Effect of Assisted Exercise on Musculoskeletal System and Growth in Preterm Infants

Abstract Background osteopenia of prematurity, also known as bone metabolic disorder, is one of the common diseases in very low birth weight (VLBW) prematurity. Aim of the Work the primary aim of this study was to assess whether physical activity programs in preterm infants improve bone mineralization as well as growth and reduce the risk of fractures. The secondary aim was to include other potential benefits in terms of length of hospital stay, weaning from mechanical ventilation, feeding tolerance and adverse events. Patients and Methods this study was conducted on 36 neonate, Preterm infants (gestational age <33 completed weeks), body size appropriate for gestational age according to the growth curve, Postnatal age of ≥ 1 week with medically stable condition and favorable evolution that is presenting no associated diseases besides prematurity, tolerating enteral feeds of preterm formula at or above 100 kcal/kg/d. Methods the studied neonates were randomized into the physical exercise (n = 18) and control (n = 18) groups. Randomization was made by birth order. The studied neonates were subjected to full history taking, complete clinical assessment together with complete blood picture, C-reactive protein, serum Ca, Serum phosphorous concentration, Serum magnesium concentration. Serum alkaline phosphatase concentration, Serum Alanine Aminotransferase (ALT), Urinary calcium/phosphorous ratio. Babies admitted to NICU bathed, placed in incubator, attached to monitor. Infants in treatment and control groups received well defined interventions for the exercise group, systematic physical activity programs consisting of range-of-motion exercises with gentle compression, extension and flexion of all joints of both bilateral upper extremities; including the shoulder, elbow, and wrist and lower extremities; including the hip, knee and ankle, with a total of 12 joints Each activity was about 10 min a day and was carried out 5 times per week for 4 weeks. This program was started after 1 week of birth. Physical activity continued until discharge from hospital. Results the study demonstrated non significant difference in weight at enrollment (p = 0.516) which was turned into significant difference at end of the study as being higher among exercise group (p < 0.001). In our study although there was increase in the length and head circumference (p < 0.001) in the 2 groups no significant difference detected comparing them together. The control group had significantly lower serum phosphorus (p < 0.001), higher urinary Ca/Po4 ratio (p < 0.035) and higher ALP (p < 0.005) compared to excerise group at the end of the exercising protocol. Conclusion our study has demonstrated that regular physical activity programs (range-of-motion exercises), after an initial period of stabilization, might provide a simple intervention for improving musculoskeletal system and skeletal growth in preterm infants. They may also promote general growth in preterm infants.

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Association Between Magnesium and Oxidative Stress in Patients with Obesity

Current Nutrition & Food Science ◽

10.2174/1573401315666190730123842 ◽

2020 ◽

Vol 16 (5) ◽

pp. 743-748

Author(s):

Ana R.S. de Oliveira ◽

Kyria J.C. Cruz ◽

Jennifer B.S. Morais ◽

Juliana S. Severo ◽

Jéssica B. Beserra ◽

...

Keyword(s):

Oxidative Stress ◽

Thiobarbituric Acid ◽

Magnesium Concentration ◽

Control Group ◽

Compensatory Mechanism ◽

Thiobarbituric Acid Reactive Substances ◽

Magnesium Intake ◽

Significant Difference ◽

Dietary Magnesium ◽

And Control

Background: The role of minerals in preventing the generation of oxidative stress in obese individuals has been evaluated. Magnesium is an antioxidant nutrient and a cofactor of enzymes involved in the cell membrane stabilization, attenuating the effects of oxidative stress. Objective: To evaluate the association between magnesium and concentrations of thiobarbituric acid reactive substances (TBARS) in patients with obesity and eutrophic women. Methods: A cross-sectional study was conducted with 73 women, divided into two groups: case group (patients with obesity, n=27) and control group (eutrophic women, n=46). Measurements of body mass index and waist circumference were performed. Dietary magnesium intake was assessed by the three-day food record using the NutWin software. Urinary magnesium concentration was measured by atomic absorption spectrophotometry method. Plasma concentrations of thiobarbituric acid reactive substances (TBARS) were also determined. Results: Mean values of dietary magnesium intake were 161.59 ± 60.04 and 158.73 ± 31.96 for patients with obesity and control group, respectively, with no significant difference between the groups studied (p >0.05). The value of urinary excretion of magnesium was lower than the reference values in both groups, with no significant difference between the groups studied (p >0.05). The plasma concentration of thiobarbituric acid reactive substances was significantly higher in patients with obesity compared to the control group (p <0.001). There was no correlation between levels of magnesium biomarkers and the concentration of TBARS (p >0.05). Conclusion: Patients with obesity showed a reduced dietary magnesium intake which seems to induce hypomagnesuria as a compensatory mechanism. The marker of oxidative stress evaluated in this study was not influenced by magnesium.

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Influence of Ear Protectors on the Sleep of Preterm Newborns: A Randomized Controlled Clinical Study

Clinical Nursing Research ◽

10.1177/1054773818806171 ◽

2018 ◽

Vol 29 (4) ◽

pp. 260-267

Author(s):

Mônica Hiromi Sato ◽

Mavilde da Luz Gonçalves Pedreira ◽

Ariane Ferreira Machado Avelar ◽

Miriam Harumi Tsunemi ◽

Kelly Cristina Sbampato Calado Orsi ◽

...

Keyword(s):

Preterm Infants ◽

Gestational Age ◽

Total Sleep Time ◽

Sleep Time ◽

Exclusion Criteria ◽

Randomized Controlled ◽

Significant Difference ◽

Controlled Clinical Study ◽

Preterm Newborns ◽

Current Weight

The purpose of this study was to compare the effect of ear protectors on the sleep of preterm newborns during the “quiet” times in intermediate care nursery. This was a clinical, randomized, controlled crossover study conducted in two neonatal units in São Paulo, Brazil. The sample consisted of preterm infants who met the inclusion and exclusion criteria for the study. Polysomnography and unstructured observation were used for data collection. Twenty-four preterm infants with a mean gestational age of 33.2 weeks and current weight of 1.747 g were analyzed. There was no significant difference in the total sleep time of preterm infants with and without the use of ear protectors. Newborns with lower gestational age showed a significant reduction in total sleep time with the use of ear protectors ( p < .05). The use of ear protection did not increase the total sleep time for preterm infants.

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Environment, Genes, and Alcohol

PEDIATRICS ◽

10.1542/peds.71.6.989a ◽

1983 ◽

Vol 71 (6) ◽

pp. 989-990

Author(s):

NANCY L. GOLDEN

Keyword(s):

Socioeconomic Status ◽

Low Socioeconomic Status ◽

Gestational Age ◽

Control Groups ◽

Low Socioeconomic ◽

Significant Difference ◽

Infant Outcome ◽

Gestational Age At Birth ◽

And Control ◽

Age At Birth

In Reply.— Casey's point is well taken. An association between socioeconomic status and infant outcome has been documented. Our study and control groups were not matched on that factor, but on age, race, and gestational age at birth. A retrospective analysis of the socioeconomic status of study and control mothers indicates that they are all of low socioeconomic status (Hollingshead groups 4 and 5) and that there is no significant difference between the study and control groups.

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Investigating the Effect of Positive, Intermediate and Negative Enabling and Training Factors Affecting Physical Activity in Pregnant Women

10.21203/rs.3.rs-151184/v1 ◽

2021 ◽

Author(s):

Leila Kianfard ◽

Farkhonde Amin SHokravi ◽

Sakineh Rakhshanderou ◽

Shamsaddin Niknami

Keyword(s):

Physical Activity ◽

Pregnant Women ◽

Control Group ◽

Control Groups ◽

Enabling Factors ◽

Factors Affecting ◽

Significant Difference ◽

E Learning ◽

And Control ◽

Experimental Group

Abstract BackgroundPhysical activity during pregnancy period is one of the issues with priority during pregnancy period. Researches show that women reduce their physical activity during this period and are unaware of the benefits on the health of the mother and embryology. Although researchers regarding physical activity during pregnancy have prepared many guidelines; it is not however clear why pregnant women do not perform physical activity and the effectiveness factors that facilitate the desired behavior. MethodsThe research population included all pregnant women aged 18 to 40 years with gestational age of 12-38 weeks referring to the healthcare centers in District 5 of Tehran Municipality, from 22 districts of the city who had eliminated their physical activity during pregnancy. Questionnaires of physical activity assessment questionnaire after educational intervention in pregnant women (PPAQ) and a questionnaire designed based on the results of the needs assessment and the dimensions of the PEN-3 model were used for assessment. This study is a Research Clinical Trial (RCT). Due to the nature, a quasi-experimental research design (pre-test, post-test) with the control group was used in this research. ResultsBased on the obtained results, the intervention based on E-learning has a significant effect of enabling factors to increase physical activity in pregnant women in the experimental group. In addition, the intervention based on E-learning has a significant effect on the training factors in order to increase physical activity in pregnant women in the experimental group. ConclusionBased on the research results, it can be said that there is a statistically significant difference between the experimental and control groups in the scores obtained from training factors in the pretest and the experimental group. Furthermore, it can be said that there is a statistically significant difference between the experimental and control groups in the scores obtained from the enabling factors in the pre-test and the experimental group.

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Effect of neck range of motion exercises on neck disability and pain among patients undergoing thyroidectomy

Clinical Nursing Studies ◽

10.5430/cns.v8n4p1 ◽

2020 ◽

Vol 8 (4) ◽

pp. 1

Author(s):

Om Elhana Kamel Abo Shehata ◽

Omima Said M.H. Shehata ◽

Seham Mohamed Abd elalem

Keyword(s):

Neck Pain ◽

Range Of Motion ◽

Neck Disability Index ◽

Pain Scale ◽

Control Group ◽

Surgical Performance ◽

Surgical Department ◽

Significant Difference ◽

Neck Disability ◽

And Control

Objective: Thyroidectomy is a surgery in which head and neck became extended during operation to facilitate surgical performance. Patients experience neck pain and limitation to the range of motion following surgery. The study’s aim was to assess the effect of neck range of motion exercises on neck disability and pain among patients undergoing thyroidectomy.Methods: A quasi-experimental research design was utilized, the research was carried out at the surgical department in Shebin Emergency Hospital, at Shebin El-Kom District, Menoufia Governorate, Egypt. Sample; 90 adult subjects undergoing thyroidectomy and are welcoming to participate in the current research. Four Instruments for data collection: Instrument (1): Interview questionnaire sheet consists of two parts to assess subjects’ socio-demographic and medical data. Instrument (2): Visual analog pain scale to rate the patients’ level of pain intensity. Instrument (3): Neck disability index to assess neck pain and its effect on patients’ ability to perform daily activities. Instrument (4): Compliance assessment sheet to follow the patient’s adherence with neck range of motion exercise.Results: There was no statistically significant difference found between study and control group socio-demographic characteristics and medical history while there was a statistically significant difference between study and control group concerning neck disability and pain after one week and four weeks post-operative thyroidectomy.Conclusions: Patient compliance with a range of motion exercises significantly improves neck movement in order to be able to carry out daily life activities and reducing pain for the study group in comparison with the control group.Recommendation: Nurses who work in the general surgery department should include a neck range of motion exercises in providing the care and follow up protocol for the patients undergoing thyroidectomy.

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Placental Vascular Obstructive Lesions: Risk Factor for Developing Necrotizing Enterocolitis

Pathology Research International ◽

10.4061/2010/838917 ◽

2010 ◽

Vol 2010 ◽

pp. 1-7 ◽

Cited By ~ 3

Author(s):

Laure Dix ◽

Matthias Roth-Kleiner ◽

Maria-Chiara Osterheld

Keyword(s):

Risk Factor ◽

Preterm Infants ◽

Necrotizing Enterocolitis ◽

Premature Infants ◽

Strong Association ◽

Age Groups ◽

Control Group ◽

Age Group ◽

Significant Difference ◽

And Control

Necrotizing enterocolitis (NEC) is a severe neonatal disease affecting particularly preterm infants. Its exact pathogenesis still remains unknown. In this study, we have compared the prevalence of vascular obstructive lesions in placentae of premature newborns which developed NEC and of a control group. We further compared separately the findings of placentae of infants of less than 30 weeks of gestation, the age group in which NEC occurs most frequently. We found signs of fetal vascular obstructive lesions in 65% of the placentae of preterm patients developing NEC, compared to only 17% of the placentae of preterm patients in the control group. In the age groups below 30 weeks of gestation, 58.5% of placentae of later NEC patients presented such lesions compared to 24.5% in the control group. The significant difference between NEC and control group suggests a strong association between fetal vascular obstructive lesions and NEC. Therefore, we propose that fetal vascular obstructive lesions might be considered as a risk factor for the development of NEC in premature infants.

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A Comparative Study of Relationship between Micronutrients and Gestational Diabetes

ISRN Obstetrics and Gynecology ◽

10.5402/2012/470419 ◽

2012 ◽

Vol 2012 ◽

pp. 1-4 ◽

Cited By ~ 14

Author(s):

Farideh Akhlaghi ◽

Seyyed Majid Bagheri ◽

Omid Rajabi

Keyword(s):

Gestational Diabetes ◽

Pregnant Women ◽

Gestational Age ◽

Control Group ◽

Study Group ◽

Inclusion Criteria ◽

Control Groups ◽

Significant Difference ◽

Micronutrient Concentration ◽

And Control

In this paper, we studied the relation between the micronutrient and gestational diabetes. Therefore, we measured micronutrient concentration including Ni, Al, Cr, Mg, Fe, Zn, Cu, and Se in serum of women with gestational diabetes between 24 and 28 weeks of gestational age (study group) who had inclusion criteria and comparison with micronutrient levels in normal pregnant women with same gestational age (control group). Results showed that there was no significant difference between the serum micronutrient level (Ni, Al, Cr, Mg, Zn, Cu, Se) in study and control groups except serum level of iron which in serum of gestational diabetic women was lower than normal pregnant women and difference was significant.

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Incidence of Asymptomatic, Nontraumatic Unilateral Knee Hyperextension in the High School Athlete

Journal of Sport Rehabilitation ◽

10.1123/jsr.5.4.287 ◽

1996 ◽

Vol 5 (4) ◽

pp. 287-292

Author(s):

George A. Arangio ◽

Marie St. Amour-Myers ◽

James Reed

Keyword(s):

High School ◽

Range Of Motion ◽

Peak Torque ◽

Left Knee ◽

Control Group ◽

Control Groups ◽

Anterior Translation ◽

Significant Difference ◽

Posterior Translation ◽

And Control

Four hundred sixty-seven high school athletes were screened in apreparticipation athletic physical. Forty-six (9.8%) of these athletes presented with asymptomatic, nontraumatic unilateral hyperextension. Twenty-three athletes were reexamined and compared to a normal control group. A 2.5-cm, statistically significant heel-to-heel difference was recorded in the hyperextension group. Between the involved hyperextended and uninvolved legs, there were differences in average range of motion (132.04° vs. 130.74°, respectively), average manual anterior translation by KT-1000 (5.39 mm vs. 5.15 mm, respectively), average posterior translation (2.07 mm vs. 2.00 mm, respectively), average peak quadriceps torque (86.25 ft-lb vs. 84.06 ft-lb, respectively), and hamstring average peak torque (53.89 ft-lb vs. 52.93 ft-lb, respectively), though these differences were not statistically significant. In the control group, there was no heel-to-heel difference in the right versus the left knee. Heel-to-heel difference between the experimental and control groups was statistically significant. There was no statistically significant difference between range of motion, anterior translation, or posterior translation between the experimental and control groups.

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Make a Move Intervention to Reduce Childhood Obesity

The Journal of School Nursing ◽

10.1177/1059840516665217 ◽

2016 ◽

Vol 33 (3) ◽

pp. 205-213 ◽

Cited By ~ 6

Author(s):

Kimberly Nerud ◽

Haifa (Abou). Samra

Keyword(s):

Physical Activity ◽

Head Start ◽

Healthy Eating ◽

Social Cognitive ◽

Cognitive Theory ◽

Controlled Trial ◽

Significant Difference ◽

And Behavior ◽

And Control ◽

Relationship Of

Guided by the social cognitive theory, this randomized controlled trial tested the “Make a Move,” a provider-led intervention for Head Start parents aimed to produce changes in the outcomes of knowledge, attitude, and behavior of physical activity and healthy eating. Participants were parents of children ages 3–5 years enrolled in a Head Start program. Participants completed a 57-item questionnaire at baseline and postintervention. The Wilcoxon rank-sum test revealed a statistically significant difference between the intervention and control groups in scores on knowledge of healthy eating ( z = 1.99, p = .05), attitude of physical activity ( z = 2.71, p < .01), and behavior of physical activity ( z = 2.03, p = .04). Ten participants (77%) completed all four intervention sessions. This study provided new insights into the relationship of a provider-led intervention with respect to knowledge, attitude, and behaviors in healthy eating and physical activity.

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Time to regain birth weight - a marker to predict the severity of retinopathy of prematurity?

BMC Pediatrics ◽

10.1186/s12887-021-03027-x ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Ajay Anvekar ◽

Sam Athikarisamy ◽

Shripada Rao ◽

Andy Gill ◽

Elizabeth Nathan ◽

...

Keyword(s):

Preterm Infants ◽

Gestational Age ◽

Retinopathy Of Prematurity ◽

Oxygen Therapy ◽

Control Groups ◽

Gestational Age At Birth ◽

And Control ◽

Type 1 Rop ◽

Age At Birth

Abstract Background Poor weight gain in the first few weeks of life has been studied as a predictor of retinopathy of prematurity (ROP). Our aim was to assess whether time taken to regain birthweight (BW) be used as an additional marker to identify infants with type 1 ROP. Methods In this retrospective study, preterm infants (< 27 weeks gestational age at birth) born during the period from 1/1/2010–31/12/2015 at a tertiary neonatal intensive care unit in Australia were included. Twenty-seven preterm infants with Type 1 ROP were identified. Controls (No ROP or ROP other than type 1) were matched with cases on gestational age at birth and BW (1:4 ratio). Data were collected from the database and medical records. Results The median (IQR) gestational age for Type 1 ROP and control groups were 24 (24–26) and 25 (24–26) weeks respectively and median (IQR) BW for Type 1 ROP and control groups were 675 (635–810) and 773 (666–884) grams respectively. Preterm infants with Type 1 ROP were more likely to be small for gestational age (SGA) (18.5% vs 3.7%, p = 0.015) and had increased weeks on oxygen therapy (median 11.9 vs 9.1, p = 0.028). Time to regain BW was longer in preterm infants with type 1 ROP than controls but did not reach statistical significance (median 9 vs 7 days, OR 1.08, 95% CI 1.00–1.17, p = 0.059) adjusted for SGA and duration of oxygen therapy. The area under the curve from the time to regain BW model with adjustment for SGA and duration of oxygen therapy was 0.73 (95% CI 0.62–0.83). Conclusion We hypothesize that time to regain BW has potential to aid prediction of Type 1 ROP and this warrants further investigation in a larger prospective study.

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