scholarly journals Multiple introductions followed by ongoing community spread of SARS-CoV-2 at one of the largest metropolitan areas in the Northeast of Brazil

Author(s):  
Marcelo Henrique Santos Paiva ◽  
Duschinka Ribeiro Duarte Guedes ◽  
Cassia Docena ◽  
Matheus Filgueira Bezerra ◽  
Filipe Zimmer Dezordi ◽  
...  

The emergence of SARS-CoV-2 in the human population has caused a huge pandemic that is still unfolding in many countries around the world. Multiple epicenters of the pandemic have emerged since the first pneumonia cases in Wuhan, first in Italy followed by the USA and Brazil. Up to now, Brazil is the second most affected country, however, genomic sequences of SARS-CoV-2 strains circulating in the country are restricted to some highly impacted states. Although the Pernambuco state, located in the Northeast Region, is the sixth most affected brazilian state and the second considering lethality rate, there is a lack of high quality genomic sequences from the strains circulating in this region. Here, we sequenced 38 strains of SARS-CoV-2 from patients presenting Covid-19 symptoms. Phylogenetic reconstructions revealed that three lineages were circulating in the state and 36 samples belong to B1.1 lineage. We detected two introductions from European countries and five clades, corroborating the community spread of the virus between different municipalities of the state. Finally, we detected that all except one strain showed the D614G spike protein amino acid change that may impact virus infectivity in human cells. Our study brought new light to the spread of SARS-CoV-2 strains in one of the most heavily impacted states of Brazil.

Viruses ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 1414
Author(s):  
Marcelo Henrique Santos Paiva ◽  
Duschinka Ribeiro Duarte Guedes ◽  
Cássia Docena ◽  
Matheus Filgueira Bezerra ◽  
Filipe Zimmer Dezordi ◽  
...  

Multiple epicenters of the SARS-CoV-2 pandemic have emerged since the first pneumonia cases in Wuhan, China, such as Italy, USA, and Brazil. Brazil is the third-most affected country worldwide, but genomic sequences of SARS-CoV-2 strains are mostly restricted to states from the Southeast region. Pernambuco state, located in the Northeast region, is the sixth most affected Brazilian state, but very few genomic sequences from the strains circulating in this region are available. We sequenced 101 strains of SARS-CoV-2 from patients presenting Covid-19 symptoms that reside in Pernambuco. Phylogenetic reconstructions revealed that all genomes belong to the B lineage and most of the samples (88%) were classified as lineage B.1.1. We detected multiple viral introductions from abroad (likely from Europe) as well as six local B.1.1 clades composed by Pernambuco only strains. Local clades comprise sequences from the capital city (Recife) and other country-side cities, corroborating the community spread between different municipalities of the state. These findings demonstrate that different from Southeastern Brazilian states where the epidemics were majorly driven by one dominant lineage (B.1.1.28 or B.1.1.33), the early epidemic phase at the Pernambuco state was driven by multiple B.1.1 lineages seeded through both national and international traveling.


2020 ◽  
Vol 5 ◽  
pp. 184 ◽  
Author(s):  
Pramod Kumar ◽  
Rajesh Pandey ◽  
Pooja Sharma ◽  
Mahesh S. Dhar ◽  
Vivekanand A. ◽  
...  

Background: India first detected SARS-CoV-2, causal agent of COVID-19 in late January 2020, imported from Wuhan, China. From March 2020 onwards, the importation of cases from countries in the rest of the world followed by seeding of local transmission triggered further outbreaks in India. Methods: We used ARTIC protocol-based tiling amplicon sequencing of SARS-CoV-2 (n=104) from different states of India using a combination of MinION and MinIT sequencing from Oxford Nanopore Technology to understand how introduction and local transmission occurred. Results: The analyses revealed multiple introductions of SARS-CoV-2 genomes, including the A2a cluster from Europe and the USA, A3 cluster from Middle East and A4 cluster (haplotype redefined) from Southeast Asia (Indonesia, Thailand and Malaysia) and Central Asia (Kyrgyzstan). The local transmission and persistence of genomes A4, A2a and A3 was also observed in the studied locations. The most prevalent genomes with patterns of variance (confined in a cluster) remain unclassified, and are here proposed as A4-clade based on its divergence within the A cluster. Conclusions: The viral haplotypes may link their persistence to geo-climatic conditions and host response. Multipronged strategies including molecular surveillance based on real-time viral genomic data is of paramount importance for a timely management of the pandemic.


2020 ◽  
pp. 163-169
Author(s):  
OKSANA CHEBERYAKO ◽  
VIKTOR KOLESNYK ◽  
ALINA GAIDUCHENKO

The beginning of the third millennium was marked by the desire of the leader countries (USA, China, and Russia) to geopolitical, geostrategic and geo-economic redistribution of spheres of influence. The collapse of the USSR, the dissolution of the Warsaw Pact Organization, the end of the Cold War did not bring the world closer to stability and security. Military force capabilities continue to be considered as one of the most powerful factors in world politics. Proof of this is the intensification of the struggle of the world›s superpowers for regional and global leadership, control over oil, gas and energy flows. It is worth mentioning the Transnistrian conflict, Russia-Led wars in South Ossetia and Abkhazia, the Russian-Georgian war in August 2008, the civil war in Syria, the intensification of Islamic extremism within the ISIS, Russia›s annexation of Crimea, the hybrid war unleashed and continues to wage by the Russian Federation against Ukraine. In this connection, it is becoming increasingly important to provide corresponding levels for the defense budget funding. Thus, the study of the peculiarities of defense financing in Ukraine and powerful military superpowers is of considerable scientific, practical and political interest. Comparing the defense expenditures of different countries makes it possible to identify key problem issues in the defense financing of Ukraine and bring the corresponding costs to international standards. This indicator is one of the most important criteria that characterize the state›s desire for development, relevant combat readiness of the armed forces and other military forces in the face of new challenges. The last years of the previous century were characterized by global geopolitical changes and growing contradictions, which resulted in: the transformation of the bipolar model (USA - USSR) into a multipolar (powerful military superpowers - the USA, Russia, China, Saudi Arabia, France, Japan, Germany, India, Brazil)); globalization of world economic processes; erosion through «hybrid wars», which are a new kind of global confrontation in today›s destabilized international security environment, the facets of the division between war and peace. The availability of weapons of mass destruction and high-precision weapons in the third millennium, the growth of their capacity, the complexity of military equipment and combat assets, the use of new methods and means of warfare have led to significant changes in the functions and tasks of the armed forces, increasing their number and government spending on defense purposes. Today there are about 200 armies in the world with a total number of 24-25 million people (about 0.4% of the world›s population) (Military..., 2002). The state of the troops of any state must correspond to its economic capabilities and at the same time ensure the implementation of national security tasks.


2021 ◽  
Vol 2021 (1) ◽  
pp. 22-35
Author(s):  
Iryna HUBARIEVA ◽  

The purpose of the article is to reveal the peculiarities of real estate taxation of individuals in the countries of the world and to develop recommendations for its improvement in Ukraine. The features of taxation of real estate of individuals in the USA, Germany, Sweden, Poland, Bulgaria, Italy, France, Great Britain, Lithuania and others are presented. The advantages and disadvantages of taxation of real estate of individuals in the countries of the world are identified. Attention is focused on methods for determining the cadastral / assessed value of real estate for taxation. The necessity of reforming the system of taxation of real estate of individuals in Ukraine has been proved. The introduction of a cost approach to the appraisal of real estate in Ukraine requires a number of sequential actions: centralization of management and maintenance of the real estate cadastre in one state governing body; development of regulatory support for the creation and operation of the State cadastre of real estate, the mechanism and methods of state cadastral valuation; inventory of real estate objects with the assignment of a cadastral number; formation of the system of the State cadastre of real estate. The approaches to the establishment of tax exemptions on real estate of individuals in the countries of the world and in Ukraine have been investigated. In Ukraine, the basis for taxation of real estate of individuals should be the cadastral / assessed value of real estate with its gradual approach to the market value. The introduction of a cost approach to the appraisal of real estate in Ukraine requires: centralization of competences in one state governing body; development of regulatory support for the creation and functioning of the State cadastre of real estate, the mechanism and methods of state cadastral valuation; inventory of real estate objects with the assignment of a cadastral number; formation of the system of the State cadastre of real estate; taking into account the experience in the formation of the Land Cadastre, it is necessary to ensure the transparency of the tax on real estate of individuals through digitalization of tax services and administration processes (obtaining in electronic form a certificate of the cadastral / estimated value of property by cadastral number or postal address, paying tax for the Electronic Cabinet, having access to information on the procedure for calculating tax on each property, tax rates, the availability of benefits, debts, payment history, etc.). When levying a tax on real estate, it is necessary to assess feasibility of applying tax incentives in terms of differentiating the standard of living of the population in Ukraine in order to protect socially unprotected segments of the population. Property tax benefits for individuals should be linked to the cadastral / assessed value of the property by establishing a non-taxable minimum amount of the assessed value of the property and apply to only one residential property where the owner permanently resides.


2020 ◽  
pp. 86-95
Author(s):  
D.D. Tymoshyk ◽  
L.L. Hrytsenko ◽  
Ya.S. Kovalev

The article considers the concept of small and medium enterprises in the process of economic thought formation. The task of the work is to determine and analyze the state of small and medium business in Ukraine and abroad. For this, the definitions of foreign and national scholars are outlined and their own understanding of the term is formulated. A comparative and quantitative analysis of enterprises was conducted on the basis of data collected by the State Statistics Service of Ukraine, and a positive increase in enterprises for the period 2014-2018 was revealed. In addition, the main approaches to the division of enterprises into types according to different classification criteria due to the Ukrainian economic system and the standards of the European Union, which fundamentally differ from the division system in the United States, are studied. At the same time, the indicators of small and medium-sized enterprises of the USA and European countries are considered, that allows us to say that the largest percentage of the contribution to GDP belongs to the small and medium-sized enterprise sector. The described features of SMEs in comparison with other types of enterprises determine the importance of SMEs as a stable and self-sufficient sector of the economy which requires support from government regulation. The urgency of research on the topic of SMEs is primarily dictated by the need to summarize the previously studied layers of this topic, the emergence of new reforms and Ukraine’s desire to improve the economic system and bring it to the world level. Economic development depends not only on internal policy principles, but also on external factors influencing the state of the world economy. The beginning of 2020 made the leaders of the world community think about the principles of maintaining economic indicators during the trigger caused by the coronavirus pandemic and the collapse of oil prices, and therefore it is natural to implement programs to support small and medium enterprises during the global recession.


2018 ◽  
Vol 14 (2) ◽  
pp. 16-25
Author(s):  
Olena Dobrovolska ◽  
José Manuel Recio Espejo

The development of the organic market in the world requires conducting a research on the problems that accompany this process. Such studies are becoming more popular and apply not only to organic products market at the global level, but also at the local level. In order to identify global problems, the state and trends of the organic products markets in the USA, Germany, France, Britain as the biggest national markets were analyzed on the basis of the data characterizing the state of organic products market in Ukraine and in the world, provided by the Research Institute of Organic Agriculture (FIBL) and the International Federation of Organic Agricultural Movements (IFOAM). The research of the state and trends of the Ukrainian organic market and agricultural production development was conducted, and using the SWOT analysis methodology and the principles laid out in the PEST analysis, its strengths and weaknesses, opportunities and threats were identified. Within each element, social, environmental, economic and financial constituents have been grouped, providing a possibility to understand which factor is determining in terms of sustainable development. It enabled to make a conclusion that the Ukrainian market remains small in size, entailing significant risks, first of all, for producers, as its further development requires a significant all-round support from the state both from the financial point of view and from the point of view of active promotion of sustainable development ideas and education of the population on the importance of consuming quality products, taking care about their health and, as a result, contributing to the improvement of the environment.


Author(s):  
Igor Mikhalskiy ◽  
◽  
Bohdan Toroptsev ◽  

Foreign policy of the USA is one of the topical areas in contemporary historical and geopolitical research. The interest of scientists in this topic is due to the fact that the United States is the leader of the world community at the present stage, both in economic and geopolitical aspects. The state continues to actively develop economically and technologically, increases its military potential, actively spreads its culture all over the world, that determines its global role. The phenomenon of the world leadership of the USA, as well as the historical factors that have determined this status, are the subject of research of scientists in the historical, geopolitical, politological, sociological, cultural, and other scientific fields. A particularly topical issue in the history of the United States in the second half of the twentieth century is the concept and specificity of American „shuttle diplomacy” and its effectiveness in the foreign policy of the state. The purpose of the study is to analyze the concept of the American geographer S. Cohen, as well as the peculiarities of its implementation in the political activities of R. Nixon and H. Kissinger. It has been proved that S. Cohen's geostrategic concept played an important role in the foreign policy of the United States in the 1970s. Its principles were implemented in the policy of H. Kissinger and R. Nixon, the important results of which were the establishment of United States-China relations and the softening of relations with the Soviet Union.


2006 ◽  
pp. 75-92 ◽  
Author(s):  
S. Moiseev

The number of classical banks in the world has reduced. In the majority of countries the number of banks does not exceed 200. The uniqueness of the Russian banking sector is that in this respect it takes the third place in the world after the USA and Germany. The paper reviews the conclusions of the economic theory about the optimum structure of the banking market. The empirical analysis shows that the number of banks in a country is influenced by the size of its territory, population number and GDP per capita. Our econometric estimate is that the equilibrium number of banks in Russia should be in a range of 180-220 units.


Sign in / Sign up

Export Citation Format

Share Document