Error Detection and Representational Mechanisms

2020 ◽  
pp. 287-318
Author(s):  
Krystyna Bielecka ◽  
Marcin Miłkowski
Keyword(s):  
Mental Representation ◽  
Error Detection ◽  
Recent Experiment ◽  
Scientific Research ◽  
Zebra Finches ◽  
Biological Functions ◽  
Semantic Value ◽  
Discrepancy Detection ◽  
Detection Mechanisms

This chapter defends a mechanistic and teleosemantic view of naturalized intentionality that underlies the role of error detection via coherence checking. Representational mechanisms serve the biological functions of representing, which are related to the semantic value of representation: its truth or falsity, its being vacuous or satisfied, or its accuracy. If representational mechanisms contain (or interact with) error-detection mechanisms, the semantic value of representation is causally relevant. As long as semantic value is causally relevant in cognitive explanations, the content of representation is arguably causally relevant, which vindicates the notion of mental representation in contemporary scientific research. Error detection is understood mechanistically in terms of coherence checking, which is purely computational and does not presuppose any semantic function. This chapter analyzes this conceptually and demonstrates that this account is descriptively adequate by citing a recent experiment on zebra finches, even though discrepancy detection is not always related to intentionality.

scholarly journals Attitudes of second language students towards self-editing their own written texts

2010 ◽  
Vol 1 (1) ◽  
Author(s):  
Daniel Kasule ◽  
Violet B. Lunga
Keyword(s):  
Error Detection ◽  
Social Practice ◽  
Active Agent ◽  
Class Discussion ◽  
Student Autonomy ◽  
Written Texts ◽  
Detection Mechanisms ◽  
Socially Situated ◽  
Vital Element

Recognizing students’ deliberate e!orts to minimize errors in their written texts is valuable in seeing them as responsible active agents in text creation. This paper reports on a brief survey of the attitudes towards self-editing of seventy university students using a questionnaire and class discussion. The context of the study is characterized by its emphasis on evaluating the finished written product. Findings show that students appreciate the role of self-editing in minimizing errors in their texts and that it helps in eventually producing well-written texts. Conceptualizing writing as discourse and therefore as social practice leads to an understanding of writers as socially-situated actors; repositions the student writer as an active agent in text creation; and is central to student-centred pedagogy. We recommend the recognition of self-editing as a vital element in the writing process and that additional error detection mechanisms namely peers, the lecturer, and the computer, increase student autonomy.

A reconnaissance of tropical resources during Revolutionary years: the role of the Paris Museum d'Histoire Naturelle

1991 ◽  
Vol 18 (3) ◽  
pp. 333-362 ◽  
Author(s):  
MADELEINE LY-TIO-FANE
Keyword(s):  
South Africa ◽  
Natural History ◽  
Scientific Research ◽  
Extensive Literature ◽  
War Of Independence ◽  
Leading Role ◽  
Scientific Principles ◽  
Set Up ◽  
Joseph Ii

SUMMARY The recent extensive literature on exploration and the resulting scientific advances has failed to highlight the contribution of Austrian enterprise to the study of natural history. The leading role of Joseph II among the neutral powers which assumed the carrying trade of the belligerents during the American War of Independence, furthered the development of collections for the Schönbrunn Park and Gardens which had been set up on scientific principles by his parents. On the conclusion of peace, Joseph entrusted to Professor Maerter a world-encompassing mission in the course of which the Chief Gardener Franz Boos and his assistant Georg Scholl travelled to South Africa to collect plants and animals. Boos pursued the mission to Isle de France and Bourbon (Mauritius and Reunion), conveyed by the then unknown Nicolas Baudin. He worked at the Jardin du Roi, Pamplemousses, with Nicolas Cere, or at Palma with Joseph Francois Charpentier de Cossigny. The linkage of Austrian and French horticultural expertise created a situation fraught with opportunities which were to lead Baudin to the forefront of exploration and scientific research as the century closed in the upheaval of the Revolutionary Wars.

A scientific research study on the management of Manyasthamba (Cervical Spondylosis) with Nasya and Nasapana

2019 ◽  
Vol 4 (04) ◽  
Author(s):  
Unnikrishnan V S ◽  
Prashanth A S ◽  
Madhusudan Kulkarni
Keyword(s):  
Spinal Cord ◽  
Clinical Data ◽  
Food Habits ◽  
Cervical Spondylosis ◽  
Research Study ◽  
Weight Bearing ◽  
Scientific Research ◽  
Modern Era ◽  
Treatment Aspect

The science of life Ayurveda, not only deals with the prevention of diseases by maintaining health but also with the alleviation of diseases. In this ultra modern era due to change in lifestyles, sedentary works and food habits, people are unable to follow the Dinacharya and Ritucharya as explained in the classics, which may lead to different diseases. Due to improper postural habits, weight bearing and other unwholesome diets and habits there are higher the chances of discomfort and disease pertaining to spinal cord. Manyasthambha is one such condition that disturbs a big population due to today’s alterations in lifestyle. Here an effort is made to study and understand the role of Nasya Karma, Nasaapana and Shamanaushadhi like Vyoshadi Guggulu in the treatment aspect of this disease. Nasya Karma and Nasaapana provided highly significant results in all the symptoms of Manyasthambha. As per the clinical data, ‘Nasaapana is found to be more effective than Nasya Karma’. So it can be concluded that better results can be obtained with Shaddharana Yoga as Amapachana, Nasaapana with Mashabaladi Kwatha followed by Vyoshadi Guggulu as Shamanoushadhi.

scholarly journals Behind an Accelerated Scientific Research Career: Dynamic Interplay of Endogenous and Exogenous Forces in Talent Development

2020 ◽  
Vol 10 (9) ◽  
pp. 220
Author(s):  
David Yun Dai ◽  
Xian (Stella) Li
Keyword(s):  
Professional Training ◽  
Scientific Research ◽  
Talent Development ◽  
Early College ◽  
Research Career ◽  
Learning And Development ◽  
Endogenous Factors ◽  
Exogenous Factors ◽  
Dynamic Interplay

This study looks at the educational experiences, from the preschool years to advanced professional training in STEM fields, of a targeted sample of 10 (7 male, 3 female) early college entrants in China who later became professors at prestigious USA research universities. The purpose of the study was to find out (1) what some identifiable endogenous factors were about these individuals that facilitated the success of their accelerated learning and development; (2) what kinds of exogenous factors (e.g., environmental opportunities, resources, support) they experienced from childhood to adulthood that enhanced the successful acceleration experience; and (3) how these endogenous and exogenous factors facilitated their developmental transitions every step of the way, especially from the role of a student to that of an aspiring scientist. These questions are addressed in light of evolving complexity theory. Retrospective interviews were used for data collection. Thematic analysis of the codes from interview data yielded a conceptual map. A distinct set of endogenous and exogenous factors at different developmental junctures were identified, and their dynamic interplay was delineated to account for accelerated trajectories toward a scientific research career. The theoretical significance and practical implications of the study for talent development in science are discussed.

scholarly journals Regulatory Role of microRNAs Targeting the Transcription Co-Factor ZNF521 in Normal Tissues and Cancers

2021 ◽  
Vol 22 (16) ◽  
pp. 8461
Author(s):  
Emanuela Chiarella ◽  
Annamaria Aloisio ◽  
Stefania Scicchitano ◽  
Heather Mandy Bond ◽  
Maria Mesuraca
Keyword(s):  
Transcription Factor ◽  
Molecular Mechanisms ◽  
Transitional Cell ◽  
Biological Functions ◽  
Aberrant Expression ◽  
Normal Tissues ◽  
Novel Mirna ◽  
Mirna Expression Profiling ◽  
Mirna Deregulation

Powerful bioinformatics tools have provided a wealth of novel miRNA–transcription factor networks crucial in controlling gene regulation. In this review, we focus on the biological functions of miRNAs targeting ZNF521, explaining the molecular mechanisms by which the dysregulation of this axis contributes to malignancy. ZNF521 is a stem cell-associated co-transcription factor implicated in the regulation of hematopoietic, neural, and mesenchymal stem cells. The aberrant expression of ZNF521 transcripts, frequently associated with miRNA deregulation, has been detected in several tumors including pancreatic, hepatocellular, gastric, bladder transitional cell carcinomas as well as in breast and ovarian cancers. miRNA expression profiling tools are currently identifying a multitude of miRNAs, involved together with oncogenes and TFs in the regulation of oncogenesis, including ZNF521, which may be candidates for diagnostic and prognostic biomarkers of cancer.

First record of albino lowland tapirs (Tapirus terrestris Linnaeus 1758) in an important Brazilian Atlantic Forest hotspot

Mammalia ◽  
2020 ◽  
Vol 84 (6) ◽  
pp. 601-604
Author(s):  
Mariana Bueno Landis ◽  
Luciano Candisani ◽  
Leticia Prado Munhoes ◽  
João Carlos Zecchini Gebin ◽  
Frineia Rezende ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Atlantic Forest ◽  
Scientific Research ◽  
First Record ◽  
Brazilian Atlantic Forest ◽  
Tapirus Terrestris

AbstractAlbinism is the absence of pigmentation or coloration and is rarely found in nature. In this study we examined photos and videos obtained by cameras traps in the Legado das Águas Reserve. In the images, we identified two albino lowland tapirs. The results highlight the necessity of understanding the genetic diversity of lowland tapir populations and the important role of the professional photography associated with scientific research.

scholarly journals The dynamic behavior of lipid droplets in the pre-metastatic niche

2020 ◽  
Vol 11 (11) ◽  
Author(s):  
Chunliang Shang ◽  
Jie Qiao ◽  
Hongyan Guo
Keyword(s):  
Tumor Cells ◽  
Immune Cells ◽  
Stromal Cells ◽  
Lipid Droplets ◽  
Metastatic Tumor ◽  
Current Evidence ◽  
Biological Functions ◽  
Metastatic Niche ◽  
Niche Formation

AbstractThe pre-metastatic niche is a favorable microenvironment for the colonization of metastatic tumor cells in specific distant organs. Lipid droplets (LDs, also known as lipid bodies or adiposomes) have increasingly been recognized as lipid-rich, functionally dynamic organelles within tumor cells, immune cells, and other stromal cells that are linked to diverse biological functions and human diseases. Moreover, in recent years, several studies have described the indispensable role of LDs in the development of pre-metastatic niches. This review discusses current evidence related to the biogenesis, composition, and functions of LDs related to the following characteristics of the pre-metastatic niche: immunosuppression, inflammation, angiogenesis/vascular permeability, lymphangiogenesis, organotropism, reprogramming. We also address the function of LDs in mediating pre-metastatic niche formation. The potential of LDs as markers and targets for novel antimetastatic therapies will be discussed.

scholarly journals The role of m6A modification in the biological functions and diseases

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Xiulin Jiang ◽  
Baiyang Liu ◽  
Zhi Nie ◽  
Lincan Duan ◽  
Qiuxia Xiong ◽  
...  
Keyword(s):  
Cancer Progression ◽  
Molecular Mechanisms ◽  
Target Genes ◽  
Rna Modification ◽  
Biological Functions ◽  
Rna Methylation ◽  
Downstream Target ◽  
Different Types ◽  
M6a Rna Methylation

AbstractN6-methyladenosine (m6A) is the most prevalent, abundant and conserved internal cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells. m6A modification is modified by the m6A methyltransferases, or writers, such as METTL3/14/16, RBM15/15B, ZC3H3, VIRMA, CBLL1, WTAP, and KIAA1429, and, removed by the demethylases, or erasers, including FTO and ALKBH5. It is recognized by m6A-binding proteins YTHDF1/2/3, YTHDC1/2 IGF2BP1/2/3 and HNRNPA2B1, also known as “readers”. Recent studies have shown that m6A RNA modification plays essential role in both physiological and pathological conditions, especially in the initiation and progression of different types of human cancers. In this review, we discuss how m6A RNA methylation influences both the physiological and pathological progressions of hematopoietic, central nervous and reproductive systems. We will mainly focus on recent progress in identifying the biological functions and the underlying molecular mechanisms of m6A RNA methylation, its regulators and downstream target genes, during cancer progression in above systems. We propose that m6A RNA methylation process offer potential targets for cancer therapy in the future.

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