Scales

Author(s):  
Robin Hanson

Can we say anything about the specific speeds at which ems can run? Because of brain parallelism, the cost of running an em should be nearly proportional to speed over a wide range of speeds. The upper limit of this proportional-cost em speed range is the “top cheap” speed, that is, the highest speed at which the cost is still nearly proportional to speed. To estimate this speed, we must consider how simulated neurons in em brains might both send faster signals, and more quickly compute what signals to send. Human brain neuron fibers send signals at speeds ranging from 0.5 to 120 meters per second. In contrast, signal speeds in electronic circuit boards today are typically about half the speed of light. If signals in em brains move at electronics speeds, that would be between one million and 300 million times faster than neuron signals. If signal delays are the limiting factor in em brain speed, then this ratio gives an estimate of the maximum speedup possible, at least if em brains have the same spatial size as human brains. proportionally larger speedups are possible if em brains can be made proportionally smaller. Regarding the computation of when to fire a simulated neuron, note that real neurons usually seem to take at least 20 milliseconds to react ( Tovee 1994 ), while even today electronic circuits can switch 10 billion times faster, in one-and-a-half trillionths of a second ( deal et al. 2010 ). A key question is thus: how many electronic circuit cycles does it take to execute a parallel computer program that emulates the firing of a single neuron? For example, if there were an algorithm that could compute a neuron firing in 10 000 of these fastest-known circuit cycles, then an emulation based on this algorithm would run a million times faster than the human brain. As quite complex parallel computer programs can be run in 10 000 cycles, em speedups of at least one million times seem feasible, provided that energy and cooling are cheap enough to profitably allow the use of these fastest electronic circuits. When energy and cooling are more strongly limiting factors, however, the top cheap speed could be slower.

Author(s):  
P. Sridhar Acharya ◽  
P. S. Aithal

The energy from the sun is abundant for essential requirements of every home. But due to technological reasons, it is not so easy to use the solar energy by converting it into electrical energy efficiently in all places. The important factors which would be affecting the efficiency of the solar panels (which is presently in the range of 20% to 30%,) are the cost involved in implementing the same at each house, lack of knowledge on investment return etc. The semiconductor technology for fabricating solar cells contributes to the performance. The impurities in the semiconductor technology, the heat from the sunlight are the negative factors for the performance. The variation in the angle of sunlight incident from morning to evening is also a negative factor for the performance. The climate condition of the environment like cloudy weather which limits the sunlight falling into the panel is another limiting factor. Considering all these limiting factors this paper proposes the different modes of installation of solar energy. This paper contains the normal power requirement of the house and methods for either partial or complete solar energy installation to the individual house.


2021 ◽  
Vol 11 (3) ◽  
pp. 342 ◽  
Author(s):  
Balázs Szalkai ◽  
Bálint Varga ◽  
Vince Grolmusz

Graph theory in the last two decades penetrated sociology, molecular biology, genetics, chemistry, computer engineering, and numerous other fields of science. One of the more recent areas of its applications is the study of the connections of the human brain. By the development of diffusion magnetic resonance imaging (diffusion MRI), it is possible today to map the connections between the 1–1.5 cm2 regions of the gray matter of the human brain. These connections can be viewed as a graph. We have computed 1015-vertex graphs with thousands of edges for hundreds of human brains from one of the highest quality data sources: the Human Connectome Project. Here we analyze the male and female braingraphs graph-theoretically and show statistically significant differences in numerous parameters between the sexes: the female braingraphs are better expanders, have more edges, larger bipartition widths, and larger vertex cover than the braingraphs of the male subjects. These parameters are closely related to the quality measures of highly parallel computer interconnection networks: the better expanding property, the large bipartition width, and the large vertex cover characterize high-quality interconnection networks. We apply the data of 426 subjects and demonstrate the statistically significant (corrected) differences in 116 graph parameters between the sexes.


Energies ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 294
Author(s):  
Andrius Kulsinskas ◽  
Petar Durdevic ◽  
Daniel Ortiz-Arroyo

Interior and exterior wind turbine blade inspections are necessary to extend the lifetime of wind turbine generators. The use of unmanned vehicles is an alternative to exterior wind turbine blade inspections performed by technicians that require the use of cranes and ropes. Interior wind turbine blade inspections are even more challenging due to the confined spaces, lack of illumination, and the presence of potentially harmful internal structural components. Additionally, the cost of manned interior wind turbine blade inspections is a major limiting factor. This paper analyses all aspects of the viability of using manually controlled or autonomous aerial vehicles for interior wind turbine blade inspections. We discuss why the size, weight, and flight time of a vehicle, in addition to the structure of the wind turbine blade, are the main limiting factors in performing internal blade inspections. We also describe the design issues that must be considered to provide autonomy to unmanned vehicles and the control system, the sensors that can be used, and introduce some of the algorithms for localization, obstacle avoidance and path planning that are best suited for the task. Lastly, we briefly describe which non-destructive test instrumentation can be used for the purpose.


2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Jon Kepa Izaguirre ◽  
Leire Barañano ◽  
Sonia Castañón ◽  
José A. L. Santos ◽  
M. Teresa Cesário ◽  
...  

AbstractThe management of municipal solid waste is a major logistic and environmental problem worldwide. Nonetheless, the organic fraction of municipal solid waste (OFMSW) is a valuable source of nutrients which can be used for a variety of purposes, according to the Circular Economy paradigm. Among the possible applications, the bioproduction of a biodegradable polyester, poly(3-hydroxybutyrate) [P(3HB)], using OFMSW as carbon platform is a promising strategy. Here, an economic and environmental assessment of bacterial P(3HB) production from OFMSW is presented based on previously published results. The SuperPro Designer® software was used to simulate P(3HB) production under our experimental parameters. Two scenarios were proposed depending on the fermentation medium: (1) enzymatic hydrolysate of OFMSW supplemented with glucose and plum waste juice; and (2) basal medium supplemented with glucose and plum waste juice. According to our results, both scenarios are not economically feasible under our experimental parameters. In Scenario 1, the low fermentation yield, the cost of the enzymes, the labour cost and the energy consumption are the factors that most contribute to that result. In Scenario 2, the cost of the extraction solvent and the low fermentation yield are the most limiting factors. The possibility of using process waste as raw material for the generation of other products must be investigated to enhance economic feasibility. From an environmental viewpoint, the photochemical oxidation potential (derived from the use of anisole as extraction solvent) and the generation of acid rain and global warming effect (caused by the burning of fuels for power generation) are the most relevant impacts associated to P(3HB) production under our experimental parameters.


2021 ◽  
Author(s):  
Song-Lin Ding ◽  
Joshua J. Royall ◽  
Phil Lesnar ◽  
Benjamin A.C. Facer ◽  
Kimberly A. Smith ◽  
...  

Increasing interest in studies of prenatal human brain development, particularly using new single-cell genomics and anatomical technologies to create cell atlases, creates a strong need for accurate and detailed anatomical reference atlases. In this study, we present two cellular-resolution digital anatomical atlases for prenatal human brain at post-conceptional weeks (PCW) 15 and 21. Both atlases were annotated on sequential Nissl-stained sections covering brain-wide structures on the basis of combined analysis of cytoarchitecture, acetylcholinesterase staining and an extensive marker gene expression dataset. This high information content dataset allowed reliable and accurate demarcation of developing cortical and subcortical structures and their subdivisions. Furthermore, using the anatomical atlases as a guide, spatial expression of 37 and 5 genes from the brains respectively at PCW 15 and 21 was annotated, illustrating reliable marker genes for many developing brain structures. Finally, the present study uncovered several novel developmental features, such as the lack of an outer subventricular zone in the hippocampal formation and entorhinal cortex, and the apparent extension of both cortical (excitatory) and subcortical (inhibitory) progenitors into the prenatal olfactory bulb. These comprehensive atlases provide useful tools for visualization, targeting, imaging and interpretation of brain structures of prenatal human brain, and for guiding and interpreting the next generation of cell census and connectome studies.


2016 ◽  
Vol 15 (2) ◽  
pp. 20
Author(s):  
Piyachat Wattanachai ◽  
Christian Antonio ◽  
Susan Roces

The possibility of implementing microwave technology to photoresist film curing which is a major process in the production of electronic printed circuit boards (PCB) was investigated and compared with a conventional curing method, e.g. UV lithography. Since both techniques involved irradiation, hot plate curing which relies on thermal conduction was undertaken to study the effect of a heat transfer approach. Two film thicknesses were studied, i.e. 0.0012 and 0.002 inch, and the effects of curing power and time were investigated. Thermal properties, i.e. percent cure, glass transition temperature (Tg), composition and degradation temperature (Td), were evaluated using a Differential Scanning Calorimeter (DSC) and Thermogravimetric Analysis (TGA) and it was found that the commercial UV irradiation was sufficient to completely cure the thin film but only reached 76% cure for the thicker film, resulting in a lower Tg. The results show that the required processing conditions using a conventional household microwave to obtain almost complete curing were 1,000 Watts and 10 minutes curing time. In addition, improved curing was achieved in the thicker film because microwave can transmit into polar materials whereas UV cannot penetrate very far into the material. The hot plate curing was observed to produce a higher degree of curing and Tg, however, the uniformity of heating was found to be a major limiting factor of this technique. Slight differences in decomposition profiles of the films cured by different techniques implied slight differences in molecular structures. Compared to UV and hot plate curing, microwave technology was demonstrated as a potential curing technique in the production of PCBs due to its ability to efficiently cure thick films resulting in a strong material with high Tg. To apply the technique to other processes, optimal conditions, i.e. power and time, should be further investigated as well as the prevention of hot spots.


2021 ◽  
Vol 4 (2) ◽  
pp. 94-105
Author(s):  
Koko Tampubolon ◽  
Bagus Fitra Azmi ◽  
Perdana Andriano Tamba ◽  
Ayu Widya Lestari ◽  
Kamaruddin Kamaruddin ◽  
...  

Introduction: The research was aimed to obtain information on the impact of omission one test fertilization as a determination limiting factors for the growth and biomass of maize in variety Bonanza F1. Materials and Methods: The research was located in the experimental field, Faculty of Agriculture and Animal Husbandry, Universitas Tjut Nyak Dhien, Medan from December 2020 until February 2021. The research was applied by Randomized Block Design in non-factorial through fertilization of omission one test that has been converted (urea : SP-36 : KCl = 0.75 : 0.50 : 0.125 g polybag-1). The treatment of this research include P0 = non-fertilization; P1= N+P+K; P2= P+K; P3= N+K; P4= N+P using three replications. The parameters include plant height, leaf growth, total fresh weight, total dry weight, and the percentage of relative yield then processed using ANOVA and continued with DMRT at 5% ± standard error with SPSS v.20 software. Results: Informed that the omission one test technique significantly improved all the characteristics of maize in the variety Bonanza F1. The highest increase in plant height was found in the N+P of 83.65%, meanwhile, the highest leaf and biomass growth characters were found in N+P+K, ranged of 50.00 to 177.81% and 487.60 to 507.37%, respectively. It was obtained that the limiting factor for the maize growth in variety Bonanza F1 was found in the un-fertilization of nitrogen.


2016 ◽  
Vol 10 (1) ◽  
pp. 31
Author(s):  
Mubekti Mubekti

The study is the preliminary research aiming to apply the usefulness of the GISsystem for classifying suitability of region to the agricultural mechanization. Simplebasic theory of GIS and classification of agricultural mechanization were presented.Nine physical and non-physical parameters as limiting factors were defined and aweight of each parameter was calculated in order to know how far its effect to theagricultural mechanization practice. Data coming from several types, ie: numeric,vector and remote sensing (raster) were prepared to support the process. Twoordoes consisting of five classes were employed to extract suitability classificationof each District in Jawa Barat dan Banten Province. The results show that tendistricts are classified into suitable for applying agricultural mechanization, and therest ten districts are classified into not suitable. Depending on the dynamic characterof limiting factor, suitability class would possibly change along the time. Saveralconclusions and advices for improving research are given.


2021 ◽  
pp. 1-9
Author(s):  
Daniel Gebrezgiabhier ◽  
Yang Liu ◽  
Adithya S. Reddy ◽  
Evan Davis ◽  
Yihao Zheng ◽  
...  

OBJECTIVEEndovascular removal of emboli causing large vessel occlusion (LVO)–related stroke utilizing suction catheter and/or stent retriever technologies or thrombectomy is a new standard of care. Despite high recanalization rates, 40% of stroke patients still experience poor neurological outcomes as many cases cannot be fully reopened after the first attempt. The development of new endovascular technologies and techniques for mechanical thrombectomy requires more sophisticated testing platforms that overcome the limitations of phantom-based simulators. The authors investigated the use of a hybrid platform for LVO stroke constructed with cadaveric human brains.METHODSA test bed for embolic occlusion of cerebrovascular arteries and mechanical thrombectomy was developed with cadaveric human brains, a customized hydraulic system to generate physiological flow rate and pressure, and three types of embolus analogs (elastic, stiff, and fragment-prone) engineered to match mechanically and phenotypically the emboli causing LVO strokes. LVO cases were replicated in the anterior and posterior circulation, and thrombectomy was attempted using suction catheters and/or stent retrievers.RESULTSThe test bed allowed radiation-free visualization of thrombectomy for LVO stroke in real cerebrovascular anatomy and flow conditions by transmural visualization of the intraluminal elements and procedures. The authors were able to successfully replicate 105 LVO cases with 184 passes in 12 brains (51 LVO cases and 82 passes in the anterior circulation, and 54 LVO cases and 102 passes in the posterior circulation). Observed recanalization rates in this model were graded using a Recanalization in LVO (RELVO) scale analogous to other measures of recanalization outcomes in clinical use.CONCLUSIONSThe human brain platform introduced and validated here enables the analysis of artery-embolus-device interaction under physiological hemodynamic conditions within the unmodified complexity of the cerebral vasculature inside the human brain.


Author(s):  
Douglas Griffith ◽  
Frank L. Greitzer

The purpose of this article is to re-address the vision of human- computer symbiosis expressed by J. C. R. Licklider nearly a half century ago, when he wrote: “The hope is that in not too many years, human brains and computing machines will be coupled together very tightly, and that the resulting partnership will think as no human brain has ever thought and process data in a way not approached by the information- handling machines we know today” (Licklider, 1960). Unfortunately, little progress was made toward this vision over 4 decades following Licklider’s challenge, despite significant advancements in the fields of human factors and computer science. Licklider’s vision was largely forgotten. However, recent advances in information science and technology, psychology, and neuroscience have rekindled the potential of making the Licklider’s vision a reality. This article provides a historical context for and updates the vision, and it argues that such a vision is needed as a unifying framework for advancing IS&T.


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