Blend the Lab Course, Flip the Responsibility

2015 ◽  
pp. 1483-1505
Author(s):  
Mark A. Gallo

An upper-level special topics course in Applied, Environmental, and Medical Microbiology was offered for the first time. It was decided by the author to offer it as a blended course. There were some compelling reasons to do so: first and foremost, it allowed class time to be spent doing what one should in a lab-intensive course: remark on current state of knowledge and literature, describe experimental design, discuss potential outcomes, troubleshoot technical problems as they arise, and offer suggestions regarding students' research throughout the process. The ultimate goal and real value of the blended classroom in this instance was elevating the level of student responsibility and forcing them to view a science class as something more than a collection of facts: rather as a very active class, one that requires individual action. It was also designed to allow the students to participate in fundamental scientific research with the help of a mentor in a manner that was/is still practiced and in full view of peer review. The role of the faculty member changes to one of providing guidance instead of content in the classroom, and so it gives one more individual time with the students; this time can be used for diagnostic, formative, and summative assessment.

Author(s):  
Mark A. Gallo

An upper-level special topics course in Applied, Environmental, and Medical Microbiology was offered for the first time. It was decided by the author to offer it as a blended course. There were some compelling reasons to do so: first and foremost, it allowed class time to be spent doing what one should in a lab-intensive course: remark on current state of knowledge and literature, describe experimental design, discuss potential outcomes, troubleshoot technical problems as they arise, and offer suggestions regarding students’ research throughout the process. The ultimate goal and real value of the blended classroom in this instance was elevating the level of student responsibility and forcing them to view a science class as something more than a collection of facts: rather as a very active class, one that requires individual action. It was also designed to allow the students to participate in fundamental scientific research with the help of a mentor in a manner that was/is still practiced and in full view of peer review. The role of the faculty member changes to one of providing guidance instead of content in the classroom, and so it gives one more individual time with the students; this time can be used for diagnostic, formative, and summative assessment.


2020 ◽  
Vol 74 ◽  
pp. 498-503
Author(s):  
Grzegorz K. Jakubiak ◽  
Józefina Ochab-Jakubiak ◽  
Grzegorz Cieślar ◽  
Agata Stanek

COVID-19 is an infectious disease caused by novel coronavirus SARS-CoV-2, a betacoronavirus comprised of single-stranded ribonucleic acid (RNA), the first time reported in December 2019 as pneumonia with unknown etiology in Wuhan City in China. It is a very important current problem for public health worldwide. A typical clinical course includes dyspnoea, dry cough and fever. In the presented paper we conducted the literature review and described the most important facts within the current state of knowledge about symptomatology and pathophysiology of gastrointestinal dysfunction in the course of COVID-19. Data about prevalence of gastrointestinal symptoms in the course of COVID-19 show wide divergence in the cited literature. Generally, the most common reported digestive symptoms were loss of appetite, nausea and vomiting. Liver injury in the course of COVID-19 is also an important and not well understood problem. The virus has high affinity to cells containing angiotensin- -converting enzyme 2 (ACE2) protein. Digestive symptoms of COVID-19 may be associated with ACE2 expression in epithelial cells in upper oesophagus, ileum and colon. Previous scientific reports have elucidated the role of ACE2 in modulating intestinal inflammation and diarrhoea.


2019 ◽  
Vol 39 (5) ◽  
Author(s):  
Callum J. O’Kane ◽  
Edel M. Hyland

Abstract Saccharomyces cerevisiae (budding yeast) and Schizosaccharomyces pombe (fission yeast) are two of the most recognised and well-studied model systems for epigenetic regulation and the inheritance of chromatin states. Their silent loci serve as a proxy for heterochromatic chromatin in higher eukaryotes, and as such both species have provided a wealth of information on the mechanisms behind the establishment and maintenance of epigenetic states, not only in yeast, but in higher eukaryotes. This review focuses specifically on the role of histone modifications in governing telomeric silencing in S. cerevisiae and centromeric silencing in S. pombe as examples of genetic loci that exemplify epigenetic inheritance. We discuss the recent advancements that for the first time provide a mechanistic understanding of how heterochromatin, dictated by histone modifications specifically, is preserved during S-phase. We also discuss the current state of our understanding of yeast nucleosome dynamics during DNA replication, an essential component in delineating the contribution of histone modifications to epigenetic inheritance.


2019 ◽  
Vol 7 (5) ◽  
pp. 474-480
Author(s):  
Serik Erzhanovich Abishev ◽  
Ainur Sauletzhanovna Taldybayeva ◽  
Murat Kamashevich Bekkozhin ◽  
Serik Syzdykovich Rysbekov ◽  
Ualikhan Tulenovich Karymsakov

Purpose of the study: The purpose of the present article is to study, generalize and determine the main tendencies in the spatial organization of the urban cinema environment of Kazakhstani cities within post-Soviet cinematographic materials in the context of searching for an identity notion and a general “urban myth” concept. Methodology: The objects of the study include films of post-restructuring cinema production and the image of a big city depicted in them, different from the stereotype prevailing in Soviet cinema, which was analyzed in the paradigm of creating a cinema environment in Kazakhstani films during the period of independence. For the careful examination of cinematographic artistic means, the study used hermeneutical, functional and comparative methods. Main findings: The results showed that the article dealt with the environment-forming and image-forming role of cinema in architecture, as well as with the interaction factors of arts in artistic culture and the spatial organization of the urban environment. The development trends of cinema were considered as potential new vectors of the compositional components of the environment. Applications of this study: The study may be used for presenting a careful review of the current state of the problem of the spatial organization of the urban cinema environment as a search for identity in Kazakhstani post-Soviet cinematography, as well as for further investigations in similar directions. The article might be useful for students of art faculties of colleges and universities, specialists in cinematography and all those interested in the study area. Novelty/Originality of this study: The study of the urban cinema environment was firstly conducted using the paradigm of the identity search. Multiple methods were used in order to present a deep and thorough analysis of the spatial organization of the city environment in Kazakhstani post-Soviet films. The problem of urban environment creation has been analyzed using the mentioned criteria in synchronic and diachronic dimensions for the first time.


2006 ◽  
Vol 6 (4) ◽  
pp. 6933-6956 ◽  
Author(s):  
V. Sivakumar ◽  
H. Bencherif ◽  
A. Hauchecorne ◽  
P. Keckhut ◽  
D. N. Rao ◽  
...  

Abstract. Using four years of Rayleigh lidar data collected from three different northern hemisphere stations (Gadanki 13.5° N, 79.2° E ; Mt. Abu 24.5° N, 72.7° E and Observatoire de Haute Provence: OHP; 44° N, 6° E), the characteristics of double (separated) stratopause occurrence are presented here, for the first time. The characteristics are illustrated by a seasonal change during summer and winter and the variation in percentage of occurrence from place to place. It is found that the over-all mean normal stratopause (NS) positioned at the middle level of double stratopause (upper and lower level) with its location nearer to the lower level of double stratopause (LDS) than to the upper level of double stratopause (UDS). The frequency distribution of NS, LDS and UDS demonstrated variability with location, indicating role of dynamical activity. By making use of a quasi-continuous 40 days of lidar observations over Gadanki and OHP, the responsibility of Gravity Wave (GW) and Planetary Wave (PW) activity for the LDS and UDS occurrence are examined and presented.


Crisis ◽  
2016 ◽  
Vol 37 (2) ◽  
pp. 130-139 ◽  
Author(s):  
Danica W. Y. Liu ◽  
A. Kate Fairweather-Schmidt ◽  
Richard Burns ◽  
Rachel M. Roberts ◽  
Kaarin J. Anstey

Abstract. Background: Little is known about the role of resilience in the likelihood of suicidal ideation (SI) over time. Aims: We examined the association between resilience and SI in a young-adult cohort over 4 years. Our objectives were to determine whether resilience was associated with SI at follow-up or, conversely, whether SI was associated with lowered resilience at follow-up. Method: Participants were selected from the Personality and Total Health (PATH) Through Life Project from Canberra and Queanbeyan, Australia, aged 28–32 years at the first time point and 32–36 at the second. Multinomial, linear, and binary regression analyses explored the association between resilience and SI over two time points. Models were adjusted for suicidality risk factors. Results: While unadjusted analyses identified associations between resilience and SI, these effects were fully explained by the inclusion of other suicidality risk factors. Conclusion: Despite strong cross-sectional associations, resilience and SI appear to be unrelated in a longitudinal context, once risk/resilience factors are controlled for. As independent indicators of psychological well-being, suicidality and resilience are essential if current status is to be captured. However, the addition of other factors (e.g., support, mastery) makes this association tenuous. Consequently, resilience per se may not be protective of SI.


Author(s):  
Svitlana Ilkovych ◽  
◽  
Maryna Korol ◽  

The article considers the essence of blockchain technology and the possibility of its application in the banking sector. The current state of development and application of blockchain technologies in various industries is analyzed. The pros and cons of using blockchain technologies for the banking sector are identified. Emphasis is placed on the role of blockchain technologies in the further development of the banking sector. The most promising directions of development of this technology are considered. Particular attention is paid to examples of the use of blockchain technology by global banking institutions.


2018 ◽  
pp. 1060-1068
Author(s):  
Galina A. Dvoenosova ◽  

The article assesses synergetic theory of document as a new development in document science. In information society the social role of document grows, as information involves all members of society in the process of documentation. The transformation of document under the influence of modern information technologies increases its interest to representatives of different sciences. Interdisciplinary nature of document as an object of research leads to an ambiguous interpretation of its nature and social role. The article expresses and contends the author's views on this issue. In her opinion, social role of document is incidental to its being a main social tool regulating the life of civilized society. Thus, the study aims to create a scientific theory of document, explaining its nature and social role as a tool of social (goal-oriented) action and social self-organization. Substantiation of this idea is based on application of synergetics (i.e., universal theory of self-organization) to scientific study of document. In the synergetic paradigm, social and historical development is seen as the change of phases of chaos and order, and document is considered a main tool that regulates social relations. Unlike other theories of document, synergetic theory studies document not as a carrier and means of information transfer, but as a unique social phenomenon and universal social tool. For the first time, the study of document steps out of traditional frameworks of office, archive, and library. The document is placed on the scales with society as a global social system with its functional subsystems of politics, economy, culture, and personality. For the first time, the methods of social sciences and modern sociological theories are applied to scientific study of document. This methodology provided a basis for theoretical vindication of nature and social role of document as a tool of social (goal-oriented) action and social self-organization. The study frames a synergetic theory of document with methodological foundations and basic concepts, synergetic model of document, laws of development and effectiveness of document in the social continuum. At the present stage of development of science, it can be considered the highest form of theoretical knowledge of document and its scientific explanatory theory.


Author(s):  
I. V. Bukhtiyarov

The article presents the results of the analysis of health, working conditions and prevalence of adverse production factors, the structure of the detected occupational pathology in the working population of the Russian Federation. The article presents Statistical data on the dynamics of the share of workplaces of industrial enterprises that do not meet hygienic standards, occupational morbidity in 2015-2018 for the main groups of adverse factors of the production environment and the labor process. The indicators of occupational morbidity over the past 6 years in the context of the main types of economic activity, individual subjects of the Russian Federation, classes of working conditions, levels of specialized occupational health care. The role of the research Institute of occupational pathology and occupational pathology centers in solving organizational, methodological and practical tasks for the detection, treatment, rehabilitation and prevention of occupational diseases is shown. The basic directions of activity in the field of preservation and strengthening of health of workers, and also safety at a workplace are defined.


2020 ◽  
Author(s):  
Armand Chatard ◽  
Margaux Renoux ◽  
Jean Monéger ◽  
Leila Selimbegovic

Research indicates that individuals often deal with mortality salience by affirming beliefs in national or cultural superiority (worldview defense). Because worldview defense may be associated with negative consequences (discrimination), it is important to identify alternative means to deal with death-related thoughts. In line with an embodied terror management perspective, we evaluate for the first time the role of physical warmth in reducing defensive reaction to mortality salience. We predicted that, like social affiliation (social warmth), physical warmth could reduce worldview defense when mortality is salient. In this exploratory (preregistered) study, 202 French participants were primed with death-related thoughts, or an aversive control topic, in a heated room or a non-heated room. The main outcome was worldview defense (ethnocentric bias). We found no main effect of mortality salience on worldview defense. However, physical warmth reduced worldview defense when mortality was salient. Implications for an embodied terror management perspective are discussed.


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