258 Comparing Post-hospitalization Global Health Scale Assessments in Male and Female Adult Burn Patients for Quality of Life

2018 ◽  
Vol 39 (suppl_1) ◽  
pp. S96-S96
Author(s):  
N Alver ◽  
K Koetsier ◽  
G Carrougher ◽  
L Muffley ◽  
N Gibran
Keyword(s):  
Quality Of Life ◽  
Global Health ◽  
Burn Patients ◽  
Female Adult ◽  
Male And Female

Advantages of a mini right axillary thoracotomy for congenital heart defect repair in children

2021 ◽  
pp. 1-6
Author(s):  
Jannika Dodge-Khatami ◽  
Ali Dodge-Khatami
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Global Health ◽  
Congenital Heart ◽  
Surgical Repair ◽  
Median Sternotomy ◽  
Axillary Approach ◽  
Post Operative Pain ◽  
The Right

Abstract Objectives: The mini right axillary thoracotomy is an alternative surgical approach to repair certain congenital heart defects. Quality-of-life metrics and clinical outcomes in children undergoing either the right axillary approach or median sternotomy were compared. Methods: Patients undergoing either approach for the same defects between 2018 and 2020 were included. Demographic details, operative data, and outcomes were compared between both groups. An abbreviated quality of life questionnaire based on the Infant/Toddler/Child Health Questionnaires focused on the patient’s global health, physical activity, and pain/discomfort was administered to all parents/guardians within two post-operative years. Results: Eighty-seven infants and children underwent surgical repair (right axillary thoracotomy, n = 54; sternotomy, n = 33) during the study period. There were no mortalities in either group. The right axillary thoracotomy group experienced significantly decreased red blood cell transfusion, intubation, intensive care, and hospital durations, and earlier chest tube removal. Up to 1 month, parents’ perception of their child’s degree and frequency of post-operative pain was significantly less after the right axillary thoracotomy approach. No difference was found in the patient’s global health or physical activity limitations beyond a month between the two groups. Conclusions: With the mini right axillary approach, surrogates of faster clinical recovery and hospital discharge were noted, with a significantly less perceived degree and frequency of post-operative pain initially, but without the quality of life differences at last follow-up. While providing obvious cosmetic advantages, the minimally invasive right axillary thoracotomy approach for the surgical repair of certain congenital heart lesions is a safe alternative to median sternotomy.

CLINICAL AND COST-EFFECTIVENESS OF DONEPEZIL, RIVASTIGMINE, AND GALANTAMINE FOR ALZHEIMER'S DISEASE

2002 ◽  
Vol 18 (3) ◽  
pp. 497-507 ◽  
Author(s):  
Andrew Clegg ◽  
Jackie Bryant ◽  
Tricia Nicholson ◽  
Linda McIntyre ◽  
Sofie De Broe ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cost Effectiveness ◽  
Global Health ◽  
Cochrane Library ◽  
The Impact ◽  
Health Cognition ◽  
Economic Studies

Objectives: Systematic review of the clinical and cost-effectiveness of donepezil, rivastigmine, and galantamine for people suffering from Alzheimer's disease.Methods: Sixteen electronic databases (including MEDLINE, the Cochrane Library, and Embase) and bibliographies of related papers were searched for published/unpublished English language studies, and experts and pharmaceutical companies were consulted for additional information. Randomized controlled trials (RCTs) and economic studies were selected. Clinical effectiveness was assessed on measurement scales assessing progression of Alzheimer's disease on the person's global health, cognition, functional ability, behavior and mood, and quality of life. Cost-effectiveness was presented as incremental cost per year spent in a nonsevere state (by Mini Mental Health State Examination) or quality-adjusted life-year.Results: Twelve of 15 RCTs included were judged to be of good quality. Although donepezil had beneficial effects in Alzheimer's patients on global health and cognition, rivastigmine on global health, and galantamine on global health, cognition, and functional scales, these improvements were small and may not be clinically significant. Measures of quality of life and behavior and mood were rarely assessed. Adverse effects were usually mild and transient. Cost-effectiveness base case estimates ranged from £2,415 savings to £49,476 additional cost (1997 prices) per unit of effect for donepezil and a small savings for rivastigmine. Estimates were not considered robust or generalizable.Conclusions: Donepezil, rivastigmine, and galantamine appear to have some clinical effect for people with Alzheimer's disease, although the extent to which these translate into real differences in everyday life remains unclear. Due to the nature of current economic studies, cost-effectiveness remains uncertain and the impact on different care sectors has been inadequately investigated. Further research is needed to establish the actual benefits of acetylcholinesterase inhibitors (AChEls) for people with Alzheimer's disease and their caregivers, the relationship of these changes to clinical management, and careful prospective evaluation of resource and budgetary consequences.

scholarly journals Dietary fruits and arthritis

2018 ◽  
Vol 9 (1) ◽  
pp. 70-77 ◽  
Author(s):  
Arpita Basu ◽  
Jace Schell ◽  
R. Hal Scofield
Keyword(s):  
Quality Of Life ◽  
Global Health ◽  
Significant Proportion ◽  
Health Concern

Arthritis is a global health concern affecting a significant proportion of the population and associated with reduced quality of life.

FOENIX-CCA2 quality of life data for futibatinib-treated intrahepatic cholangiocarcinoma (iCCA) patients with FGFR2 fusions/rearrangements.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 4097-4097
Author(s):  
Juan W. Valle ◽  
Antoine Hollebecque ◽  
Junji Furuse ◽  
Lipika Goyal ◽  
Funda Meric-Bernstam ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Global Health ◽  
Global Health Status ◽  
Phase 2 ◽  
Life Data ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Eq Vas

4097 Background: In FOENIX-CCA2 (NCT02052778), a pivotal phase 2 study among iCCA patients (pts) with FGFR2 fusions/rearrangements, the highly selective, irreversible FGFR1–4 inhibitor futibatinib demonstrated a confirmed objective response rate of 41.7%, with a 9.7-month median duration of response. Adverse events were manageable with dosing modifications that did not adversely impact on response. We report outcomes for the preplanned analysis of Patient-Reported Outcomes (PROs) during futibatinib treatment as a secondary objective of FOENIX-CCA2. Methods: Pts enrolled in FOENIX-CCA2 had locally advanced/metastatic unresectable iCCA with FGFR2 fusions/rearrangements, ≥1 prior line of therapy (including gemcitabine/cisplatin) and ECOG PS 0-1. Pts received oral futibatinib 20 mg continuous QD dosing per 21-day cycle. PRO measures included EORTC-QLQ-C30 (1 global health, 5 functional, 9 symptom scales), EQ-5D-3L, and EQ visual analogue scale (VAS). PROs were collected at screening, cycles 2 and 4, every 3 cycles thereafter, and end of treatment. PRO data were evaluated up to cycle 13, the last visit before data were missing for >50% of the PRO population (PRO primary assessment time point). Results: 92/103 (89.3%) pts enrolled had PRO completion data at baseline and a minimum of 1 follow-up assessment (median age 58 y, 56.5% female), with 48 pts having PRO data at cycle 13. At baseline, mean (SD) EORTC QLQ-C30 global health status score was 70.1 (19.4) and EQ VAS score 71.7 (20.3). Mean EORTC QLQ-C30 global health status scores were maintained from baseline to cycle 13, corresponding to 9.0 months on treatment, with no clinically meaningful (≥10-point) changes in individual functional measures (Table). EORTC QLQ-C30 scores across individual symptom measures were also stable from baseline through cycle 13; only constipation showed an average of 10.0-point worsening at only cycle 4. Mean EQ VAS scores were sustained from baseline to cycle 13 (mean change ranging -1.8 to +4.8 across cycles), with values maintained within the population norm range from across 20 countries. Conclusions: Quality of life data from the phase 2 FOENIX-CCA2 trial show that physical, cognitive and emotional functioning, and overall health status were maintained among pts with advanced iCCA receiving futibatinib. Clinical trial information: NCT02052778. [Table: see text]

scholarly journals Epidemiology of injuries, treatment (costs) and outcome in burn patients admitted to a hospital with or without dedicated burn centre (Burn-Pro): protocol for a multicentre prospective observational study

BMJ Open ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. e023709 ◽  
Author(s):  
Esther MM Van Lieshout ◽  
Daan T Van Yperen ◽  
Margriet E Van Baar ◽  
Suzanne Polinder ◽  
Doeke Boersma ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Burn Injury ◽  
Treatment Costs ◽  
Burn Patients ◽  
Severe Burns ◽  
Referral Criteria ◽  
Age Limit

IntroductionThe Emergency Management of Severe Burns (EMSB) referral criteria have been implemented for optimal triaging of burn patients. Admission to a burn centre is indicated for patients with severe burns or with specific characteristics like older age or comorbidities. Patients not meeting these criteria can also be treated in a hospital without burn centre. Limited information is available about the organisation of care and referral of these patients. The aims of this study are to determine the burn injury characteristics, treatment (costs), quality of life and scar quality of burn patients admitted to a hospital without dedicated burn centre. These data will subsequently be compared with data from patients with<10% total bodysurface area (TBSA) burned who are admitted (or secondarily referred) to a burn centre. If admissions were in agreement with the EMSB, referral criteria will also be determined.Methods and analysisIn this multicentre, prospective, observational study (cohort study), the following two groups of patients will be followed: 1) all patients (no age limit) admitted with burn-related injuries to a hospital without a dedicated burn centre in the Southwest Netherlands or Brabant Trauma Region and 2) all patients (no age limit) with<10% TBSA burned who are primarily admitted (or secondarily referred) to the burn centre of Maasstad Hospital. Data on the burn injury characteristics (primary outcome), EMSB compliance, treatment, treatment costs and outcome will be collected from the patients’ medical files. At 3 weeks and at 3, 6 and 12 months after trauma, patients will be asked to complete the quality of life questionnaire (EuroQoL-5D), and the patient-reported part of the Patient and Observer Scar Assessment Scale (POSAS). At those time visits, the coordinating investigator or research assistant will complete the observer-reported part of the POSAS.Ethics and disseminationThis study has been exempted by the medical research ethics committee Erasmus MC (Rotterdam, The Netherlands). Each participant will provide written consent to participate and remain encoded during the study. The results of the study are planned to be published in an international, peer-reviewed journal.Trial registration numberNTR6565.

scholarly journals Impact of plantar fasciitis on the quality of life of male and female patients according to the Foot Health Status Questionnaire

2018 ◽  
Vol Volume 11 ◽  
pp. 875-880 ◽  
Author(s):  
Patricia Palomo López ◽  
Ricardo Becerro de Bengoa Vallejo ◽  
Marta Elena Losa-Iglesias ◽  
David Rodríguez-Sanz ◽  
Cesar Calvo Lobo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Plantar Fasciitis ◽  
Foot Health ◽  
Male And Female ◽  
Health Status Questionnaire ◽  
Female Patients ◽  
Foot Health Status Questionnaire

scholarly journals Personal Strivings as Markers of Adolescents’ Quality of Life: a Gender Based Study

2017 ◽  
Vol 4 (3) ◽  
Author(s):  
Dr. Shilpi Aggarwal ◽  
Prof. Punam Midha
Keyword(s):  
Quality Of Life ◽  
Gender Stereotypes ◽  
Male And Female ◽  
Gender Comparison ◽  
Community Belonging ◽  
Gender Based ◽  
And Gender ◽  
Personal Strivings ◽  
Purposive Sample

Adolescence is a very complex and crucial phase of life, where teenagers are caught up in their own web of personal strivings, such as the issues of being, belonging and becoming. Such strivings play a pivotal role in determining their quality of life. Further whether these intrinsic motives (i.e. 3Bs being, belonging and becoming) are being influenced by gender stereotypes is a big issue for the psychologists to explore. Thus the current study is an attempt to explore and compare the levels of being, belonging and becoming (comprising of overall QOL) among male and female adolescents. A purposive sample of 98 adolescents aged 16-18 years, both male (n=44) and female (n=54) was drawn from the colleges of Rewari and Gurgaon districts of Haryana. For measuring personal strivings, Quality Of Life Profile for Adolescent Version Questionnaire (Raphael, Rukholm, Brown, Hill-Bailey & Donato, 1996) was used. Descriptive and inferential statistics were used to assess the levels of being, belonging and becoming and overall quality of life and gender comparison was done on these variables. Results indicated adequate level of personal strivings leading to overall good quality of life among adolescents (total as well as in both male and female separately). Both males and females have similar levels of quality of life. However, females superseded males in spiritual being and community belonging.

scholarly journals Implantação de Terapia Comunitária online: tecnologia do cuidado em tempos de pandemia

2020 ◽  
Vol 16 (esp. 1) ◽  
pp. 393-408
Author(s):  
André Luiz Pereira Silva ◽  
Doralice Otaviano ◽  
Fernanda Cruz Vieira Ferreira ◽  
Jurema Valkiria Otaviano ◽  
Jussara Otaviano ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Global Health ◽  
Social Determinants Of Health ◽  
Social Determinants ◽  
Health Crisis ◽  
The Social ◽  
The Individual ◽  
Psychosocial Crisis

Suddenly in March 2020 we found ourselves confined and isolated in our homes, due to a global health crisis arising from a pandemic, caused by the contamination of a virus called COVID-19. This health crisis also generated a crisis in the social determinants of health, especially those related to the economy, education and culture. But it also generated another crisis, the psychosocial crisis, where populations affected by the effects of mental damage caused by the pandemic and isolation, showed important signs of stress. It is in this scenario that the Integrative Community Therapy, previously carried out in person, is renewed and reinvented. This article reports on the experience of implementing the Integrative Community Therapy online in Brazil and presents the results of the Afinando Vidas Pole in the contribution of improving the quality of life and the individual and collective mental health of the Brazilian population.

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