scholarly journals Estimating the Effect and Cost-Effectiveness of Facemasks in Reducing the Spread of the Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) in Uganda

2020 ◽  
Author(s):  
Betty K Nannyonga ◽  
Rhoda K Wanyenze ◽  
Pontiano Kaleebu ◽  
John M Ssenkusu ◽  
Tom Lutalo ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Reproduction Number ◽  
Health Workers ◽  
Respiratory Infections ◽  
Cost Effective ◽  
Face Mask ◽  
Effective Protection ◽  
Per Capita ◽  
Provision Of Care ◽  
Effective Analysis

AbstractEvidence that face masks provide effective protection against respiratory infections in the community is scarce. However, face masks are widely used by health workers as part of droplet precautions when caring for patients with respiratory infections. It would therefore be reasonable to suggest that consistent widespread use of face masks in the community could prevent further spread of the Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2). In this study we examine public face mask wearing in Uganda where a proportion wears masks to protect against acquiring, and the other to prevent from transmitting SARS-CoV-2. The objective of this study was to determine what percentage of the population would have to wear face masks to reduce susceptibility to and infectivity of SARS-COV-2 in Uganda, keeping the basic reproduction number below unity and/or flattening the curve. We used an SEIAQRD model for the analysis. Results show that implementation of facemasks has a relatively large impact on the size of the coronavirus epidemic in Uganda. We find that the critical mask adherence is 5 per 100 when 80% wear face masks. A cost-effective analysis shows that utilizing funds to provide 1 public mask to the population has a per capita compounded cost of USD 1.34. If provision of face masks is done simultaneously with supportive care, the per capita compounded cost is USD 1.965, while for the case of only treatment and no provision of face masks costs each Ugandan USD 4.0579. We conclude that since it is hard to achieve a 100% adherence to face masks, government might consider provision of face masks in conjunction with provision of care.

scholarly journals SARS-CoV-2: how safe is it to fly and what can be done to enhance protection?

2020 ◽  
Author(s):  
Anthony D Harries ◽  
Leonardo Martinez ◽  
Jeremiah M Chakaya
Keyword(s):  
Risk Factors ◽  
Severe Acute Respiratory Syndrome ◽  
Respiratory Infections ◽  
Face Mask ◽  
Personal Protection ◽  
Sars Coronavirus ◽  
Published Evidence ◽  
The Face

Abstract With lockdown restrictions over coronavirus disease 2019 being relaxed, airlines are returning to the skies. Published evidence of severe acute respiratory syndrome (SARS) coronavirus 2 transmission on aircraft is limited, but in-flight transmission of respiratory infections such as tuberculosis, influenza and SARS has been well described. Risk factors include proximity to index patients and sitting in aisle seats. Personal protection on aircraft could be enhanced by always wearing a well-fitting face mask and face shield or sunglasses, wiping surfaces and hands with alcohol-based sanitizers, not touching the face, not queuing for washrooms, changing seats if nearby passengers are coughing and choosing a window rather than an aisle seat.

scholarly journals Cost-effectiveness analysis on measles transmission with vaccination and treatment intervention

2021 ◽  
Vol 6 (11) ◽  
pp. 12491-12527
Author(s):  
Shinta A. Rahmayani ◽  
◽  
Dipo Aldila ◽  
Bevina D. Handari
Keyword(s):  
Medical Treatment ◽  
Optimal Strategy ◽  
Deterministic Model ◽  
Reproduction Number ◽  
Equilibrium Points ◽  
Cost Effective ◽  
Qualitative Behaviour ◽  
Effectiveness Analysis ◽  
The Cost ◽  
Effective Analysis

<abstract><p>A deterministic model which describes measles' dynamic using newborns and adults first and second dose of vaccination and medical treatment is constructed in this paper. Mathematical analysis about existence of equilibrium points, basic reproduction number, and bifurcation analysis conducted to understand qualitative behaviour of the model. For numerical purposes, we estimated the parameters' values of the model using monthly measles data from Jakarta, Indonesia. Optimal control theory was applied to investigate the optimal strategy in handling measles spread. The results show that all controls succeeded in reducing the number of infected individuals. The cost-effective analysis was conducted to determine the best strategy to reduce number of infected individuals with the lowest cost of intervention. Our result indicates that the use of the first dose measles vaccine with medical treatment is the most optimal strategy to control measles transmission.</p></abstract>

scholarly journals Face Mask: A Novel Material for Protection against Bacteria/Virus

2021 ◽  
Author(s):  
Thilagavathi Govindharajan ◽  
Viju Subramoniapllai
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Avian Influenza ◽  
Health Workers ◽  
Face Mask ◽  
Test Methods ◽  
Recent Developments ◽  
Novel Material ◽  
The Individual ◽  
Environment Evolution ◽  
Viral Respiratory

Facemask is defined as a loose-fitting device which creates a physical barrier between the mouth and nose of the individual wearing mask and likely pollutants in the immediate environment. Evolution of severe viral respiratory infectious agents such as pandemic COVID-19, severe acute respiratory syndrome, pandemic influenza and avian influenza has driven the use of protective face masks by public and health workers. In this chapter, characteristics features and uses of different types of masks are discussed. Characteristics of various nonwoven technologies for manufacturing face masks are also discussed. Test methods and recent developments in face masks are briefly covered.

Suicide Attempts During Adolescence: Systematic Hospitalization and Crisis Treatment

Crisis ◽  
1999 ◽  
Vol 20 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Jérôme Ottino
Keyword(s):  
Attempted Suicide ◽  
Suicide Attempts ◽  
Psychiatric Treatment ◽  
Health Workers ◽  
Inpatient Unit ◽  
Theoretical Hypothesis ◽  
Initial Resistance ◽  
Provision Of Care ◽  
Suicidal Crisis

This paper deals with an inpatient unit that recently opened in Geneva, specializing in the treatment of patients aged 16-21 years who had attempted suicide or felt the desire to commit suicide. This particular center was established because of the significant weaknesses found in the provision of care to adolescents who had attempted suicide. Despite the growing interest of health workers in this area of study over recent years, the frequency of suicide among the young has not decreased and there are numerous recurrences of the suicide attempts. Further, all efforts to improve the adolescents' compliance with psychiatric treatment have failed to date. The number of drop-outs from treatment is still very high. Thus, the objectives of our inpatient unit are as follows: (1) to overcome initial resistance to treatment and to improve long-term compliance; (2) to decrease the number of recurrent attempts as a consequence of the above, thus increasing life expectancy; (3) to offer the adolescents who have tried (or have contemplated) committing suicide an improved quality of life, after first helping them overcome the suicidal crisis. To achieve these goals, the therapeutic team of the unit proposes short stays during which the work with the adolescents consists of a very intensive psychoanalytic-oriented crisis intervention. Numerous practical aspects of our therapeutic approach in the inpatient unit are related here in detail, always with reference to our theoretical hypothesis.

Cost-Effective Face Mask Filter Based on Hybrid Composite Nanofibrous Layers with High Filtration Efficiency

Langmuir ◽  
2021 ◽  
Author(s):  
Walaa A. Abbas ◽  
Basamat S. Shaheen ◽  
Loujain G. Ghanem ◽  
Ibrahim M. Badawy ◽  
Mohamed M. Abodouh ◽  
...  
Keyword(s):  
Hybrid Composite ◽  
Cost Effective ◽  
Face Mask ◽  
Filtration Efficiency

scholarly journals Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Ramesh Yelagandula ◽  
◽  
Aleksandr Bykov ◽  
Alexander Vogt ◽  
Robert Heinen ◽  
...  
Keyword(s):  
Influenza A ◽  
Respiratory Infections ◽  
High Sensitivity ◽  
Cost Effective ◽  
Massively Parallel ◽  
Rt Pcr ◽  
Viral Spread ◽  
Saliva Analysis ◽  
Double Blinded ◽  
Generation Sequencing

AbstractThe COVID-19 pandemic has demonstrated the need for massively-parallel, cost-effective tests monitoring viral spread. Here we present SARSeq, saliva analysis by RNA sequencing, a method to detect SARS-CoV-2 and other respiratory viruses on tens of thousands of samples in parallel. SARSeq relies on next generation sequencing of multiple amplicons generated in a multiplexed RT-PCR reaction. Two-dimensional, unique dual indexing, using four indices per sample, enables unambiguous and scalable assignment of reads to individual samples. We calibrate SARSeq on SARS-CoV-2 synthetic RNA, virions, and hundreds of human samples of various types. Robustness and sensitivity were virtually identical to quantitative RT-PCR. Double-blinded benchmarking to gold standard quantitative-RT-PCR performed by human diagnostics laboratories confirms this high sensitivity. SARSeq can be used to detect Influenza A and B viruses and human rhinovirus in parallel, and can be expanded for detection of other pathogens. Thus, SARSeq is ideally suited for differential diagnostic of infections during a pandemic.

scholarly journals Cost-effectiveness analysis of ranibizumab for retinal vein occlusion patients in China from the societal perspective

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Weiyi Ni ◽  
Jia Liu ◽  
Yawen Jiang ◽  
Jing Wu
Keyword(s):  
Cost Effectiveness ◽  
Retinal Vein Occlusion ◽  
Societal Perspective ◽  
Laser Photocoagulation ◽  
Cost Effective ◽  
Sensitivity Analyses ◽  
Gdp Per Capita ◽  
Base Case ◽  
Vein Occlusion ◽  
Per Capita

Abstract Background Clinical trials in China have demonstrated that ranibizumab can improve the clinical outcomes of branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO). However, no economic evaluation of ranibizumab has been conducted among Chinese patient population. Methods To provide insights into the economic profile of ranibizumab among Chinese RVO population, a Markov state-transition model was used to predict the outcomes of ranibizumab comparing to laser photocoagulation and observational-only care from the societal perspective. This model simulated changes in patient visuality, quality-adjusted of life years (QALY), medical costs, and direct non-medical costs of individuals with visual impairment due to BRVO or CRVO in lifetime. The base-case analysis used an annual discount rate of 5% for costs and benefits following the China Guidelines for Pharmacoeconomic Evaluations. Deterministic and probabilistic sensitivity analyses were performed to test the robustness of the model. Results The base-case incremental cost-effectiveness ratio (ICER) comparing ranibizumab to laser photocoagulation was ¥65,008/QALY among BRVO patients and was ¥65,815/QALY among CRVO patients, respectively. Comparing to the 2019 gross domestic product (GDP) per capita of ¥71,000, both two ICERs were far below the cost-effective threshold at three times of GDP per capita (¥213,000). The deterministic and probabilistic sensitivity analyses demonstrated the base-case results were robust in most of the simulation scenarios. Conclusion The current Markov model demonstrated that ranibizumab may be cost-effective compared with laser photocoagulation to treat BRVO and cost-effective compared to observation-only care to treat CRVO in China from the societal perspective.

Meta-analysis and cost effective analysis of portal-superior mesenteric vein resection during pancreatoduodenectomy: Impact on margin status and survival

2017 ◽  
Vol 26 (1) ◽  
pp. 53-62 ◽  
Author(s):  
Richard Bell ◽  
Braden Te Ao ◽  
Natasha Ironside ◽  
Adam Bartlett ◽  
John A. Windsor ◽  
...  
Keyword(s):  
Superior Mesenteric Vein ◽  
Meta Analysis ◽  
Cost Effective ◽  
Margin Status ◽  
Mesenteric Vein ◽  
Vein Resection ◽  
Effective Analysis

Determinants of Face Mask Utilization to Prevent Covid-19 Pandemic among Quarantined Adults in Tigrai Region, Northern Ethiopia, 2020

2021 ◽  
pp. 105477382110132
Author(s):  
Mekonnen Haftom ◽  
Pammla M. Petrucka
Keyword(s):  
Employment Status ◽  
Sampling Method ◽  
Respiratory Infections ◽  
Knowledge Score ◽  
Educational Status ◽  
Face Mask ◽  
Northern Ethiopia ◽  
Systematic Random Sampling ◽  
Vital Component ◽  
Study Participants

A face mask is a vital component of personal protective equipment to prevent potentially contagious respiratory infections. There was a lack of evidence showing the proportion and determinants of face mask use in Ethiopia. Therefore, this study aimed to identify face mask utilization determinants to prevent spread of the Covid-19 pandemic among quarantined adults in Tigrai region, northern Ethiopia. A total of 331 participants selected using a systematic random sampling method were included in the study. An interviewer-administered questionnaire was employed. After describing the variables using frequencies, means, and standard deviations, multivariable logistic regression determined factors associated with face mask utilization to prevent COVID-19 spread. The study participants were primarily males (70%) and mean age was 30.5 ( SD = 11) years. Nearly half of the participants reported they did not wear a face mask when leaving home. Face mask utilization was significantly associated with knowledge score, employment status, gender, age, and educational status of the study participants.

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