scholarly journals Cerebral Hemodynamic Changes during the Trigeminocardiac Reflex: Description of a New Animal Model Protocol

2010 ◽  
Vol 10 ◽  
pp. 1416-1423 ◽  
Author(s):  
N. Sandu ◽  
J. Cornelius ◽  
A. Filis ◽  
C. Nöthen ◽  
J. Rasper ◽  
...  
Keyword(s):  
Animal Model ◽  
Senior Author ◽  
Hemodynamic Changes ◽  
Cerebral Hemodynamic ◽  
Trigeminocardiac Reflex ◽  
Brainstem Reflex ◽  
Peripheral Stimulation ◽  
Current State ◽  
First Time ◽  
Central Stimulation

The trigeminocardiac reflex (TCR) is a well-known brainstem reflex, first described in skull base and neurosurgery by the senior author in 1999, leading to reflex apnea, bradycardia, and changes of mean arterial pressure. There seem to be differences between peripheral and central stimulation of the TCR, and there is a lack of clear data about the cerebral hemodynamic changes during the TCR. However, the research of this reflex principally focused on clinical cases for peripheral and central stimulation during the last years, and on rabbits for peripheral stimulation several decades ago, so there was a need for an animal model that allows us to use the current state-of-the-art imaging methods. The new animal model protocol as introduced by the authors gives, for the first time, deep insights into the cerebral hemodynamic changes during the TCR and gives substantial evidence whether the TCR represents an oxygen-conserving reflex or not.

Disability as a social phenomenon

2020 ◽  
pp. 22-38
Author(s):  
Natalia Guseva ◽  
Vitaliy Berdutin
Keyword(s):  
Social Protection ◽  
Russian Society ◽  
Stage Model ◽  
High Quality ◽  
Rehabilitation Programs ◽  
Current State ◽  
The Social ◽  
Consistent Solution ◽  
First Time

At present, the problem of establishing disability is a point at issue in Russia. Despite the fact that medical criteria for disability are being developed very actively, high-quality methods for assessing social hallmarks are still lacking. Since disability is a phenomenon inherent in any society, each state forms a social and economic policy for people with disabilities in accordance with its level of development, priorities and opportunities. We have proposed a three-stage model, which includes a system for the consistent solution of the main tasks aimed at studying the causes and consequences of the problems encountered today in the social protection of citizens with health problems. The article shows why the existing approaches to the determination of disability and rehabilitation programs do not correspond to the current state of Russian society and why a decrease in the rate of persons recognized as disabled for the first time does not indicate an improvement in the health of the population. The authors proposed a number of measures with a view to correcting the situation according to the results of the study.

scholarly journals Electro-Quasistatic Animal Body Communication for Untethered Rodent Biopotential Recording

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Shreeya Sriram ◽  
Shitij Avlani ◽  
Matthew P. Ward ◽  
Shreyas Sen
Keyword(s):  
Lower Energy ◽  
Sensor Node ◽  
State Of The Art ◽  
The Body ◽  
Animal Body ◽  
Current State ◽  
Communication Modalities ◽  
First Time ◽  
Biopotential Recording

AbstractContinuous multi-channel monitoring of biopotential signals is vital in understanding the body as a whole, facilitating accurate models and predictions in neural research. The current state of the art in wireless technologies for untethered biopotential recordings rely on radiative electromagnetic (EM) fields. In such transmissions, only a small fraction of this energy is received since the EM fields are widely radiated resulting in lossy inefficient systems. Using the body as a communication medium (similar to a ’wire’) allows for the containment of the energy within the body, yielding order(s) of magnitude lower energy than radiative EM communication. In this work, we introduce Animal Body Communication (ABC), which utilizes the concept of using the body as a medium into the domain of untethered animal biopotential recording. This work, for the first time, develops the theory and models for animal body communication circuitry and channel loss. Using this theoretical model, a sub-inch$$^3$$ 3 [1″ × 1″ × 0.4″], custom-designed sensor node is built using off the shelf components which is capable of sensing and transmitting biopotential signals, through the body of the rat at significantly lower powers compared to traditional wireless transmissions. In-vivo experimental analysis proves that ABC successfully transmits acquired electrocardiogram (EKG) signals through the body with correlation $$>99\%$$ > 99 % when compared to traditional wireless communication modalities, with a 50$$\times$$ × reduction in power consumption.

scholarly journals Cerebral Hemodynamic Changes Induced by a Lumbar Puncture in Good-Grade Subarachnoid Hemorrhage

2012 ◽  
Vol 2 (1) ◽  
pp. 52-62 ◽  
Author(s):  
Eric A. Schmidt ◽  
Stein Silva ◽  
Jean François Albucher ◽  
Aymeric Luzi ◽  
Isabelle Loubinoux ◽  
...  
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Lumbar Puncture ◽  
Hemodynamic Changes ◽  
Cerebral Hemodynamic ◽  
Good Grade

scholarly journals The assessment of woody plants vital state in the landscaping of Ishim

2020 ◽  
Vol 9 (3) ◽  
pp. 142-147
Author(s):  
Olga E. Tokar
Keyword(s):  
Woody Plants ◽  
Current State ◽  
Quantitative Characteristics ◽  
Vital State ◽  
Total Composition ◽  
Vitality Index ◽  
First Time ◽  
The Town ◽  
Trees And Shrubs ◽  
Qualitative And Quantitative Characteristics

This paper analyzes the current state of landscaping in Ishim. The data on the qualitative and quantitative characteristics of woody plants have been obtained for the first time; the assessment of trees and shrubs state is based on the analysis of the vitality index. A database of green plants within 21 objects in Ishim was created and analyzed. The paper also contains data on the species diversity of trees and shrubs in Ishim. It turned out that the objects under study have trees and shrubs placed in special dividing strips, linearly, in rows or in small compact groups, less often they are planted singly. The species composition is represented by 47 species from 28 genera, 16 families and 2 divisions. The biomorphological structure is represented by trees (25, or 53% of species) and shrubs (22, or 47% of species). The total composition of tree and shrub plantations, determined by the number of trunks (bushes) and the percentage of woody plants, is 2854; the composition of the preserved ones is 2 815 (99%) pieces; the ones assigned for removal are 39 (1%) pcs. The vitality index shows that among 85% of the studied objects of the town at the time of the survey were healthy, among 10% of the objects they were qualified as damaged, among 5% of them were severely damaged. Based on the results of examining crowns and trunks of woody plants, signs of diseases and pests, a plan of measures for the treatment, restoration and preservation of woody plants was drawn up and recommendations were given for caring, sanitary felling and removal of single specimens.

scholarly journals ASSESSMENT OF THE CURRENT STATE OF COASTAL WATERS OF THE SOUTHERN PART OF LAKE BAIKAL ON SANITARY AND MICROBIOLOGICAL INDICATORS WITH USE OF THE TEST SYSTEMS

2018 ◽  
pp. 54-58
Author(s):  
I.V. Mosharova ◽  
V.V. Il’inskij ◽  
O.V. Il’ina
Keyword(s):  
Lake Baikal ◽  
Coastal Waters ◽  
Test Systems ◽  
Current State ◽  
Wide Range ◽  
Microbial Number ◽  
Southern Site ◽  
First Time ◽  
Number Of Bacteria ◽  
Microbiological Indicators

Sanitary and microbiological researches of a coastal surface water of the southern part of Lake Baikal (from the Listvyanka to the Tanghui) were conducted in June, 2017. Total number of bacteria varied over a wide range – from 0.93 million сells/ml up to 2:05 million сells/ml, with an average 1.41 ± 0.3 million сells/ml. Biomass of bacteria varied from 11.05 to 305.00 mg С/m3, with an average of 123.34 mg С/m3. Coastal waters of the southern site of Lake Baikal mainly had a beta-meso-saprobic status in June, 2017. The total microbial number was determined with the use of the test systems for the first time. The values of the total microbial number were less than 1 000 COU/ml and varied from 9 to 412 COU/ml. Innovative test systems Petrifilm are of great interest for rapid assessments of the sanitary and microbiological status of reservoirs directly in the field conditions.

A New Formulation for the Dial-a-Ride Problem

2021 ◽  
Author(s):  
Yannik Rist ◽  
Michael A. Forbes
Keyword(s):  
Time Window ◽  
Valid Inequalities ◽  
Route Planning ◽  
Branch And Cut ◽  
Mixed Integer ◽  
Planning Problem ◽  
Current State ◽  
New Formulation ◽  
First Time ◽  
Delivery Location

This paper proposes a new mixed integer programming formulation and branch and cut (BC) algorithm to solve the dial-a-ride problem (DARP). The DARP is a route-planning problem where several vehicles must serve a set of customers, each of which has a pickup and delivery location, and includes time window and ride time constraints. We develop “restricted fragments,” which are select segments of routes that can represent any DARP route. We show how to enumerate these restricted fragments and prove results on domination between them. The formulation we propose is solved with a BC algorithm, which includes new valid inequalities specific to our restricted fragment formulation. The algorithm is benchmarked on existing and new instances, solving nine existing instances to optimality for the first time. In comparison with current state-of-the-art methods, run times are reduced between one and two orders of magnitude on large instances.

HISTORICALLY FORMED STRUCTURE OF THE GARDENING SYSTEM INTHE CENTER OF YEREVAN AND ITS MODERN PROBLEMS

2020 ◽  
pp. 5-19
Author(s):  
V.S. Teodoronsky ◽  
◽  
V.A. Leonova ◽  
K.K. Vardanyan ◽  
◽  
...  
Keyword(s):  
Urban Planning ◽  
Soviet Period ◽  
Design Solution ◽  
Tree Plantations ◽  
Existing Problems ◽  
General Plan ◽  
Current State ◽  
First Time ◽  
The City ◽  
Formed Structure

The article examines the historical, landscape and urban planning features of Yerevan, which determined the planning structure and development of the city's greening system. The analysis of the city relief in terms of heights and natural types of landscapes is given. Particular attention is paid to the description of urban planning axes and compositional nodes of the landscaping system, created during the Soviet period according to the general plan of 1937.For the first time, the structure and types of tree plantations of squares and city streets are analyzed, depending on their functional purpose and location in the city. The description of the design solution for the Children’s railway in the gorge of Hrazdan river and the station building, as well as the widespread assortment of the trees and bushes in the city in the Soviet period. The main problems of the current state of the green areas of the center are considered and the directions of reorganization of the city greening system are given. The ways of solving existing problems by the introducing regulations for the preservation of existing plantings in center of Yerevan and the prospects for their development are proposed.

Blend the Lab Course, Flip the Responsibility

2015 ◽  
pp. 1483-1505
Author(s):  
Mark A. Gallo
Keyword(s):  
Technical Problems ◽  
Student Responsibility ◽  
Class Time ◽  
Current State ◽  
Real Value ◽  
Upper Level ◽  
Intensive Course ◽  
First Time ◽  
Blended Course

An upper-level special topics course in Applied, Environmental, and Medical Microbiology was offered for the first time. It was decided by the author to offer it as a blended course. There were some compelling reasons to do so: first and foremost, it allowed class time to be spent doing what one should in a lab-intensive course: remark on current state of knowledge and literature, describe experimental design, discuss potential outcomes, troubleshoot technical problems as they arise, and offer suggestions regarding students' research throughout the process. The ultimate goal and real value of the blended classroom in this instance was elevating the level of student responsibility and forcing them to view a science class as something more than a collection of facts: rather as a very active class, one that requires individual action. It was also designed to allow the students to participate in fundamental scientific research with the help of a mentor in a manner that was/is still practiced and in full view of peer review. The role of the faculty member changes to one of providing guidance instead of content in the classroom, and so it gives one more individual time with the students; this time can be used for diagnostic, formative, and summative assessment.

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