Development of a high-level feasibility analysis model for the selection of railway upgrade options

Author(s):  
Xindi Chen ◽  
Gemma L. Nicholson ◽  
Clive Roberts
Author(s):  
Sri G. Thrumurthy ◽  
Tania Samantha De Silva ◽  
Zia Moinuddin ◽  
Stuart Enoch

Specifically designed to help candidates revise for the MRCS exam, this book features 350 Single Best Answer multiple choice questions, covering the whole syllabus. Containing everything candidates need to pass the MRCS Part A SBA section of the exam, it focuses intensively on the application of basic sciences (applied surgical anatomy, physiology, and pathology) to the management of surgical patients. The high level of detail included within the questions and their explanations allows effective self-assessment of knowledge and quick identification of key areas requiring further attention. Varying approaches to Single Best Answer multiple choice questions are used, giving effective exam practice and guidance through revision and exam technique. This includes clinical case questions, 'positively-worded' questions, requiring selection of the most appropriate of relatively correct answers; 'two-step' or 'double-jump' questions, requiring several cognitive steps to arrive at the correct answer; as well as 'factual recall' questions, prompting basic recall of facts.


2021 ◽  
Vol 14 (7) ◽  
pp. 603
Author(s):  
Vanesa Pérez-Laguna ◽  
Isabel García-Luque ◽  
Sofía Ballesta ◽  
Antonio Rezusta ◽  
Yolanda Gilaberte

The present review covers combination approaches of antimicrobial photodynamic therapy (aPDT) plus antibiotics or antifungals to attack bacteria and fungi in vitro (both planktonic and biofilm forms) focused on those microorganisms that cause infections in skin and soft tissues. The combination can prevent failure in the fight against these microorganisms: antimicrobial drugs can increase the susceptibility of microorganisms to aPDT and prevent the possibility of regrowth of those that were not inactivated during the irradiation; meanwhile, aPDT is effective regardless of the resistance pattern of the strain and their use does not contribute to the selection of antimicrobial resistance. Additive or synergistic antimicrobial effects in vitro are evaluated and the best combinations are presented. The use of combined treatment of aPDT with antimicrobials could help overcome the difficulty of fighting high level of resistance microorganisms and, as it is a multi-target approach, it could make the selection of resistant microorganisms more difficult.


2013 ◽  
Vol 25 (1) ◽  
pp. 89-118 ◽  
Author(s):  
John C. Paolillo

AbstractIndividual-level variation is a recurrent issue in variationist sociolinguistics. One current approach recommends addressing this via mixed-effects modeling. This paper shows that a closely related model with fixed effects for individual speakers can be directly estimated using Goldvarb. The consequences of employing different approaches to speaker variation are explored by using different model selection criteria. We conclude by discussing the relation of the statistical model to the assumptions of the research design, pointing out that nonrandom selection of speakers potentially violates the assumptions of models with random effects for speaker, and suggesting that a model with fixed effects for speakers may be a better alternative in these cases.


The selection of hospital sites is one of the most important choice a decision maker has to take so as to resist the pandemic. The decision may considerably affect the outbreak transmission in terms of efficiency , budget, etc. The main targeted objective of this study is to find the ideal location where to set up a hospital in the willaya of Oran Alg. For this reason, we have used a geographic information system coupled to the multi-criteria analysis method AHP in order to evaluate diverse criteria of physiological positioning , environmental and economical. Another objective of this study is to evaluate the advanced techniques of the automatic learning . the method of the random forest (RF) for the patterning of the hospital site selection in the willaya of Oran. The result of our study may be useful to decision makers to know the suitability of the sites as it provides a high level of confidence and consequently accelerate the power to control the COVID19 pandemic.


Author(s):  
Steven M. Wilkerson ◽  
Satish Nagarajaiah

As the oil offloading operations of floating production storage and offloading (FPSO) units become more routine, the desire grows to increase the availability for offloading and thus decrease production downtime. Experience with these operations is the main tool available to increase the efficiency of this aspect of deepwater production. However, it is clear that a formal optimization approach can help to fine tune design parameters so that not only is availability increased but the significance of each design parameter can be better understood. The key issue is to define the environmental conditions under which the vessels involved in offloading are able to maintain position. By this, we reduce the notion of availability to a set of operating criteria, which can or cannot be met for a particular set of environmental conditions. The actual operating criteria such as relative vessel heading depend on selection of design parameters, such as the direction and magnitude of external force applied by thrusters or tugs. In the earliest offloading operations, engineering judgment was used to determine the feasibility of offloading at a particular time. For example, if wind and current were not expected to exceed a 1year return period, offloading may be considered safe. This approach can be both conservative and unconservative, depending on the nuances of the particular environmental conditions. This study will propose a formal approach to choosing the design parameters that optimize the availability of a FPSO for offloading. A simple analysis model will be employed so that optimization can be performed quickly using a robust second order method. The proposed analysis model will be compared to model test data to demonstrate its agreement with the more complex system.


2017 ◽  
Vol 52 (sup1) ◽  
pp. 17-24 ◽  
Author(s):  
Didier Crusset ◽  
Valérie Deydier ◽  
Sophia Necib ◽  
Jean-Marie Gras ◽  
Pierre Combrade ◽  
...  

2017 ◽  
Vol 11 (3) ◽  
pp. 51-58
Author(s):  
Татьяна Никонова ◽  
Tatyana Nikonova ◽  
Валерия ГУСАРОВА ◽  
Valeriya GUSAROVA ◽  
Ольга Пережогина ◽  
...  

In the last few years, the development of adventure tourism as a kind of active tourism initiatives, tourism firms have become more visible. Adventuretourism (adventure tourism) is different in originality and unusual variety of tours. It includes exotic travel, extreme sports, a specific move connected with risk and danger to life. In this regard, the article highlights the criterion of the differences of adventure tourism from other types of active travel. The authors point out the the main reasons for the popularity of adventure tourism of the article, among which are following: healthy lifestyle popularization, prestige of the activity of the pleasure, the desire of the modern tourist for new experiences and the rush of emotion, the possibility of self-realization, improving credibility and promotion in society through adventure tourism, including with help of social networks. Taking into account the growing popularity of adventure tourism in the world, the authors of the article analyzes the factors of Russia’s competitiveness for the adventure tourism development. It is revealed that strengths are rail transport infrastructure and a high level of health and hygiene. The article admits that now the development of adventure tourism in Russia is constrained by a number of negative factors to be overcome. Among them are the lack of a comprehensive look at the geography of Russia from the standpoint of the selection of adventure territories, the unsatisfactory level of tourist infrastructure of adventure, poor range and low quality of ser- vices adventure tourism, weak professional background of the staff.


2019 ◽  
pp. 22-26
Author(s):  
O. Goryacheva

The identification of mechanisms for the implementation of public relations and the selection of effective internal PR tools can affect the organization’s management. The main objective of internal PR is to stabilize the workforce and increase employee satisfaction. The possibilities of internal PR in the formation and maintenance of corporate culture have been investigated in the article. The indicators of labor assessment presented not only help determine the level of professionalism of the employee, but also demonstrate his personalized labor achievements to the whole team. The motivation of the participants of the labor process to the awareness of the importance of the implementation of the collective tasks has a beneficial effect on the formation of corporate culture. Monitoring of events and internal PR tools will allow you to adjust the formation of corporate culture and provide a high level of management at the enterprise.


2021 ◽  
pp. 172-181
Author(s):  
Oksana Y. Vasileva ◽  
Marina V. Nikulina Nikulina ◽  
Juri I. Platov Platov

The article deals with the problem of selecting efficient ships by the feasibility study in which brake power, main dimensions, payload, speed and fuel consumption are determined. The necessity of using the proposed selection at the initial stage of the ship's design is justified; the problems that arise at the present time are denoted. The purpose of the article is to propose a criterion for the selection of efficient vessels, "tied" to the operating conditions, based on the marginal cost of the ship. A method for its determination is presented. At the same time, annual revenues and operating costs should be determined by modern methods of business planning for the operation of the fleet. When searching for the parameters of the ship, the optimal fuel consumption is determined. The rest of the costs can be found according to the coefficients "tied" to the fuel consumption and calculated on the basis of existing prototypes. The results of calculations by the proposed method are shown; its merits and opportunities for improvement are noted with the availability of relevant information. The conclusion is made about the convenience and applicability of the proposed option for selecting efficient ship for the feasibility study based on optimization methods for determining the parameters of vessels under conditions of a high level of use of information technologies.


2014 ◽  
Vol 62 (3) ◽  
pp. 571-582 ◽  
Author(s):  
J.M. Kościelny ◽  
M. Syfert

Abstract The survey presents a selection of the methods of the fault detection and isolation suitable to be useful for the diagnostics of the complex, large scale industrial processes. The paper focuses on these methods that have appropriately high level of potential applicability in industrial practice. The novelty of the paper relies on the discussion of the dependency of the level of knowledge about diagnosed process and recommended diagnostic approaches. Appropriate recommendations were given in the convenient form of the table


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