Computational Neuropsychology

Author(s):  
Thomas D. Parsons ◽  
Robert L. Kane

Other chapters in this volume focus on the use of technology to enhance and expand the field of neuropsychology. Some of the enhancements are natural outgrowths of trends present in society at large and involve updating the assessment process to make it more efficient and reliable. Computerized approaches to assessment frequently use off-the-shelf technology, in some cases to administer traditional style tests, while in others to present tasks not readily accomplished with test booklets and paper (see Section II of this book on “Beyond Paper-and-Pencil Assessment”). The computer has also permitted the implementation of new testing paradigms such as scenario-based assessment and the use of virtual reality (see Section III: “Domain and Scenario-based Assessment”). The use of the computer has also made possible efforts to expand access to care through the development of efficient test batteries and telemedicine-based assessment (see Chapter 5 on Teleneuropsychology). The use of computers, the ability to implement life-like scenarios in a controlled environment, and tele­medicine will also expand available approaches to cognitive remediation with cellphones augmenting the ability of individuals to engage in self-monitoring. The integration of neuroimaging into the assessment process was clearly presented in the chapter in this volume by Erin Bigler (see also Section IV of this book on “Integrating Cognitive Assessment with Biological Metrics”). An addi­tional role for neuroimaging is the use of its ever evolving techniques and methods to model neural networks and to refine our understanding of how the brain works and how best to conceptualize cognitive domains. Both neuroimaging to model neural networks and the role of neuroinformatics will be discussed in the remaining sections of this chapter on some prospects for a future computational neuropsychology. Technological advances in neuroimaging of brain structure and function offer great potential for revolutionizing neuropsychology (Bilder, 2011). While neuroimaging has taken advantage of advances in computerization and neuroinfor­matics, neuropsychological assessments are outmoded and reflect nosological attempts at classification that occurred prior to contemporary neuroimaging (see Chapter 13 in this volume).

Agriculture ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 497
Author(s):  
Sebastian Kujawa ◽  
Gniewko Niedbała

Artificial neural networks are one of the most important elements of machine learning and artificial intelligence. They are inspired by the human brain structure and function as if they are based on interconnected nodes in which simple processing operations take place. The spectrum of neural networks application is very wide, and it also includes agriculture. Artificial neural networks are increasingly used by food producers at every stage of agricultural production and in efficient farm management. Examples of their applications include: forecasting of production effects in agriculture on the basis of a wide range of independent variables, verification of diseases and pests, intelligent weed control, and classification of the quality of harvested crops. Artificial intelligence methods support decision-making systems in agriculture, help optimize storage and transport processes, and make it possible to predict the costs incurred depending on the chosen direction of management. The inclusion of machine learning methods in the “life cycle of a farm” requires handling large amounts of data collected during the entire growing season and having the appropriate software. Currently, the visible development of precision farming and digital agriculture is causing more and more farms to turn to tools based on artificial intelligence. The purpose of this Special Issue was to publish high-quality research and review papers that cover the application of various types of artificial neural networks in solving relevant tasks and problems of widely defined agriculture.


Author(s):  
Reginald B. Adams ◽  
Daniel N. Albohn ◽  
Kestutis Kveraga

In this chapter, we discuss prospects for a future computational neuropsychology. Computerized approaches to assessment, the ability to implement life-like scenarios in a controlled virtual environment, and teleneuropsychology offer promise for expanding available approaches to cognitive remediation and self-monitoring. Computational models are also available increasingly for integrating neuroimaging into the assessment process. Neuropsychologists can use neuroimaging to develop new frameworks for neuropsychological testing that are rooted in the current evidence base on large-scale brain system interactions. This will allow for traditional assessment of discrete areas of neurocognitive functioning to be brought in line with recent findings that highly nuanced relations exist among brain networks. Furthermore, the new findings from systems neuroscience may allow for the development of neuropsychological assessments with greater accuracy and increased targeted testing. Neuroinfomatic approaches offer computational neuropsychology an approach to knowledge sharing via well-defined neuropsychological ontologies and collaborative knowledgebases.


Author(s):  
Robert L. Kane ◽  
Thomas D. Parsons

The word disruptive has become associated with the age of technology. The connotations of this term have changed drastically from years ago, when in schools it was associated with the type of behavior that would result in a trip to the principal’s office. In the 21st century, “disruptive” often refers to changes that markedly affect and reshape the way things are done, opening up new approaches that change the way we live and function. Computers in various forms, from desktop systems to handheld devices and mobile phones, have played a large role in changing the way we live and work. Researchers no longer spend days at computer centers running study statistics and now can accomplish far more sophisticated analyses using notebook computers. Despite the dramatic changes technology has made in most phases of life, its impact on the practice of clinical neuropsychology has been minimal. It is fair to say that neuropsychologists have increased their use of computers for patient assessment and that some traditional test measures have been adopted for computers, simplifying the administration and scoring process. A number of tests have been developed and designed for computer administration. While computer use has increased especially in specific areas, such as aviation, pharmaceutical studies, and in evaluating concussion both in sports and in the military, the potential use of computers and other technologies to augment assessment has barely been exploited. The goal of this volume is to present ideas and accomplished work demonstrating the use of technology to augment the neuropsychological assessment of patients. Some of the ideas presented in the introduction are forward thinking, incorporate the use of advanced technology, and are potentially disruptive. Others represent incremental changes, but changes that take obvious advantage of using technology to modernize and streamline the assessment process. The introduction reviews the current state of technology in neuropsychology and sets the stage for the succeeding chapters.


2016 ◽  
Vol 116 (5) ◽  
pp. 2093-2104 ◽  
Author(s):  
Christopher M. Filley ◽  
R. Douglas Fields

Whereas the cerebral cortex has long been regarded by neuroscientists as the major locus of cognitive function, the white matter of the brain is increasingly recognized as equally critical for cognition. White matter comprises half of the brain, has expanded more than gray matter in evolution, and forms an indispensable component of distributed neural networks that subserve neurobehavioral operations. White matter tracts mediate the essential connectivity by which human behavior is organized, working in concert with gray matter to enable the extraordinary repertoire of human cognitive capacities. In this review, we present evidence from behavioral neurology that white matter lesions regularly disturb cognition, consider the role of white matter in the physiology of distributed neural networks, develop the hypothesis that white matter dysfunction is relevant to neurodegenerative disorders, including Alzheimer's disease and the newly described entity chronic traumatic encephalopathy, and discuss emerging concepts regarding the prevention and treatment of cognitive dysfunction associated with white matter disorders. Investigation of the role of white matter in cognition has yielded many valuable insights and promises to expand understanding of normal brain structure and function, improve the treatment of many neurobehavioral disorders, and disclose new opportunities for research on many challenging problems facing medicine and society.


2017 ◽  
Vol 30 (1) ◽  
pp. 7-12 ◽  
Author(s):  
Carmen Rodríguez Cerdeira ◽  
Elena Sánchez-Blanco ◽  
Beatriz Sánchez-Blanco ◽  
Jose Luis González-Cespón ◽  

Psychiatric evaluation presents a significant challenge because it conceptually integrates the input from multiple psychopathological approaches. Recent technological advances in the study of protein structure, function, and interactions have provided a breakthrough in the diagnosis and treatment of mood disorders (MD), and have identified novel biomarkers to be used as indicators of normal and disease states or response to drug treatment. The investigation of biomarkers for psychiatric disorders, such as enzymes (catechol-O-methyl transferase and monoamine oxidases) or neurotransmitters (dopamine, serotonin, norepinephrine) and their receptors, particularly their involvement in neuroendocrine activity, brain structure, and function, and response to psychotropic drugs, should facilitate the diagnosis of MD. In clinical settings, prognostic biomarkers may be revealed by analyzing serum, saliva, and/or the cerebrospinal fluid, which should promote timely diagnosis and personalized treatment. The mechanisms underlying the activity of most currently used drugs are based on the functional regulation of proteins, including receptors, enzymes, and metabolic factors. In this study, we analyzed recent advances in the identification of biomarkers for MD, which could be used for the timely diagnosis, treatment stratification, and prediction of clinical outcomes.


2019 ◽  
Author(s):  
Elisabeth A. Wilde ◽  
Emily L. Dennis ◽  
David F Tate

The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium brings together researchers from around the world to try to identify the genetic underpinnings of brain structure and function, along with robust, generalizable effects of neurological and psychiatric disorders. The recently-formed ENIGMA Brain Injury working group includes 8 subgroups, based largely on injury mechanism and patient population. This introduction to the special issue summarizes the history, organization, and objectives of ENIGMA Brain Injury, and includes a discussion of strategies, challenges, opportunities and goals common across 6 of the subgroups under the umbrella of ENIGMA Brain Injury. The following articles in this special issue, including 6 articles from different subgroups, will detail the challenges and opportunities specific to each subgroup.


Sensors ◽  
2021 ◽  
Vol 21 (9) ◽  
pp. 3279
Author(s):  
Maria Habib ◽  
Mohammad Faris ◽  
Raneem Qaddoura ◽  
Manal Alomari ◽  
Alaa Alomari ◽  
...  

Maintaining a high quality of conversation between doctors and patients is essential in telehealth services, where efficient and competent communication is important to promote patient health. Assessing the quality of medical conversations is often handled based on a human auditory-perceptual evaluation. Typically, trained experts are needed for such tasks, as they follow systematic evaluation criteria. However, the daily rapid increase of consultations makes the evaluation process inefficient and impractical. This paper investigates the automation of the quality assessment process of patient–doctor voice-based conversations in a telehealth service using a deep-learning-based classification model. For this, the data consist of audio recordings obtained from Altibbi. Altibbi is a digital health platform that provides telemedicine and telehealth services in the Middle East and North Africa (MENA). The objective is to assist Altibbi’s operations team in the evaluation of the provided consultations in an automated manner. The proposed model is developed using three sets of features: features extracted from the signal level, the transcript level, and the signal and transcript levels. At the signal level, various statistical and spectral information is calculated to characterize the spectral envelope of the speech recordings. At the transcript level, a pre-trained embedding model is utilized to encompass the semantic and contextual features of the textual information. Additionally, the hybrid of the signal and transcript levels is explored and analyzed. The designed classification model relies on stacked layers of deep neural networks and convolutional neural networks. Evaluation results show that the model achieved a higher level of precision when compared with the manual evaluation approach followed by Altibbi’s operations team.


2021 ◽  
Vol 11 (5) ◽  
pp. 2068
Author(s):  
William Villegas-Ch. ◽  
Xavier Palacios-Pacheco ◽  
Milton Roman-Cañizares ◽  
Sergio Luján-Mora

Currently, the 2019 Coronavirus Disease pandemic has caused serious damage to health throughout the world. Its contagious capacity has forced the governments of the world to decree isolation and quarantine to try to control the pandemic. The consequences that it leaves in all sectors of society have been disastrous. However, technological advances have allowed people to continue their different activities to some extent while maintaining isolation. Universities have great penetration in the use of technology, but they have also been severely affected. To give continuity to education, universities have been forced to move to an educational model based on synchronous encounters, but they have maintained the methodology of a face-to-face educational model, what has caused several problems in the learning of students. This work proposes the transition to a hybrid educational model, provided that this transition is supported by data analysis to identify the new needs of students. The knowledge obtained is contrasted with the performance presented by the students in the face-to-face modality and the necessary parameters for the transition to this modality are clearly established. In addition, the guidelines and methodology of online education are considered in order to take advantage of the best of both modalities and guarantee learning.


2012 ◽  
Vol 24 (2) ◽  
pp. 91-100 ◽  
Author(s):  
Triptish Bhatia ◽  
Akhilesh Agarwal ◽  
Gyandeepak Shah ◽  
Joel Wood ◽  
Jan Richard ◽  
...  

Background:Yoga therapy (YT) improves cognitive function in healthy individuals, but its impact on cognitive function among persons with schizophrenia (SZ) has not been investigated.Objective:To evaluate the adjunctive YT for cognitive domains impaired in SZ.Methods:Patients with SZ received YT or treatment as usual (TAU;n= 65,n= 23, respectively). Accuracy and speed for seven cognitive domains were assessed using a computerised neurocognitive battery (CNB), thus minimising observer bias. Separately, YT was evaluated among patients with bipolar I disorder (n= 40), major depressive disorder (n= 37) and cardiology outpatients (n= 68). All patients also received routine pharmacotherapy. Patients were not randomised to YT or TAU.Results:In comparison with the SZ/TAU group, the SZ/YT group showed significantly greater improvement with regard to measures of attention following corrections for multiple comparisons; the changes were more prominent among the men. In the other diagnostic groups, differing patterns of improvements were noted with small-to-medium effect sizes.Conclusions:Our initial analyses suggest nominally significant improvement in cognitive function in SZ with adjunctive therapies such as YT. The magnitude of the change varies by cognitive domain and may also vary by diagnostic group.


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