Green tea and cardiovascular disease: from molecular targets towards human health

2008 ◽  
Vol 11 (6) ◽  
pp. 758-765 ◽  
Author(s):  
Nicoline Jochmann ◽  
Gert Baumann ◽  
Verena Stangl
2003 ◽  
Vol 83 (4) ◽  
pp. 951-953 ◽  
Author(s):  
W. L Allan ◽  
C. Peiris ◽  
A. W. Bown ◽  
B. J. Shelp

Gamma-hydroxybutyrate (GHB) is an illicit drug, which may be derived in plants from a stress-inducible metabolite known as gamma-aminobutyrate. Here, oxygen deficiency caused the accumulation of GHB in green tea and soybean sprouts (76 and 155 nmol g-1 fresh weight, respectively). These findings demonstrate that GHB levels are elevated in severely modified atmospheres, but they pose no risk to human health. Further work is required to assess the extent of this phenomenon. Key words: Gamma-hydroxybutyrate, gamma-aminobutyrate, oxygen deficiency, tea, bean sprouts


Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Masayuki Teramoto ◽  
Isao Muraki ◽  
Kokoro Shirai ◽  
Akiko Tamakoshi ◽  
Hiroyasu Iso

Background: Both green tea and coffee consumption have been associated with lower risks of mortality from cardiovascular disease (CVD) and all causes in general population, but little is known about those impact on persons with history of CVD. We examined the association of those consumption with these mortalities among persons with and without history of stroke or myocardial infarction in general population. Methods: The study subjects were 60,664 participants (896 stroke and 1751 myocardial infarction survivors and 58,017 persons with no history of stroke or myocardial infarction), aged 40-79 years at the baseline (1988-1990), who completed a lifestyle and medical history questionnaire including self-administered food frequency under the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study). Results: During the median follow-up of 18.5 years, a total of 12,745 (7,458 men and 5,287 women) deaths including 3,737 CVD deaths were documented. Green tea and coffee consumption were inversely associated with CVD and all-cause mortality among myocardial infarction survivors as well as persons without history of stroke or myocardial infarction. After adjustment for known cardiovascular risk factors, the lower risks of mortality from CVD and all-causes associated with frequent green tea consumption (5-6 and ≥7 cups/day) or coffee consumption (≥2 cups/day) remained statistical. Conclusions: Both green tea and coffee consumption were inversely associated with risks of CVD and all-cause mortality among myocardial infarction survivors and persons without history of stroke or myocardial infarction.


2008 ◽  
Vol 78 (6) ◽  
pp. 275-281 ◽  
Author(s):  
Niels Boon

Obesity is a major health problem in the developed and developing world. Many “functional” foods and ingredients are advocated for their effects on body composition but few have consistent scientific support for their efficacy. However, an increasing amount of mechanistic and clinical evidence is building for green tea. The tea plant is naturally rich in a group of antioxidants known as catechins. Unlike black tea, green tea production involves little processing and fermentation and therefore, green tea brews are rich in catechins. Green tea has been suggested to have a number of potential health benefits in areas such as cardiovascular disease, cancer prevention, glucose homeostasis and dental health. Although there is some promising evidence in all of these areas, more data from human intervention trials are needed. A lot of attention has lately been focused on the beneficial effects of green tea on body composition and particularly visceral fat, which has been shown to have a strong link with different components of the metabolic syndrome such as cardiovascular disease and type 2 diabetes. Most, but not all, of the positive results come from a number Asian studies, in which overweight subjects (men and women) consumed green tea for approximately 12 weeks. Finally, green tea may also have measurable acute effects on energy metabolism and fat oxidation and in particular during physical activity, as evidenced by other studies specifically looking at these endpoints. Small cumulative effects on energy metabolism could also be responsible for the longer-tem effects of green tea on body composition, and these long-term effects may also be most apparent in the context of moderate physical activity. However, more research is needed to further clarify the exact mechanisms of action and to extrapolate these findings to non-Asian populations.


2016 ◽  
Vol 31 (9) ◽  
pp. 853-865 ◽  
Author(s):  
Junxiu Liu ◽  
Shiwei Liu ◽  
Haiming Zhou ◽  
Timothy Hanson ◽  
Ling Yang ◽  
...  

MedChemComm ◽  
2019 ◽  
Vol 10 (12) ◽  
pp. 2024-2037 ◽  
Author(s):  
Geetha B. Kumar ◽  
Bipin G. Nair ◽  
J. Jefferson P. Perry ◽  
David B. C. Martin

Members of the matrix metalloproteinase (MMP) family have biological functions that are central to human health and disease, and MMP inhibitors have been investigated for the treatment of cardiovascular disease, cancer and neurodegenerative disorders.


Science ◽  
2018 ◽  
Vol 362 (6416) ◽  
pp. 776-780 ◽  
Author(s):  
Christopher L. Gentile ◽  
Tiffany L. Weir

Diet affects multiple facets of human health and is inextricably linked to chronic metabolic conditions such as obesity, type 2 diabetes, and cardiovascular disease. Dietary nutrients are essential not only for human health but also for the health and survival of the trillions of microbes that reside within the human intestines. Diet is a key component of the relationship between humans and their microbial residents; gut microbes use ingested nutrients for fundamental biological processes, and the metabolic outputs of those processes may have important impacts on human physiology. Studies in humans and animal models are beginning to unravel the underpinnings of this relationship, and increasing evidence suggests that it may underlie some of the broader effects of diet on human health and disease.


Author(s):  
Tabinda Sattar

: Herbal Teas prepared from leaves, roots, fruits and flowers of different herbs contain many useful nutrients that may be a good replacement for medicating of certain specific diseases. These herbal teas are very rich in poly-phenols so these are very much significant for their antioxidant, anti-inflammation, anticancer, anticardiovascular, antimicrobial, antihyperglycemic, and antiobesity properties. Medical chronic conditions such as cardiovascular disease, cancer, Alzheimer’s disease, Parkinson’s disease, constipation, diabetes and bed wetting in children can be easily cured by the use of these herbal teas in regular and moderate amounts. This Review focuses on the diverse constituents of herbal tea due to which it can be an attractive alternative toward promoting human health.


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