scholarly journals Serum Oxidative Stress Markers in Women with Uterine Fibroids in Lagos, Nigeria.

2021 ◽  
Author(s):  
Adaiah Priscillia Soibi-Harry ◽  
Christian Makwe ◽  
Ayodeji Ayotunde Oluwole ◽  
Sunusi-Rimi Garba ◽  
Abisoye Towuromola Ajayi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Negative Correlation ◽  
Uterine Fibroids ◽  
Serum Levels ◽  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Stress Markers ◽  
Median Serum ◽  
Reproductive Age Group

ABSTRACT Background: Uterine fibroid is the most common benign gynaecological tumour in women of reproductive age group, with significant impact on the quality of life, economy, morbidity and sometimes mortality of affected women. Black women of reproductive age group are more likely to develop uterine fibroids. Although available evidence suggests racial and genetic predisposition to the aetiology of uterine fibroid, oxidative stress has been implicated in the onset and progression of uterine fibroids. Epidemiological and experimental studies have suggested that oxidative stress may play an important role in the pathogenesis of gynaecological diseases including uterine fibroids. Aim and Objectives: This study aims to assess the serum levels of antioxidants (catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx)) and oxidants (protein carbonyl (PC), advanced oxidation protein products (AOPP)) in women with uterine fibroids and to identify any association between the size of uterine fibroids and serum levels of the analysed antioxidants and oxidants. Methods: Forty-four women with ultrasound diagnosis of uterine fibroids and 44 women without uterine fibroids were recruited from a University Teaching Hospital. Blood samples were obtained and analysed for serum levels of selected antioxidants (CAT, SOD, GPx) and oxidants (PC, AOPP). Pelvic ultrasonography was performed on all study participants. Results: The median serum levels of antioxidants: CAT (2.20 vs 4.32 ng/ml; p < 0.001); SOD (285.54 vs 380.96 ng/ml; p < 0.001) and GPx (9.67 vs 11.26 uU/ml; p < 0.001) were significantly lower in women with uterine fibroids. The median serum levels of oxidants: PC (162.08 vs 142.36 ng/ml; p = 0.04); and AOPP (22.42 vs 13.94 ng/ml; p < 0.001) were significantly higher in women with uterine fibroids. There was a strong negative correlation between serum levels of AOPP and SOD (r = -0.95; p < 0.001) in women with uterine fibroids. The maximum diameter of fibroids showed a significant positive correlation with AOPP (r = 1.000; p < 0.001) and a negative correlation with SOD (r = -1.000; p < 0.001). Conclusion: Women with uterine fibroids had lower levels of antioxidants and higher levels of oxidants. In women with uterine fibroids, AOPP negatively correlated with SOD. There was a positive correlation between fibroid size and AOPP and a negative correlation between fibroid size and SOD. The findings of this study suggests that AOPP and SOD may play an important role in uterine fibroids. Keywords: Uterine fibroids; Oxidative stress markers; antioxidants; oxidants

scholarly journals Predictors and symptomatic burden of uterine fibroids among women in South-Eastern India: a cross-sectional survey analysis

2019 ◽  
Vol 8 (2) ◽  
pp. 524
Author(s):  
Dharitri Swain ◽  
Chanchal Yadav ◽  
Jyoti Kumari ◽  
Monika Rani ◽  
Priyanka Daunrai Rongmei ◽  
...  
Keyword(s):  
Risk Factors ◽  
Uterine Fibroid ◽  
Uterine Fibroids ◽  
Overweight And Obesity ◽  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Cross Sectional ◽  
Associated Risk Factors ◽  
Reproductive Age Group

Background: Uterine fibroid is the most common pelvic tumor in women of reproductive age and are asymptomatic in at least 50% of affected women. Various risk factors are associated with development of uterine fibroids during this reproductive age. The present study established various associated risk factors increases the prevalence of uterine fibroid among reproductive age group and clinical symptoms burden of diagnosed case.Methods: A cross sectional study design was used to collect samples for a period of six months in an OPD basis. Purposive sampling technique was used to select the 362 sample of reproductive age group (15-45 years) women in a tertiary care hospital, Southeastern India. Women diagnosed with uterine fibroid by ultrasonography were included as cases. Symptomatic features and associated risk factors of UF were collected through structure interview schedule.Results: Point prevalence of uterine fibroid among women in reproductive age group during the period of six months was 20%. Majority of them were in the age group of 30-39 years. Demographic factor such as overweight and obesity and consume dairy products daily has increased the prevalence of UF, whereas use of oral contraceptive pills and normal BMI had inverse relationship with UF risk. Most of the cases reported of having menstrual disturbances like heavy bleeding, passes blood clots during menstruation, prolonged period, urinary symptoms and pressure symptoms were considered independent predicting factors for the occurrence of uterine fibroid.Conclusions: Uterine fibroid is more prevalent among women of reproductive age causing various bleeding and renal symptoms that can have negative impact on quality of women’s life.

scholarly journals Prevalence of Goiter and Associated Factors among Women of Reproductive Age Group in Demba Gofa Woreda, Gamo Gofa Zone, Southwest Ethiopia: A Community-Based Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Befikaduwa Zekarias ◽  
Frehiwot Mesfin ◽  
Bezatu Mengiste ◽  
Adane Tesfaye ◽  
Lemma Getacher
Keyword(s):  
Logistic Regression ◽  
Iodine Deficiency ◽  
Associated Factors ◽  
Sampling Technique ◽  
Iodized Salt ◽  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Cross Sectional ◽  
Reproductive Age Group

Background. Iodine deficiency disorder is a major public health problem in Ethiopia that is more common in women of reproductive age. However, it is not well addressed and there is a lack of information on its prevalence and associated factors in women of reproductive age group. Therefore, the objective of this study was to assess goiter prevalence and associated factors among women of reproductive age in the Demba Gofa woreda, Gamo Gofa Zone, Southwest Ethiopia. Methods. A community-based cross-sectional study was used among 584 randomly selected women in the reproductive age group from February 05 to April 20, 2016. A simple random sampling technique was used to select the study kebeles, and a systematic random sampling technique was used to select the study samples. Data were collected through a pretested questionnaire, and the goiter examination was done clinically for each participant. The collected data were coded and entered into a computer for statistical analysis using EpiData version 3.2 and analyzed using SPSS version 20. Variables with a P value ≤0.25 in bivariate logistic regression analysis were entered into multivariate logistic regression analysis, and finally, variables with a P value <0.05 in multivariate logistic regression were considered significantly associated with the dependent variable. Results. The total goiter rate was 43%, 95% CI = 39.2–46.9. Cassava consumption (AOR: 2.02, 95% CI: 1.03–4), salt wash before use (AOR: 3.14, 95% CI: 1.1–11.3), salt use after >2 months of purchase (AOR: 11, 95% CI: 5–26), family history of goiter (AOR: 4.6, 95% CI: 1.4–15.8), and poor knowledge of iodized salt (AOR: 2.7, 95% CI: 1.4–5.5) were significant factors associated with goiter. Conclusion. Iodine deficiency was found to be severe in women of reproductive age in the study area. This showed that women of reproductive age, especially during pregnancy, are exposed to iodine deficiency and its adverse effects at delivery. Thus, they need urgent supplementation with iodine, improved access to foods rich in iodine, and intake of iodized salt. Additionally, health education should focus on the importance of iodized salt, the proper method of use, and the prevention of iodine deficiency, which are highly recommended to minimize the problem.

Preference on prenatal sex determination and its associated factors among currently married women of reproductive age group in Puducherry, India

2021 ◽  
Vol 28 (1) ◽  
pp. 51
Author(s):  
GaneshKumar Saya ◽  
KariyarathCheriyath Premarajan ◽  
Gautam Roy ◽  
Sonali Sarkar ◽  
SitanshuSekhar Kar ◽  
...  
Keyword(s):  
Sex Determination ◽  
Associated Factors ◽  
Married Women ◽  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Reproductive Age Group

Bacterial Vaginosis and its Relation with Sociodemographic Determinants in married reproductive age females

2021 ◽  
Vol 15 (6) ◽  
pp. 1249-1252
Author(s):  
R. Mukhtar ◽  
A. U.- Rehman ◽  
A. Ilyas ◽  
M. J. Khan ◽  
R. Liaqat ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Bacterial Vaginosis ◽  
Vaginal Discharge ◽  
Pap Smear ◽  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Sociodemographic Determinants ◽  
Reproductive Age Group ◽  
Nonspecific Inflammation

Aim: To determine the frequency of Bacterial vaginosis by pap smear cytology and find its association with its sociodemographic determinants. Study design: Cross sectional analytical study Place and duration of study: Department of Histopathology, Shaikh Zayed Hospital, Lahore from 1st January 2016 to 31st October 2016. Methodology: Two hundred and sixty pap smears of married women of reproductive age group with vaginal discharge who attended Gynecology OPD were included. Proper history regarding age, socioeconomic status, age of marriage, literacy level, smoking, and nutritional status was taken. Results: Disease prevalence was found to be 19.2%(50)in this sample of 260 while 9.1% had Candidiasis, 47%, 17.2% ,3.7%, 4.1% had Mild nonspecific inflammation, Moderate nonspecific inflammation, Moderate to severe nonspecific inflammation, and negative smears respectively. Bacterial vaginosis was associated with age, monthly income, illiteracy, early age at marriage, history of abortion and nutritional status with significant p-value ≤ 0.05. However no association was found between the disease and marital status, smoking and pallor. Conclusion: Low socioeconomic status, literacy, age >35, nutritional status is strongly related to occurrence of bacterial vaginosis in women of reproductive age group with vaginal discharge. Key Words: Bacterial vaginosis, Pap smear, Sociodemographic determinants

Prevalence of anemia among tribal women of reproductive age-group in Wayanad district of Kerala

2014 ◽  
Vol 3 (2) ◽  
pp. 120 ◽  
Author(s):  
BM Shrinivasa ◽  
RekhaRachel Philip ◽  
VijayaKumar Krishnapali ◽  
Asha Suraj ◽  
PR Sreelakshmi
Keyword(s):  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Tribal Women ◽  
Reproductive Age Group ◽  
Prevalence Of Anemia

scholarly journals Associated factors of pregnancy spacing among women of reproductive age Group in South of Iran: cross-sectional study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Tania Dehesh ◽  
Elaheh Salarpour ◽  
Neda Malekmohammadi ◽  
Sepideh Arjomand Kermani
Keyword(s):  
Cross Sectional Study ◽  
Reproductive Age ◽  
Recurrent Event ◽  
Age Group ◽  
Sectional Study ◽  
Women Of Reproductive Age ◽  
Cross Sectional ◽  
Pregnancy Spacing ◽  
Contraception Use ◽  
Reproductive Age Group

Abstract Background Optimal pregnancy spacing is an important incidence in reproductive women’s health. Short or long pregnancy spacing leads to the greatest health, social and economic problems such as increase in maternal and infant mortality and morbidity, and adverse pregnancy outcomes. The aim of this study is to assess the mean of pregnancy spacing and associated factors of pregnancy spacing among women of reproductive age group with recurrent event analysis. Methods The fertility history of 1350 women aged 15–49 years was collected in this cross-sectional study. The women were selected through multistage random sampling method from a list of clinics in 2018. Some predictors were collected from their records and others were collected by face-to-face interview. The recurrent event survival analysis was used to explore the effect of predictors on pregnancy spacing. The R software program was used for analysis. Results There were nine predictors that had significant effect on pregnancy spacing. These predictors included the age of mother at marriage, mother’s BMI, contraception use, breast feeding duration of the previous child, the education level of husband, the sex preference of the mother, presence of abortion or stillbirth in the preceding pregnancies, income sufficiency, and mother’s awareness of optimum pregnancy interval. The most influential predictors; contraception use (HR = 2.34, 95%CI = 1.23 to 2.76, P < 0.001) and income sufficiency (HR = 2.046, 95%CI = 1.61 to 3.02, P = 0.018) lead to longer and son preference of mother (HR = 2.231, 95%CI = 1.24 to 2.81, P = 0.023) lead to shorter pregnancy spacing. Conclusion The up to date contraception tool should be at hand for couples to manage their pregnancy intervals. The unfavorable economic situation of a family leads to long pregnancy spacing. Despite the relative equality of the status of girls and boys in today’s societies, the desire to have a son child is still an important factor in shorter pregnancy spacing. The benefit of optimal pregnancy spacing should be more announced.

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