and NC1 diets did not differ in ADG and ADFI. Pigs fed NC2 diet had lower (PPPP > 0.10). Supplemental multi-enzyme increased (P = 0.047) the ATTD of GE for NC2 diet. In conclusion, the NE and digestible AA and P can be lowered by ≤ 5% in multi-enzyme-supplemented diets without effects on growth performance pigs.


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